cyanates has been researched along with methyl isocyanate in 277 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 140 (50.54) | 18.7374 |
| 1990's | 66 (23.83) | 18.2507 |
| 2000's | 28 (10.11) | 29.6817 |
| 2010's | 37 (13.36) | 24.3611 |
| 2020's | 6 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, CK | 1 |
| Dhara, R | 1 |
| Malini, RP; Meshram, GP; Rao, KM | 1 |
| Aoki, K; Lee, MS; Tamura, N | 1 |
| Chandarana, JP; Dalal, N; Gopalani, JP; Kamat, SR; Kolhatkar, VP; Naik, M; Patel, MH; Pradhan, PV; Taskar, SP; Vaidya, PR | 1 |
| Jeevaratnam, K; Vaidyanathan, CS; Vidya, S | 2 |
| Agarwal, GS; Gopalan, N; Kaushik, MP; Raghuveeran, CD; Venkateswaran, KS; Vijayaraghavan, R | 1 |
| Agarwal, DK; Bose, M | 1 |
| Jeevaratnam, K; Vaidyanathan, CS | 2 |
| Rennie, J | 1 |
| Baillie, TA; Guest, I; Varma, DR | 1 |
| Alarie, Y; Ferguson, JS | 1 |
| Chandra, H; Kamat, SR; Narayanan, PS; Sharma, S; Sriramachari, S; Vijayan, VK | 1 |
| Bhattacharya, R; Jeevaratnam, K; Sugendran, K; Vaidyanathan, CS | 1 |
| Chandra, H; Jadhav, RK; Rao, GJ; Saraf, AK; Sharma, VK; Sriramachari, S | 2 |
| Dutta, KK; Dwivedi, PD; Mishra, A; Mishra, J; Ray, PK; Sinha, M; Verma, AS | 1 |
| Das, BC | 1 |
| Eckert, WG | 1 |
| Costa, DL; Fitzgerald, S; Tepper, JS; Weber, MF; Wiester, MJ | 1 |
| Dixit, R; Gupta, GS; Kaw, JL; Naqvi, SH; Ray, PK | 1 |
| Das, SN; Dutta, KK; Paul, BN; Ray, PK; Saxena, AK; Sinha, M | 1 |
| Jeevaratnam, K; Selvamurthy, W | 1 |
| Jacobs, PA | 1 |
| Agrawal, D; Dutta, KK; Gupta, GS; Ray, PK; Shukla, JS | 1 |
| Anderson, D; Beech, L; Butler, WH; Goyle, S; Phillips, BJ; Tee, A | 2 |
| Makhijani, AB; Mehta, AS; Mehta, PS; Mehta, SJ | 1 |
| Bhattacharya, K; Chandorkar, M; Goswami, HK; Goswami, R; Parmar, D; Patidar, SL; Sengupta, LK; Sengupta, S; Sharma, PN; Vaidyanath, G | 1 |
| Baillie, TA; Grillo, MP; Han, DH; Pearson, PG; Rashed, MS; Slatter, JG | 1 |
| Guest, I; Mulay, S; Smith, S; Varma, DR | 1 |
| Jayaraman, KS | 1 |
| Ajwani, MK; Andersson, N; Ashiru, K; Mackenzie, CD; Mahashabde, S; Mehra, V; Muir, MK; Tiwari, MK | 1 |
| Ghosh, BB; Ghosh, S; Maity, S; Roy, A; Sengupta, S; Sharma, A; Talukder, G | 1 |
| Alarie, Y; Brown, WE; Kennedy, AL; Stock, MF | 1 |
| Andersson, N | 1 |
| Mangla, B | 1 |
| Darbari, BS; Mehrotra, Y; Misra, NP; Pandey, VP; Sankaran, K; Vijayan, VK | 1 |
| Kar, RN; Khan, KA; Sethi, N | 1 |
| Li, FJ; Segal, A; Solomon, JJ | 1 |
| Dayal, R; Sethi, N; Singh, RK | 1 |
| Mathews, AJ; Nagai, K; Olson, JS; Renaud, JP; Rohlfs, RJ; Tame, J | 1 |
| Kumar, P; Pant, SC; Sachan, AS; Srivastava, RK; Vijayaraghavan, R | 1 |
| Bucher, JR; Hildebrandt, PK; Sauer, RM; Seely, JC; Uraih, LC | 1 |
| Arora, U; Vijayaraghavan, R | 1 |
| Carter, JT | 1 |
| Andersson, N; Brown, RB; Kerr Muir, M; Mehra, V; Mittal, PC; Purnell, CJ; Salmon, AG; Wells, CJ | 1 |
| Harding, JJ; Rixon, KC | 1 |
| Dinsdale, D; Nemery, B; Sparrow, S | 1 |
| Andersson, N; Gassert, T; Kerr Muir, M; MacKenzie, C; Salmon, AG | 1 |
| Bucher, JR; Germolec, DR; Luster, MI; Silver, MT; Tucker, AN; Vore, SJ | 1 |
| Costa, DL; Tepper, JS; Watkinson, WP; Weber, MF; Wiester, MJ | 1 |
| Bhattacharya, BK; Chattopadhyay, DP; Malhotra, RC | 1 |
| Rosencranz, A; Tyagi, YK | 1 |
| Jasanoff, S | 1 |
| Dodd, DE | 1 |
| Tachakra, SS | 1 |
| Allen, JW; Caspary, WJ; Haworth, S; Ivett, J; Kligerman, A; Luke, CA; Mason, JM; Myhr, B; Shelby, MD; Tice, RR | 1 |
| Dwivedi, PC; Raizada, JK | 2 |
| Maskati, QB | 2 |
| Jeevarathinam, K; Mukhopadhyay, S; Ray, US; Selvamurthy, W; Thakur, L | 1 |
| Kaushik, MP; Kumar, P; Pant, SC; Sachan, AS; Srivastava, RK; Vijayaraghavan, R | 1 |
| Tice, RR | 1 |
| Meshram, GP; Rao, KM | 3 |
| Bucher, JR | 1 |
| Alarie, Y; Ferguson, JS; Varma, DR | 2 |
| Alarie, Y; Brown, WE; Ferguson, JS; Kennedy, AL; Stock, MF | 1 |
| Bhattacharya, BK; Jaiswal, DK; Sharma, SK | 1 |
| Agarwal, GS; Gandhe, BR; Gopalan, N; Kaushik, MP; Ramachandran, PK; Shinde, SK; Sriramachari, S; Suryanarayana, MV; Venkateswaran, KS; Vijayaraghavan, R | 1 |
| Andersson, N; Kerr Muir, M; Mehra, V; Salmon, AG | 1 |
| Chandra, H; Gupta, BN; Kumar, P; Kumar, S; Mahendra, PN; Mathur, AK; Mathur, N; Pangtey, BS; Rastogi, SK; Seth, RK | 1 |
| Chandra, S; Gupta, BN; Husain, T; Kumar, A; Rastogi, SK; Ray, PK | 1 |
| Athar, M; Behari, JR; Bharti, RS; Dwivedi, RS; Gupta, BN; Hasan, SK; Misra, M; Ray, PK; Singh, A; Srivastava, RC | 1 |
| Gupta, BN; Nagle, SL; Ray, PK; Saxena, AK; Singh, KP; Singh, R; Srivastav, RK; Tewari, SP | 1 |
| Dutta, KK; Gupta, GS; Joshi, A; Mishra, A; Ray, PK; Tandon, GS | 1 |
| Dutta, KK; Gupta, GS; Jaffery, FN; Mishra, A; Ray, PK; Viswanathan, PN | 1 |
| Dutta, KK; Gupta, GS; Kumar, VS; Mishra, A; Ray, PK | 1 |
| Das, SN; Dutta, KK; Dwivedi, PD; Gupta, GS; Mishra, A; Ray, PK | 1 |
