Page last updated: 2024-09-04

cyc 202 and nsc 664704

cyc 202 has been researched along with nsc 664704 in 10 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(nsc 664704)
Trials
(nsc 664704)
Recent Studies (post-2010) (nsc 664704)
979739395050

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)nsc 664704 (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)0.8335
Cyclin-T1Homo sapiens (human)0.064
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.4
Tyrosine-protein kinase LckHomo sapiens (human)0.47
Cyclin-dependent kinase 1Homo sapiens (human)0.4
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 21.5
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.4
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)0.4243
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.064
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.4243
Cyclin-A2Homo sapiens (human)0.73
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.064
Cyclin-dependent kinase 2Homo sapiens (human)0.73
Mitogen-activated protein kinase 1Homo sapiens (human)9
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.064
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.023
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0657
Cyclin-dependent kinase 9Homo sapiens (human)0.064
Cyclin-A1Homo sapiens (human)0.73
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.6314
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.6314
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.4
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)0.4243

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (80.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benfield, PA; Boylan, JF; Sielecki, TM; Trainor, GL1
Bhattacharjee, AK; Ellis, W; Gerena, L; Geyer, JA; Kathcart, AK; Kyle, DE; Li, Z; Lopez-Sanchez, M; Nichols, DA; Prigge, ST; Terrell, J; Waters, NC; Woodard, CL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, X; Ding, HF; Lang, L; Liu, G; Sun, SY; Yan, C1
Moir, RD; Myre, MA; Tanzi, RE; Tesco, G; Wasco, W; Washicosky, K1
Chen, L; Li, X; Salinas, GD1

Reviews

1 review(s) available for cyc 202 and nsc 664704

ArticleYear
Cyclin-dependent kinase inhibitors: useful targets in cell cycle regulation.
    Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1

    Topics: Animals; Cell Cycle; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Models, Molecular

2000

Other Studies

9 other study(ies) available for cyc 202 and nsc 664704

ArticleYear
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.
    Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18

    Topics: Amino Acid Sequence; Animals; Antimalarials; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Molecular Sequence Data; Plasmodium falciparum; Structure-Activity Relationship

2003
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds.
    Chemistry & biology, 2015, Jul-23, Volume: 22, Issue:7

    Topics: CRISPR-Cas Systems; Gene Targeting; Genes; Genes, Reporter; Genetic Engineering; Humans; Internal Ribosome Entry Sites; Transcription, Genetic

2015
Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
    Cellular signalling, 2009, Volume: 21, Issue:4

    Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine

2009
Regulation of serotonin 1B receptor by glycogen synthase kinase-3.
    Molecular pharmacology, 2009, Volume: 76, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Benzazepines; Cell Line; CHO Cells; Cholera Toxin; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Glycogen Synthase Kinase 3; Humans; Indoles; Male; Maleimides; Mice; Mice, Inbred BALB C; Oxadiazoles; Oximes; Piperidines; Piperidones; Protein Kinase Inhibitors; Purines; Pyridines; Receptor, Serotonin, 5-HT1B; Roscovitine; Serotonin; Spiro Compounds

2009