Page last updated: 2024-09-04

cyc 202 and alsterpaullone

cyc 202 has been researched along with alsterpaullone in 10 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(alsterpaullone)
Trials
(alsterpaullone)
Recent Studies (post-2010) (alsterpaullone)
979739380031

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)alsterpaullone (IC50)
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.004
Chain B, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.004
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.004
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.035
Cyclin-dependent kinase 1Homo sapiens (human)0.0321
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 21.5
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.035
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)0.0263
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.0263
Cyclin-A2Homo sapiens (human)0.015
Cyclin-dependent kinase 2Homo sapiens (human)0.015
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.0043
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0105
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.0608
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.0815
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.035
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)0.0263

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Benfield, PA; Boylan, JF; Sielecki, TM; Trainor, GL1
Bhattacharjee, AK; Ellis, W; Gerena, L; Geyer, JA; Kathcart, AK; Kyle, DE; Li, Z; Lopez-Sanchez, M; Nichols, DA; Prigge, ST; Terrell, J; Waters, NC; Woodard, CL1
Akula, N; Pattabiraman, N; Sridhar, J1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Baek, NI; Cho, JG; Jeon, YJ; Kim, GS; Lee, DY; Natarajan, S; Park, JH; Shrestha, S; Yang, DC; Yeon, SW1
Bharate, SB; Raghuvanshi, R1
Caballero, E; García-Cárceles, J; Gil, C; Martínez, A1
Belachew, S; Hans, G; Malgrange, B; Moonen, G; Nguyen, L; Rigo, JM; Rocher, V1

Reviews

3 review(s) available for cyc 202 and alsterpaullone

ArticleYear
Cyclin-dependent kinase inhibitors: useful targets in cell cycle regulation.
    Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1

    Topics: Animals; Cell Cycle; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Models, Molecular

2000
Selectivity and potency of cyclin-dependent kinase inhibitors.
    The AAPS journal, 2006, Mar-24, Volume: 8, Issue:1

    Topics: Animals; Binding Sites; Cyclin-Dependent Kinases; Humans; Protein Kinase Inhibitors; Signal Transduction

2006
Kinase Inhibitors as Underexplored Antiviral Agents.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses

2022

Other Studies

7 other study(ies) available for cyc 202 and alsterpaullone

ArticleYear
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.
    Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18

    Topics: Amino Acid Sequence; Animals; Antimalarials; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Molecular Sequence Data; Plasmodium falciparum; Structure-Activity Relationship

2003
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Potential neuroprotective flavonoid-based inhibitors of CDK5/p25 from Rhus parviflora.
    Bioorganic & medicinal chemistry letters, 2013, Sep-15, Volume: 23, Issue:18

    Topics: Cyclin-Dependent Kinase 5; Flavonoids; Humans; Models, Molecular; Molecular Structure; Nerve Tissue Proteins; Neuroprotective Agents; Rhus

2013
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022
Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2003, Volume: 21, Issue:6

    Topics: Animals; Animals, Newborn; Apoptosis; Benzazepines; Cell Differentiation; Cell Division; Cells, Cultured; Cerebral Cortex; Cyclin-Dependent Kinases; Enzyme Activation; Indoles; Oligodendroglia; Purines; Rats; Roscovitine

2003