Page last updated: 2024-09-04

cyc 202 and nocodazole

cyc 202 has been researched along with nocodazole in 10 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(nocodazole)
Trials
(nocodazole)
Recent Studies (post-2010) (nocodazole)
97973933,0780655

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)nocodazole (IC50)
Chain A, Glutathione-requiring prostaglandin D synthaseHomo sapiens (human)65
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)0.8334
Tyrosine-protein kinase ABL1Homo sapiens (human)0.64
Tubulin alpha-1A chainSus scrofa (pig)1.3775
Tubulin beta chainSus scrofa (pig)0.76
Tubulin beta-4A chainHomo sapiens (human)1.2975
Tubulin beta chainHomo sapiens (human)1.2975
Tubulin alpha-3C chainHomo sapiens (human)1.2975
Adenosine receptor A2aHomo sapiens (human)7.509
Tubulin alpha-1B chainHomo sapiens (human)1.2975
Tubulin alpha-4A chainHomo sapiens (human)1.2975
Tubulin beta-4B chainHomo sapiens (human)1.2975
Sodium-dependent dopamine transporter Homo sapiens (human)6.232
Tubulin beta-3 chainHomo sapiens (human)1.2975
Tubulin beta-2A chainHomo sapiens (human)1.2975
Tubulin beta-8 chainHomo sapiens (human)1.2975
Tubulin beta-2B chainBos taurus (cattle)2.3
Tubulin alpha-3E chainHomo sapiens (human)1.2975
Tubulin alpha-1A chainHomo sapiens (human)1.2975
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)2.3
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)2.3
Tubulin alpha-1C chainHomo sapiens (human)1.2975
Tubulin beta-6 chainHomo sapiens (human)1.2975
Tubulin beta-2B chainHomo sapiens (human)1.2975
Tubulin beta-1 chainHomo sapiens (human)1.2975

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Matsumoto, K; Nakamura, T; Sumi, T1
Aksenov, ND; Brichkina, AI; Neliudova, AM; Pospelova, TV; Rukhlova, MP1
Brice, A; Darios, F; Khondiker, ME; Muriel, MP; Ruberg, M1
Dangi, S; Shapiro, P1
McNeely, SC; States, JC; Taylor, BF1
Medema, RH; Ogink, J; te Riele, H; ter Riet, B; van Zon, W; Wolthuis, RM1
Hu, LY; Li, X; Wu, ZH; Xu, DQ1
Cibis, H; Hess, D; Klempnauer, KH; Werwein, E1

Other Studies

10 other study(ies) available for cyc 202 and nocodazole

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Mitosis-dependent phosphorylation and activation of LIM-kinase 1.
    Biochemical and biophysical research communications, 2002, Feb-01, Volume: 290, Issue:4

    Topics: Actins; Cell Cycle; Cyclin-Dependent Kinases; Cytoskeleton; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Lim Kinases; Mitosis; Nocodazole; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Purines; Roscovitine

2002
[Antiproliferative effect of bcl-2 gene does not concern the control of mitotic events].
    Tsitologiia, 2004, Volume: 46, Issue:3

    Topics: Adenovirus E1A Proteins; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Transformed; Culture Media; Cyclin-Dependent Kinases; Embryo, Mammalian; Enzyme Inhibitors; Fibroblasts; G1 Phase; G2 Phase; Genes, bcl-2; Genes, ras; Mitosis; Nocodazole; Polyploidy; Purines; Rats; Rats, Wistar; Roscovitine

2004
Neurotoxic calcium transfer from endoplasmic reticulum to mitochondria is regulated by cyclin-dependent kinase 5-dependent phosphorylation of tau.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-20, Volume: 25, Issue:16

    Topics: Analysis of Variance; Animals; Blotting, Western; Calcium; Cell Count; Cell Death; Cells, Cultured; Ceramides; Cloning, Molecular; Cyclin-Dependent Kinase 5; Cytochalasin D; Drug Interactions; Embryo, Mammalian; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation; Heterocyclic Compounds, 3-Ring; Immunohistochemistry; Male; Mesencephalon; Microscopy, Electron, Transmission; Mitochondria; Neurons; Nocodazole; Phosphorylation; Pregnancy; Purines; Rats; Rats, Wistar; Roscovitine; tau Proteins; Time Factors; Transfection; Tubulin

2005
Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis.
    The Journal of biological chemistry, 2005, Jul-01, Volume: 280, Issue:26

    Topics: CDC2 Protein Kinase; Cell Line, Tumor; Densitometry; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Phosphorylation; Protein Binding; Protein Biosynthesis; Proto-Oncogene Proteins c-raf; Purines; Roscovitine; Signal Transduction; SOS1 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Vinblastine

2005
Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent.
    Toxicology and applied pharmacology, 2008, Aug-15, Volume: 231, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenites; Blotting, Western; CDC2 Protein Kinase; Fluorescent Antibody Technique; Humans; Melanoma, Experimental; Mitosis; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Purines; RNA, Small Interfering; Roscovitine; Sodium Compounds

2008
The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit.
    The Journal of cell biology, 2010, Aug-23, Volume: 190, Issue:4

    Topics: Anaphase-Promoting Complex-Cyclosome; Animals; Carrier Proteins; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cdc20 Proteins; Cell Cycle Proteins; Cell Line; Cyclin A; Cyclin B1; Cyclin-Dependent Kinases; Humans; Mitosis; Neoplasm Proteins; Nocodazole; Phosphorylation; Prometaphase; Protein Binding; Protein Kinase Inhibitors; Purines; Recombinant Fusion Proteins; RNA Interference; Roscovitine; Securin; Tubulin Modulators; Ubiquitin; Ubiquitin-Protein Ligase Complexes

2010
A cell-based assay for screening spindle checkpoint inhibitors.
    Assay and drug development technologies, 2012, Volume: 10, Issue:4

    Topics: Antineoplastic Agents; Aurora Kinases; Blotting, Western; Cell Cycle; Cell Cycle Checkpoints; Cell Line; Coloring Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorescent Antibody Technique; HeLa Cells; High-Throughput Screening Assays; Humans; Mitotic Index; Nocodazole; Protein Serine-Threonine Kinases; Purines; Roscovitine; Spindle Apparatus; Tetrazolium Salts; Thiazoles

2012
Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization.
    Nucleic acids research, 2019, 01-10, Volume: 47, Issue:1

    Topics: Carcinogenesis; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinases; Gene Expression Regulation, Neoplastic; HeLa Cells; Hep G2 Cells; Humans; Mitosis; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Nocodazole; Peptidylprolyl Isomerase; Phosphorylation; Polo-Like Kinase 1; Protein Conformation; Protein Multimerization; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Roscovitine; Thymidine; Trans-Activators; Transcription, Genetic

2019