Compounds > cyc 202
Page last updated: 2024-09-04

cyc 202 and amitriptyline

cyc 202 has been researched along with amitriptyline in 3 studies

Compound Research Comparison

Studies
(cyc 202)		Trials
(cyc 202)		Recent Studies (post-2010)
(cyc 202)		Studies
(amitriptyline)		Trials
(amitriptyline)		Recent Studies (post-2010) (amitriptyline)
97973936,9351,3811,060

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)amitriptyline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.006
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.023
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.081
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0053
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.3
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.044
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.008
Alpha-2A adrenergic receptorHomo sapiens (human)0.1755
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.011
D(2) dopamine receptorHomo sapiens (human)1.009
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.044
Alpha-2B adrenergic receptorHomo sapiens (human)0.004
Alpha-2C adrenergic receptorHomo sapiens (human)0.0295
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.02
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.026
D(1A) dopamine receptorHomo sapiens (human)0.355
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.0324
Histamine H2 receptorHomo sapiens (human)0.73
Alpha-1D adrenergic receptorHomo sapiens (human)0.105
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.015
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.006
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.02
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.044
Sodium-dependent serotonin transporterHomo sapiens (human)0.2756
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.044
Histamine H1 receptorHomo sapiens (human)0.0048
D(3) dopamine receptorHomo sapiens (human)0.182
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.07
Histamine H2 receptorCavia porcellus (domestic guinea pig)0.66
5-hydroxytryptamine receptor 6Homo sapiens (human)0.14
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)7.2446
Sodium channel protein type 5 subunit alphaHomo sapiens (human)1.6
Sodium channel protein type 9 subunit alphaHomo sapiens (human)4
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.044
Sodium channel protein type 2 subunit alphaHomo sapiens (human)3.1
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.031
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.044

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1

Other Studies

3 other study(ies) available for cyc 202 and amitriptyline

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012