cyc 202 has been researched along with cyclin d1 in 15 studies
| Studies (cyc 202) | Trials (cyc 202) | Recent Studies (post-2010) (cyc 202) | Studies (cyclin d1) | Trials (cyclin d1) | Recent Studies (post-2010) (cyclin d1) |
|---|---|---|---|---|---|
| 979 | 7 | 393 | 10,885 | 70 | 5,157 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Musgrove, EA; Prall, OW; Rogan, EM; Sutherland, RL; Watts, CK | 1 |
| Alessi, F; Meijer, L; Prosperi, E; Quarta, S; Riva, F; Rossi, L; Savio, M; Scovassi, AI; Stivala, LA | 1 |
| Chang, TH; Lee, HR; Senderowicz, AM; Szabo, E; Tebalt, MJ | 1 |
| Coverley, D; Jones, N; Krude, T; Laman, H; Laskey, R | 1 |
| Garrett, MD; Walton, MI; Whittaker, SR; Workman, P | 1 |
| Coombes, JD; Liddle, C; Mreich, E; Rangan, GK | 1 |
| André, P; Appert-Collin, A; Coupin, G; Gies, JP; Hugel, B; Levy, R; Lombard, Y; Niederhoffer, N; Poindron, P | 1 |
| Fleming, IN; Frame, S; Green, SR; Hogben, M; McClue, SJ | 1 |
| Moir, RD; Myre, MA; Tanzi, RE; Tesco, G; Wasco, W; Washicosky, K | 1 |
| Chiao, J; Cui, CY; Dong, D; Goh, BC; Green, S; Hsieh, WS; Lai, YF; Lee, SC; Loh, T; Mow, B; Peh, BK; Salto-Tellez, M; Soh, D; Soo, R; Soong, R; Wong, LS | 1 |
| Albrecht, JH; Anttila, CK; Berthet, C; Crary, GS; Goggin, MM; Hanse, EA; Kaldis, P; Kuriyama, R; Mullany, LK; Nelsen, CJ | 1 |
| Byrnes, KR; Faden, AI; Hanscom, M; Kabadi, SV; Loane, DJ; Stoica, BA | 1 |
| Nair, BC; Tekmal, RR; Vadlamudi, RK; Vallabhaneni, S | 1 |
| Beider, K; Josefsberg Ben-Yehoshua, L; Nagler, A; Ostrovsky, O; Peled, A; Samookh, M; Shimoni, A | 1 |
| Chao, AC; Chen, CH; Hou, BY; Wu, MH; Yang, DI | 1 |
15 other study(ies) available for cyc 202 and cyclin d1
| Article | Year |
|---|---|
c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry.
Topics: CDC2-CDC28 Kinases; Cell Cycle; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; G1 Phase; Humans; Molecular Mimicry; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Purines; Recombinant Fusion Proteins; Retinoblastoma-Like Protein p130; Roscovitine; S Phase; Tumor Cells, Cultured | 1998 |
The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity.
Topics: CDC2-CDC28 Kinases; Cell Line; Cyclin B; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA; Enzyme Inhibitors; Fibroblasts; G1 Phase; Humans; Kinetin; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Purines; Retinoblastoma Protein; Roscovitine | 1998 |
Induction of differentiation accompanies inhibition of Cdk2 in a non-small cell lung cancer cell line.
Topics: Carcinoma, Non-Small-Cell Lung; CDC2-CDC28 Kinases; Cell Differentiation; Cell Division; Cyclin D; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Flavonoids; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Proteins; Piperidines; Protein Serine-Threonine Kinases; Purines; Roscovitine; Signal Transduction; Transfection; Tumor Cells, Cultured | 1999 |
Viral cyclin-cyclin-dependent kinase 6 complexes initiate nuclear DNA replication.
Topics: 3T3 Cells; Animals; CDC2-CDC28 Kinases; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinases; Cyclins; DNA Replication; DNA-Binding Proteins; G1 Phase; Herpesviridae; Herpesvirus 8, Human; Humans; Mice; Microscopy, Fluorescence; Origin Recognition Complex; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Purines; Roscovitine; S Phase; Transfection; Tumor Cells, Cultured; Viral Proteins | 2001 |
The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Colonic Neoplasms; Cyclin D1; Cyclin-Dependent Kinases; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Purines; Retinoblastoma Protein; Roscovitine; Tumor Cells, Cultured | 2004 |
Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Division; Cyclin D1; Cyclin D3; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytoplasm; Epithelial Cells; Female; Growth Inhibitors; Immunosuppressive Agents; Kidney Cortex; Kidney Tubules; Monocytes; Proteinuria; Purines; Rats; Rats, Wistar; Roscovitine; Serum Albumin, Bovine; Sirolimus | 2005 |
Cyclin dependent kinase inhibitors prevent apoptosis of postmitotic mouse motoneurons.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cyclin D1; Cyclin E; Cyclin-Dependent Kinases; Flavonoids; Kinetin; Mice; Mitosis; Motor Neurons; Nerve Growth Factors; Piperidines; Protein Kinase Inhibitors; Purines; Roscovitine | 2006 |
Synergistic inhibition of ErbB signaling by combined treatment with seliciclib and ErbB-targeting agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cyclin D1; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Mice; Models, Biological; Mutation; Neoplasm Transplantation; Purines; Receptor, ErbB-2; Roscovitine | 2008 |
Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine | 2009 |
Pharmacodynamic effects of seliciclib, an orally administered cell cycle modulator, in undifferentiated nasopharyngeal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Apoptosis; Cell Cycle; Cyclin D1; DNA, Viral; Female; Gene Expression Profiling; Humans; Immunohistochemistry; Male; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-bcl-2; Purines; Roscovitine | 2009 |
Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo.
Topics: Animals; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Centrosome; Cyclin A; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Hepatocytes; Liver Regeneration; Mice; Mice, Inbred BALB C; Mice, Knockout; Purines; Roscovitine; Time Factors; Transfection | 2009 |
Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma.
Topics: Animals; Apoptosis; Behavior, Animal; Blotting, Western; Brain Injuries; Carrier Proteins; Cell Cycle; Cyclin A; Cyclin D1; Cyclin-Dependent Kinases; Disease Models, Animal; Immunohistochemistry; Maze Learning; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Motor Activity; Neurons; Neuroprotective Agents; Purines; Roscovitine; Time Factors | 2012 |
Roscovitine confers tumor suppressive effect on therapy-resistant breast tumor cells.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Co-Repressor Proteins; Cyclin D1; Cyclin-Dependent Kinase 2; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Mice; Mice, Nude; Nuclear Receptor Coactivator 3; Protein Kinase Inhibitors; Purines; Roscovitine; Transcription Factors; Xenograft Model Antitumor Assays | 2011 |
Characterization of cyclin E expression in multiple myeloma and its functional role in seliciclib-induced apoptotic cell death.
Topics: Apoptosis; Cell Line, Tumor; Cyclin D1; Cyclin E; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Gene Silencing; Genomic Instability; Humans; Multiple Myeloma; Oncogene Proteins; Piperidines; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Roscovitine | 2012 |
Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron.
Topics: Amyloid beta-Peptides; Animals; Cell Cycle; Cells, Cultured; Cerebral Cortex; Cyclin D1; Cyclin-Dependent Kinase 5; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitor of Differentiation Protein 1; Mitosis; Neurons; Peptide Fragments; Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Roscovitine | 2020 |