Page last updated: 2024-08-22

cyclazocine and naltrexone

cyclazocine has been researched along with naltrexone in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	82 (95.35)	18.7374
1990's	3 (3.49)	18.2507
2000's	1 (1.16)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH	2
Altman, JL; Meyer, RE; Mirin, SM	1
Altman, JL; McNamee, HB; Meyer, RE; Mirin, SM	2
Bell, J; Gilbert, P; Martin, W; Sloan, J; Thompson, J	1
Julius, D	1
Archer, S; Michne, WF	1
Wikler, A	2
Martin, WR	2
Greenstein, R; O'Brien, CP; Ternes, J; Testa, T	1
Fennessy, MR; Laska, FJ	1
Brahen, LS; Capone, T; Wojak, JC	1
Resnick, RB	1
Kaim, SC	1
Cooperstein, J; Harris, M; Hough, G; Kauders, F; Resnick, R; Thomas, M	1
Brocco, MJ; Killam, KF; Robinson, CA	1
Brahen, LS; Capone, T; Desiderio, D; Wiechert, V	1
Swanson, DA	1
Eades, CG; Gilbert, PE; Huppler, RE; Martin, WR; Thompson, JA	1
Foldes, FF; Knoll, J; Rich, J; Vizi, ES	1
Blaiklock, RG; Hirsh, EM; Hui, FW; Krikun, E; Smith, AA	1
Jaffe, J	1
Calesnick, B	1
LoPresti, D; Porreca, F; Ward, SJ	1
Goldberg, SR; Katz, JL; Schindler, CW; Su, TP; Wu, XZ	1
Holtzman, SG	4
Dougall, IG; Leff, P	2
Brocklehurst, C; Devia, C; Faust, WB; Moerschbaecher, JM	1
Burks, TF; Fox, DA	1
Larson, DL; Lipkowski, AW; Nagase, H; Portoghese, PS; Takemori, AE	1
Nagase, H; Portoghese, PS; Takemori, AE	1
Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE	1
Carino, MA; Horita, A; Yamawaki, S	1
Martin, WR; Wettstein, JG	1
Lipkowski, AW; Portoghese, PS; Takemori, AE	1
Portoghese, PS; Takemori, AE	2
Eisenberg, RM	1
Carr, KD; Feliu, AL; Fowler, JS; Holland, MJ; Simon, EJ	1
Bell, RD; Cicero, TJ	1
Hiramatsu, M; Kameyama, T; Nabeshima, T	1
Hayes, AG; Skingle, M; Tyers, MB	1
Larson, DL; Portoghese, PS; Ronsisvalle, G; Takemori, AE	1
Liu-Chen, LY; Tam, SW	1
Bhargava, HN; Das, S	2
Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM	1
Portoghese, PS; Schoenecker, JW; Takemori, AE	1
Calcagnetti, DJ; Cramer, CP; Fanselow, MS; Helmstetter, FJ	1
Calligaro, D; Khazan, N; Young, GA	1
Dykstra, LA; Gmerek, DE; Winger, G; Woods, JH	1
Brocklehurst, C; Devia, C; Moerschbaecher, JM	1
Balster, RL; Slifer, BL	1
Moerschbaecher, JM; Thompson, DM; Winsauer, PJ	1
Leander, JD	1
Ludens, JH; Slizgi, GR	1
Stephens, KR; Young, AM	1
Terenius, L	1
Cheng, RS; Pomeranz, BH	1
Holtzman, SG; Teal, JJ	3
Kosterlitz, HW; Paterson, SJ; Robson, LE	1
Harris, RA; Snell, D	1
Portoghese, PS; Takemori, AE; Ward, SJ	1
Takemori, AE; Ward, SJ	1
Brown, DR; Holtzman, SG; Locke, KW	1
Herling, S; Solomon, RE; Valentino, RJ; Woods, JH	1
Holtzman, SG; White, JM	2
Franklin, SR; Tang, AH	1
Hein, DW; Herling, S; Woods, JH; Young, AM	1
Herling, S; Woods, JH; Young, AM	1
Woods, JH; Young, AM	1
Herling, S; Valentino, RJ; Woods, JH	1
Jasinski, DR	1
Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ	1
Bidlack, JM; Cioffi, CL; Cohen, DJ; Colasurdo, AM; Duan, W; Wentland, MP; Xu, G; Ye, Y	1

Reviews

5 review(s) available for cyclazocine and naltrexone

Article	Year
NIDA's naltrexone research program. NIDA research monograph, 1976, Issue:9 Topics: Clinical Trials as Topic; Conditioning, Psychological; Cyclazocine; Drug Evaluation; Euphoria; Heroin; Heroin Dependence; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Research; Research Support as Topic; United States; United States Substance Abuse and Mental Health Services Administration	1976
Recent progress in research on narcotic antagonists. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1976, Volume: 20 Topics: Animals; Benzomorphans; Chemical Phenomena; Chemistry; Cyclazocine; Humans; In Vitro Techniques; Models, Biological; Morphinans; Morphine Derivatives; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Receptors, Opioid; Structure-Activity Relationship; Substance-Related Disorders; Thebaine	1976
Methadone maintenance and narcotic blocking drugs. Appendix. The International journal of the addictions, 1977, Volume: 12, Issue:7 Topics: Administration, Oral; Cyclazocine; Drug Tolerance; Heroin Dependence; Humans; Injections, Subcutaneous; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Research; Substance Withdrawal Syndrome	1977
