cyanopindolol has been researched along with pindolol in 233 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (23.61) | 18.7374 |
| 1990's | 125 (53.65) | 18.2507 |
| 2000's | 41 (17.60) | 29.6817 |
| 2010's | 12 (5.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crino, PB; Jensen, EL; Vogt, BA | 1 |
| Kompa, AR; Molenaar, P; Pak, HS; Roberts, SJ; Summers, RJ | 1 |
| Tran, VT | 1 |
| Liggett, SB | 1 |
| Fraeyman, N; Van de Velde, E; Van Ermen, A; Vanscheeuwijck, P | 1 |
| Danilo, P; Malfatto, G; Rosen, MR; Rosen, TS; Steinberg, SF | 1 |
| McNeel, RL; Mersmann, HJ | 1 |
| Houslay, MD; Milligan, G; Strassheim, D | 1 |
| Chiyotani, A; Kondo, M; Konno, K; Takeuchi, S; Tamaoki, J; Yamauchi, F | 1 |
| Molenaar, P; Russell, FD; Summers, RJ | 1 |
| Esbenshade, TA; Granneman, JG; Han, C; Minneman, KP; Theroux, TL | 1 |
| Gustafson, I; Westerberg, EJ; Wieloch, T | 1 |
| Hamblin, MW; McGuffin, RW; Metcalf, MA | 1 |
| Grignaschi, G; Samanin, R | 1 |
| Cornett, LE; Rossby, SP | 1 |
| Anlar, B; Arnason, BG; Karaszewski, JW; Kim, WC; Reder, AT | 1 |
| Emmerich, B; Göhly, U; Haen, E; Hallek, M; Kamp, T; Remien, J | 1 |
| Amenta, F; Coppola, L; Ferrante, F; Forlani, A; Gallo, P; Monopoli, A; Napoleone, P | 1 |
| Crino, PB; Vogt, BA; Volicer, L | 1 |
| Doran, AR; Fregeau, DR; Gietzen, DW; Goodman, TA; Graf, K; Maddock, RJ; Magliozzi, JR; Weiler, PG | 1 |
| Anderson, DR; Ferrari-Dileo, G; Feuer, WJ; Grajewski, AL | 1 |
| MacDonald, A; McLaughlin, DP | 1 |
| Lafontan, M; Langin, D; Portillo, MP; Saulnier-Blache, JS | 1 |
| Kim, YS; Molenaar, P; Sainz, RD; Summers, RJ | 1 |
| Otto, J; Pohl, A; Urbanek, R | 1 |
| Molenaar, P; Russell, FD; Shimada, T; Summers, RJ | 1 |
| Kostowski, W; Pałejko, W; Płaźnik, A; Stefański, R | 1 |
| Ulrichsen, J | 1 |
| Aihara, K; Homma, I; Inazu, M; Inoue, K; Sakai, Y | 1 |
| De Felipe, MC; Del Río, J; Montero, D | 1 |
| Druse, MJ; Kuo, A; Tajuddin, N | 1 |
| Atgie, C; Carpene, C; Lafontan, M; Quideau, N; Saulnier-Blache, JS | 1 |
| Jeffery, PK; Sharma, RK | 1 |
| Fraeyman, N; Van de Velde, E; Vanscheeuwijck, P | 1 |
| Fortin, TL; Sundaresan, PR | 1 |
| Moudry, R; Porzig, H | 1 |
| Carpéné, C; Dauzats, M; Lafontan, M; Larrouy, D; Quideau, N; Saulnier-Blache, JS | 1 |
| Lerea, LS; McCarthy, KD | 1 |
| Borst, SE; Conolly, ME; Hui, KK | 1 |
| Kahle, G; Kaulen, P; Wollensak, J | 1 |
| Folléa, N; Fortier, MA; Labrie, F; Marchetti, B; Pelletier, G; Poyet, P | 1 |
| Labrie, F; Marchetti, B | 1 |
| Caron, MG; Hausdorff, WP; Hnatowich, M; Lefkowitz, RJ; O'Dowd, BF | 1 |
| Arnason, BG; Brown, M; Karaszewski, JW; Maselli, R; Reder, AT | 1 |
| el-Yassir, N; Fleetwood-Walker, SM | 1 |
| Borton, M; Docherty, JR | 1 |
| Goldie, RG; Passarelli, MC; Rigby, PJ; Self, GJ | 1 |
| Cooper, SJ; Neill, JC | 1 |
| Ariani, K; Ciaranello, RD; Hamblin, MW; Stratford, CA; Tan, GL | 1 |
| Dalpé, M; de Montigny, C; Lal, S; Martial, J; Olivier, A; Quirion, R | 1 |
| De Boer, SF; Nijkamp, FP; Thijssen, JH; Van Heuven-Nolsen, D; Van Oosterhout, AJ | 1 |
| Grogan, DM; Hatjis, CG; Koritnik, DR | 2 |
| Davis, JN; Nishino, K | 1 |
| Hintze, TH; Homcy, CJ; Nejima, J; Susanni, EE; Uemura, N; Vatner, DE; Vatner, SF | 1 |
| Henricks, PA; Nijkamp, FP; van Esch, B; van Oosterhout, AJ | 1 |
| Murphree, SS; Saffitz, JE | 1 |
| Booze, RM; Crisostomo, EA; Davis, JN | 2 |
| Korichneva, IL; Krasnikova, TL; Radiukhin, VA | 1 |
| Cardone, F; Cignarelli, M; Corso, M; De Pergola, G; Di Paolo, S; Garruti, G; Giorgino, R; Nardelli, G | 1 |
| Folléa, N; Labrie, F; Marchetti, B; Pelletier, G; Plante, M; Poyet, P; Spinola, PG | 1 |
| Daniel, EE; Kostka, P; Kwan, CY; Niles, LP; Sipos, SN | 1 |
| Grogan, DM; Hatjis, CG | 1 |
| Hamon, M; Ruiz, G; Vergé, D | 1 |
| Chung, MK; Gulick, T; Lange, LG; Pieper, SJ; Schreiner, GF | 1 |
| Davis, JM; Janicak, PG; Pandey, GN | 1 |
| Caron, MG; Daniel, K; Kobilka, BK; Kobilka, TS; Lefkowitz, RJ; Regan, JW | 1 |
| Crews, A; Hatjis, CG | 1 |
| Caron, MG; Collins, S; French, FS; Lefkowitz, RJ; Quarmby, VE | 1 |
| Levitzki, A; Marbach, I | 1 |
| Klaassen, AB; Rodrigues de Miranda, JF; van den Broek, P; van Ginneken, CA; van Megen, YJ; van Ratingen, CJ | 1 |
| Pelletier, G; Tolszczuk, M | 1 |
| Cooke, R; Ellis, PM; McIntosh, CJ; Stowell, LI | 1 |
| Butina, D; Coates, LH; Connor, HE; Feniuk, W; Humphrey, PP; Oxford, AW; Perren, MJ | 1 |
| Davis, EA; Hall, S; Handberg, GM; Molenaar, P; Pennefather, JN; Summers, RJ | 1 |
| Göthert, M; Hillenbrand, K; Schlicker, E | 1 |
| Malta, E; Molenaar, P | 1 |
| Crooke, ST; Gotlib, L; Minnich, MD; Shorr, RG; Strohsacker, MW; Varrichio, A | 1 |
| Gagne, B; Labrie, F; Lavoie, M; Poyet, P | 1 |
| Edwards, E; Whitaker-Azmitia, PM | 1 |
| Kusiak, JW; Pitha, J | 1 |
| Lew, R; Summers, RJ | 2 |
| Lange, F; Lange, J; Morin, D; Tillement, JP; Zini, R | 1 |
| Levitzki, A; Marbach, I; Shiloach, J | 1 |
| Earley, KJ; Gunasegaram, S; Tenner, TE | 1 |
| Bittera, I; Eck, E; Falkay, G; Gyurkovits, K; Koltai, M | 1 |
| Deighton, N; Elfellah, MS; Reid, JL | 1 |
| Curzon, G; Kennett, GA | 1 |
| Engel, G; Göthert, M; Hillenbrand, K; Hoyer, D; Schlicker, E | 1 |
| Feuerstein, TJ; Hertting, G; Lupp, A | 1 |
| Houston, DS; Vanhoutte, PM | 1 |
| el-Yassir, N; Fleetwood-Walker, SM; Mitchell, R | 1 |
| Caron, MG; Dickinson, KE; Leeb-Lundberg, LM; Lefkowitz, RJ; Strasser, RH | 1 |
| Crooke, ST; Heckman, GD; Nambi, P; Schmidt, DB; Stassen, FL; Whitman, MH | 1 |
| Lipe, S; Summers, RJ | 1 |
| Molenaar, P; Summers, RJ | 1 |
| Canale, E; Molenaar, P; Summers, RJ | 1 |
| Beld, AJ; Hermanussen, MW; Lammers, JW; Rodrigues de Miranda, JF; van Ginneken, CA; van Koppen, CJ; Verrijp, KN | 1 |
| Candelore, MR; Dixon, RA; Rands, E; Strader, CD | 1 |
| Maura, G; Raiteri, M; Ulivi, M | 1 |
| Classen, K; Fink, K; Göthert, M; Schlicker, E | 1 |
| Björntorp, P; Edén, S; Xu, X; Yang, S | 1 |
| Blankesteijn, WM; de Pont, JJ; Graafsma, SJ; Thien, T; Willems, PH | 1 |
| Bejarano, P; Green, SA; Hall, IP; Liggett, SB; Turki, J | 1 |
| Kim, KR; Maia, AL; Raasmaja, A; Rubio, A; Silva, JE | 1 |
| Bax, WA; Bos, E; Renzenbrink, GJ; Saxena, PR; Thijssen, EJ; Van Heuven-Nolsen, D | 1 |
| Aryana, A; Emala, CW; Hirshman, CA; Levine, MA; Margolick, JB | 1 |
| Grignaschi, G; Samanin, R; Sironi, F | 1 |
| Aller, MI; Candelas, MA; Fernández-López, A; Pazos, A; Revilla, V; Soria, C | 1 |
| Chaudhry, A; Cohen, ML; Cushing, DJ; Granneman, JG; Palkowitz, AD; Schenck, KW | 1 |
| Breslow, MJ; Clarkson, K; Tobin, JR | 1 |
| Anciones, B; Berciano, J; Grijalba, B; Pascual, J; Pazos, A | 1 |
| Haugen, AH; Opstad, PK; Skrede, KK; Wiik, P | 1 |
| Cazaux, C; Cremaschi, GA; Miguel, S; Sterin-Borda, L | 1 |
| Minneman, KP; Zhong, H | 1 |
| Hirsch, DJ; Morgunov, NS; You, YD | 1 |
| Kahle, G; Kaulen, P; Scherer, V; Wollensak, J | 1 |
| Elnatan, J; Molenaar, P; Rosenfeldt, FL; Summers, RJ | 1 |
| Chojnacka-Wójcik, E; Filip, M; Przegaliński, E; Tatarczyńska, E | 1 |
| Kompa, AR; Molenaar, P; Russell, FD; Summers, RJ | 1 |
| Esposito, E; Pagannone, S; Prisco, S | 1 |
| Amara, DA; Buhot, MC; Dierich, A; Hen, R; LeMeur, M; Ramboz, S; Saudou, F; Segu, L | 1 |
| Chiyotani, A; Konno, K; Takeuchi, S; Tamaoki, J; Yamauchi, F; Yamawaki, I | 1 |
| Dombrowski, MP; Gauvin, JM; Hayashi, RH; Hurd, WW | 1 |