| Dutta, KK; Gupta, GS; Mishra, A; Nagale, SL; Ray, PK; Saxena, AK; Singh, KP; Zaidi, SI | 1 |
| Gupta, BN; Khan, WA; Misra, UK; Nag, D; Nath, P; Ray, PK | 1 |
| Ennever, FK; Rosenkranz, HS | 1 |
| Batni, G; Bhargava, DK; Jain, SK; Misra, NP; Tiwari, UC; Verma, A; Vijayan, VK | 1 |
| Asthana, BS; Gaur, KJ; Jain, SC; Manoria, PC; Misra, NP; Pathak, R; Sharma, KN; Tripathi, BM; Trivedi, HH; Yesikar, SS | 1 |
| Dave, AA; Kamat, SR; Kolhatkar, VP; Mahashur, AA; Patel, MH | 1 |
| Gaur, KJ; Sharma, PN | 1 |
| Sethi, BB; Sharma, M; Singh, H; Trivedi, JK | 1 |
| Isaac, MK; Murthy, RS | 1 |
| Bharucha, EP; Bharucha, NE | 1 |
| Balsara, B; Bhide, S; Bhisey, AN; Darbari, BS; Deo, MG; Gangal, S; Gulwani, B; Maru, GB; Somasundaram, R | 1 |
| Darbari, BS; Kanhere, S; Shrivastava, AK | 1 |
| Agarwal, SS; Daniel, CS; Das, SK; Mathur, BB; Siddiqui, P; Singh, AK | 1 |
| Kaushik, MP; Vijayaraghavan, R | 1 |
| Kaushik, MP; Kumar, P; Pant, SC; Sachan, AS; Sharma, SK; Srivastava, RK; Vijayaraghavan, R | 1 |
| Acharya, VN; Bhalerao, RA; Naik, SR; Potnis, AV | 1 |
| Bucher, JR; Germolec, DR; Luster, MI; Silver, MT; Thomas, PT; Tucker, AN; Vore, SJ | 1 |
| Haworth, S; Ivett, J; Mason, JM; Valencia, R; Zeiger, E | 1 |
| Boorman, GA; Brown, R; Bucher, JR; Gupta, BN; Uraih, LC | 1 |
| Pant, SC; Srivastava, RK; Vijayaraghavan, R | 1 |
| Acharya, VN; Bhalerao, RA; Kowli, SS; Mahashur, AA; Mehta, AC; Naik, SR; Nazareth, H; Potnis, AV; Shah, S | 2 |
| Irani, SF; Mahashur, AA | 1 |
| Hinduja, IN; Raval, MY; Shilotri, NP | 1 |
| Berardinelli, SP; Moyer, ES | 2 |
| Calovini, L; Gaind, VS; Nazar, MA; Wu, WS | 1 |
| Bucher, JR; Gupta, BN; Hall, LB; Stefanski, SA | 1 |
| Dodd, DE; Fowler, EH | 3 |
| Dodd, DE; Fowler, EH; Pritts, IM; Snellings, WM | 1 |
| Dodd, DE; Fowler, EH; Frank, FR; Milton, RM; Troup, CM | 1 |
| Adkins, B; Bucher, JR; Gupta, BN; Schwetz, BA; Thompson, M | 1 |
| Boorman, GA; Bucher, JR; Canipe, J; Hong, HL | 1 |
| Adkins, B; Harris, M; Moorman, M; Schwetz, BA; Sloane, R | 1 |
| Varma, DR | 1 |
| Alarie, Y; Ferguson, JS; Schaper, M; Stock, MF; Weyel, DA | 2 |
| Gangal, S; Kamat, SR; Karol, MH; Rubanoff, BF; Taskar, S | 1 |
| Alarie, Y; Conner, MK; Ferguson, JS; Rubinson, HF; Stock, MF | 1 |
| Dodd, DE; Kolb, WP; Savary, JR; Tamerius, JD; Troup, CM | 1 |
| Dodd, DE; Fowler, EH; Frank, FR; Troup, CM | 1 |
| Dodd, DE; Fedde, MR; Fowler, EH; Troup, CM | 1 |
| Maginniss, LA; Szewczak, JM; Troup, CM | 1 |
| Dodd, DE; Fowler, EH; Troup, CM | 1 |
| Adkins, B; Dement, JM; O'Connor, RW | 1 |
| Brown, WE; Cairns, J; Cedel, TE; Green, AH | 1 |
| Adkins, B; Bucher, JR; Gupta, BN; Jameson, CW; Schwetz, BA; Thigpen, JE; Thompson, M | 1 |
| Boorman, GA; Bucher, JR; Gupta, BN; Uraih, LC | 1 |
| Boorman, GA; Bucher, JR; Gupta, BN; Hall, LB; Stefanski, SA; Uraih, LC | 1 |
| Boorman, GA; Bucher, JR; Gupta, BN; Mitsumori, K; Talley, FA; Uraih, LC | 1 |
| Bucher, JR; Costa, DL; Fitzgerald, S; Ménache, MG; Stevens, MA | 1 |
| Buettner, LC; Hsu, SS; James, JT | 1 |
| Farquhar, D; Newman, RA | 1 |
| Parikh, CK | 1 |
| Boorman, GA; Bucher, JR; Gupta, BN; Mitsumori, K | 1 |
| Greenberg, HL; Halperin, WE; Ott, MG; Rinsky, RA | 1 |
| Baron, RL; Dodd, DE; Fowler, EH; Pritts, IM; Snellings, WM | 1 |
| Salmon, AG | 2 |
| Anderson, D; Blowers, SD; Nemery, B | 1 |
| Caspary, WJ; Myhr, B | 1 |
| Goswami, HK | 1 |
| Kulling, PE; Lorin, HG | 1 |
| Allen, JW; Campbell, JA; Erexson, GL; Kligerman, AD; Shelby, MD | 1 |
| Luke, CA; Shelby, MD; Tice, RR | 1 |
| Reinberg, A; Smolensky, MH | 1 |
| Sutcliffe, M | 1 |
| Aydelotte, CL | 1 |
| Zaidi, SH | 1 |
| Ippen, H; Proksch, E | 1 |
| Marwick, C | 2 |
| Curran, WJ | 1 |
| Diller, WF | 1 |
| Das, JJ | 1 |
| Dwivedi, PC; Mittal, PC; Raizada, JK; Saini, VK | 1 |
| Andersson, N; Kerr Muir, M; Salmon, AG | 1 |
| Dinsdale, D; Nemery, B; Ray, DE; Sparrow, S | 1 |
| Ketcham, NH; Neff, JE | 1 |
| Andersson, N; Mehra, V; Muir, MK | 1 |
| Alarie, Y; Brown, WE; Kennedy, AL; Singh, G | 1 |
| Misra, NP; Sankaran, K; Sharma, SK; Vijayan, VK | 1 |
| Jeevaratnam, K; Sriramachari, S | 3 |
| Mukerjee, M | 1 |
| Bose, M; Dutta, KK; Jha, BS | 1 |
| Wax, PM | 1 |
| Guest, I; Varma, DR | 2 |
| Chandra, H; Jadhav, RK; Rao, GJ; Saraf, AK; Sharma, VK; Sriramachari, S; Vairamani, M | 1 |
| Jeevaratnam, K; Vidya, S | 1 |
| Jeevaratnam, K; Sugendran, K; Vaidyanathan, CS | 1 |
| Bajpai, R; Dutta, KK; Gupta, GS; Kaw, JL; Ray, PK | 1 |
| Baillie, TA; Jochheim, CM | 1 |
| Bose, M; Dutta, KK; Jha, BS; Vachhrajani, KD | 1 |
| Bajaj, JS; Madan, R; Misra, A; Rajalakshmi, M | 1 |
| Arora, U; Mathur, R; Sugendran, K; Vijayaraghavan, R | 1 |
| Farnsworth, PN; Kuckel, CL; Lambooy, PK; Lubit, BW | 1 |
| Jeevaratnam, K | 1 |