Evolution of the National Academy of Sciences study of naltrexone. NIDA research monograph, 1976, Issue:9 Topics: Academies and Institutes; Clinical Trials as Topic; Cyclazocine; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Research Design; Research Support as Topic	1976
Limitations on the antagonistic actions of opioid antagonists. Federation proceedings, 1982, Volume: 41, Issue:7 Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Cyclazocine; Macaca mulatta; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saimiri	1982

Trials

5 trial(s) available for cyclazocine and naltrexone

Article	Year
NIDA's naltrexone research program. NIDA research monograph, 1976, Issue:9 Topics: Clinical Trials as Topic; Conditioning, Psychological; Cyclazocine; Drug Evaluation; Euphoria; Heroin; Heroin Dependence; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Research; Research Support as Topic; United States; United States Substance Abuse and Mental Health Services Administration	1976
The double-blind crossover trial design: how good is it for psychoactive drugs? The American journal of drug and alcohol abuse, 1979, Volume: 6, Issue:2 Topics: Adult; Cyclazocine; Double-Blind Method; Humans; Male; Naloxone; Naltrexone; Opioid-Related Disorders	1979
Evolution of the National Academy of Sciences study of naltrexone. NIDA research monograph, 1976, Issue:9 Topics: Academies and Institutes; Clinical Trials as Topic; Cyclazocine; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Research Design; Research Support as Topic	1976
Clinical experiences with naltrexone in 370 detoxified addicts. NIDA research monograph, 1976, Issue:9 Topics: Clinical Trials as Topic; Cyclazocine; Drug Administration Schedule; Humans; Methadone; Naloxone; Naltrexone; Patient Compliance; Physicians; Placebos; Research Personnel; Substance-Related Disorders	1976
Naltrexone and cyclazocine. A controlled treatment study. Archives of general psychiatry, 1977, Volume: 34, Issue:10 Topics: Administration, Oral; Adult; Cyclazocine; Double-Blind Method; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Placebos; Self-Assessment	1977

Other Studies

78 other study(ies) available for cyclazocine and naltrexone

Article	Year
Narcotic drug discriminations by rhesus monkeys and pigeons. NIDA research monograph, 1979, Volume: 27 Topics: Animals; Columbidae; Cyclazocine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Discrimination Learning; Dose-Response Relationship, Drug; Enkephalins; Ethylketocyclazocine; Etorphine; Hormones; Macaca; Macaca mulatta; Naltrexone; Narcotics; Phenazocine	1979
The clinical usefulness of narcotic antagonists: implications of behavioral research. The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4 Topics: Aftercare; Behavior Therapy; Conditioning, Operant; Cyclazocine; Extinction, Psychological; Heroin; Heroin Dependence; Hospitalization; Humans; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Patient Dropouts; Reinforcement, Psychology; Research Design; Self-Assessment	1975
Analysis and modification of opiate reinforcement. The International journal of the addictions, 1976, Volume: 11, Issue:3 Topics: Adult; Aftercare; Behavior Therapy; Boston; Cyclazocine; Follow-Up Studies; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Patient Dropouts; Reinforcement, Psychology; Token Economy	1976
The effects of naltrexone in the chronic spinal dog and acute spinal cat; possible interaction with naturally-occurring morphine-like agonists. NIDA research monograph, 1976, Issue:9 Topics: Animals; Brain; Cats; Cyclazocine; Dogs; Drug Interactions; Morphine Derivatives; Nalorphine; Naloxone; Naltrexone; Receptors, Opioid; Spinal Cord	1976
Methadone maintenance and narcotic blocking drugs. The International journal of the addictions, 1977, Volume: 12, Issue:7 Topics: Aftercare; Cyclazocine; Extinction, Psychological; Heroin Dependence; Hospitalization; Humans; Levallorphan; Methadone; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Psychotherapy; Receptors, Opioid	1977
A history of the development of narcotic antagonists for the treatment of narcotic addiction. NIDA research monograph, 1978, Issue:19 Topics: Animals; Cyclazocine; Drug Tolerance; Euphoria; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Substance-Related Disorders	1978