| Birnbaumer, L; Kaumann, AJ; Levy, FO; Zhu, X | 1 |
| Clark, CJ; Connell, JM; Milligan, G | 1 |
| Futuro-Neto, HA; Pires, JG; Ramage, AG; Silva, SR | 1 |
| Craig, DA; Martin, GR | 1 |
| Ikegaya, T; Kaneko, M; Kobayashi, A; Nishiyama, T; Yamazaki, N | 1 |
| Grignaschi, G; Mantelli, B; Samanin, R | 1 |
| Chojnacka-Wójcik, E; Przegalinski, E; Tatarczyńska, E | 1 |
| Molenaar, P; Sarsero, D | 1 |
| Molenaar, P; Roberts, SJ; Russell, FD; Summers, RJ | 1 |
| Crick, H; Manuel, NA; Wallis, DI | 1 |
| Oriowo, MA | 1 |
| Hoey, A; Jackson, C; Pegg, G; Sillence, M | 1 |
| Browning, RA; Dailey, JW; Jobe, PC; Statnick, MA | 1 |
| Esbenshade, TA; Guerrero, SW; Minneman, KP; Zhong, H | 1 |
| Calvo, JR; Caraballo, MI; Garcia-Macias, JF; Guerrero, JM; Harmouch, A; Molinero, P; Osuna, C; Pozo, D; Rafii-el-Idrissi, M | 1 |
| Brown, AM; Kaumann, AJ; Lynham, JA | 1 |
| Cui, Y; Iwase, M; Kalthof, B; Sato, N; Shen, YT; Uechi, M; Vatner, DE; Vatner, SF | 1 |
| Fillion, G; Fillion, MP; Massot, O; Prudhomme, N; Rousselle, JC; Zifa, E | 1 |
| Abraini, JH; Kriem, B; Rostain, JC | 1 |
| Bouanani, NE; Crozatier, B; Su, JB; Xiong, L | 1 |
| Gabilondo, AM; Krasel, C; Lohse, MJ | 1 |
| Díaz-Laviada, I; Guillén, A; Haro, A; Nieto, JL | 1 |
| El Hadri, K; Fève, B; Pairault, J | 1 |
| Malinowska, B; Schlicker, E | 2 |
| Kaumann, AJ; Molenaar, P | 1 |
| Bolofo, ML; Giles, H; Lansdell, SJ; Martin, GR; Wilson, HL | 1 |
| Björntorp, P; Edén, S; Liu, X; Yang, S | 1 |
| Hoey, AJ; Jackson, CM; Pegg, GG; Sillence, MN | 1 |
| Herman, CA; Luczy, G; Uhlén, S; Wikberg, JE | 1 |
| Feuerstein, TJ; Gleichauf, O; Landwehrmeyer, GB | 1 |
| Houston, G; Kelly, J | 1 |
| Dutta, PK; Eraundorfer, P; Patil, PN | 1 |
| Lohse, MJ; Oesterhelt, D; Söhlemann, P; Soppa, J | 1 |
| Bado, A; Laigneau, JP; Levasseur, S; Lewin, MJ; Moizo, L; Reyl-Desmars, F | 1 |
| Ouyang, A; Yu, O | 1 |
| Bernstein, D; Chruscinski, A; Desai, KH; Kobilka, BK; Rohrer, DK; Schauble, E | 1 |
| Gjerstad, J; Hole, K; Tjølsen, A | 1 |
| Audigier, Y; Caput, D; Devic, E; Paquereau, L; Steinberg, R | 1 |
| Conti, P; Dallanoce, C; De Amici, M; De Micheli, C; Klotz, KN | 1 |
| Cohen-Tannoudji, J; Coudouel, N; Lécrivain, JL; Legrand, C; Maltier, JP; Robin, MT | 1 |
| Atlan, G; Collet, F; Féve, B; Frisdal, E; Pavoine, C; Pecker, F | 1 |
| Isono, K; Nagai, A; Tagaya, E; Tamaoki, J | 1 |
| Branchek, TA; Zgombick, JM | 1 |
| Centurión, D; Rabelo, G; Sánchez-López, A; Villalón, CM | 1 |
| Dhalla, NS; Elimban, V; Persad, S; Siddiqui, F | 1 |
| Baranski, TJ; Bourne, HR; Iiri, T; Lichtarge, O; Meng, EC; Nissenson, RA; Sheikh, SP; Vilardarga, JP | 1 |
| Arnold, PB; Cardenas, CG; Cardenas, LM; Mar, LP; Scroggs, RS; Surmeier, DJ; Vysokanov, AV | 1 |
| Bouzeghrane, F; Fagette, S; Gallo-Bona, N; Gauquelin-Koch, G; Gharib, C; Somody, L | 1 |
| Guerrero, SW; Minneman, KP | 1 |
| Daws, LC; Frazer, A; Gerhardt, GA | 1 |
| MacDonald, A; Watt, K | 1 |
| Cherian, A; Mustafa, SM; Oriowo, MA; Yousif, M | 1 |
| Dorn, GW; Liggett, SB; Tepe, NM; Wu, G; Yatani, A | 1 |
| Boege, F; Haase, W; Hampe, W; Michel, H; Reiländer, H; Voss, RH | 1 |
| Brawley, L; MacDonald, A; Shaw, AM | 2 |
| Brink, CB; Neubig, RR; Wade, SM | 1 |
| Töneke, K | 1 |
| Ando, M; Ando, Y; Nakamura, M; Obayashi, K; Suga, M; Terazaki, H; Uchino, M; Yamashita, T | 1 |
| Daws, LC; Frazer, A; Gerhardt, GA; Gould, GG; Teicher, SD | 1 |
| Ammer, H; Schulz, R | 1 |
| Evans, BA; Hutchinson, DS; Summers, RJ | 1 |
| Engelhardt, S; Hein, L; Kaumann, AJ; Lohse, M; Molenaar, P | 1 |
| Yan, QS; Yan, SE | 2 |
| Ase, AR; Descarries, L; Hen, R; Reader, TA; Riad, M | 1 |
| Aubert, N; Burlet, C; Devaux, Y; Mertes, PM; Seguin, C; Siaghy, EM; Ungureanu-Longrois, D; Zannad, F | 1 |
| Green, SA; Liggett, SB; Rathz, DA; Schuster, AJ | 1 |
| Hussein, SM; Khan, I; Oriowo, M | 1 |
| Chi, J; Stephens, RL; Varanasi, S | 1 |
| Cremaschi, GA; Edgar, VA; Genaro, AM; Sterin-Borda, L | 1 |
| Möck, M; Schwarz, C; Thier, P | 1 |
| Hrupka, BJ; Langhans, W; von Meyenburg, C | 1 |
| Banks, ML; Cook, VJ; Mills, EM; Sprague, JE | 1 |
| Andrade, R; Béïque, JC; Chapin-Penick, EM; Mladenovic, L | 1 |
| Barakat, H; Christian, B; Davis, J; Hickner, R; McConnaughey, MM; Privette, J; Sheets, KA | 1 |
| Ishii, K; Karikomi, Y; Kubota, Y; Nakahara, T; Sakamoto, K | 1 |
| Brahmadevara, N; MacDonald, A; Shaw, AM | 1 |
| Jackman, GP; Louis, SN; Louis, WJ; Machida, CA; Nero, TL; Rezmann-Vitti, LA | 1 |
| Brown, MJ; O'Shaughnessy, KM; Sandilands, A; Yeo, G | 1 |
| Cremaschi, G; Fernández, MM; Fossati, CA; Goin, JC; Gorelik, G; Malchiodi, EL; Zwirner, NW | 1 |
| Desfontis, JC; Gauthier, C; Gautier, F; Gogny, M; Mallem, MY; Serpillon, S; Toumaniantz, G | 1 |
| Christopoulos, A; Evans, BA; Hutchinson, DS; Sato, M; Summers, RJ | 1 |
| Chandrasekhar, B; Fatinikun, T; Kadavil, EA; Khan, I; Omu, AE; Oriowo, MA | 1 |
| Desfontis, JC; Gogny, M; Holopherne, D; Le Coz, O; Mallem, Y; Reculeau, O | 1 |
| Desfontis, JC; Gogny, M; Le Coz, O; Mallem, MY; Reculeau, O | 1 |
| Kozłowska, H; Kwolek, G; Malinowska, B; Schlicker, E; Zakrzeska, A | 1 |
| Clark, RB; Dai, W; Friedman, J; Godines, V; Knoll, BJ; Millman, EE; Moore, RH; Tran, TM; Vaughan, DJ | 1 |
| Odagaki, Y; Toyoshima, R | 1 |
| Baranowska, M; Kozłowska, H; Kozłowski, M; Malinowska, B; Schlicker, E | 1 |
| Chan, YS; Chen, L; Yung, KK; Yung, WH | 1 |
| Baker, JG; Edwards, PC; Henderson, R; Leslie, AG; Moukhametzianov, R; Schertler, GF; Serrano-Vega, MJ; Tate, CG; Warne, T | 1 |
| Amour, J; Birenbaum, A; Heymes, C; Loyer, X; Michelet, P; Riou, B | 1 |
| Sabio, M; Topiol, S | 1 |
| Chess-Williams, R; Kay, LJ; Peachell, PT; Rostami-Hodjegan, A; Scola, AM; Suvarna, SK | 1 |
| Balaraman, GS; Bhattacharya, S; Vaidehi, N | 1 |
| Miller, JL; Tate, CG | 1 |
| Ribeiro, CA; Silva, SA | 1 |
| Bai, F; Cherezov, V; Gao, X; Han, GW; Huang, XP; Jiang, H; Jiang, Y; Katritch, V; Liu, W; Ma, J; McCorvy, JD; Melcher, K; Roth, BL; Stevens, RC; Vardy, E; Wacker, D; Wang, C; Wu, H; Xu, HE; Yang, H; Yang, L; Zhang, C; Zhou, XE | 1 |
| Daws, LC; Horton, RE; Montañez, S; Munn, JL; Owens, WA | 1 |
| Edwards, PC; Leslie, AG; Miller-Gallacher, JL; Nehmé, R; Schertler, GF; Tate, CG; Warne, T | 1 |
| Ahmari, SE; Barr, MM; Blanco, C; David, DJ; Gardier, AM; Hen, R; Le Dantec, Y; Nautiyal, KM; Tanaka, KF; Tritschler, L | 1 |
| Baker, J; Brown, GA; Congreve, M; Leslie, AG; Sato, T; Tate, CG; Warne, T | 1 |
| Dong, X; Wang, Y | 1 |
| Ahmari, SE; David, DJ; Gardier, AM; Hen, R; Nautiyal, KM; Tritschler, L | 1 |
| Bregman, T; Diwan, M; Fletcher, PJ; Hamani, C; Nobrega, JN; Raymond, R; Scott, B; Volle, J | 1 |
3 review(s) available for cyanopindolol and pindolol
| Article | Year |
|---|---|
Experimental QT interval prolongation.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Electrocardiography; Heart Conduction System; Long QT Syndrome; Nerve Growth Factors; Phenethylamines; Pindolol; Tetralones | 1992 |
Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity.
Topics: Amino Acid Sequence; Animals; Chimera; Cloning, Molecular; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pindolol; Protein Conformation; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1988 |
X-ray structure breakthroughs in the GPCR transmembrane region.
