cyc 202 has been researched along with 7-hydroxystaurosporine in 4 studies
| Studies (cyc 202) | Trials (cyc 202) | Recent Studies (post-2010) (cyc 202) | Studies (7-hydroxystaurosporine) | Trials (7-hydroxystaurosporine) | Recent Studies (post-2010) (7-hydroxystaurosporine) |
|---|---|---|---|---|---|
| 979 | 7 | 393 | 322 | 20 | 51 |
| Protein | Taxonomy | cyc 202 (IC50) | 7-hydroxystaurosporine (IC50) |
|---|---|---|---|
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | 0.0099 | |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alemany, C; Ciudad, CJ; Noé, V; Peñuelas, S | 1 |
| Bartek, J; Fugger, K; Hansen, LT; Helleday, T; Johansson, F; Lukas, J; Lundin, C; Sehested, M; Syljuåsen, RG; Sørensen, CS | 1 |
| Blagden, S; de Bono, J | 1 |
| Chen, XG; Zuo, MX | 1 |
2 review(s) available for cyc 202 and 7-hydroxystaurosporine
| Article | Year |
|---|---|
Drugging cell cycle kinases in cancer therapy.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Binding Sites; Cyclin-Dependent Kinases; Flavonoids; Humans; Neoplasms; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; Roscovitine; Staurosporine; Sulfonamides; Thiazoles | 2005 |
[Research on cyclin-dependent kinase inhibitors: state of the art and perspective].
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cyclin-Dependent Kinases; Cyclins; Flavonoids; Humans; Neoplasms; Piperidines; Purines; Roscovitine; Staurosporine | 2007 |
2 other study(ies) available for cyc 202 and 7-hydroxystaurosporine
| Article | Year |
|---|---|
The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors.
Topics: Animals; Blotting, Western; Cell Division; Cell Nucleus; CHO Cells; Cloning, Molecular; Cricetinae; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Flow Cytometry; HeLa Cells; Humans; Indoles; K562 Cells; Kinetin; Luciferases; Maleimides; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Synthesis Inhibitors; Purines; Retinoblastoma Protein; RNA, Messenger; Roscovitine; Sp1 Transcription Factor; Staurosporine; Tetrahydrofolate Dehydrogenase; Time Factors; Transcription, Genetic; Transfection | 2003 |
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
Topics: Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Proteins; Checkpoint Kinase 1; Checkpoint Kinase 2; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Replication; DNA-Binding Proteins; DNA, Single-Stranded; Histones; Humans; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Purines; Replication Protein A; RNA, Small Interfering; Roscovitine; Staurosporine; Tumor Suppressor Protein p53 | 2005 |