Conditioning effects of narcotics in humans. NIDA research monograph, 1978, Issue:18 Topics: Conditioning, Psychological; Cyclazocine; Drug Tolerance; Humans; Naltrexone; Narcotics; Substance Withdrawal Syndrome	1978
Acute effects of opiate agonists, partial agonists and antagonists on brain monoamines in the rat. Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 238, Issue:1 Topics: Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Cyclazocine; Dextrorphan; Female; Levallorphan; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Rats	1979
Prospects, problems, side effects, and safety of narcotic antagonists. The International journal of the addictions, 1977, Volume: 12, Issue:7 Topics: Cyclazocine; Delayed-Action Preparations; Humans; Naloxone; Naltrexone; Psychotherapy; Reinforcement, Social	1977
Evaluation of narcotic and narcotic antagonist interactions in primates. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration	1976
Pharmacotherapy of opiate addiction. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, May-22, Volume: 50, Issue:22 Topics: Adolescent; Adult; Cyclazocine; Female; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Naltrexone; Opium; Substance-Related Disorders; United States	1976
A behavioral paradigm for the evaluation of narcotic antagonists. Archives of general psychiatry, 1976, Volume: 33, Issue:3 Topics: Adult; Cyclazocine; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Research Design	1976
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3 Topics: Animals; Apomorphine; Cyclazocine; Cyclopropanes; Dextropropoxyphene; Dogs; Ethylketocyclazocine; Humans; Morphinans; Morphine; Morphine Dependence; Nalorphine; Naltrexone; Phenazocine; Spinal Cord	1976
The structure-action relationship and kinetics of some naloxone and naltrexone derivatives. Pharmacology, 1976, Volume: 14, Issue:1 Topics: Animals; Cyclazocine; Guinea Pigs; Ileum; Kinetics; Morphine; Morphine Derivatives; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Structure-Activity Relationship; Time Factors	1976
Inhibition of nucleic acid synthesis in the regenerating limb of salamanders treated with a DL-methadone or narcotic antagonists. Experimental neurology, 1976, Volume: 53, Issue:1 Topics: Animals; Cyclazocine; Depression, Chemical; DNA; Extremities; Methadone; Naltrexone; Narcotic Antagonists; Regeneration; RNA; Urodela	1976
Narcotic antagonists: naltrexone progress report: foreword. NIDA research monograph, 1976, Issue:9 Topics: Cyclazocine; Government Agencies; Heroin Dependence; Humans; Naltrexone; Narcotic Antagonists; Substance-Related Disorders; United States	1976
A unit for delivering multiple drug treatment and prevention services. Hospital & community psychiatry, 1975, Volume: 26, Issue:10 Topics: Adolescent; Adult; Community Mental Health Services; Connecticut; Cyclazocine; Heroin Dependence; Humans; Methadone; Naltrexone; Psychotherapy, Group; Substance-Related Disorders; Vocational Education	1975
Use of narcotic (opiate) antagonists. American family physician, 1976, Volume: 13, Issue:3 Topics: Cyclazocine; Humans; Naloxone; Naltrexone; Narcotic Antagonists	1976
Opioid agonist affinity in the guinea-pig ileum and mouse vas deferens. European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2 Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Methadone; Mice; Morphine; Morphine Derivatives; Naltrexone; Receptors, Opioid; Vas Deferens	1990
Enhanced sensitivity to behavioral effects of naltrexone in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Rats; Salivation	1990
Opioid- and phencyclidine-like discriminative effects of ditolylguanidine, a selective sigma ligand. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Generalization, Psychological; Guanidines; Haloperidol; Levorphanol; Male; Naltrexone; Narcotics; Phencyclidine; Rats; Receptors, Opioid; Receptors, sigma; Stereoisomerism	1989
Estimation of affinities and efficacies for kappa-receptor agonists in guinea-pig ileum. British journal of pharmacology, 1989, Volume: 96, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Binding, Competitive; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1989