Topics: Animals; Cell Membrane; Humans; Models, Molecular; Molecular Conformation; Pindolol; Propanolamines; Protein Conformation; Receptor, Adenosine A2A; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Retinaldehyde; Rhodopsin; X-Ray Diffraction | 2009 |
1 trial(s) available for cyanopindolol and pindolol
| Article | Year |
|---|---|
Differences in beta-adrenergic receptor densities in omental and subcutaneous adipose tissue from obese African American and Caucasian women.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Black or African American; Cell Membrane; Female; Humans; Immunoblotting; Isoproterenol; Kinetics; Lipolysis; Obesity, Morbid; Omentum; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; White People | 2004 |
229 other study(ies) available for cyanopindolol and pindolol
| Article | Year |
|---|---|
Multiple heteroreceptors on limbic thalamic axons: M2 acetylcholine, serotonin1B, beta 2-adrenoceptors, mu-opioid, and neurotensin.
Topics: Atenolol; Autoradiography; Axons; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethanolamines; Limbic System; Neurotensin; Oxotremorine; Pindolol; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Neurotensin; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu; Receptors, Serotonin; Thalamus; Tritium | 1992 |
Localization of (-)-[125I]cyanopindolol binding in guinea-pig heart: characteristics of non-beta-adrenoceptor related binding in cardiac pacemaker and conducting regions.
Topics: Alprenolol; Animals; Ascorbic Acid; Binding Sites; Ethanolamines; Female; Guinea Pigs; Haloperidol; Heart Conduction System; Isoproterenol; Male; Myocardium; Peroxidase; Phentolamine; Pindolol; Propanolamines; Propranolol; Protein Binding; Receptors, Adrenergic, beta; Serotonin; Thiophenes; Trachea | 1992 |
Human retinal pigment epithelial cells possess beta 2-adrenergic receptors.
Topics: Adenylyl Cyclases; Betaxolol; Cells, Cultured; Cyclic AMP; Epinephrine; Humans; Isoproterenol; Norepinephrine; Pigment Epithelium of Eye; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1992 |
Functional properties of the rat and human beta 3-adrenergic receptors: differential agonist activation of recombinant receptors in Chinese hamster ovary cells.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Enzyme Activation; Humans; Isoproterenol; Pindolol; Rats; Receptors, Adrenergic, beta; Recombinant Proteins | 1992 |
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver.
Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Membrane; Imidazoles; Liver; Liver Glycogen; Male; Pindolol; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1992 |
Ligand binding to the porcine adipose tissue beta-adrenergic receptor.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Dihydroalprenolol; Guanosine Triphosphate; Kinetics; Ligands; Molecular Conformation; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Swine; Temperature; Time Factors | 1992 |
Regulation of cardiac adenylate cyclase activity in rodent models of obesity.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding, Competitive; Disease Models, Animal; GTP-Binding Proteins; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Membranes; Mice; Mice, Obese; Myocardium; Obesity; Pindolol; Rats; Rats, Zucker; Receptors, Adrenergic, beta; Stimulation, Chemical | 1992 |
[Airway epithelial beta 3-adrenergic receptor--effect on bioelectric properties and its mechanism of action].
Topics: Adrenergic beta-Agonists; Animals; Bumetanide; Calcium; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Epithelium; Ethanolamines; Membrane Potentials; Pindolol; Receptors, Adrenergic, beta; Trachea | 1992 |
Absence of mitochondrial beta-adrenoceptors in guinea pig myocardium: evidence for tissue disparity.
Topics: 5'-Nucleotidase; Adrenergic beta-Antagonists; Animals; Autoradiography; Azides; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Female; Guinea Pigs; Male; Mitochondria, Heart; Myocardium; Ouabain; Pindolol; Receptors, Adrenergic, beta; Sarcolemma; Sodium Azide; Sodium-Potassium-Exchanging ATPase | 1992 |
Coexisting beta 1- and atypical beta-adrenergic receptors cause redundant increases in cyclic AMP in human neuroblastoma cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cyclic AMP; Ethanolamines; Humans; Imidazoles; Isoproterenol; Neuroblastoma; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Effects of ischemia on regional ligand binding to adrenoceptors in the rat brain.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Brain; Dioxanes; Idazoxan; Ischemic Attack, Transient; Male; Pindolol; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic; Time Factors | 1992 |
Conversion of the human 5-HT1D beta serotonin receptor to the rat 5-HT1B ligand-binding phenotype by Thr355Asn site directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Line; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Pindolol; Rats; Receptors, Serotonin; Recombinant Proteins; Threonine | 1992 |
Role of 5-HT receptors in the effect of d-fenfluramine on feeding patterns in the rat.
Topics: Animals; Feeding Behavior; Fenfluramine; Male; Metergoline; Pindolol; Rats; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Stereoisomerism | 1992 |
Steady state levels of hepatic alpha 1- and beta 2-adrenergic receptors and gene transcripts during development of the male rat.
Topics: Age Factors; Animals; Blotting, Northern; Gene Expression; Liver; Male; Pindolol; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; RNA, Messenger | 1991 |
Increased lymphocyte beta-adrenergic receptor density in progressive multiple sclerosis is specific for the CD8+, CD28- suppressor cell.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; CD28 Antigens; CD8 Antigens; Cells, Cultured; Humans; Interleukin-2; Lymphocyte Activation; Middle Aged; Models, Biological; Multiple Sclerosis; Neurons, Afferent; Pindolol; Receptors, Adrenergic, beta; Recombinant Proteins; T-Lymphocyte Subsets; Up-Regulation | 1991 |
Reduced responsiveness of adenylate cyclase to forskolin in human lymphoma cells.
Topics: Adenylyl Cyclase Inhibitors; Aged; B-Lymphocytes; Binding Sites; Cholera Toxin; Colforsin; Cyclic AMP; Female; Humans; Isoproterenol; Lymphoma, Non-Hodgkin; Male; Middle Aged; Pindolol; Receptors, Adrenergic, beta; Signal Transduction; Tumor Cells, Cultured | 1991 |
Autoradiographic localization of beta-adrenergic receptors in human large coronary arteries.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Autoradiography; Binding, Competitive; Coronary Vessels; Female; Humans; Imidazoles; Male; Pindolol; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta; Silver; Tissue Distribution | 1991 |
Laminar alterations in gamma-aminobutyric acidA, muscarinic, and beta adrenoceptors and neuron degeneration in cingulate cortex in Alzheimer's disease.
Topics: Adrenergic beta-Antagonists; Aged; Alzheimer Disease; Gyrus Cinguli; Humans; Muscimol; Nerve Degeneration; Neurons; Pindolol; Pirenzepine; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Muscarinic | 1991 |
Beta receptor density in human lymphocyte membranes: changing with aging?
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Cell Membrane; Cyclic AMP; Dihydroalprenolol; Female; Humans; Lymphocytes; Male; Middle Aged; Norepinephrine; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta | 1991 |
Beta-adrenergic responsiveness of choroidal vasculature.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Animals; Autoradiography; Choroid; Female; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Pigment Epithelium of Eye; Pindolol; Rabbits; Receptors, Adrenergic, beta; Retinal Vessels; Timolol | 1991 |
Characterization of catecholamine-mediated relaxations in rat isolated gastric fundus: evidence for an atypical beta-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Catecholamines; Ethanolamines; Gastric Fundus; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Norepinephrine; Pindolol; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
Coexistence of three beta-adrenoceptor subtypes in white fat cells of various mammalian species.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Membrane; Cricetinae; Dogs; Ethanolamines; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Lipolysis; Male; Mesocricetus; Muscle, Smooth; Pindolol; Propanolamines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
Characterization of beta 1- and beta 2-adrenoceptors in rat skeletal muscles.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Binding, Competitive; Imidazoles; Male; Membranes; Muscles; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
Beta-2-adrenoceptors of polymorphonuclear leukocytes in children with atopic dermatitis. Their number and affinity to the radioligand [125I]-cyanopindolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Binding Sites; Child; Child, Preschool; Dermatitis, Atopic; Female; Humans; Infant; Male; Neutrophils; Pindolol; Receptors, Adrenergic, beta | 1991 |
Densitometric analysis of beta 1- and beta 2-adrenoceptors in guinea-pig atrioventricular conducting system.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Atrioventricular Node; Autoradiography; Densitometry; Female; Guinea Pigs; Heart Conduction System; Male; Pindolol; Propranolol; Proteins; Purkinje Cells; Receptors, Adrenergic, beta; Rosaniline Dyes; Staining and Labeling | 1990 |
Serotonergic mechanisms in the nucleus accumbens affected by chronic desipramine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Chromans; Desipramine; Dose-Response Relationship, Drug; Methysergide; Microinjections; Nucleus Accumbens; Pindolol; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Alterations in serotonin receptor subtypes in ethanol-dependent rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoholism; Animals; Brain; Ethanol; Ketanserin; Pindolol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Relations between contractile responses and beta-adrenoceptors in gastric fundus of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Pindolol; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stomach | 1991 |
Acute or chronic antidepressants do not modify [125I]cyanopindolol binding to 5-HT1B receptors in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Brain; Clomipramine; Female; Iodine Radioisotopes; Iprindole; Male; Pindolol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Thiazepines; Time Factors | 1991 |
Effects of in utero ethanol exposure on the developing serotonergic system.
Topics: Animals; Animals, Newborn; Brain Stem; Cerebral Cortex; Chromatography, High Pressure Liquid; Ethanol; Female; Iodine Radioisotopes; Male; Pindolol; Pregnancy; Prenatal Exposure Delayed Effects; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists | 1991 |
Hamster adipocyte alpha 2-adrenoceptor changes during fat mass modifications are not directly dependent on adipose tissue norepinephrine content.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cricetinae; Dioxanes; Energy Intake; Food Deprivation; Hydroxydopamines; Idazoxan; Lipolysis; Male; Mesocricetus; Norepinephrine; Oxidopamine; Pindolol; Quinoxalines; Receptors, Adrenergic, alpha; Sympathectomy, Chemical | 1990 |
Airway beta-adrenoceptor number in cystic fibrosis and asthma.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Bronchi; Bronchial Neoplasms; Bronchiectasis; Cell Membrane; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Lung; Male; Middle Aged; Muscle, Smooth; Pindolol; Receptors, Adrenergic, beta | 1990 |
Characterization of the beta-adrenergic transduction system in spleen mononuclear leukocyte membranes of young and senescent rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Cell Membrane; Cyclic AMP; Leukocytes, Mononuclear; Ligands; Male; Pindolol; Rats; Receptors, Adrenergic, beta; Signal Transduction; Spleen | 1990 |
Reserpine up-regulation of rat renal cortical beta adrenergic receptors is independent of its effect on the sympathetic nervous system.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Catecholamines; Guanethidine; Kidney Cortex; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Up-Regulation | 1990 |
Regulation of beta-adrenergic responsiveness during erythroid differentiation of Friend erythroleukemia cells.
Topics: Adrenergic beta-Antagonists; Animals; Cell Differentiation; Cell Membrane; Dimethyl Sulfoxide; Friend murine leukemia virus; GTP-Binding Proteins; Leukemia, Erythroblastic, Acute; Mice; Pindolol; Poly(ADP-ribose) Polymerases; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1990 |
Photoperiodic control of adipocyte alpha 2-adrenoceptors in Syrian hamsters: role of testosterone.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Cricetinae; Dioxanes; Idazoxan; Isoproterenol; Kidney; Light; Lipolysis; Male; Mesocricetus; Periodicity; Pindolol; Quinoxalines; Receptors, Adrenergic, alpha; Testosterone | 1990 |
Neuron-associated astroglial cells express beta- and alpha 1-adrenergic receptors in vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Cells, Cultured; Hippocampus; Pindolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1990 |
Beta-adrenergic receptors on human lymphocytes: comparison of down-regulation in vivo and in vitro.
