cyc 202 has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 15 studies
| Studies (cyc 202) | Trials (cyc 202) | Recent Studies (post-2010) (cyc 202) | Studies (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one) | Trials (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one) | Recent Studies (post-2010) (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one) |
|---|---|---|---|---|---|
| 979 | 7 | 393 | 4,823 | 5 | 1,810 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Cheng, X; Christ, J; Eisenbrand, G; Merz, KH; Muehlbeyer, S; Thommet, A; Vatter, S; Wölfl, S; Zeller, J | 1 |
| Bharate, SB; Raghuvanshi, R | 1 |
| Caballero, E; García-Cárceles, J; Gil, C; Martínez, A | 1 |
| Edamatsu, H; Gau, CL; Guo, L; Nemoto, T; Tamanoi, F | 1 |
| Conrad, D; Dai, Y; Dent, P; Grant, S; Krystal, G; Rahmani, M; Yu, C | 1 |
| Chen, L; Chen, Z; Cheng, JQ; Ren, Y; Reuther, GW; Wang, HG; Woods, NT; Wu, J | 1 |
| Campenot, RB; Carter, JM; Demizieux, L; Vance, DE; Vance, JE | 1 |
| Cheng, JQ; Chu, B; Djeu, J; Mohapatra, S; Pledger, WJ; Zhao, X | 1 |
| David-Pfeuty, T; Grierson, DS; Legraverend, M; Ludwig, O | 1 |
| Jin, X; Kong, X; Li, G; Liu, T; Wang, L | 1 |
| Kirschner, MW; Li, VC | 1 |
1 review(s) available for cyc 202 and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Kinase Inhibitors as Underexplored Antiviral Agents.
Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses | 2022 |
14 other study(ies) available for cyc 202 and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Screening Assays, Antitumor; Humans; Indoles; Oximes; Protein Kinase Inhibitors; Receptor, IGF Type 1; Signal Transduction; Solubility; Structure-Activity Relationship | 2017 |
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases | 2022 |
Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines.
Topics: Alkyl and Aryl Transferases; Apoptosis; Benzazepines; Caspases; Cell Line; Chromones; Cyclin-Dependent Kinases; Cytochrome c Group; Cytosol; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Farnesyltranstransferase; HL-60 Cells; Humans; Kinetin; Mitochondria; Morpholines; Phosphorylation; Purines; Retinoblastoma Protein; Roscovitine | 2000 |
The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
Topics: 2-Aminopurine; Antineoplastic Agents; Apoptosis; Chromones; Cyclin-Dependent Kinases; Drug Synergism; Enzyme Inhibitors; Flavonoids; Humans; Leukemia; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purines; Roscovitine; Tumor Cells, Cultured | 2003 |
Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL.
Topics: Amino Acid Substitution; Apoptosis; bcl-X Protein; Benzopyrans; Cell Line; Cell Survival; Chlorpropamide; Chromones; Down-Regulation; Elafin; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Mutation, Missense; Myeloid Cell Leukemia Sequence 1 Protein; Myeloid Progenitor Cells; Neoplasm Proteins; Nitriles; Oncogene Protein p21(ras); Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Purines; Roscovitine; Up-Regulation | 2007 |
Phosphatidylcholine biosynthesis via CTP:phosphocholine cytidylyltransferase 2 facilitates neurite outgrowth and branching.
Topics: Animals; Axons; Cell Differentiation; Cells, Cultured; Choline-Phosphate Cytidylyltransferase; Chromones; Cyclin-Dependent Kinase 5; Immunoprecipitation; Microscopy, Phase-Contrast; Morpholines; Neurites; Neurons; PC12 Cells; Phosphatidylcholines; Phospholipids; Phosphorylation; Proto-Oncogene Proteins c-akt; Purines; Rats; Retinal Ganglion Cells; Roscovitine | 2008 |
Apoptosis of metastatic prostate cancer cells by a combination of cyclin-dependent kinase and AKT inhibitors.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Caspase 9; Cell Line, Tumor; Chlorpropamide; Chromones; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinases; Dichlororibofuranosylbenzimidazole; DNA; Drug Synergism; Humans; Male; Membrane Proteins; Mitochondria; Morpholines; Nucleic Acid Synthesis Inhibitors; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purines; RNA, Small Interfering; Roscovitine; X-Linked Inhibitor of Apoptosis Protein | 2009 |
Targeting the cell cycle and the PI3K pathway: a possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Survival; Chromones; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; HeLa Cells; Humans; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Molecular Structure; Morpholines; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Purines; Roscovitine; Signal Transduction; Structure-Activity Relationship; Time Factors; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins | 2010 |
Hippocampal glycogen synthase kinase 3β is critical for the antidepressant effect of cyclin-dependent kinase 5 inhibitor in rats.
Topics: 4-Butyrolactone; Animals; Antidepressive Agents; Chromones; Cyclin-Dependent Kinase 5; Depression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Helplessness, Learned; Hippocampus; Indoles; Male; Maleimides; Morpholines; Purines; Rats; Rats, Sprague-Dawley; Roscovitine | 2014 |
Molecular ties between the cell cycle and differentiation in embryonic stem cells.
Topics: Animals; Cell Cycle; Cell Differentiation; Chromones; Cloning, Molecular; DNA Primers; Embryonic Development; Embryonic Stem Cells; Flavonoids; MAP Kinase Kinase 1; Mice; Microarray Analysis; Morpholines; Muscle, Skeletal; Phosphoinositide-3 Kinase Inhibitors; Plasmids; Purines; Reverse Transcriptase Polymerase Chain Reaction; Roscovitine | 2014 |