Effects of kappa agonists and dexoxadrol on the acquisition of conditional discriminations in monkeys. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2 Topics: Analgesics; Animals; Benzomorphans; Conditioning, Psychological; Cyclazocine; Dioxolanes; Dioxoles; Discrimination Learning; Dose-Response Relationship, Drug; Erythrocebus patas; Ethylketocyclazocine; Female; Macaca fascicularis; Male; Naltrexone; Piperidines; Receptors, Opioid; Receptors, Opioid, kappa	1987
Roles of central and peripheral mu, delta and kappa opioid receptors in the mediation of gastric acid secretory effects in the rat. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Gastric Acid; Male; Morphine; Naltrexone; Pyrrolidines; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1988
Binaltorphimine-related bivalent ligands and their kappa opioid receptor antagonist selectivity. Journal of medicinal chemistry, 1988, Volume: 31, Issue:4 Topics: Animals; Chemical Phenomena; Chemistry; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Models, Molecular; Morphine; Muscle, Smooth; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship	1988
Only one pharmacophore is required for the kappa opioid antagonist selectivity of norbinaltorphimine. Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Animals; Chemical Phenomena; Chemistry; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Morphine; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship; Vas Deferens	1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1988
Estimation of opioid receptor agonist dissociation constants with beta-chlornaltrexamine, an irreversible ligand which also displays agonism. British journal of pharmacology, 1988, Volume: 95, Issue:1 Topics: Animals; Cyclazocine; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1988
Analeptic effect of opiate receptor agonists in rabbits. Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1 Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex	1985
An analysis of naltrexone and naloxone's possible agonistic actions in the dog. Drug and alcohol dependence, 1985, Volume: 15, Issue:4 Topics: Analgesics, Opioid; Animals; Cyclazocine; Dogs; Drug Synergism; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Reaction Time; Reflex; Reflex, Pupillary	1985
Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists. Life sciences, 1987, Mar-30, Volume: 40, Issue:13 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Chemical Phenomena; Chemistry; Cyclazocine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa	1987
TENA, a selective kappa opioid receptor antagonist. Life sciences, 1985, Feb-25, Volume: 36, Issue:8 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens	1985
Plasma corticosterone changes in response to central or peripheral administration of kappa and sigma opiate agonists. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3 Topics: Animals; Brain; Corticosterone; Cyclazocine; Ethylketocyclazocine; Humans; Hypothalamo-Hypophyseal System; Male; Morphine; Naloxone; Naltrexone; Opioid-Related Disorders; Phenazocine; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma	1985
N-(3-Fluoropropyl)-N-normetazocine, a potentially useful opiate antagonist for opiate receptor studies with positron emission tomography (PET). Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:3 Topics: Analgesics; Animals; Binding, Competitive; Brain; Cyclazocine; Guinea Pigs; In Vitro Techniques; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Tomography, Emission-Computed	1985
A radiolabeled-ligand-binding technique for the characterization of opioid receptors in the intact mouse vas deferens. Analytical biochemistry, 1985, Volume: 150, Issue:1 Topics: Animals; Binding, Competitive; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Mice; Morphine; Naltrexone; Radioligand Assay; Receptors, Opioid; Vas Deferens	1985
Phencyclidine-induced stereotyped behaviors after injection of ethylketocyclazocine, Mr 2266 and naltrexone in rats. Brain research, 1986, Jul-23, Volume: 378, Issue:2 Topics: Animals; Benzomorphans; Cyclazocine; Drug Interactions; Ethylketocyclazocine; Male; Motor Skills; Naltrexone; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereotyped Behavior	1986