Topics: Adrenergic beta-Antagonists; Down-Regulation; Humans; Isoproterenol; Lymphocytes; Pindolol; Receptors, Adrenergic, beta; Terbutaline; Time Factors | 1990 |
Quantitative autoradiography of beta-adrenergic receptors in rabbit eyes.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Ciliary Body; Cornea; Endothelium, Corneal; Epithelium; Eye; Female; Frozen Sections; Iris; Male; Pindolol; Rabbits; Receptors, Adrenergic, beta | 1990 |
Beta-adrenergic receptors in the rat mammary gland during pregnancy and lactation: characterization, distribution, and coupling to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Cytosol; Female; Gonadal Steroid Hormones; Kinetics; Lactation; Mammary Glands, Animal; Pindolol; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Progesterone; Tissue Distribution | 1990 |
Hormonal regulation of beta-adrenergic receptors in the rat mammary gland during the estrous cycle and lactation: role of sex steroids and prolactin.
Topics: Animals; Estrus; Female; Gonadal Steroid Hormones; Hormones; Lactation; Mammary Glands, Animal; Membranes; Ovariectomy; Pindolol; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1990 |
A mutation of the beta 2-adrenergic receptor impairs agonist activation of adenylyl cyclase without affecting high affinity agonist binding. Distinct molecular determinants of the receptor are involved in physical coupling to and functional activation of
Topics: Adenylyl Cyclases; Amino Acid Sequence; Cell Compartmentation; DNA Mutational Analysis; Endocytosis; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Isoproterenol; Macromolecular Substances; Molecular Sequence Data; Mutation; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1990 |
Sympathetic skin responses are decreased and lymphocyte beta-adrenergic receptors are increased in progressive multiple sclerosis.
Topics: Adult; Binding, Competitive; Cyclic AMP; Electric Stimulation; Female; Humans; Male; Membrane Potentials; Middle Aged; Multiple Sclerosis; Pindolol; Receptors, Adrenergic, beta; Skin; Sympathetic Nervous System; T-Lymphocytes | 1990 |
A 5-HT1-type receptor mediates the antinociceptive effect of nucleus raphe magnus stimulation in the rat.
Topics: Animals; Electric Stimulation; Evoked Potentials; Iontophoresis; Ketanserin; Nociceptors; Pindolol; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord | 1990 |
The effects of ageing on prejunctional 5-hydroxytryptamine receptors in the rat vas deferens.
Topics: Aging; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contraction; Pertussis Toxin; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Vas Deferens; Virulence Factors, Bordetella; Yohimbine | 1990 |
Characteristics and localisation of 125I ion binding in mammalian airways.
Topics: Animals; Ascorbic Acid; Dithiothreitol; Guinea Pigs; Humans; In Vitro Techniques; Iodides; Iodine Radioisotopes; Lung; Macaca fascicularis; Mice; Mice, Inbred CBA; Muscle, Smooth; Pindolol; Protein Binding; Rats; Rats, Inbred Strains; Sodium Iodide; Species Specificity; Swine; Trachea | 1990 |
Evidence that d-fenfluramine anorexia is mediated by 5-HT1 receptors.
Topics: Amidines; Animals; Appetite Depressants; Fenfluramine; Male; Metergoline; Pindolol; Piperidines; Rats; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1989 |
G protein dependent alterations in [125I]iodocyanopindolol and +/- cyanopindolol binding at 5-HT1B binding sites in rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Dihydroergotamine; Ethylmaleimide; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iodocyanopindolol; Magnesium Sulfate; Pindolol; Rats; Receptors, Serotonin | 1989 |
Apparent absence of serotonin1B receptors in biopsied and post-mortem human brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Biopsy; Brain; Female; Humans; Male; Pindolol; Postmortem Changes; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Tissue Preservation | 1989 |
Endotoxin-induced reduction of beta-adrenergic binding sites on splenic lymphocytes in vivo and in vitro: its modulation by anterior hypothalamic lesions.
Topics: Animals; Catecholamines; Cell Membrane; Endotoxins; Escherichia coli; Glucocorticoids; Guinea Pigs; Hypothalamic Hormones; Hypothalamus, Anterior; In Vitro Techniques; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Male; Pindolol; Receptors, Adrenergic, beta; Spleen; Thyroid Hormones | 1989 |
Up-regulation of guinea pig myometrial beta-adrenergic receptors by intrauterine estradiol and progesterone pellets.
Topics: Animals; Drug Implants; Estradiol; Female; Guinea Pigs; Myometrium; Osmolar Concentration; Pindolol; Progesterone; Receptors, Adrenergic, beta; Uterus | 1989 |
Rapid reduction in [3H]prazosin binding to gerbil forebrain membranes during bilateral common carotid artery occlusion.
Topics: Animals; Carotid Arteries; Cell Membrane; Cell Survival; Diencephalon; Gerbillinae; Ischemic Attack, Transient; Kinetics; Male; Neurons; Phospholipases A; Phospholipases A2; Pindolol; Prazosin; Quinuclidinyl Benzilate; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Telencephalon | 1989 |
Chronic norepinephrine elicits desensitization by uncoupling the beta-receptor.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dogs; Drug Tolerance; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Ventricles; Hemodynamics; Isoproterenol; Norepinephrine; Organ Size; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Ventricular Function | 1989 |
Guinea pig alveolar macrophages possess beta-adrenergic receptors.
Topics: Adrenergic beta-Antagonists; Animals; Guinea Pigs; Macrophages; Pindolol; Pulmonary Alveoli; Receptors, Adrenergic, beta; Timolol | 1989 |
Distribution of beta-adrenergic receptors in failing human myocardium. Implications for mechanisms of down-regulation.
Topics: Adrenergic beta-Antagonists; Adult; Autoradiography; Female; Heart Failure; Heart Transplantation; Humans; Iodine Radioisotopes; Male; Myocardium; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta | 1989 |
Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Brain; Guinea Pigs; Iodine Radioisotopes; Male; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Species Specificity | 1989 |
[Dependence of kinetic constants of intact human lymphocyte beta2-adrenoreceptors on the nature of the radioligands used].
Topics: Adrenergic beta-Antagonists; Alprenolol; Binding, Competitive; Ethylmaleimide; Humans; Isoproterenol; Kinetics; Lymphocytes; Pindolol; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta; Temperature | 1989 |
Influence of lactate on isoproterenol-induced lipolysis and beta-adrenoceptors distribution in human fat cells.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adult; Cell Membrane; Cells, Cultured; Humans; Isoproterenol; Lactates; Lipolysis; Middle Aged; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Serotonin Antagonists | 1989 |
Beta-adrenergic receptors in DMBA-induced rat mammary tumors: correlation with progesterone receptor and tumor growth.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Antagonists; Aging; Animals; Catecholamines; Female; Hormones; Iodine Radioisotopes; Kinetics; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Neoplasms, Hormone-Dependent; Ovariectomy; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Progesterone; Substrate Specificity | 1989 |
Identification and characterization of presynaptic and postsynaptic beta adrenoreceptors in the longitudinal smooth muscle/myenteric plexus of dog ileum.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Dogs; Ileum; In Vitro Techniques; Muscle, Smooth; Myenteric Plexus; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Subcellular Fractions | 1989 |
Treatment of oophorectomized guinea pigs with intrauterine 17 beta-estradiol pellets may modulate myometrial beta-adrenergic receptor binding properties.
Topics: Adrenergic beta-Antagonists; Animals; Estradiol; Female; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Myometrium; Ovariectomy; Pindolol; Progesterone; Receptors, Adrenergic, beta | 1989 |
Pregnancy-induced changes in the interaction of guinea pig myometrial beta-adrenergic receptors with l-isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Female; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Myometrium; Pindolol; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, beta | 1989 |
Chronic phenytoin treatment decreases GABAA but not beta-adrenoceptors in the cerebellum of young rats.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebellum; Female; Flunitrazepam; Kinetics; Muscimol; Phenytoin; Pindolol; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A; Tritium | 1989 |
Immune cytokine inhibition of beta-adrenergic agonist stimulated cyclic AMP generation in cardiac myocytes.
Topics: Animals; Animals, Newborn; Biological Products; Cells, Cultured; Culture Media; Cyclic AMP; Cytokines; Isoproterenol; Lymphocyte Activation; Lymphocytes; Macrophages; Myocardium; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Spleen | 1988 |
Decreased beta-adrenergic receptors in the leukocytes of depressed patients.
Topics: Adult; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Iodine Radioisotopes; Leukocytes; Middle Aged; Pindolol; Receptors, Adrenergic, beta; Schizophrenia | 1987 |
Regulation of guinea pig myometrial beta-adrenoreceptors by guanosine triphosphate and magnesium ion.
Topics: Animals; Female; Guanosine Triphosphate; Guinea Pigs; Iodine Radioisotopes; Isoproterenol; Magnesium; Myometrium; Pindolol; Pregnancy; Propranolol; Radioimmunoassay; Receptors, Adrenergic, beta | 1988 |
Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone.
Topics: Animals; Binding, Competitive; Cell Membrane; Gene Expression Regulation; Male; Nucleic Acid Hybridization; Orchiectomy; Pindolol; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; RNA, Messenger; Testosterone; Transcription, Genetic | 1988 |
Use of electrofocusing for the analysis and purification of turkey erythrocytes beta 1-adrenoceptors.
Topics: Acrylic Resins; Animals; Binding, Competitive; Chromatography, Affinity; Digitonin; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Hydrogen-Ion Concentration; Iodine Radioisotopes; Isoelectric Focusing; Pindolol; Receptors, Adrenergic, beta; Turkeys | 1988 |
Demonstration of beta-adrenergic receptors in rat nasal glands by an in vitro autoradiographic technique.
Topics: Adrenergic Fibers; Animals; Autoradiography; In Vitro Techniques; Nasal Mucosa; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1988 |
Autoradiographic localization of beta-adrenoreceptors in rat uterus.
Topics: Animals; Autoradiography; Binding, Competitive; Epithelium; Ethanolamines; Female; Iodine Radioisotopes; Myometrium; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tissue Distribution; Uterus | 1988 |
Adrenoceptor and imipramine receptor binding during the menstrual cycle.
Topics: Adult; Blood Platelets; Carrier Proteins; Dihydroergotoxine; Female; Humans; Imipramine; Lymphocytes; Menstrual Cycle; Pindolol; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Neurotransmitter | 1988 |
GR43175, a selective agonist for the 5-HT1-like receptor in dog isolated saphenous vein.
Topics: Animals; Cats; Dogs; Female; In Vitro Techniques; Indoles; Male; Methiothepin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pindolol; Rabbits; Rats; Receptors, Serotonin; Saphenous Vein; Serotonin Antagonists; Sulfonamides; Sumatriptan; Swine; Tropanes; Vagus Nerve | 1988 |
Beta-adrenoceptors in circular and longitudinal myometrial membranes and in lung membranes from dioestrous and post-partum guinea-pigs.
Topics: Animals; Autoradiography; Diestrus; Extraembryonic Membranes; Female; Guinea Pigs; Lung; Myometrium; Pindolol; Pregnancy; Receptors, Adrenergic, beta | 1988 |
Cyanopindolol is a highly potent and selective antagonist at the presynaptic serotonin autoreceptor in the rat brain cortex.
