Compounds > cyc 202
Page last updated: 2024-09-04

cyc 202 and lactacystin

cyc 202 has been researched along with lactacystin in 4 studies

Compound Research Comparison

Studies
(cyc 202)		Trials
(cyc 202)		Recent Studies (post-2010)
(cyc 202)		Studies
(lactacystin)		Trials
(lactacystin)		Recent Studies (post-2010) (lactacystin)
97973939201155

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)lactacystin (IC50)
Proteasome subunit beta type-11Homo sapiens (human)0.259
Proteasome subunit alpha type-7Homo sapiens (human)0.259
Proteasome subunit beta type-1Homo sapiens (human)0.259
Proteasome subunit alpha type-1Homo sapiens (human)0.259
Proteasome subunit alpha type-2Homo sapiens (human)0.259
Proteasome subunit alpha type-3Homo sapiens (human)0.259
Proteasome subunit alpha type-4Homo sapiens (human)0.259
Proteasome subunit beta type-8Homo sapiens (human)0.259
Proteasome subunit beta type-9Homo sapiens (human)0.259
Proteasome subunit alpha type-5Homo sapiens (human)0.259
Proteasome subunit beta type-4Homo sapiens (human)0.259
Proteasome subunit beta type-6Homo sapiens (human)0.259
Proteasome subunit beta type-5Homo sapiens (human)1.2498
Proteasome subunit beta type-10Homo sapiens (human)0.259
Proteasome subunit beta type-3Homo sapiens (human)0.259
Proteasome subunit beta type-2Homo sapiens (human)1.7545
Proteasome subunit alpha type-6Homo sapiens (human)0.259
Splicing factor 3B subunit 3Homo sapiens (human)3.481
Proteasome subunit alpha-type 8Homo sapiens (human)0.259
Proteasome subunit beta type-7Homo sapiens (human)0.259

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Howley, PM; Kwon, YT; Patrick, GN; Tsai, LH; Zhou, P1
Kerokoski, P; Pirttilä, T; Salminen, A; Soininen, H; Suuronen, T1
Henfling, ME; Ramaekers, FC; Schutte, B1
Moir, RD; Myre, MA; Tanzi, RE; Tesco, G; Wasco, W; Washicosky, K1

Other Studies

4 other study(ies) available for cyc 202 and lactacystin

ArticleYear
p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.
    The Journal of biological chemistry, 1998, Sep-11, Volume: 273, Issue:37

    Topics: Acetylcysteine; Animals; Cells, Cultured; Cerebral Cortex; COS Cells; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Half-Life; Humans; Kinetics; Mammals; Mice; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Polymerase Chain Reaction; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Purines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Roscovitine; Sequence Deletion; Transfection; Ubiquitins

1998
Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35.
    Brain research. Molecular brain research, 2002, Oct-15, Volume: 106, Issue:1-2

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Animals, Newborn; Brain Chemistry; Calpain; Cells, Cultured; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Embryo, Mammalian; Enzyme Inhibitors; Hippocampus; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Okadaic Acid; Phosphorylation; Proteasome Endopeptidase Complex; Purines; Rats; Rats, Wistar; Roscovitine

2002
Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis.
    International journal of oncology, 2004, Volume: 25, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Lung Neoplasms; Membrane Potentials; Mitochondria; Proteasome Endopeptidase Complex; Purines; Roscovitine; Signal Transduction; Tumor Cells, Cultured

2004
Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
    Cellular signalling, 2009, Volume: 21, Issue:4

    Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine

2009