Compounds > cyc 202

Page last updated: 2024-09-04

cyc 202 and pyrazolanthrone

cyc 202 has been researched along with pyrazolanthrone in 10 studies

Compound Research Comparison

Studies (cyc 202)	Trials (cyc 202)	Recent Studies (post-2010) (cyc 202)	Studies (pyrazolanthrone)	Trials (pyrazolanthrone)	Recent Studies (post-2010) (pyrazolanthrone)
979	7	393	1,484	2	765

Protein Interaction Comparison

Protein	Taxonomy	cyc 202 (IC50)	pyrazolanthrone (IC50)
Chain A, Mitogen-activated protein kinase 10	Homo sapiens (human)		0.15
Chain A, Mitogen-activated protein kinase 10	Homo sapiens (human)		0.15
Chain A, Mitogen-activated protein kinase 10	Homo sapiens (human)		0.15
TPA: protein transporter TIM10	Saccharomyces cerevisiae S288C		20.2
TPA: protein transporter TIM23	Saccharomyces cerevisiae S288C		6.31
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)		0.72
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)		8
Dual specificity protein kinase TTK	Homo sapiens (human)		0.8987
Mitogen-activated protein kinase 8	Homo sapiens (human)		0.921
Mitogen-activated protein kinase 9	Homo sapiens (human)		1.0111
Tyrosine-protein kinase JAK3	Homo sapiens (human)		0.957
Mitogen-activated protein kinase 10	Homo sapiens (human)		1.4193
Mitogen-activated protein kinase 14	Homo sapiens (human)		0.15

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (70.00)	29.6817
2010's	2 (20.00)	24.3611
2020's	1 (10.00)	2.80

Authors

Authors	Studies
Atteridge, CE; Azimioara, MD; Benedetti, MG; Biggs, WH; Carter, TA; Ciceri, P; Edeen, PT; Fabian, MA; Floyd, M; Ford, JM; Galvin, M; Gerlach, JL; Grotzfeld, RM; Herrgard, S; Insko, DE; Insko, MA; Lai, AG; Lélias, JM; Lockhart, DJ; Mehta, SA; Milanov, ZV; Patel, HK; Treiber, DK; Velasco, AM; Wodicka, LM; Zarrinkar, PP	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N	1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Caballero, E; García-Cárceles, J; Gil, C; Martínez, A	1
Bravo, R; Bruna, A; Caelles, C; Camarasa, J; Camins, A; Canudas, AM; Escubedo, E; Jiménez, A; Jorda, EG; Pallàs, M; Pubill, D; Verdaguer, E	1
Muresan, V; Muresan, Z	1
Encheva, V; Heesom, KJ; Lach, R; Ray, S; Reddy, AB; Snijders, AP; Valekunja, UK	1

Reviews

1 review(s) available for cyc 202 and pyrazolanthrone

Article	Year
Kinase Inhibitors as Underexplored Antiviral Agents. Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2 Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses	2022

Other Studies

9 other study(ies) available for cyc 202 and pyrazolanthrone

Article	Year
A small molecule-kinase interaction map for clinical kinase inhibitors. Nature biotechnology, 2005, Volume: 23, Issue:3 Topics: Benzamides; Drug Design; Escherichia coli; Escherichia coli Proteins; Imatinib Mesylate; Microchemistry; Pharmaceutical Preparations; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Pyrimidines	2005
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
The selectivity of protein kinase inhibitors: a further update. The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3 Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera	2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51 Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis. Neuropharmacology, 2003, Volume: 45, Issue:5 Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Anthracenes; Anti-Bacterial Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Bromodeoxyuridine; Carrier Proteins; Caspase 3; Caspases; CDC2-CDC28 Kinases; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Chromatin; Colchicine; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flavonoids; Flow Cytometry; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; Microtubules; Minocycline; Mitogen-Activated Protein Kinase Kinases; Neurons; Neuroprotective Agents; Piperidines; Purines; Rats; Rats, Sprague-Dawley; Roscovitine; Time Factors; Tubulin	2003
c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-beta precursor protein. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-13, Volume: 25, Issue:15 Topics: Adaptor Proteins, Signal Transducing; Amyloid beta-Protein Precursor; Animals; Anisomycin; Anthracenes; Blotting, Western; Cell Line; Chlorocebus aethiops; Enzyme Inhibitors; Gene Expression Regulation; Growth Inhibitors; Humans; Immunohistochemistry; Immunoprecipitation; Mice; Mitogen-Activated Protein Kinase 10; Models, Biological; Neurites; Neurons; Phosphorylation; Protein Binding; Purines; RNA, Small Interfering; Roscovitine; Transfection	2005
Phenotypic proteomic profiling identifies a landscape of targets for circadian clock-modulating compounds. Life science alliance, 2019, Volume: 2, Issue:6 Topics: Adenine; Anthracenes; Cell Line, Tumor; Circadian Clocks; Circadian Rhythm; Drug Evaluation, Preclinical; Humans; Phenotype; Phosphorylation; Proteomics; Purines; Roscovitine; Signal Transduction; Transcription Factors	2019