Topics: Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Isoproterenol; Male; Pindolol; Propanolamines; Rats; Receptors, Serotonin; Stereoisomerism | 1985 |
Analysis of agonist dissociation constants as assessed by functional antagonism in guinea pig left atria.
Topics: Adenosine; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzofurans; Carbachol; Catechols; Gallopamil; Guinea Pigs; Heart; In Vitro Techniques; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Myocardial Contraction; Nifedipine; Pindolol; Propanolamines | 1986 |
Evidence for tyrosine at the ligand binding center of beta-adrenergic receptors.
Topics: Adrenergic beta-Antagonists; Animals; Anura; Binding Sites; Cattle; Cell Membrane; Guinea Pigs; Ligands; Pindolol; Rabbits; Rats; Receptors, Adrenergic, beta; Species Specificity; Turkeys; Tyrosine | 1986 |
Characteristics of the beta-adrenergic receptor in the rat ventral prostate using [125I]cyanopindolol.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Chemical Precipitation; Epinephrine; Isoproterenol; Male; Norepinephrine; Pindolol; Polyethylene Glycols; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus.
Topics: 5-Methoxytryptamine; 5,7-Dihydroxytryptamine; Adrenergic beta-Antagonists; Animals; Atenolol; Binding, Competitive; Ethanolamines; Hippocampus; In Vitro Techniques; Male; Membranes; Pindolol; Propranolol; Rats; Receptors, Serotonin; Serotonin | 1987 |
A bromoacetylated analogue of cyanopindolol: an irreversible antagonist at rat beta-adrenoceptors.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Brain; Dihydroalprenolol; Erythrocytes; Lung; Metabolic Clearance Rate; Myocardium; Pindolol; Rats; Receptors, Adrenergic, beta; Time Factors | 1987 |
The distribution of beta-adrenoceptors in dog kidney: an autoradiographic analysis.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Dogs; Female; In Vitro Techniques; Iodine Radioisotopes; Kidney; Male; Pindolol; Receptors, Adrenergic, beta | 1987 |
Alterations of beta-adrenergic, muscarinic cholinergic receptors and imipramine binding sites in human lung tumors.
Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Carcinoma, Squamous Cell; Humans; Imipramine; In Vitro Techniques; Lung Neoplasms; Pindolol; Quinuclidinyl Benzilate; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Muscarinic | 1987 |
Gi affects the agonist-binding properties of beta-adrenoceptors in the presence of Gs.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Catalysis; Cholera Toxin; Erythrocyte Membrane; GTP-Binding Proteins; Isoproterenol; Lymphoma; Pertussis Toxin; Pindolol; Receptors, Adrenergic, beta; Turkeys; Virulence Factors, Bordetella | 1988 |
Characterization and localization of (-)[125I]-cyanopindolol binding to non-beta-adrenoceptor sites in dog kidney.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Binding, Competitive; Dogs; Female; In Vitro Techniques; Iodine Radioisotopes; Kidney; Kinetics; Male; Membranes; Pindolol; Radioligand Assay | 1987 |
Determination of beta adrenoceptor density on rabbit mononuclear leukocytes.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Cell Membrane; Cell Separation; Cimetidine; Leukocytes, Mononuclear; Male; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic, beta | 1988 |
Beta-adrenergic receptors of lymphocytes in children with allergic respiratory diseases.
Topics: Adrenergic beta-Antagonists; Asthma; Bronchial Provocation Tests; Child; Female; Humans; Immunoglobulin E; Iodine Radioisotopes; Lymphocytes; Male; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Rhinitis, Allergic, Seasonal | 1988 |
Regulation of beta-adrenoceptors by catecholamines in the rabbit skeletal muscle.
Topics: Adrenergic beta-Antagonists; Animals; Epinephrine; Male; Metoprolol; Muscles; Norepinephrine; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta | 1988 |
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1988 |
Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites.
Topics: Animals; Cerebral Cortex; In Vitro Techniques; Isoproterenol; Ketanserin; Kinetics; Male; Pindolol; Piperidines; Rats; Receptors, Serotonin; Serotonin Antagonists; Subcellular Fractions; Swine | 1986 |
The serotonin (5-HT) autoreceptor in the hippocampus of the rabbit: role of 5-HT biophase concentration.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Mathematics; Metergoline; Methiothepin; Methoxydimethyltryptamines; Methysergide; Phentolamine; Pindolol; Quipazine; Rabbits; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1987 |
Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ketanserin; Male; Metergoline; Methiothepin; Muscle, Smooth, Vascular; Pindolol; Receptors, Serotonin; Tetrahydronaphthalenes; Vasodilation | 1988 |
Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Indoles; Ketanserin; Male; Neurons, Afferent; Pain; Physical Stimulation; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes | 1988 |
Identification of the subunit structure of rat pineal adrenergic receptors by photoaffinity labeling.
Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Cell Membrane; Liver; Molecular Weight; Phenethylamines; Photochemistry; Pindolol; Pineal Gland; Propanolamines; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Spleen; Tetralones | 1986 |
Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate.
Topics: Adenylyl Cyclases; Animals; Butyrates; Butyric Acid; Cell Membrane; Cells, Cultured; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Pindolol; Rats; Receptors, Adrenergic, beta | 1986 |
Autoradiographic analysis of the distribution of beta-adrenoceptors in the dog splenic vasculature.
Topics: Animals; Autoradiography; Dogs; In Vitro Techniques; Iodine Radioisotopes; Muscle, Smooth, Vascular; Pindolol; Receptors, Adrenergic, beta; Spleen; Splenic Artery | 1986 |
Characterization of beta-1 and beta-2 adrenoceptors in guinea pig atrium: functional and receptor binding studies.
Topics: Animals; Electric Stimulation; Ethanolamines; Female; Guinea Pigs; Heart Atria; Heart Rate; Imidazoles; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Pindolol; Procaterol; Propanolamines; Receptors, Adrenergic, beta; Stimulation, Chemical; Uterine Contraction; Uterus | 1987 |
Autoradiographic localization of beta-1 and beta-2 adrenoceptors in guinea pig atrium and regions of the conducting system.
Topics: Animals; Autoradiography; Binding, Competitive; Guinea Pigs; Heart Atria; Heart Conduction System; Imidazoles; Isomerism; Kinetics; Myocardium; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1987 |
Beta-adrenoceptors in human tracheal smooth muscle: characteristics of binding and relaxation.
Topics: Atenolol; Binding, Competitive; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pindolol; Propranolol; Receptors, Adrenergic, beta; Sarcolemma; Stereoisomerism; Trachea | 1987 |
Beta-adrenergic receptor subtype is an intrinsic property of the receptor gene product.
Topics: Animals; Cricetinae; Gene Expression Regulation; Mice; Pindolol; Protein Processing, Post-Translational; Receptors, Adrenergic, beta; Transfection | 1987 |
(-)-Propranolol and (+/-)-cyanopindolol are mixed agonists-antagonists at serotonin autoreceptors in the hippocampus of the rat brain.
Topics: Animals; Hippocampus; Male; Pindolol; Potassium; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereoisomerism; Synaptosomes | 1987 |
Effects of RU 24969 on serotonin release in rat brain cortex: further support for the identity of serotonin autoreceptors with 5-HT1B sites.
Topics: Animals; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Indoles; Male; Monoamine Oxidase; Pindolol; Potassium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptosomes | 1987 |
Additive effects of growth hormone and testosterone on lipolysis in adipocytes of hypophysectomized rats.
Topics: Adipocytes; Adrenergic beta-Antagonists; Animals; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Growth Hormone; Hypophysectomy; Lipolysis; Male; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Testosterone; Weight Gain | 1995 |
Forskolin-stimulated adenylyl cyclase activity is decreased but beta 2-adrenoceptor function is unchanged in primary hypertension.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Binding, Competitive; Cell Membrane; Colforsin; Female; Hemodynamics; Humans; Hypertension; Isoproterenol; Leukocytes, Mononuclear; Male; Middle Aged; Pindolol; Receptors, Adrenergic, beta; Sex Factors | 1993 |
Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Genotype; Humans; Isoproterenol; Muscle, Smooth; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta-2; Second Messenger Systems; Signal Transduction; Trachea | 1995 |
Effects of thyroid hormone on norepinephrine signaling in brown adipose tissue. I. Beta 1- and beta 2-adrenergic receptors and cyclic adenosine 3',5'-monophosphate generation.
Topics: Adipose Tissue, Brown; Adrenergic Agents; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Hypothyroidism; Norepinephrine; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Reference Values; Signal Transduction; Temperature; Thyroid Hormones | 1995 |
5-HT receptors mediating contractions of the isolated human coronary artery.
Topics: Adolescent; Adult; Arteries; Blood Platelets; Child; Child, Preschool; Coronary Vessels; Dose-Response Relationship, Drug; Ergotamine; Female; Humans; In Vitro Techniques; Infant; Ketanserin; Male; Metergoline; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Pindolol; Potassium; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Substance P; Sumatriptan; Yohimbine | 1993 |
Reduced adenylyl cyclase activation with no decrease in beta-adrenergic receptors in basenji greyhound leukocytes: relevance to beta-adrenergic responses in airway smooth muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Dogs; Enzyme Activation; Flow Cytometry; GTP-Binding Proteins; Immunoblotting; Leukocytes; Lymphocyte Subsets; Muscle, Smooth; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Trachea | 1995 |
The 5-HT1B receptor mediates the effect of d-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Drug Interactions; Eating; Ergolines; Fenfluramine; Hyperphagia; Hypothalamus; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Male; Metergoline; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Identification of beta-adrenoceptors in rat lymph nodes and spleen: an autoradiographic study.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Image Processing, Computer-Assisted; Ligands; Lymph Nodes; Male; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Serotonin; Spleen | 1994 |
Is the "atypical" beta-receptor in the rat stomach fundus the rat beta 3 receptor?
Topics: Adenylyl Cyclases; Animals; CHO Cells; Cricetinae; Dioxoles; Enzyme Activation; Gene Expression; In Vitro Techniques; Male; Muscle Relaxation; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Stomach | 1995 |
Atypical beta-adrenoceptor in bovine adrenal medulla.
Topics: Adrenal Medulla; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cattle; Cell Degranulation; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta | 1994 |
Adrenergic receptors in the cerebellum of olivopontocerebellar atrophy.
Topics: Aged; Brimonidine Tartrate; Cerebellar Cortex; Cerebellum; Humans; Nerve Tissue Proteins; Norepinephrine; Olivopontocerebellar Atrophies; Pindolol; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta | 1994 |
Adrenaline stimulated cyclic adenosine monophosphate response in leucocytes is reduced after prolonged physical activity combined with sleep and energy deprivation.
Topics: Adrenergic beta-Antagonists; Adult; Binding Sites; Binding, Competitive; Cells, Cultured; Cyclic AMP; Epinephrine; Fasting; Granulocytes; Humans; Leukocytes; Male; Monocytes; Physical Exertion; Pindolol; Sleep Deprivation; Time Factors; Timolol | 1994 |
Increased proliferative activity, loss of beta-adrenergic receptor function and class I major histocompatibility complex antigen surface expression in a modified lymphoma cell line.
Topics: Adrenergic beta-Antagonists; Animals; Biomarkers; Cell Division; Histocompatibility Antigens Class I; Lymphoma; Mice; Pindolol; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1994 |
Coexisting beta-1 and beta-2-adrenergic receptors with differential receptor reserves in rat C6 glioma cells.