| Avashia, B; Battigelli, MC; Morgan, WK; Reger, RB | 1 |
| Nemery, B | 1 |
| Sankaran, K; Vijayan, VK | 1 |
| Acquilla, S; Cullinan, P; Dhara, VR | 1 |
| Garner, P | 1 |
| Mayon-White, RT | 1 |
| Chandra, H; Sriramachari, S | 1 |
| Kalita, J; Misra, UK | 1 |
| Acquilla, S; Cullinan, P | 1 |
| Service, RF | 1 |
| Beckett, WS | 1 |
| Penketh, PG; Sartorelli, AC; Shyam, K | 1 |
| Dikshit, RP; Kanhere, S | 1 |
| Henriks-Eckerman, ML; Rosenberg, C; Välimaa, J | 1 |
| Angerer, J; Käfferlein, HU | 1 |
| Abu-Sharkh, BF; Badawi, HM; Förner, W; Oloriegbe, YS | 1 |
| Acquilla, SD; Cullinan, P; Dhara, R; Dhara, VR | 1 |
| Sharma, DC | 2 |
| Ekman, J; Levin, JO; Lindahl, R; Ostin, A; von Zweigbergk, P | 1 |
| Henneken, H; Karst, U; Levin, JO; Lindahl, R; Ostin, A; Vogel, M | 1 |
| EBEN, A; KIMMERLE, G | 1 |
| Holleran, S; Padmanabhan, VT; Ramakrishnan, R; Ranjan, N; Sarangi, S; Varma, DR | 1 |
| Baumann, RP; Brent, TP; Penketh, PG; Remack, JS; Sartorelli, AC; Shyam, K | 1 |
| Chvalová, D; Mráz, J; Nohová, H; Simek, P; Smigolová, P | 1 |
| Crabb, C | 1 |
| Padma, TV | 1 |
| Broughton, E | 1 |
| Birmelin, M; Dodidou, P; Grüttner, J; Kerger, H; Passani-Kruppa, D; Volz, A; Waschke, KF | 1 |
| Boutin, M; Lesage, J; Ostiguy, C; Pauluhn, J | 1 |
| Baumann, RP; Penketh, PG; Sartorelli, AC; Seow, HA; Shyam, K | 1 |
| Hayen, H; Henneken, H; Karst, U; Vogel, M | 1 |
| Bhattacharya, SK; Fernandez, C; Hom, GG; Hom, LG | 1 |
| Jeffrey, J; Kuo, T; Sztain, J | 1 |
| Satyanand, T | 1 |
| Pigneux, A | 1 |
| Bhargava, A; Gupta, S; Jain, SK; Maudar, KK; Mishra, PK; Raghuram, GV; Tiwari, S; Upadhyaya, R | 1 |
| Löfstedt, H; Lundholm, C; Seldén, AI; Svartengren, M; Westberg, H | 1 |
| Chauhan, C; Dabadghao, S; Desikan, P; Gupta, D; Jain, A; Jain, SK; Maudar, KK; Mishra, PK; Mittra, I; Modi, GK | 1 |
| Akhtar, N; Bhargava, A; Jatawa, SK; Khan, S; Maudar, KK; Mishra, PK; Raghuram, GV; Tiwari, A | 1 |
| Bucht, A; Gustafsson, A; Koch, BL; Svensson-Elfsmark, L | 1 |
| Banerjee, S; Jain, SK; Maudar, KK; Mishra, PK; Pathak, N; Samarth, RM | 1 |
| Gadag, VG; Katgara, D; Mulay, S; Pal, RK; Sarangi, S; Varma, DR; Zaidi, T | 1 |
| Bhargava, A; Dabadghao, S; Desikan, P; Jain, A; Maudar, KK; Mishra, PK; Pathak, N; Punde, RP | 1 |
| Bagla, P | 1 |
| Jain, D; Jain, SK; Mishra, PK; Pandey, H; Panwar, H; Pathak, N; Raghuram, GV | 1 |
| Patil, RR | 1 |
| Bhargava, A; Desikan, P; Jain, A; Maudar, KK; Mishra, PK; Pathak, N; Shrivastava, R; Varshney, S | 1 |
| Ahirwar, AK; Banerjee, S; Jain, D; Jain, SK; Khan, S; Maudar, KK; Mishra, PK; Panwar, H; Pathak, N; Raghuram, GV | 1 |
| De, S | 1 |
| Ganesh, N; Malla, TM; Sah, NK; Senthilkumar, CS | 2 |
| Mishra, PK | 1 |
| Havens, J; Spicer, T; Walker, H | 1 |
| Song, LQ; Wang, XY; Yu, Y | 1 |
| Ganesh, N; Sah, NK; Senthilkumar, CS | 2 |
| Senthilkumar, CS | 1 |
| Gandhi, P; Maudar, KK; Samarth, RM | 1 |
| Banerjee, S; Bhargava, A; Jain, D; Khan, S; Mishra, PK; Panwar, H; Pathak, N; Raghuram, GV | 1 |
| Shrivastava, R; Singh, P; Tripathi, M; Yasir, M | 1 |
| Hebert, VR; Lu, Z; Miller, GC | 1 |
| Cincotta, DJ; Ghazvinian, R; He, Y; Ji, W; Li, Y; Min, W; Praggastis, A; Rice, KP; Yang, M; Zhou, HJ | 1 |
| Hebert, VR; LePage, JT; Miller, GC; Woodrow, JE | 1 |
| Howard, S | 1 |
| Mishra, PK; Raghuram, GV | 1 |
| Akhter, S; Ganesh, N; Malla, TM; Sah, NK; Senthilkumar, CS | 2 |
| Bhargava, A; Bunkar, N; Khare, NK; Mishra, PK; Raghuram, GV | 1 |
| Bose, P; Dubey, A; Gurjar, VS; Shrivastava, R; Tripathi, MK; Yasir, M | 1 |
| Jatawa, SK; Khan, I; Sachdeva, M; Senthilkumar, CS; Singh, H; Tiwari, A; Upadhyay, N | 1 |
| Ganguly, BB; Mandal, S | 1 |
| Ganguly, BB; Kadam, NN; Mandal, S | 1 |
| Abbi, R; Banerjee, N; Ganguly, BB; Kadam, NN; Mandal, S | 1 |
| Brenner, M; Chen, Z; Desai, V; Jing, JC; Mahon, SB; Miao, Y; Veress, LA; White, CW | 1 |
| Croutch, CR; Logue, BA; Manandhar, E; Pay, AL; Peters, E; Rioux, JS; Sosna, W; Veress, LA; White, CW; Zhang, Z | 1 |
| Champagne, PA; Hara, K; Hashimoto, H; Hirayama, Y; Houk, KN; Kishimoto, S; Tang, Y; Watanabe, K | 1 |
| Croutch, CR; Garlick, RB; Peters, E; Rancourt, RC; Rioux, JS; Sosna, W; Veress, LA; White, CW | 1 |
| Ganguly, BB | 1 |
| Anantharam, P; Bloomquist, LA; Bratcher, PE; Croutch, CR; Nick, HJ; Peters, E; Rioux, JS; Sosna, W; Tuttle, RS; Veress, LA; White, CW | 1 |
| Allen, BC; Blessinger, T; Davis, JA; Gift, JS; Olszyk, L; Shao, K; Wheeler, MW | 1 |
| Bagchi, P; Blount, BC; Chambers, DM; De Jesús, VR; Kenwood, BM; Zhang, L; Zhu, W | 1 |
| Ganguly, BB; Ganguly, S; Kadam, NN | 1 |
| Donkor, AB; Gyamfi, OA; Logue, BA; Nick, HJ; Rioux, JS; Veress, LA; White, CW | 1 |
16 review(s) available for cyanates and methyl isocyanate
| Article | Year |
|---|---|
Health effects of the Bhopal gas leak: a review.