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Buprenorphine; Cyclazocine; Ethylketocyclazocine; Fentanyl; Male; Naltrexone; Pain; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1986
Synthesis and opioid antagonist potencies of naltrexamine bivalent ligands with conformationally restricted spacers. Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Animals; Biological Assay; Chemical Phenomena; Chemistry; Cyclazocine; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; Molecular Conformation; Morphine; Muscle Contraction; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship	1986
Reversible and irreversible binding of beta-funaltrexamine to mu, delta and kappa opioid receptors in guinea pig brain membranes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2 Topics: Animals; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ethylmaleimide; Guinea Pigs; Kinetics; Male; Membranes; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride	1986
Selective proliferation of brain kappa opiate receptors in spontaneously hypertensive rats. Life sciences, 1986, Dec-29, Volume: 39, Issue:26 Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; Kinetics; Male; Naltrexone; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Opioid; Receptors, Opioid, kappa	1986
Unidirectional interaction between thyrotropin releasing hormone and opiates at the level of their brain receptors. General pharmacology, 1987, Volume: 18, Issue:1 Topics: Animals; Brain; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; Male; Naltrexone; Oligopeptides; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Thyrotropin-Releasing Hormone	1987
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu	1987
Nonequilibrium opioid antagonist activity of 6,14-dideoxynaltrexone derivatives. Journal of medicinal chemistry, 1987, Volume: 30, Issue:6 Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Structure-Activity Relationship	1987
Ethylketocyclazocine and bremazocine analgesia in neonatal rats. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:4 Topics: Analgesia; Analgesics; Animals; Animals, Newborn; Benzomorphans; Cyclazocine; Ethylketocyclazocine; Female; Male; Morphinans; Naltrexone; Narcotic Antagonists; Rats	1988
Dissociation of the opioid and nonopioid effects of cyclazocine. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1 Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Female; Hallucinogens; Morphine; Morphine Dependence; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Stereoisomerism	1988
Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and beta-funaltrexamine. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Endorphins; Ethylketocyclazocine; Female; Hot Temperature; Macaca mulatta; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Reaction Time; Tail	1987
Differential antagonism by naltrexone of the effects of opioids on a fixed-ratio discrimination in rats. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1 Topics: Animals; Conditioning, Operant; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Rats	1988
Phencyclidine-like discriminative stimulus effects of the stereoisomers of alpha- and beta-cyclazocine in rats. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: Animals; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Naltrexone; Phencyclidine; Rats; Rats, Inbred Strains; Stereoisomerism	1988
Effects of opioids and phencyclidine in combination with naltrexone on the acquisition and performance of response sequences in monkeys. Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:6 Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Erythrocebus patas; Female; Heroin; Methadone; Naloxone; Naltrexone; Narcotics; Phencyclidine; Reinforcement Schedule; Serial Learning	1985
Comparative antagonism by naltrexone and naloxone of mu, kappa, and delta agonists. European journal of pharmacology, 1984, Sep-03, Volume: 104, Issue:1-2 Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens	1984
Effects of full and partial kappa agonists and mu agonists on urine output of normally hydrated rats. Neuropeptides, 1984, Volume: 5, Issue:1-3 Topics: Animals; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Naltrexone; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1984