Topics: Animals; Cyclohexane Monoterpenes; Dexamethasone; Glioma; Guanosine Triphosphate; In Vitro Techniques; Pindolol; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Tumor Cells, Cultured | 1995 |
Response of mouse proximal straight tubule and medullary thick ascending limb to beta-agonist.
Topics: Adrenergic beta-Antagonists; Animals; Electrophysiology; Furosemide; In Vitro Techniques; Isoproterenol; Kidney Medulla; Kidney Tubules; Kidney Tubules, Proximal; Kinetics; Membrane Potentials; Mice; Perfusion; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta | 1993 |
[Increase in beta-adrenergic receptors in rabbits in long-term local administration of beta-blockers].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Autoradiography; Ciliary Body; Cornea; Long-Term Care; Male; Pindolol; Rabbits; Receptors, Adrenergic, beta-2; Timolol | 1993 |
Autoradiographic localization and quantitation of beta 1- and beta 2-adrenoceptors in the human atrioventricular conducting system: a comparison of patients with idiopathic dilated cardiomyopathy and ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrioventricular Node; Binding, Competitive; Bundle of His; Cardiomyopathy, Dilated; Down-Regulation; Female; Heart Septum; Humans; Imidazoles; Male; Middle Aged; Muscle Proteins; Myocardial Ischemia; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1994 |
The role of 5-hydroxytryptamine1A (5-HT1A) receptors in the anticonflict activity of beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Betaxolol; Conflict, Psychological; Disease Models, Animal; Drug Interactions; Male; p-Chloroamphetamine; Pindolol; Piperazines; Prazosin; Propanolamines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 1994 |
Regulation of beta-adrenoceptors in the guinea-pig sinoatrial node.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Catechols; Chromatography, High Pressure Liquid; Densitometry; Down-Regulation; Drug Interactions; Female; Guinea Pigs; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Sinoatrial Node | 1994 |
Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Ergolines; Male; Motor Activity; Pindolol; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Ventral Tegmental Area | 1994 |
Enhanced aggressive behavior in mice lacking 5-HT1B receptor.
Topics: Aggression; Animals; Brain Chemistry; Chimera; Female; Indoles; Male; Mice; Motor Activity; Mutation; Pindolol; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombination, Genetic; Serotonin Receptor Agonists | 1994 |
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; Cyclic AMP; Dogs; Ethanolamines; Female; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1993 |
Beta-adrenergic receptors in the hippocampal and retrohippocampal regions of rats and guinea pigs: autoradiographic and immunohistochemical studies.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Guinea Pigs; Hippocampus; Immunohistochemistry; Limbic System; Male; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tissue Distribution; Tyrosine 3-Monooxygenase | 1993 |
Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium.
Topics: Adrenergic beta-Antagonists; Binding, Competitive; Cocaine; Dihydroergotoxine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoproterenol; Least-Squares Analysis; Molecular Structure; Myometrium; Pindolol; Pregnancy; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1993 |
Studies on the intrinsic activity (efficacy) of human adrenergic receptors. Co-expression of beta 1 and beta 2 reveals a lower efficacy for the beta 1 receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Humans; L Cells; Mice; Molecular Sequence Data; Myocardium; Pindolol; Receptors, Adrenergic, beta | 1994 |
Guanine nucleotide regulatory protein alterations in young Milan hypertensive strain rats.
Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Colforsin; GTP-Binding Proteins; Hypertension; Immune Sera; Isoproterenol; Molecular Sequence Data; Muscle, Smooth, Vascular; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Effects of the 5-HT receptor antagonists cyanopindolol, ICI 169,369, cisapride and granisetron on neuroleptic-induced catalepsy in mice.
Topics: Animals; Buspirone; Catalepsy; Cisapride; Female; Granisetron; Haloperidol; Male; Mice; Pindolol; Piperidines; Quinolines; Serotonin Antagonists; Time Factors | 1993 |
5-HT1B receptors mediate potent contractile responses to 5-HT in rat caudal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Ergolines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pindolol; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Vasoconstrictor Agents | 1993 |
Verapamil induced reduction of the myocardial beta-adrenoceptor density in BIO 14.6 cardiomyopathic Syrian hamsters.
Topics: Animals; Binding, Competitive; Calcium Channels; Cardiomyopathies; Cricetinae; Disease Models, Animal; Heart; Mesocricetus; Myocardium; Pindolol; Receptors, Adrenergic, beta; Verapamil | 1993 |
The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amidines; Animals; Anorexia; Anorexia Nervosa; Disease Models, Animal; Feeding Behavior; Ketanserin; Male; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Ritanserin; Stress, Physiological | 1993 |
The role of hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptors in the anticonflict activity of beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Hippocampus; Male; Pindolol; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1995 |
Effects of chronic infusion of (-)-isoprenaline on rat cardiac muscarinic (M2)-cholinoceptors and beta 1- and beta 2-adrenoceptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Binding, Competitive; Down-Regulation; Heart Ventricles; Imidazoles; Infusion Pumps, Implantable; Isoproterenol; Male; Myocardium; N-Methylscopolamine; Pindolol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Muscarinic; Scopolamine Derivatives | 1995 |
Characterization and localization of atypical beta-adrenoceptors in rat ileum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Binding, Competitive; Female; Ileum; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 1995 |
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Depression, Chemical; Dioxanes; Dopamine Antagonists; Drug Interactions; Female; Ketanserin; Male; Motor Neurons; Oxadiazoles; Pindolol; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Sumatriptan | 1995 |
Different atypical beta-adrenoceptors mediate isoprenaline-induced relaxation in vascular and non-vascular smooth muscles.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ethanolamines; Female; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Pindolol; Rats; Receptors, Adrenergic, beta | 1995 |
Atypical responses of rat ileum to pindolol, cyanopindolol and iodocyanopindolol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; Ileum; In Vitro Techniques; Iodocyanopindolol; Male; Muscle Relaxation; Pindolol; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1996 |
Abnormalities in 5-HT1A and 5-HT1B receptor binding in severe-seizure genetically epilepsy-prone rats (GEPR-9s).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Epilepsy; Male; Pindolol; Rats; Receptors, Serotonin; Serotonin Antagonists | 1996 |
Inducible expression of beta 1- and beta 2-adrenergic receptors in rat C6 glioma cells: functional interactions between closely related subtypes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Cyclic AMP; Epinephrine; Gene Expression Regulation, Neoplastic; Genomic Library; Glioma; Imidazoles; Isopropyl Thiogalactoside; Isoproterenol; Kinetics; Norepinephrine; Pindolol; Radioligand Assay; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1996 |
Characterization of binding sites for beta-adrenergic agonists and vasoactive intestinal peptide in the rat harderian gland.
Topics: Animals; Binding Sites; Binding, Competitive; Harderian Gland; Male; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide | 1996 |
Comparison of the densities of 5-HT4 receptors, beta 1- and beta 2-adrenoceptors in human atrium: functional implications.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Binding, Competitive; Catecholamines; Dioxanes; Heart Atria; Humans; Iodine Radioisotopes; Isotope Labeling; Male; Middle Aged; Myocardial Contraction; Pindolol; Piperidines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Regression Analysis; Serotonin Antagonists | 1996 |
Identification and functional role of beta-adrenergic receptor subtypes in primate and rodent: in vivo versus isolated myocytes.
Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Pressure; Cells, Cultured; Coronary Vessels; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Papio; Pindolol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Vascular Resistance; Ventricular Function, Left; Ventricular Function, Right | 1996 |
A new peptide, 5-HT-moduline, isolated and purified from mammalian brain specifically interacts with 5-HT1B/1D receptors.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain Chemistry; Cell Line; Cerebral Cortex; Chromatography, High Pressure Liquid; In Vitro Techniques; Membranes; Mice; Molecular Sequence Data; Neuropeptides; Oligopeptides; Pindolol; Rats; Receptors, Serotonin | 1996 |
Role of 5-HT1b receptor in the pressure-induced behavioral and neurochemical disorders in rats.
Topics: Adrenergic beta-Agonists; Animals; Atmospheric Pressure; Behavior, Animal; Brain Chemistry; Calibration; Dopamine; Electrochemistry; Electrodes; High Pressure Neurological Syndrome; Isoproterenol; Male; Motor Activity; Neostriatum; Pindolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Propranolol therapy in experimental heart failure in rabbits improves cardiac response to catecholamines without beta-adrenoceptor up-regulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Catecholamines; Female; Heart; Heart Function Tests; Heart Rate; Hemodynamics; Isoproterenol; Male; Myocardium; Norepinephrine; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic, beta; Up-Regulation; Ventricular Function | 1995 |
Mutations of Tyr326 in the beta 2-adrenoceptor disrupt multiple receptor functions.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alanine; Animals; Cell Membrane; CHO Cells; Cloning, Molecular; Cricetinae; Gene Expression; Humans; Iodine Radioisotopes; Isoproterenol; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Pindolol; Protein Binding; Radioligand Assay; Receptors, Adrenergic, beta-2; Transfection; Tyrosine | 1996 |
Effect of endurance physical training on rat liver adenylyl cyclase system.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Colforsin; Enzyme Activation; Fluorides; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Manganese; Physical Conditioning, Animal; Physical Endurance; Pindolol; Random Allocation; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1996 |
Developmental expression and functional activity of beta 1- and beta 3-adrenoceptors in murine 3T3-F442A differentiating adipocytes.
Topics: Adenylyl Cyclases; Adipocytes; Animals; Base Sequence; Cell Differentiation; Cell Line; Lipolysis; Membranes; Molecular Sequence Data; Pindolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-3; RNA, Messenger; Signal Transduction | 1996 |
Mediation of the positive chronotropic effect of CGP 12177 and cyanopindolol in the pithed rat by atypical beta-adrenoceptors, different from beta 3-adrenoceptors.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Male; Pindolol; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stimulation, Chemical | 1996 |
Differences between the third cardiac beta-adrenoceptor and the colonic beta 3-adrenoceptor in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Colon; Dose-Response Relationship, Drug; Female; Heart; Male; Norepinephrine; Pindolol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1996 |
Characterization of a 5-HT1B receptor on CHO cells: functional responses in the absence of radioligand binding.
Topics: Animals; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Pindolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1996 |
Growth hormone treatment of hypophysectomized rats increases catecholamine-induced lipolysis and the number of beta-adrenergic receptors in adipocytes: no differences in the effects of growth hormone on different fat depots.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Female; Growth Hormone; Hypophysectomy; Iodine Radioisotopes; Isoproterenol; Lipolysis; Male; Norepinephrine; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1996 |
Characteristics of cyanopindolol analogues active at the beta 3-adrenoceptor in rat ileum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Ethanolamines; Female; Ileum; Iodocyanopindolol; Linear Models; Male; Muscle Relaxation; Pindolol; Rats | 1996 |
Characterization of adrenoceptor types and subtypes in American bullfrogs acclimated to warm or cold temperature.
Topics: Acclimatization; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Humans; Idazoxan; Kidney; Membrane Proteins; Myocardium; Pindolol; Prazosin; Radioligand Assay; Rana catesbeiana; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Spinal Cord; Temperature | 1996 |
Modulation of cortical acetylcholine release by serotonin: the role of substance P interneurons.
