Page last updated: 2024-09-04

cyc 202 and simvastatin

cyc 202 has been researched along with simvastatin in 3 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(simvastatin)
Trials
(simvastatin)
Recent Studies (post-2010) (simvastatin)
97973938,4421,7303,630

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)simvastatin (IC50)
photoreceptor-specific nuclear receptorHomo sapiens (human)1.164
transactivating tegument protein VP16 [Human herpesvirus 1]Human alphaherpesvirus 1 (Herpes simplex virus type 1)4.426
Bile salt export pumpHomo sapiens (human)10
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.7843
ATP-dependent translocase ABCB1Homo sapiens (human)9.5
Insulin receptor Rattus norvegicus (Norway rat)0.0034
Prostaglandin G/H synthase 2Homo sapiens (human)0.0034
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0111
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.049
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)6.7

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

3 other study(ies) available for cyc 202 and simvastatin

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013