Studies on the nature and mechanism of the diuretic activity of the opioid analgesic ethylketocyclazocine. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3 Topics: Analgesics, Opioid; Animals; Body Water; Bufo marinus; Cyclazocine; Diuretics; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Naltrexone; Radioimmunoassay; Rats; Rats, Inbred Strains; Urinary Bladder; Vasopressins	1982
Antagonism of the discriminative effects of ethylketazocine, cyclazocine, and nalorphine in macaques. Psychopharmacology, 1984, Volume: 84, Issue:3 Topics: Analgesics, Opioid; Animals; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Macaca mulatta; Macaca nemestrina; Male; Nalorphine; Naltrexone; Narcotic Antagonists	1984
Opiate receptors: problems of definition and characterization. Advances in biochemical psychopharmacology, 1980, Volume: 21 Topics: Animals; Binding Sites; Brain; Caudate Nucleus; Cyclazocine; Endorphins; Enkephalins; Hippocampus; Humans; Morphine; Naloxone; Naltrexone; Receptors, Opioid	1980
Electroacupuncture analgesia is mediated by stereospecific opiate receptors and is reversed by antagonists of type I receptors. Life sciences, 1980, Feb-25, Volume: 26, Issue:8 Topics: Acupuncture Therapy; Analgesia; Animals; Cyclazocine; Diprenorphine; Electric Stimulation; Female; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Stereoisomerism; Time Factors	1980
Discriminative stimulus effects of prototype opiate receptor agonists in monkeys. European journal of pharmacology, 1980, Nov-07, Volume: 68, Issue:1 Topics: Animals; Apomorphine; Cyclazocine; Ethylketocyclazocine; Female; Generalization, Stimulus; Haloperidol; Male; Models, Biological; Morphine; Naltrexone; Phenazocine; Prejudice; Receptors, Opioid; Saimiri	1980
Emerging concepts concerning drug abuse. NIDA research monograph, 1980, Volume: 30 Topics: Adolescent; Adult; Animals; Cats; Conditioning, Psychological; Cyclazocine; Dogs; Euphoria; Guinea Pigs; Homeostasis; Humans; Models, Biological; Mood Disorders; Morphine Dependence; Naltrexone; Rats; Receptors, Opioid; Substance-Related Disorders	1980
Characterization of the kappa-subtype of the opiate receptor in the guinea-pig brain. British journal of pharmacology, 1981, Volume: 73, Issue:4 Topics: Animals; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Naloxone; Naltrexone; Narcotics; Phenoxybenzamine; Receptors, Opioid	1981
Stimulus properties of opioids with mixed agonist and antagonist activity. Federation proceedings, 1982, Volume: 41, Issue:7 Topics: Animals; Conditioning, Psychological; Cyclazocine; Dogs; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phencyclidine; Rats; Receptors, Opioid; Saimiri	1982
Interactions between narcotic agonists, partial agonists andd antagonists evaluated by punished an unpunished behavior in the rat. Psychopharmacology, 1982, Volume: 76, Issue:2 Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenazocine; Punishment; Rats; Rats, Inbred Strains; Receptors, Opioid	1982
Improved assays for the assessment of kappa- and delta-properties of opioid ligands. European journal of pharmacology, 1982, Nov-19, Volume: 85, Issue:2 Topics: Animals; Cyclazocine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Vas Deferens	1982
Relative involvement of receptor subtypes in opioid-induced inhibition of gastrointestinal transit in mice. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2 Topics: Animals; Charcoal; Cyclazocine; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Gastrointestinal Motility; Male; Mice; Morphine; Nalorphine; Naltrexone; Receptors, Opioid	1983
Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6 Topics: Animals; Buprenorphine; Cyclazocine; Diazepam; Diprenorphine; Drinking; Ethylketocyclazocine; Etorphine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Taste	1982
Narcotic discrimination in pigeons: antagonism by naltrexone. European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2 Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Meperidine; Morphine; Naloxone; Naltrexone; Narcotics	1984
