cyanides and fk 866
cyanides has been researched along with fk 866 in 4 studies
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Björkling, F; Christensen, MK; Jäättelä, M; Jensen, PB; Nielsen, SJ; Olesen, UH; Sehested, M | 1 |
| Berglund, A; Larsson, R; Nygren, P; von Heideman, A | 1 |
| Björkling, F; Christensen, MK; Fristrup, P; Garten, A; Imai, S; Jensen, PB; Kiess, W; Nielsen, SJ; Olesen, UH; Petersen, JG; Sehested, M; Thougaard, AV; Yoshino, J | 1 |
| Cahill, DP; Kirtane, AR; Kiyokawa, J; Lee, CK; Li, M; Lopes, A; Nagashima, H; Tirmizi, ZA; Traverso, G; Wakimoto, H | 1 |
Trials
1 trial(s) available for cyanides and fk 866
| Article | Year |
|---|---|
Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data.
Topics: Acrylamides; Aged; Clinical Trials, Phase I as Topic; Cyanides; Dose-Response Relationship, Drug; Drug Administration Schedule; Fatigue; Female; Guanidines; Humans; Male; Meta-Analysis as Topic; Middle Aged; NAD; Nausea; Neoplasms; Nicotinamide Phosphoribosyltransferase; Piperidines; Thrombocytopenia; Treatment Outcome; Vomiting | 2010 |
Other Studies
3 other study(ies) available for cyanides and fk 866
| Article | Year |
|---|---|
Anticancer agent CHS-828 inhibits cellular synthesis of NAD.
Topics: Acrylamides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyanides; Dose-Response Relationship, Drug; Guanidines; Humans; Lung Neoplasms; NAD; Piperidines; Signal Transduction | 2008 |
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
Topics: Acrylamides; Animals; Antineoplastic Agents; Binding Sites; Binding, Competitive; Catalytic Domain; Cell Line, Tumor; Cyanides; Cytokines; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Guanidines; HCT116 Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Models, Molecular; Mutation; Neoplasms; Nicotinamide Phosphoribosyltransferase; Piperidines; Protein Conformation; Time Factors; Transfection; Xenograft Model Antitumor Assays | 2010 |
Local Targeting of NAD
Topics: Acrylamides; Animals; Autophagy; B7-H1 Antigen; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Movement; Cyanides; Cytokines; Delayed-Action Preparations; Drug Carriers; Glioblastoma; Guanidines; Humans; Injections, Intralesional; Macrophages; Membrane Proteins; Mice; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Polymers; RNA, Messenger; Signal Transduction; Tumor Microenvironment; Up-Regulation | 2020 |