Page last updated: 2024-09-04

cyc 682 and clofarabine

cyc 682 has been researched along with clofarabine in 5 studies

Compound Research Comparison

Studies (cyc 682)	Trials (cyc 682)	Recent Studies (post-2010) (cyc 682)	Studies (clofarabine)	Trials (clofarabine)	Recent Studies (post-2010) (clofarabine)
30	5	18	424	101	280

Protein Interaction Comparison

Protein	Taxonomy	cyc 682 (IC50)	clofarabine (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesterase	Homo sapiens (human)		3.12

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	4 (80.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Faderl, S; Gandhi, V; Kantarjian, HM	1
Czemerska, M; Grzybowska-Izydorczyk, O; Pluta, A; Robak, T; Szmigielska-Kapłon, A; Wierzbowska, A; Wolska, A	1
Baer, MR; Gojo, I	1
Burnett, AK; Hills, RK	1
Jabbour, E; Kadia, TM; Kantarjian, H	1

Reviews

3 review(s) available for cyc 682 and clofarabine

Article	Year
Potential role of novel nucleoside analogs in the treatment of acute myeloid leukemia. Current opinion in hematology, 2008, Volume: 15, Issue:2 Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Cytosine; Dioxolanes; Humans; Leukemia, Myeloid, Acute; Nucleosides	2008
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity. Current medicinal chemistry, 2011, Volume: 18, Issue:5 Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; Cytosine; Daunorubicin; Decitabine; Dioxolanes; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myeloid, Acute; Liposomes; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Valproic Acid; Vascular Endothelial Growth Factor Receptor-1	2011
Failure of hypomethylating agent-based therapy in myelodysplastic syndromes. Seminars in oncology, 2011, Volume: 38, Issue:5 Topics: Adenine Nucleotides; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Drug Resistance; Drug Substitution; Enzyme Inhibitors; Glutathione; Glycine; Humans; Myelodysplastic Syndromes; Stem Cell Transplantation; Sulfones; Treatment Failure	2011

Other Studies

2 other study(ies) available for cyc 682 and clofarabine

Article	Year
Novel agents for the treatment of acute myeloid leukemia in the older patient. Journal of the National Comprehensive Cancer Network : JNCCN, 2011, Volume: 9, Issue:3 Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quinolones; Thalidomide	2011
Applicability of a "Pick a Winner" trial design to acute myeloid leukemia. Blood, 2011, Sep-01, Volume: 118, Issue:9 Topics: Adenine Nucleotides; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Clinical Trials, Phase III as Topic; Clofarabine; Cost-Benefit Analysis; Cytarabine; Cytosine; Drug Discovery; Early Termination of Clinical Trials; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Oxides; Patient Selection; Quality-Adjusted Life Years; Quinolones; Randomized Controlled Trials as Topic; Research Design; Sample Size; Software Design; Treatment Outcome; United Kingdom	2011

Article

Year

Novel agents for the treatment of acute myeloid leukemia in the older patient.

Journal of the National Comprehensive Cancer Network : JNCCN, 2011, Volume: 9, Issue:3

Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quinolones; Thalidomide

2011

Applicability of a "Pick a Winner" trial design to acute myeloid leukemia.

Blood, 2011, Sep-01, Volume: 118, Issue:9

Topics: Adenine Nucleotides; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Clinical Trials, Phase III as Topic; Clofarabine; Cost-Benefit Analysis; Cytarabine; Cytosine; Drug Discovery; Early Termination of Clinical Trials; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Oxides; Patient Selection; Quality-Adjusted Life Years; Quinolones; Randomized Controlled Trials as Topic; Research Design; Sample Size; Software Design; Treatment Outcome; United Kingdom

2011