Topics: Accidents, Occupational; Air Pollutants; Animals; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates; Poisoning | 1992 |
Bhopal tragedy's health effects. A review of methyl isocyanate toxicity.
Topics: Accidents, Occupational; Cyanates; Gas Poisoning; Humans; India; Isocyanates | 1990 |
Some international law aspects of the Bhopal disaster.
Topics: Accidents, Occupational; Cyanates; Disasters; Humans; India; Insurance, Liability; International Cooperation; Isocyanates; Public Policy | 1988 |
The Bhopal disaster and the right to know.
Topics: Accidents, Occupational; Confidentiality; Cyanates; Disasters; Humans; India; Isocyanates; Public Policy; Risk Factors | 1988 |
Toxicology of methyl isocyanate.
Topics: Animals; Cyanates; Isocyanates | 1988 |
Methyl isocyanate: a review of health effects research since Bhopal.
Topics: Accidents, Occupational; Animals; Chemical Industry; Cyanates; Disasters; Environmental Exposure; Follow-Up Studies; Hemoglobins; Humans; Immunity; India; Isocyanates; Lung; Mutagens; Reproduction | 1987 |
Environmental release of chemicals and reproductive ecology.
Topics: Abortion, Spontaneous; Accidents, Occupational; Disasters; Environmental Exposure; Environmental Monitoring; Female; Fetal Death; Hazardous Substances; Humans; Infant; Infant, Newborn; Isocyanates; Male; Mercury Poisoning; Pregnancy; Reproduction | 1993 |
The Bhopal accident and methyl isocyanate toxicity.
Topics: Accidents, Occupational; Animals; Cardiovascular System; Cell Cycle; Disasters; Eye; Guinea Pigs; Humans; Immunity; India; Isocyanates; Lung; Mice; Nervous System; Rabbits; Rats; Reproduction; Respiratory Tract Diseases; Skin | 1993 |
Persistent respiratory effects in survivors of the Bhopal disaster.
Topics: Adult; Air Pollutants; Antisickling Agents; Chemical Industry; Disasters; Follow-Up Studies; Humans; India; Isocyanates; Lung; Lung Diseases, Obstructive | 1998 |
Ocular effects of exposure to industrial chemicals: clinical management and proteomic approaches to damage assessment.
Topics: Accidents, Occupational; Acids; Alkalies; Ammonia; Burns, Chemical; Chemical Warfare Agents; Chlorine Compounds; Disasters; Eye; Eye Burns; Eye Proteins; Hazardous Substances; Humans; Isocyanates; Mechlorethamine; Mustard Gas; Proteins; Proteomics; Risk Assessment; Wound Healing | 2007 |
Laromustine, a sulfonyl hydrolyzing alkylating prodrug for cancer therapy.
Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Clinical Trials as Topic; Humans; Hydrazines; Isocyanates; Middle Aged; Neoplasms; Prodrugs; Sulfonamides | 2009 |
A pragmatic & translational approach of human biomonitoring to methyl isocyanate exposure in Bhopal.
Topics: Biomarkers; Environmental Exposure; Environmental Monitoring; Genomics; Humans; India; Isocyanates; Risk Assessment; Translational Research, Biomedical | 2012 |
Methyl isocyanate and carcinogenesis: bridgeable gaps in scientific knowledge.
Topics: Animals; Breast Neoplasms; Carcinoma, Acinar Cell; Cell Transformation, Neoplastic; Female; Genomic Instability; Humans; Isocyanates; Lung Neoplasms; Male; Neoplasms; Pheochromocytoma; Rats | 2012 |
A retrospective review of cytogenetic studies on methyl isocyanate with special reference to the Bhopal gas tragedy: is the next generation also at risk?
Topics: Animals; Bhopal Accidental Release; Cytogenetic Analysis; DNA Damage; Female; Humans; Isocyanates; Lymphocytes; Pregnancy; Prenatal Exposure Delayed Effects | 2013 |
Stress induced premature senescence: a new culprit in ovarian tumorigenesis?
Topics: Biomarkers; Carcinogenesis; Cell Transformation, Neoplastic; Cellular Senescence; Epithelial Cells; Female; Histones; Humans; Isocyanates; Ovarian Neoplasms; Ovary; Stress, Physiological; Telomere Shortening; Telomeric Repeat Binding Protein 2 | 2014 |
Molecular bio-dosimetry for carcinogenic risk assessment in survivors of Bhopal gas tragedy.
Topics: Antisickling Agents; Bhopal Accidental Release; Carcinogens; Disasters; Humans; Incidence; India; Isocyanates; Neoplasms; Radiometry; Risk Assessment; Survival Rate; Survivors | 2015 |
3 trial(s) available for cyanates and methyl isocyanate
| Article | Year |
|---|---|
A study of cognitive functions in methyl-iso-cyanate victims one year after bhopal accident.
Topics: Accidents, Occupational; Adolescent; Adult; Age Factors; Aged; Cognition Disorders; Education; Female; Humans; India; Isocyanates; Male; Middle Aged; Psychometrics | 1997 |
Cytogenetic changes in the Bhopal population exposed to methyl isocyanate (MIC) in 1984: Then and 30 years later.
Topics: Bhopal Accidental Release; Chromosome Aberrations; Female; Follow-Up Studies; Humans; India; Isocyanates; Male; Middle Aged | 2017 |
Effect of age at exposure on chromosome abnormalities in MIC-exposed Bhopal population detected 30 years post-disaster.
Topics: Adult; Age Factors; Chemical Hazard Release; Child; Child, Preschool; Chromosome Aberrations; Disasters; Environmental Exposure; Female; Follow-Up Studies; Humans; India; Infant; Isocyanates; Male | 2018 |
258 other study(ies) available for cyanates and methyl isocyanate
| Article | Year |
|---|---|
Methylisocyanate as an antisickling agent and its reaction with hemoglobin S.
