Page last updated: 2024-09-04

cyc 202 and bay 1000394

cyc 202 has been researched along with bay 1000394 in 4 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(bay 1000394)
Trials
(bay 1000394)
Recent Studies (post-2010) (bay 1000394)
979739319219

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)bay 1000394 (IC50)
NUAK family SNF1-like kinase 1Homo sapiens (human)0.01
Cyclin-T1Homo sapiens (human)0.005
Cyclin-dependent kinase 1Homo sapiens (human)0.0067
Cyclin-dependent kinase 4Homo sapiens (human)0.0101
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.007
G1/S-specific cyclin-D1Homo sapiens (human)0.011
G1/S-specific cyclin-E1Homo sapiens (human)0.0092
Cyclin-dependent kinase 2Homo sapiens (human)0.0086
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.163
Cyclin-dependent kinase 7Homo sapiens (human)0.021
Cyclin-dependent kinase 9Homo sapiens (human)0.005
Cyclin-HHomo sapiens (human)0.025
CDK-activating kinase assembly factor MAT1Homo sapiens (human)0.025
Cyclin-dependent kinase 3Homo sapiens (human)0.007
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.01
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.01

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Cheng, W; Kan, Q; Li, Y; Tian, X; Wang, S; Wei, H; Yang, Z1
Bian, J; Li, Z; Qin, Z; Tian, Y; Wang, J; Wu, T; Xu, C1
Duan, Y; Han, J; Hou, S; Liao, C; Wang, Q; Xie, Z; Yang, X1
Li, J; Liang, C; Liu, C; Qiang, T; Ren, X; Shi, Z; Tian, L; Xing, Y1

Reviews

4 review(s) available for cyc 202 and bay 1000394

ArticleYear
Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Animals; Crystallography, X-Ray; Cyclin-Dependent Kinases; Humans; Molecular Structure; Protein Binding; Protein Kinase Inhibitors

2019
Recent Developments in the Biology and Medicinal Chemistry of CDK9 Inhibitors: An Update.
    Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Cyclin-Dependent Kinase 9; Drug Development; Humans; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors; Protein Structure, Secondary

2020
Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts.
    Journal of medicinal chemistry, 2022, 05-12, Volume: 65, Issue:9

    Topics: Antineoplastic Agents; Cell Cycle; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Discovery; Humans; Neoplasms; Protein Kinase Inhibitors

2022
From Structure Modification to Drug Launch: A Systematic Review of the Ongoing Development of Cyclin-Dependent Kinase Inhibitors for Multiple Cancer Therapy.
    Journal of medicinal chemistry, 2022, 05-12, Volume: 65, Issue:9

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinases; Female; Humans; Pharmaceutical Preparations; Protein Kinase Inhibitors

2022