Three-choice drug discrimination: phencyclidine-like stimulus effects of opioids. Psychopharmacology, 1983, Volume: 80, Issue:1 Topics: Animals; Choice Behavior; Cyclazocine; Dextroamphetamine; Discrimination, Psychological; Male; Naltrexone; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Secobarbital	1983
Phencyclidine-like discriminative stimulus properties of psychotomimetic opioids. Annals of the New York Academy of Sciences, 1982, Volume: 398 Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Generalization, Psychological; Generalization, Stimulus; Morphine; Naltrexone; Phencyclidine; Rats; Saimiri	1982
Phencyclidine-like discriminative stimulus properties of opioids in the squirrel monkey. Psychopharmacology, 1982, Volume: 77, Issue:4 Topics: Animals; Cyclazocine; Discrimination Learning; Female; Male; Naltrexone; Narcotics; Phenazocine; Phencyclidine; Saimiri; Time Factors	1982
Acquisition of brightness discrimination in the rat is impaired by opiates with psychotomimetic properties. Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:6 Topics: Animals; Avoidance Learning; Cyclazocine; Discrimination Learning; Male; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Phenazocine; Photic Stimulation; Psychotropic Drugs; Rats; Rats, Inbred F344	1983
Narcotic discrimination in pigeons. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1 Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity	1980
Pharmacological analysis of the discriminative stimulus characteristics of ethylketazocine in the rhesus monkey. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1 Topics: Animals; Cyclazocine; Dextrorphan; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Macaca mulatta; Naltrexone; Narcotic Antagonists; Narcotics; Phencyclidine; Prejudice; Stereoisomerism	1981
Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys. Federation proceedings, 1982, Volume: 41, Issue:2 Topics: Animals; Behavior, Animal; Conditioning, Operant; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Humans; Macaca; Macaca mulatta; Morphine; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Reinforcement, Psychology; Self Administration	1982
The relationship between the acute behavioral effects of narcotic antagonists and the narcotic-dependent state [proceedings]. Psychopharmacology bulletin, 1981, Volume: 17, Issue:1 Topics: Animals; Behavior, Animal; Columbidae; Cyclazocine; Humans; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists	1981
Three-choice drug discrimination in the rat: morphine, cyclazocine and saline. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2 Topics: Animals; Cyclazocine; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Generalization, Stimulus; Male; Morphine; Naltrexone; Pentazocine; Rats; Secobarbital; Sodium Chloride	1981
Clinical pharmacology of mixed agonist-antagonist drugs [proceedings]. Psychopharmacology bulletin, 1981, Volume: 17, Issue:1 Topics: Buprenorphine; Cyclazocine; Humans; Methadone; Morphinans; Morphine Dependence; Naltrexone	1981
Discriminative stimulus effects of cyclazocine in the rat. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:3 Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Generalization, Stimulus; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Prejudice; Psychotropic Drugs; Rats; Stimulation, Chemical; Time Factors	1980
Stereoselectivity of the stimulus effects of morphine and cyclazocine in the squirrel monkey. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:2 Topics: Animals; Avoidance Learning; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Generalization, Psychological; Morphine; Naltrexone; Prejudice; Saimiri; Stereoisomerism	1980
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats. Life sciences, 1997, Volume: 60, Issue:9 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes	1997
8-Aminocyclazocine analogues: synthesis and structure-activity relationships. Bioorganic & medicinal chemistry letters, 2000, Jan-17, Volume: 10, Issue:2 Topics: Analgesics; Animals; Benzeneacetamides; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Molecular Structure; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship	2000