Topics: Antisickling Agents; Binding Sites; Carbamates; Cyanates; Erythrocytes; Hemoglobin, Sickle; Humans; Isocyanates; Kinetics; Oxygen; Protein Binding | 1976 |
Mutagenicity of N,N'-dimethylurea and methylamine hydrochloride in the Ames Salmonella/microsome test: absence of mutagenic response.
Topics: Cyanates; Enzyme Activation; Isocyanates; Liver Extracts; Methylamines; Methylurea Compounds; Microbial Sensitivity Tests; Microsomes, Liver; Mutagenesis; Mutagenicity Tests; Salmonella typhimurium | 1992 |
Selective reactivities of isocyanates towards DNA bases and genotoxicity of methylcarbamoylation of DNA.
Topics: Carbamates; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Coliphages; Cyanates; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Dideoxynucleosides; DNA, Bacterial; DNA, Viral; Escherichia coli; Isocyanates; Methylation; Mutagenicity Tests; Mutagens; Transfection | 1992 |
Sequential respiratory, psychologic, and immunologic studies in relation to methyl isocyanate exposure over two years with model development.
Topics: Adult; Age Factors; Antisickling Agents; Cohort Studies; Cyanates; Environmental Exposure; Female; Follow-Up Studies; Humans; Immunoglobulin E; India; Isocyanates; Lung Diseases; Male; Middle Aged; Models, Biological; Neuromuscular Diseases; Psychophysiologic Disorders; Radiography; Sex Factors | 1992 |
In vitro and in vivo effect of methyl isocyanate on rat liver mitochondrial respiration.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Cell Hypoxia; Cyanates; Electron Transport; Injections, Subcutaneous; Isocyanates; Male; Methylamines; Methylurea Compounds; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Rats; Rats, Wistar | 1992 |
Monitoring of haemoglobin-methyl isocyanate adduct by high-performance liquid chromatography with diode array detector.
Topics: Accidents; Animals; Chromatography, High Pressure Liquid; Cyanates; Hemoglobins; Humans; India; Isocyanates; Rats | 1992 |
Inhalation toxicity of methylisocyanate: assessment of germ cell mutagenicity and reproductive effects in rats.
Topics: Administration, Inhalation; Animals; Cyanates; Female; Germ Cells; Isocyanates; Male; Mutagenicity Tests; Rats; Rats, Inbred Strains; Reproduction | 1992 |
Acute toxicity of methyl isocyanate in rabbit: in vitro and in vivo effects on rabbit erythrocyte membrane.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Antisickling Agents; Cyanates; Dose-Response Relationship, Drug; Erythrocyte Membrane; Female; Injections, Subcutaneous; Isocyanates; Osmotic Fragility; Potassium; Rabbits; Sodium | 1992 |
Does methyl isocyanate interaction with normal hemoglobin alter its structure and function?
Topics: Animals; Antisickling Agents; Cell Hypoxia; Circular Dichroism; Color; Cyanates; Electrophoresis, Cellulose Acetate; Hemoglobins; Isocyanates; Rabbits; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 1992 |
Trojan horse. Did a protective peptide exacerbate Bhopal injuries?
Topics: Accidents, Occupational; Burns, Chemical; Cyanates; Disasters; Gas Poisoning; Glutathione; Humans; India; Isocyanates | 1992 |
Toxicity of the methyl isocyanate metabolite S-(N-methylcarbamoyl)GSH on mouse embryos in culture.
Topics: Animals; Cell Membrane; Culture Techniques; Cyanates; DNA; Egg Proteins; Embryo, Mammalian; Glutathione; Isocyanates; Mice; Sulfhydryl Compounds; Thymidine; Yolk Sac | 1992 |
Long term pulmonary impairment following a single exposure to methyl isocyanate.
Topics: Administration, Inhalation; Animals; Antisickling Agents; Body Weight; Carbon Dioxide; Cyanates; Eosine Yellowish-(YS); Guinea Pigs; Hematoxylin; Histocytochemistry; Isocyanates; Kidney; Larynx; Liver; Lung; Male; Organ Size; Oxygen Consumption; Respiration; Spleen; Time Factors | 1991 |
Objective thoracic CT scan findings in a Bhopal gas disaster victim.
Topics: Accidents, Occupational; Antisickling Agents; Cyanates; Environmental Exposure; Humans; India; Isocyanates; Lung; Male; Middle Aged; Tomography, X-Ray Computed | 1991 |
Acute toxicity of methyl isocyanate in mammals. IV. Biochemical and hematological changes in rabbits.
Topics: Animals; Bilirubin; Blood Proteins; Cholesterol; Cyanates; Female; Hematocrit; Hemoglobins; Isocyanates; Lethal Dose 50; Leukocyte Count; Lung; Organ Size; Rabbits; Urea; Urobilinogen | 1991 |
GC-NPD and GC-MS analysis of preserved tissue of Bhopal gas disaster: evidence of methyl carbamylation in post-mortem blood.
Topics: Accidents, Occupational; Antisickling Agents; Chromatography, Gas; Cyanates; Disasters; Environmental Exposure; Humans; Hydantoins; India; Isocyanates; Mass Spectrometry; Postmortem Changes; Reproducibility of Results | 1991 |
GC-MS identification of MIC trimer: a constituent of tank residue in preserved autopsy blood of Bhopal gas victims.
Topics: Accidents, Occupational; Antisickling Agents; Autopsy; Cyanates; Disasters; Environmental Exposure; Humans; India; Isocyanates; Mass Spectrometry; Retrospective Studies | 1991 |
Modulation of microsomal membrane associated detoxication enzymes activity by methyl isocyanate (MIC) exposure.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cyanates; Glutathione Transferase; Inactivation, Metabolic; Isocyanates; Lung; Male; Membranes; Microsomes; Rats; Sulfhydryl Compounds | 1991 |
Cytogenetic studies on MIC gas-exposed persons in Bhopal.
Topics: Accidents, Occupational; Chromosome Aberrations; Chromosome Banding; Cyanates; Humans; India; Isocyanates; Sister Chromatid Exchange | 1991 |
Mass deaths by gas or chemical poisoning. A historical perspective.
Topics: Accidents, Occupational; Chemical Warfare; Cyanates; Disasters; Europe; Gas Poisoning; History, 19th Century; History, 20th Century; History, Ancient; Humans; India; Isocyanates | 1991 |
Chronic exposure to a simulated urban profile of ozone alters ventilatory responses to carbon dioxide challenge in rats.
Topics: Aging; Air Pollutants; Airway Resistance; Animals; Body Weight; Carbon Dioxide; Cyanates; Isocyanates; Lung; Lung Compliance; Male; Ozone; Rats; Rats, Inbred F344; Respiration | 1991 |
Inhalation toxicity of methyl isocyanate: biochemical and cytological profile of bronchoalveolar lavage fluid in rats.
Topics: Administration, Inhalation; Animals; Antisickling Agents; Body Weight; Bronchoalveolar Lavage Fluid; Cyanates; Isocyanates; Lactates; Lactic Acid; Lung; Male; N-Acetylneuraminic Acid; Proteins; Rats; Rats, Inbred Strains; Sialic Acids; Trachea | 1991 |
A study on the B cell activity in protein deficient rats exposed to methyl isocyanate vapour.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cyanates; Female; Isocyanates; Lymphocyte Activation; Protein Deficiency; Rats; Volatilization | 1991 |
Acute toxicity of methyl isocyanate in mammals. III. Electroencephalographic changes in rabbits.