Topics: Acetylcholine; Animals; Capsaicin; Hippocampus; Humans; Indoles; Isoindoles; Neurokinin-1 Receptor Antagonists; Pindolol; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Substance P; Tetrodotoxin | 1996 |
Beta 3-adrenoceptors mediating relaxation of the oesophageal tunica muscularis mucosae and distal colon in the rat: comparative pharmacology and their desensitization by BRL 37344.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Dose-Response Relationship, Drug; Esophagus; Ethanolamines; Isoproterenol; Male; Muscle Relaxation; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1996 |
Stereoselective modification of circular dichroism spectra of rat lung beta-adrenoceptor protein preparation by enantiomers of epinephrine.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cattle; Circular Dichroism; Epinephrine; In Vitro Techniques; Lung; Membranes; Pindolol; Rats; Receptors, Adrenergic, beta; Serum Albumin, Bovine; Stereoisomerism | 1996 |
Expression of beta 2-adrenoceptors in halobacteria.
Topics: Adrenergic Antagonists; Animals; Bacteriorhodopsins; Blotting, Northern; Blotting, Western; Genetic Vectors; Halobacterium; Humans; Pindolol; Polymerase Chain Reaction; Receptors, Adrenergic, beta-2; Recombinant Proteins | 1997 |
Characterization of a beta 3-adrenoceptor stimulating gastrin and somatostatin secretions in rat antrum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; DNA, Complementary; Female; Gastrins; Pindolol; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Somatostatin; Tetrahydronaphthalenes | 1997 |
Distribution of beta-adrenoceptor subtypes in gastrointestinal tract of nondiabetic and diabetic BB rats. A longitudinal study.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Digestive System; Male; Pindolol; Rats; Rats, Inbred BB; Receptors, Adrenergic, beta; Time Factors | 1997 |
The developmental and physiological consequences of disrupting genes encoding beta 1 and beta 2 adrenoceptors.
Topics: Adrenergic beta-Antagonists; Animals; Crosses, Genetic; Homozygote; Imidazoles; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Pindolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Stem Cells | 1998 |
A dual effect of 5-HT1B receptor stimulation on nociceptive dorsal horn neurones in rats.
Topics: Action Potentials; Animals; Drug Interactions; Electric Stimulation; Female; Neurons; Pain; Pindolol; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission | 1997 |
Early expression of a beta1-adrenergic receptor and catecholamines in Xenopus oocytes and embryos.
Topics: Animals; Base Sequence; Catecholamines; DNA, Complementary; Gene Expression; Gene Expression Regulation, Developmental; Molecular Sequence Data; Oocytes; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta-1; Sequence Alignment; Sequence Homology, Amino Acid; Xenopus laevis | 1997 |
Further evidence for differences between cardiac atypical beta-adrenoceptors and brown adipose tissue beta3-adrenoceptors in the pithed rat.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Male; Pindolol; Propanolamines; Rats; Rats, Wistar; Temperature | 1997 |
Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists.
Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; CHO Cells; Chromatography, Thin Layer; Cricetinae; Glioma; Humans; Isoxazoles; Magnetic Resonance Spectroscopy; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Tumor Cells, Cultured | 1998 |
Molecular mechanisms of adenylyl cyclase desensitization in pregnant rat myometrium following in vivo administration of the beta-adrenergic agonist, isoproterenol.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Drug Tolerance; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Myometrium; Pindolol; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Pharmacological and molecular characterisation of beta-adrenoceptors in adult rat diaphragm muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Dose-Response Relationship, Drug; Fenoterol; Imidazoles; Isoproterenol; Male; Muscle, Smooth; Pindolol; Prenalterol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 1998 |
Atypical adrenoceptor-mediated relaxation of canine pulmonary artery through a cAMP-dependent pathway.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cyclic AMP; Dioxoles; Dogs; Ethanolamines; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Pindolol; Propanolamines; Pulmonary Artery; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1998 |
Native 5-HT1B receptors expressed in OK cells display dual coupling to elevation of intracellular calcium concentrations and inhibition of adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Kidney; Methiothepin; Opossums; Oxadiazoles; Pertussis Toxin; Pindolol; Piperazines; Pyridines; Pyrroles; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Virulence Factors, Bordetella | 1998 |
Pharmacological profile of the prejunctional 5-HT1 receptors mediating inhibition of sympathetic vasopressor outflow in the pithed rat.
Topics: 5-Methoxytryptamine; Animals; Blood Pressure; Central Nervous System; Oxadiazoles; Pindolol; Piperazines; Pyridines; Pyrroles; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathetic Nervous System | 1998 |
Alterations in cardiac membrane beta-adrenoceptors and adenylyl cyclase due to hypochlorous acid.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hypochlorous Acid; Immunoblotting; Isoproterenol; Lipid Peroxidation; Methionine; Myocardium; Pertussis Toxin; Pindolol; Propane; Rats; Receptors, Adrenergic; Sodium Fluoride; Virulence Factors, Bordetella | 1999 |
Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation.
Topics: Animals; Binding, Competitive; Evolution, Molecular; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Histidine; Humans; Isoproterenol; Models, Molecular; Mutation; Pindolol; Protein Engineering; Protein Structure, Secondary; Receptors, Adrenergic, beta-2; Receptors, Parathyroid Hormone; Rod Opsins; Secretin; Sequence Alignment; Signal Transduction; Zinc | 1999 |
Serotonergic modulation of hyperpolarization-activated current in acutely isolated rat dorsal root ganglion neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Cell Size; Cyclic Nucleotide-Gated Cation Channels; Dopamine Antagonists; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Pindolol; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1999 |
Effect of a 14-day hindlimb suspension on beta-adrenoreceptors in rats.
Topics: Adrenergic beta-Antagonists; Animals; Heart Atria; Heart Ventricles; Hindlimb Suspension; Kidney; Male; Pindolol; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1999 |
Coupling efficiencies of beta 1- and beta 2-adrenergic receptors expressed alone or together in transfected GH3 pituitary cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cells, Cultured; Cyclic AMP; Imidazoles; Iodine Radioisotopes; Isopropyl Thiogalactoside; Isoproterenol; Kinetics; Pindolol; Pituitary Gland, Anterior; Propanolamines; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Transfection | 1999 |
5-HT1B antagonists modulate clearance of extracellular serotonin in rat hippocampus.
Topics: Analysis of Variance; Animals; Corpus Callosum; Hippocampus; Male; Metabolic Clearance Rate; Methiothepin; Neuropeptides; Oligopeptides; Pindolol; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists | 1999 |
Characterisation of the atypical beta-adrenoceptor in rabbit isolated jejunum using BRL 37344, cyanopindolol and SR 59230A.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Ethanolamines; Female; In Vitro Techniques; Isoproterenol; Jejunum; Male; Pindolol; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta | 1999 |
Beta1- and beta3-adrenoceptors mediate relaxation in ovine trachealis smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Ethanolamines; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-3; Sheep; Trachea | 1999 |
Mechanisms of impaired beta-adrenergic receptor signaling in G(alphaq)-mediated cardiac hypertrophy and ventricular dysfunction.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cardiomegaly; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Humans; Iodine Radioisotopes; Mice; Mice, Transgenic; Patch-Clamp Techniques; Pindolol; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Dysfunction | 2000 |
Engineering of a proteolytically stable human beta 2-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells.
Topics: Adrenergic beta-Antagonists; Animals; ATP-Binding Cassette Transporters; Baculoviridae; Carrier Proteins; Chromatography, Affinity; Diazomethane; Escherichia coli; Escherichia coli Proteins; Genetic Engineering; GTP-Binding Proteins; Humans; Maltose-Binding Proteins; Monosaccharide Transport Proteins; Periplasmic Binding Proteins; Photoaffinity Labels; Pindolol; Receptors, Adrenergic, beta; Recombinant Fusion Proteins; Spodoptera; Transfection | 2000 |
Beta 1-, beta 2- and atypical beta-adrenoceptor-mediated relaxation in rat isolated aorta.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Bupranolol; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Pindolol; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Substrate Specificity; Vasodilator Agents | 2000 |
Role of endothelium/nitric oxide in atypical beta-adrenoceptor-mediated relaxation in rat isolated aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Oxadiazoles; Phenoxyacetates; Phenoxypropanolamines; Phenylacetates; Pindolol; Propanolamines; Propranolol; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vasodilation | 2000 |
Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s).
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Binding Sites; Brimonidine Tartrate; CHO Cells; Cricetinae; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Kinetics; Oxymetazoline; Pindolol; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin Antagonists; Signal Transduction; Swine; Yohimbine | 2000 |
Beta-adrenoceptors in equine trachea and heart.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Female; Heart Atria; Heart Ventricles; Horses; Imidazoles; Iodine Radioisotopes; Ligands; Male; Muscle, Smooth; Myocardium; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Regression Analysis; Spectrometry, Gamma; Trachea | 1999 |
Mechanism of anemia associated with autonomic dysfunction in rats.
Topics: Adrenergic beta-Antagonists; Anemia; Animals; Autonomic Nervous System Diseases; Blood Cell Count; Blood Pressure; Epinephrine; Erythrocytes; Erythropoietin; Female; Hematocrit; Hemoglobins; Norepinephrine; Oxidopamine; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sympatholytics | 2000 |
5-HT(1B) receptor-mediated regulation of serotonin clearance in rat hippocampus in vivo.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Drug Synergism; Electrochemistry; Extracellular Space; Fenclonine; Fluvoxamine; Hippocampus; Male; Metabolic Clearance Rate; Microinjections; Pindolol; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 2000 |
Opioid tolerance/dependence in neuroblastoma x glioma (NG108-15) hybrid cells is associated with a reduction in spontaneous stimulatory receptor activity.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; COS Cells; Drug Tolerance; Enzyme Inhibitors; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Iodine Radioisotopes; Morphine; Narcotics; Neuroblastoma; Pindolol; Propanolamines; Receptors, Adrenergic, beta-2; Signal Transduction; Transfection | 2000 |
beta(1)-Adrenoceptors compensate for beta(3)-adrenoceptors in ileum from beta(3)-adrenoceptor knock-out mice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Genotype; Ileum; In Vitro Techniques; Isoproterenol; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Pindolol; Propranolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta1/beta2-adrenoceptor knockout mice. Obligatory role of beta1-adrenoceptors for putative beta4-adrenoceptor pharmacology.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atrial Function; Binding, Competitive; Bucladesine; Dose-Response Relationship, Drug; Female; Genotype; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Membranes; Mice; Mice, Knockout; Myocardial Contraction; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sinoatrial Node; Tritium | 2001 |
Activation of 5-HT(1B/1D) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study.
Topics: Animals; Dopamine; Male; Microdialysis; Nucleus Accumbens; Pindolol; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Time Factors; Ventral Tegmental Area | 2001 |
Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Behavior, Animal; Brain; Carrier Proteins; Citalopram; Female; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Pindolol; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists | 2001 |
Consequences of labetalol administration on myocardial beta adrenergic receptors in the brain dead pig.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Brain Death; Heart; Hemodynamics; In Vitro Techniques; Kinetics; Labetalol; Myocardium; Pindolol; Receptors, Adrenergic, beta; Swine | 2000 |
The Ile164 beta(2)-adrenoceptor polymorphism alters salmeterol exosite binding and conventional agonist coupling to G(s).
Topics: Adrenergic beta-Agonists; Albuterol; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Genotype; Humans; Iodine Radioisotopes; Isoproterenol; Metaproterenol; Pindolol; Polymorphism, Genetic; Radioligand Assay; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; Terbutaline | 2001 |
Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Male; Oxadiazoles; Pindolol; Piperazines; Potassium; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Ventral Tegmental Area | 2001 |
Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis.
