Page last updated: 2024-09-04

cyc 202 and fulvestrant

cyc 202 has been researched along with fulvestrant in 4 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(fulvestrant)
Trials
(fulvestrant)
Recent Studies (post-2010) (fulvestrant)
97973932,7122071,196

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)fulvestrant (IC50)
Estrogen receptorHomo sapiens (human)0.0061
Estrogen receptorRattus norvegicus (Norway rat)0.0059
Progesterone receptorHomo sapiens (human)0.0002
Steroid hormone receptor ERR1Homo sapiens (human)0.002
Bifunctional epoxide hydrolase 2Homo sapiens (human)0.006
Estrogen receptor betaHomo sapiens (human)0.0104
Bile acid receptorHomo sapiens (human)0.79
NAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)2.6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Musgrove, EA; Prall, OW; Rogan, EM; Sutherland, RL; Watts, CK1
Cowan, RG; Harman, RM; Quirk, SM1
Fernando, R; Foster, JS; Henley, D; Isbill, M; Wimalasena, J1

Other Studies

4 other study(ies) available for cyc 202 and fulvestrant

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry.
    Molecular and cellular biology, 1998, Volume: 18, Issue:8

    Topics: CDC2-CDC28 Kinases; Cell Cycle; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; G1 Phase; Humans; Molecular Mimicry; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Purines; Recombinant Fusion Proteins; Retinoblastoma-Like Protein p130; Roscovitine; S Phase; Tumor Cells, Cultured

1998
The susceptibility of granulosa cells to apoptosis is influenced by oestradiol and the cell cycle.
    The Journal of endocrinology, 2006, Volume: 189, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Bromodeoxyuridine; Cattle; Cell Proliferation; Cells, Cultured; Cyclins; Estradiol; Estrogen Antagonists; Fas Ligand Protein; Female; Flow Cytometry; Fulvestrant; G1 Phase; Granulosa Cells; Hydroxyurea; Immunohistochemistry; Interphase; Ki-67 Antigen; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Protein Kinase Inhibitors; Purines; Random Allocation; Roscovitine; S Phase; Tumor Necrosis Factors

2006
Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Breast Neoplasms; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA Fragmentation; Estradiol; Flow Cytometry; Fulvestrant; Humans; Hydroxyurea; Inhibitor of Apoptosis Proteins; JNK Mitogen-Activated Protein Kinases; Microtubule-Associated Proteins; Microtubules; Neoplasm Proteins; Paclitaxel; Purines; RNA, Small Interfering; Roscovitine; Spindle Apparatus; Survivin; Thymidine; Transfection

2007