Topics: Animals; Brain; Cyanates; Electroencephalography; Female; Isocyanates; Lethal Dose 50; Rabbits | 1990 |
Cytogenetic studies of chromosome aberrations.
Topics: Antisickling Agents; Chromosome Aberrations; Cyanates; Cytogenetics; Data Collection; Humans; Isocyanates; Male; Research Design; Testicular Neoplasms | 1990 |
Effect of methyl isocyanate (MIC) on rat erythrocytes.
Topics: Adenosine Triphosphatases; Animals; Antisickling Agents; Ca(2+) Mg(2+)-ATPase; Carbon Dioxide; Cation Transport Proteins; Cyanates; Erythrocyte Membrane; Erythrocytes; Isocyanates; Male; Microscopy, Electron, Scanning; Partial Pressure; Rats; Rats, Inbred Strains | 1990 |
Effects of methyl isocyanate on rat brain cells in culture.
Topics: Animals; Antisickling Agents; Brain; Cells, Cultured; Cyanates; Dose-Response Relationship, Drug; Isocyanates; Microscopy, Electron; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Search for chromosomal variations among gas-exposed persons in Bhopal.
Topics: Accidents, Occupational; Chromosome Aberrations; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Karyotyping; Lymphocytes; Male | 1990 |
S-(N-methylcarbamoyl)glutathione: a reactive S-linked metabolite of methyl isocyanate.
Topics: Animals; Bile; Biotransformation; Cyanates; Cysteine; Glutathione; Isocyanates; Kinetics; Male; Mass Spectrometry; Rats; Rats, Inbred Strains | 1990 |
Dissociation between maternal and fetal toxicity of methyl isocyanate in mice and rats.
Topics: Administration, Inhalation; Animals; Culture Techniques; Cyanates; Dexamethasone; Embryonic and Fetal Development; Female; Fetus; Gases; Hormones; Isocyanates; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Pregnancy; Progesterone; Rats; Rats, Inbred Strains | 1990 |
Bhopal: deal is less than final.
Topics: Accidents, Occupational; Cyanates; Gases; Humans; India; Isocyanates; Jurisprudence | 1990 |
Delayed eye and other consequences from exposure to methyl isocyanate: 93% follow up of exposed and unexposed cohorts in Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Cataract; Child; Child, Preschool; Cohort Studies; Cyanates; Environmental Exposure; Eye Diseases; Female; Follow-Up Studies; Humans; India; Infant; Isocyanates; Male; Middle Aged; Visual Acuity | 1990 |
Cytogenetic studies in human populations exposed to gas leak at Bhopal, India.
Topics: Accidents, Occupational; Cell Cycle; Chromosome Aberrations; Cyanates; DNA Replication; Environmental Health; Female; Humans; India; Isocyanates; Male; Sister Chromatid Exchange | 1990 |
Uptake and distribution of 14C during and following inhalation exposure to radioactive toluene diisocyanate.
Topics: Administration, Inhalation; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cyanates; Guinea Pigs; Isocyanates; Male; Metabolic Clearance Rate; Radiochemistry; Regression Analysis; Structure-Activity Relationship; Tissue Distribution; Toluene 2,4-Diisocyanate | 1989 |
Long-term effects of methyl isocyanate.
Topics: Accidents, Occupational; Acute Disease; Air Pollutants; Cyanates; Humans; India; Isocyanates; Pulmonary Edema; Time Factors | 1989 |
Long-term effects of methyl isocyanate.
Topics: Cyanates; Humans; Hydrogen Cyanide; India; Isocyanates | 1989 |
Bronchoalveolar lavage study in victims of toxic gas leak at Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Bronchoalveolar Lavage Fluid; Cyanates; Disasters; Environmental Exposure; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged; Pulmonary Fibrosis; Smoking | 1989 |
Genotoxicity studies on mice after short term inhalation exposure to methyl isocyanate.
Topics: Administration, Inhalation; Animals; Bone Marrow; Chromosome Aberrations; Cyanates; Dose-Response Relationship, Drug; Female; Isocyanates; Male; Mice; Micronucleus Tests; Mutagens | 1989 |
Isolation of methylcarbamoyl-adducts of adenine and cytosine following in vitro reaction of methyl isocyanate with calf thymus DNA.
Topics: Adenine; Animals; Antisickling Agents; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Paper; Cyanates; Cytosine; Deoxyribonucleotides; DNA; Isocyanates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet | 1989 |
Acute and subacute toxicity study of inhaled methyl isocyanate in Charles Foster rats.
Topics: Administration, Inhalation; Animals; Behavior, Animal; Cyanates; Hematocrit; Hemoglobins; Isocyanates; Kidney; Leukocyte Count; Liver; Lung; Platelet Count; Rats | 1989 |
The effects of E7 and E11 mutations on the kinetics of ligand binding to R state human hemoglobin.
Topics: Antisickling Agents; Carboxyhemoglobin; Cyanates; Hemoglobins; Humans; Isocyanates; Kinetics; Ligands; Macromolecular Substances; Mutation; Oxyhemoglobins; Protein Binding | 1989 |
Non-specific cardiovascular depressant effect of methyl isocyanate (MIC) in rats.
Topics: Airway Resistance; Animals; Blood Pressure; Cyanates; Depression, Chemical; Heart Rate; Isocyanates; Lung; Male; Methylamines; Rats; Rats, Inbred Strains; Vagotomy | 1989 |
Carcinogenicity and pulmonary pathology associated with a single 2-hour inhalation exposure of laboratory rodents to methyl isocyanate.
Topics: Animals; Cyanates; Female; Isocyanates; Lung; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1989 |
Effect of subacute exposure to methyl isocyanate on testicular histomorphology in mice.
Topics: Administration, Inhalation; Animals; Body Weight; Cyanates; Isocyanates; Male; Mice; Spermatozoa; Testis | 1989 |
Information on methyl isocyanate.
Topics: Accidents, Occupational; Cyanates; Humans; India; Isocyanates; United Kingdom | 1985 |
Bhopal disaster: eye follow-up and analytical chemistry.
Topics: Accidents, Occupational; Chemical Industry; Chemical Phenomena; Chemistry; Cyanates; Eye Diseases; Humans; India; Isocyanates | 1985 |
Lens opacities induced in rat lenses by methyl isocyanate.
Topics: Animals; Cataract; Cyanates; In Vitro Techniques; Isocyanates; Rats | 1985 |
Methyl isocyanate: thiosulphate does not protect.
Topics: Animals; Cyanates; Isocyanates; Male; Rats; Thiosulfates | 1985 |
Long term pathology of lung, eye, and other organs following acute exposure of rats to methyl isocyanate.
Topics: Air Pollutants; Animals; Cyanates; Eye; Isocyanates; Lung; Pilot Projects; Rats; Time Factors | 1986 |
Immunological studies on mice exposed subacutely to methyl isocyanate.
Topics: Animals; Antibody Formation; Cyanates; Cytotoxicity, Immunologic; Female; Immune System; Isocyanates; Killer Cells, Natural; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice | 1987 |
Cardiopulmonary effects in awake rats four and six months after exposure to methyl isocyanate.