Topics: Acetic Acid; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colitis, Ulcerative; Colon; Dose-Response Relationship, Drug; Ethanolamines; Female; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Peroxidase; Pindolol; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-3; RNA, Messenger | 2002 |
Methiothepin attenuates gastric secretion and motility effects of vagal stimulants at the dorsal vagal complex.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Acid; Gastrointestinal Motility; Glutamic Acid; Kainic Acid; Male; Methiothepin; Methysergide; Pindolol; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin Antagonists; Solitary Nucleus; Time Factors; Vagus Nerve | 2002 |
Altered expression of autonomic neurotransmitter receptors and proliferative responses in lymphocytes from a chronic mild stress model of depression: effects of fluoxetine.
Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Second-Generation; Autonomic Nervous System; B-Lymphocytes; CD4-CD8 Ratio; Cell Division; Chronic Disease; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Female; Fluoxetine; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Mitogens; Muscarinic Antagonists; Pindolol; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Muscarinic; Stress, Psychological; T-Lymphocytes; Tritium | 2002 |
Serotonergic control of cerebellar mossy fiber activity by modulation of signal transfer by rat pontine nuclei neurons.
Topics: Animals; Cinanserin; Electrophysiology; Nerve Fibers; Pindolol; Pons; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission | 2002 |
Evidence that the anorexia induced by lipopolysaccharide is mediated by the 5-HT2C receptor.
Topics: Adrenergic beta-Antagonists; Aminopyridines; Animals; Anorexia; Dopamine Antagonists; Dose-Response Relationship, Drug; Indoles; Lipopolysaccharides; Male; Metoclopramide; Pindolol; Piperidones; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiro Compounds; Sulfonamides | 2003 |
Hypothalamic-pituitary-thyroid axis and sympathetic nervous system involvement in hyperthermia induced by 3,4-methylenedioxymethamphetamine (Ecstasy).
Topics: 3,4-Methylenedioxyamphetamine; Adrenergic alpha-Antagonists; Animals; Drug Interactions; Fever; Hypophysectomy; Hypothalamo-Hypophyseal System; Male; Muscle, Skeletal; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Pindolol; Prazosin; Rats; Rats, Sprague-Dawley; Rectum; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Thyroid Gland; Thyroxine | 2003 |
Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Bicuculline; Fluorobenzenes; GABA-A Receptor Antagonists; Glutamic Acid; Indoles; Lidocaine; Male; Patch-Clamp Techniques; Phenols; Pindolol; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors | 2004 |
Characterization of mexiletine as an antagonist of beta-adrenoceptor in Chinese hamster ovary cells expressing cloned human beta-adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Lidocaine; Mexiletine; Pindolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Transfection | 2004 |
ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Aorta, Thoracic; Binding Sites; Bupranolol; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanolamines; Imidazoles; Male; Muscle, Smooth, Vascular; Phenylephrine; Pindolol; Prazosin; Propanolamines; Propranolol; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-3; Tritium; United Kingdom; Vasoconstriction | 2004 |
Site-directed mutagenesis of the rat beta1-adrenoceptor. Involvement of Tyr356 (7.43) in (+/-)cyanopindolol but not (+/-)[125Iodo]cyanopindolol binding.
Topics: Adrenergic beta-Antagonists; Animals; Iodine Radioisotopes; Models, Molecular; Mutagenesis, Site-Directed; Pindolol; Protein Binding; Protein Conformation; Radioligand Assay; Rats; Receptors, Adrenergic, beta-1; Tyrosine | 2004 |
Functional responses of human beta1 adrenoceptors with defined haplotypes for the common 389R>G and 49S>G polymorphisms.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cells, Cultured; Cyclic AMP; DNA, Complementary; Down-Regulation; Genotype; Haplotypes; Humans; Iodine Radioisotopes; Isoproterenol; Kidney; Ligands; Pindolol; Polymorphism, Genetic; Receptors, Adrenergic, beta-1 | 2004 |
Modulatory effects on myocardial physiology induced by an anti-Trypanosoma cruzi monoclonal antibody involve recognition of major antigenic epitopes from beta1-adrenergic and M2-muscarinic cholinergic receptors without requiring receptor cross-linking.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antibodies, Monoclonal; Antibodies, Protozoan; Binding, Competitive; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Epitopes; Immunoglobulin Fab Fragments; In Vitro Techniques; Iodine Isotopes; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Myocardial Contraction; Pindolol; Quinuclidinyl Benzilate; Radioimmunoassay; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Adrenergic, beta-1; Titrimetry; Trypanosoma cruzi | 2004 |
Impairment of the low-affinity state beta1-adrenoceptor-induced relaxation in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Immunohistochemistry; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pindolol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta-1 | 2004 |
Evidence for pleiotropic signaling at the mouse beta3-adrenoceptor revealed by SR59230A [3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate].
Topics: 3T3 Cells; Adipocytes; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; CHO Cells; Cricetinae; Cyclic AMP; Dioxoles; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Ileum; Mice; Pindolol; Propanolamines | 2005 |
Evidence for the presence of beta-3-adrenoceptors mediating relaxation in the human oviduct.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adult; Dose-Response Relationship, Drug; Ethanolamines; Fallopian Tubes; Female; Humans; In Vitro Techniques; Isoproterenol; Middle Aged; Muscle Relaxation; Pindolol; Propranolol; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Beta-adrenoceptor-mediated vascular relaxation in spontaneously hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Pindolol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Tetrahydronaphthalenes | 2005 |
Low-affinity state beta1-adrenoceptor-induced vasodilation in SHR.
Topics: Adrenergic beta-1 Receptor Agonists; Alprenolol; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Enalapril; Losartan; Male; Muscle Relaxation; Pindolol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta-1; Vasodilation | 2005 |
Positive inotropic and lusitropic effects mediated via the low-affinity state of beta1-adrenoceptors in pithed rats.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Decerebrate State; Humans; Male; Myocardial Contraction; Pindolol; Prenalterol; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1 | 2005 |
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.
Topics: Adenylyl Cyclases; Alanine; Arrestins; Aspartic Acid; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Epinephrine; G-Protein-Coupled Receptor Kinase 1; Green Fluorescent Proteins; Humans; Isoproterenol; Kinetics; Mutation; Phosphorylation; Pindolol; Protein Structure, Tertiary; Protein Transport; Receptors, Adrenergic, beta-2; Serine; Time Factors; Transfection | 2006 |
5-HT-stimulated [35S]guanosine-5'-O-(3-thio)triphosphate binding as an assay for functional activation of G proteins coupled with 5-HT1B receptors in rat striatal membranes.
Topics: Animals; Binding, Competitive; Corpus Striatum; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Oxadiazoles; Pindolol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Agents; Sulfur Radioisotopes; Tryptamines | 2006 |
Potential involvement of a propranolol-insensitive atypical beta-adrenoceptor the vasodilator effect of cyanopindolol in the human pulmonary artery.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Bupranolol; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; In Vitro Techniques; Male; Middle Aged; Pindolol; Pulmonary Artery; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Serotonin 5-HT2 Receptor Antagonists; Vasoconstriction; Vasodilation; Vasodilator Agents | 2006 |
5-HT excites globus pallidus neurons by multiple receptor mechanisms.
Topics: Animals; Cations; Electrophysiology; Excitatory Postsynaptic Potentials; Globus Pallidus; In Vitro Techniques; Ion Channels; Male; Neurons; Patch-Clamp Techniques; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Synapses; Synaptic Transmission | 2008 |
Structure of a beta1-adrenergic G-protein-coupled receptor.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Amino Acid Motifs; Animals; Binding Sites; Crystallization; Crystallography, X-Ray; Ligands; Models, Molecular; Mutant Proteins; Mutation; Pindolol; Propanolamines; Protein Conformation; Receptors, Adrenergic, beta-1; Thermodynamics; Turkeys | 2008 |
Preservation of the positive lusitropic effect of beta-adrenoceptors stimulation in diabetic cardiomyopathy.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Colforsin; Diabetes Complications; Diabetes Mellitus, Experimental; Echocardiography; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Phentolamine; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2008 |
Influence of beta2-adrenoceptor gene polymorphisms on beta2-adrenoceptor expression in human lung.
Topics: Female; Gene Expression; Genotype; Humans; Lung; Male; Pindolol; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Binding; Radioligand Assay; Receptors, Adrenergic, beta-2 | 2010 |
Structural insights into conformational stability of wild-type and mutant beta1-adrenergic receptor.
Topics: Adrenergic beta-1 Receptor Agonists; Amino Acid Substitution; Animals; Models, Molecular; Mutant Proteins; Mutation; Norepinephrine; Pindolol; Protein Stability; Protein Structure, Secondary; Receptors, Adrenergic, beta-1; Salts; Transition Temperature; Turkeys | 2010 |
Engineering an ultra-thermostable β(1)-adrenoceptor.
Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Disulfides; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Pindolol; Protein Binding; Protein Conformation; Protein Engineering; Protein Stability; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, G-Protein-Coupled; Temperature; Turkey; Zinc | 2011 |
Tachyphylaxis to the sumatriptan-induced contractile effect in the human uterine artery but not in human cerebral blood vessels: pharmacological demonstration of the 5-HT(1B) receptor functionality loss.
Topics: Adult; Basilar Artery; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Middle Aged; Middle Cerebral Artery; Muscle, Smooth, Vascular; Pindolol; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sumatriptan; Tachyphylaxis; Time Factors; Uterine Artery | 2012 |
Structural basis for molecular recognition at serotonin receptors.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Dihydroergotamine; Ergotamine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Lysergic Acid Diethylamide; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis; Norfenfluramine; Pindolol; Propranolol; Protein Conformation; Protein Folding; Protein Structure, Secondary; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2013 |
5-HT1B receptor modulation of the serotonin transporter in vivo: studies using KO mice.
Topics: Animals; Fluvoxamine; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pindolol; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2014 |
The 2.1 Å resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor.
Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Cell Membrane; Crystallography, X-Ray; Models, Molecular; Mutation; Pindolol; Protein Binding; Protein Conformation; Protein Stability; Receptor, Adenosine A2A; Receptors, Adrenergic, beta-1; Sodium; Temperature; Turkeys | 2014 |
Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity.
Topics: Actins; Aggression; Animals; Animals, Newborn; Brain; Choice Behavior; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Doxycycline; Gene Expression Regulation, Developmental; Impulsive Behavior; Iodine Isotopes; Mice; Mice, Transgenic; Pindolol; Piperazines; Protein Binding; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Antagonists | 2015 |
Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor.
Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Humans; Pindolol; Protein Binding; Protein Structure, Secondary; Receptors, Adrenergic, beta-1; Structure-Activity Relationship; Turkey | 2015 |
Nebivolol ameliorates asymmetric dimethylarginine-induced vascular response in rat aorta via β3 adrenoceptor-mediated mechanism.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-3 Receptor Antagonists; Animals; Aorta; Arginine; Butoxamine; Enzyme Inhibitors; In Vitro Techniques; Nebivolol; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Pindolol; Rats; Receptors, Adrenergic, beta-3 | 2016 |
A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors.
Topics: Animals; Animals, Newborn; Anxiety; Autoreceptors; Depression; Disease Models, Animal; Exploratory Behavior; Food Preferences; Hippocampus; Iodine Isotopes; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pindolol; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2016 |
Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Deep Brain Stimulation; Fluoxetine; Hippocampus; Iodine Radioisotopes; Pindolol; Prefrontal Cortex; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tritium | 2018 |