Page last updated: 2024-09-04

cyc 202 and defactinib

cyc 202 has been researched along with defactinib in 2 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(defactinib)
Trials
(defactinib)
Recent Studies (post-2010) (defactinib)
979739341541

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)defactinib (IC50)
Tyrosine-protein kinase JAK2Homo sapiens (human)0.0282
High affinity nerve growth factor receptorHomo sapiens (human)0.0413
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.129
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.2732
Tyrosine-protein kinase JAK3Homo sapiens (human)0.1149
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)0.0753
Focal adhesion kinase 1Homo sapiens (human)0.0014
Protein-tyrosine kinase 2-betaHomo sapiens (human)0.0293
NT-3 growth factor receptorHomo sapiens (human)0.0578
BDNF/NT-3 growth factors receptorHomo sapiens (human)0.0549

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP1
Sakai, M; Yoshimura, R1

Other Studies

2 other study(ies) available for cyc 202 and defactinib

ArticleYear
The target landscape of clinical kinase drugs.
    Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays

2017
Mechanotransduction-Targeting Drugs Attenuate Stiffness-Induced Hepatic Stellate Cell Activation in Vitro.
    Biological & pharmaceutical bulletin, 2021, Mar-01, Volume: 44, Issue:3

    Topics: Actins; Adenosine Triphosphate; Animals; Benzamides; Cells, Cultured; Colchicine; Collagen Type I; Hepatic Stellate Cells; Imidazoles; Integrins; Male; Mechanotransduction, Cellular; Paclitaxel; Piperazines; Pyrazines; Quinoxalines; Rats, Sprague-Dawley; Roscovitine; Sulfonamides; Transforming Growth Factor beta; Tubulin Modulators

2021