Topics: Airway Obstruction; Airway Resistance; Animals; Cardiomegaly; Cardiovascular System; Cyanates; Electrocardiography; Hypertension, Pulmonary; Isocyanates; Lung; Lung Compliance; Male; Rats; Rats, Inbred F344; Respiration; Tidal Volume; Time Factors | 1987 |
Inhibition of rat brain cytochrome oxidase activity by pyrolysed products of methyl isocyanate.
Topics: Animals; Brain; Cyanates; Electron Transport Complex IV; Female; Injections, Intraperitoneal; Isocyanates; Rats | 1987 |
The Bhopal disaster.
Topics: Accidents, Occupational; Air Pollutants; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates; Pesticides | 1987 |
Results of in vitro and in vivo genetic toxicity tests on methyl isocyanate.
Topics: Animals; Bone Marrow; Chromosome Aberrations; Cricetinae; Cyanates; Drosophila melanogaster; In Vitro Techniques; Isocyanates; Leukemia L5178; Lung; Mice; Mutagenicity Tests; Mutagens; Salmonella; Sister Chromatid Exchange | 1987 |
Acute ocular lesions in Bhopal gas tragedy.
Topics: Accidents, Occupational; Acute Disease; Conjunctival Diseases; Corneal Diseases; Cyanates; Eye Diseases; Female; Gas Poisoning; Humans; India; Isocyanates; Male | 1986 |
Ophthalmic survey of Bhopal victims--100 days after the tragedy.
Topics: Accidents, Occupational; Adolescent; Adult; Aged; Child; Child, Preschool; Cyanates; Eye Diseases; Female; Gas Poisoning; Humans; India; Infant; Infant, Newborn; Isocyanates; Male; Middle Aged; Morbidity; Vision Disorders | 1986 |
Acute toxicity of methyl isocyanate, administered subcutaneously in rabbits: changes in physiological, clinico-chemical and histological parameters.
Topics: 2,3-Diphosphoglycerate; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cyanates; Diphosphoglyceric Acids; Electrocardiography; Female; Heart Rate; Injections, Subcutaneous; Isocyanates; Kidney; Lactates; Lactic Acid; Lethal Dose 50; Liver; Lung; Pyruvates; Pyruvic Acid; Rabbits; Respiration | 1988 |
Effect of exercise on dyspnoea in rats inhaling sublethal concentration of methyl isocyanate (MIC).
Topics: Animals; Cyanates; Dyspnea; Isocyanates; Male; Physical Exertion; Rats; Rats, Inbred Strains | 1988 |
The cytogenetic evaluation of in vivo genotoxic and cytotoxic activity using rodent somatic cells.
Topics: Animals; Benzene; Butadienes; Carcinogenicity Tests; Chloroprene; Chromosome Aberrations; Cyanates; Female; Hemiterpenes; Isocyanates; Male; Mice; Mutagenicity Tests; Mutagens; Pentanes | 1988 |
Mutagenicity of methyl isocyanate in the modified test conditions of Ames Salmonella/microsome liquid-preincubation procedure.
Topics: Animals; Cyanates; Isocyanates; Male; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1988 |
Mutagenic and toxic effects of methylisocyanate (MIC) in Salmonella typhimurium.
Topics: Animals; Cyanates; Isocyanates; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1987 |
Inhibition of methyl isocyanate toxicity in mice by starvation and dexamethasone but not by sodium thiosulfate, atropine, and ethanol.
Topics: Animals; Atmosphere Exposure Chambers; Atropine; Body Weight; Corticosterone; Cyanates; Dexamethasone; Ethanol; Injections, Intraperitoneal; Isocyanates; Male; Mice; Starvation; Thiosulfates | 1988 |
Uptake and distribution of 14C during and following exposure to [14C]methyl isocyanate.
Topics: Animals; Bile; Carbon Radioisotopes; Cyanates; Glutathione; Guinea Pigs; Isocyanates; Male; Respiratory System; Tissue Distribution | 1988 |
Effects of methyl isocyanate on rat muscle cells in culture.
Topics: Animals; Cell Nucleus; Cell Survival; Cells, Cultured; Cyanates; Fibroblasts; Isocyanates; Microscopy, Electron; Muscles; Rats | 1988 |
Cytogenetic activity of methyl isocyanate in vivo in the mouse micronucleus test.
Topics: Animals; Bone Marrow; Cell Nucleus; Chromosomes; Cyanates; Dose-Response Relationship, Drug; Erythrocytes; Female; Isocyanates; Male; Mice; Mutagenicity Tests; Mutagens | 1988 |
In vivo binding of [1-14C]methylisocyanate to various tissue proteins.
Topics: Animals; Blood Proteins; Brain; Carbon Radioisotopes; Cyanates; Female; Isocyanates; Liver; Protein Binding; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1988 |
Gas chromatographic studies of the carbamylation of haemoglobin by methyl isocyanate in rats and rabbits.
Topics: Animals; Antisickling Agents; Chromatography, Gas; Cyanates; Hemoglobins; Hemolysis; In Vitro Techniques; Isocyanates; Rabbits; Rats | 1988 |
Exposure and response to methyl isocyanate: results of a community based survey in Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Aged; Chemical Industry; Child; Child, Preschool; Cyanates; Disasters; Environmental Exposure; Eye Diseases; Humans; India; Infant; Infant, Newborn; Isocyanates; Middle Aged; Respiration Disorders | 1988 |
Bhopal gas disaster: clinical & experimental studies.
Topics: Accidents, Occupational; Chemical Industry; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Male | 1988 |
Effect of exposure to toxic gas on the population of Bhopal: Part I--Epidemiological, clinical, radiological & behavioral studies.
Topics: Accidents, Occupational; Adolescent; Adult; Chemical Industry; Child; Cyanates; Disasters; Epidemiologic Methods; Female; Gas Poisoning; Humans; India; Isocyanates; Male; Memory; Middle Aged; Psychomotor Performance; Respiration | 1988 |
Effect of exposure to toxic gas on the population of Bhopal: Part II--Respiratory impairment.
Topics: Accidents, Occupational; Adult; Chemical Industry; Cyanates; Disasters; Female; Gas Poisoning; Humans; Isocyanates; Lung Volume Measurements; Male; Respiration | 1988 |
Effect of exposure to toxic gas on the population of Bhopal: Part III--Assessment of toxic manifestations in humans--haematological and biochemical studies.
Topics: Accidents, Occupational; Adolescent; Adult; Chemical Industry; Child; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged | 1988 |
Effect of exposure to toxic gas on the population of Bhopal: Part IV--Immunological and chromosomal studies.
Topics: Accidents, Occupational; Antibody Formation; Chemical Industry; Chromosome Aberrations; Cyanates; Disasters; Gas Poisoning; Humans; Immunoglobulins; India; Isocyanates | 1988 |
Inhalation toxicity studies of methyl isocyanate (MIC) in rats: Part I--Pulmonary pathology and genotoxicity evaluation.
Topics: Administration, Inhalation; Animals; Cyanates; Isocyanates; Lung; Male; Mutagenicity Tests; Rats | 1988 |
Inhalation toxicity studies on methyl isocyanate (MIC) in rats: Part II--Biochemical studies on hemolysates, lactate dehydrogenase, isoenzymes and lipid peroxidation.
Topics: Administration, Inhalation; Animals; Cyanates; Hemolysis; Isocyanates; Isoenzymes; L-Lactate Dehydrogenase; Lipid Peroxides; Male; Rats | 1988 |
Inhalation toxicity studies of methyl isocyanate (MIC) in rats: Part III--Studies on biotransformation enzymes.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Biotransformation; Cyanates; Glutathione Transferase; Isocyanates; Liver; Lung; Rats | 1988 |
Inhalation toxicity studies of methyl isocyanate (MIC) in rats: Part IV--Immunologic response of rats one week after exposure: effect on body and organ weights, phagocytic and DTH response.
Topics: Administration, Inhalation; Animals; Body Weight; Cyanates; Gas Poisoning; Hypersensitivity, Delayed; Isocyanates; Organ Size; Phagocytosis; Rats | 1988 |
Inhalation toxicity studies of methyl isocyanate (MIC) in rats: Part V--Immunologic response of rats two weeks after exposure: phagocytic response, endotoxin susceptibility, local lung immunity, mitogenic and DTH response.
Topics: Administration, Inhalation; Animals; Cyanates; Endotoxins; Gas Poisoning; Hypersensitivity, Delayed; Isocyanates; Lung; Male; Phagocytosis; Rats | 1988 |
A clinical study of toxic gas poisoning in Bhopal, India.
Topics: Accidents, Occupational; Adolescent; Adult; Chemical Industry; Child; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged | 1988 |
Evaluating the potential for genotoxic carcinogenicity of methyl isocyanate.
Topics: Animals; Carcinogens; Cyanates; Humans; Isocyanates; Mutagenicity Tests; Predictive Value of Tests; Probability; Rodentia | 1987 |
Early observations on lung function studies in symptomatic "gas" exposed population of Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Lung Diseases; Lung Volume Measurements; Male; Middle Aged | 1987 |
Scientific studies on Bhopal gas victims. Part-A.
Topics: Accidents; Cyanates; Gas Poisoning; Humans; India; Isocyanates | 1987 |
Clinical profile of gas leak victims in acute phase after Bhopal episode.
Topics: Accidents, Occupational; Adolescent; Adult; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged; Radiography; Retrospective Studies | 1987 |
Sequential respiratory changes in those exposed to the gas leak at Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Cyanates; Disasters; Female; Follow-Up Studies; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged; Respiratory Tract Diseases | 1987 |
Radiological spectrum of lung changes in gas exposed victims.
Topics: Accidents, Occupational; Adolescent; Adult; Child; Child, Preschool; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Infant; Isocyanates; Lung Diseases; Male; Middle Aged; Radiography | 1987 |
Psychiatric morbidity in patients attending clinics in gas affected areas in Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Aged; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged; Random Allocation; Self-Assessment; Stress Disorders, Post-Traumatic | 1987 |
Mental health needs of Bhopal disaster victims & training of medical officers in mental health aspects.
Topics: Accidents, Occupational; Cyanates; Disasters; Gas Poisoning; Health Services Needs and Demand; Health Services Research; Humans; India; Isocyanates; Medical Staff; Mental Health Services; Stress Disorders, Post-Traumatic | 1987 |
Neurological manifestations among those exposed to toxic gas at Bhopal.
Topics: Accidents, Occupational; Adult; Child; Cyanates; Disasters; Female; Follow-Up Studies; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged; Nervous System Diseases | 1987 |
Immunological, mutagenic & genotoxic investigations in gas exposed population of Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Antibody Formation; Child; Chromosome Aberrations; Cyanates; Disasters; Female; Gas Poisoning; Humans; Immunity, Cellular; India; Isocyanates; Male; Middle Aged | 1987 |
Morphological study of placentae of expectant mothers exposed to gas leak at Bhopal.
Topics: Accidents, Occupational; Cyanates; Disasters; Female; Gas Poisoning; Humans; India; Isocyanates; Placenta; Placenta Diseases; Pregnancy; Pregnancy Complications | 1987 |
Preliminary report on the spermatogenic function of male subjects exposed to gas at Bhopal.
Topics: Accidents, Occupational; Adult; Cyanates; Disasters; Gas Poisoning; Humans; India; Isocyanates; Male; Middle Aged; Sperm Count; Sperm Motility; Spermatogenesis | 1987 |
Acute toxicity of methyl isocyanate and ineffectiveness of sodium thiosulphate in preventing its toxicity.
Topics: Animals; Antitoxins; Cyanates; Cyanides; Female; Isocyanates; Lethal Dose 50; Male; Mice; Rats; Rats, Inbred Strains; Thiosulfates | 1987 |
Effects of inhaled sublethal concentration of methyl isocyanate on lung mechanics in rats.
Topics: Administration, Inhalation; Animals; Cyanates; Isocyanates; Lung; Male; Rats; Rats, Inbred Strains; Respiration Disorders | 1987 |
Sequential study of thiocyanate levels in Bhopal water following methyl isocyanate gas leakage.
Topics: Accidents, Occupational; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates; Thiocyanates; Time Factors; Water Pollution, Chemical | 1986 |
Ophthalmic survey of Bhopal victims 104 days after the tragedy.
Topics: Accidents, Occupational; Adult; Chemical Industry; Child; Cyanates; Disasters; Eye Diseases; Female; Humans; India; Isocyanates; Male; Night Blindness | 1986 |
Chronic ocular lesions in Bhopal gas tragedy.
Topics: Accidents, Occupational; Cyanates; Disasters; Environmental Exposure; Eye Diseases; Female; Humans; India; Isocyanates; Male | 1987 |
Immunotoxicity studies in mice exposed to methyl isocyanate.
Topics: Animals; Antibody Formation; Atmosphere Exposure Chambers; Cyanates; Female; Hemolytic Plaque Technique; Isocyanates; Killer Cells, Natural; Lung; Mice | 1986 |
Genotoxicity studies of methyl isocyanate in Salmonella, Drosophila, and cultured Chinese hamster ovary cells.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Cyanates; Drosophila; Female; Isocyanates; Male; Mutagens; Salmonella; Sister Chromatid Exchange | 1987 |
Pathologic changes following acute methyl isocyanate inhalation and recovery in B6C3F1 mice.
Topics: Administration, Inhalation; Animals; Cyanates; Dose-Response Relationship, Drug; Female; Isocyanates; Lung; Male; Mice; Mice, Inbred Strains; Nasal Mucosa; Pulmonary Fibrosis; Thymus Gland | 1987 |
Histomorphologic changes induced by methyl isocyanate in lungs of rats and rabbits.
Topics: Animals; Antisickling Agents; Bronchitis; Cyanates; Hemorrhage; Isocyanates; Lung; Male; Pulmonary Emphysema; Rabbits; Rats; Species Specificity | 1987 |
Medical survey of methyl isocyanate gas affected population of Bhopal. Part I. General medical observations 15 weeks following exposure.
Topics: Accidents, Occupational; Adult; Chemical Industry; Child; Cyanates; Disasters; Eye Diseases; Female; Gastrointestinal Diseases; Humans; India; Isocyanates; Male; Nervous System Diseases; Respiratory Tract Diseases; Time Factors | 1986 |
Medical survey of methyl isocyanate gas affected population of Bhopal. Part II. Pulmonary effects in Bhopal victims as seen 15 weeks after M.I.C. exposure.
Topics: Accidents, Occupational; Adult; Chemical Industry; Child; Cyanates; Disasters; Humans; India; Isocyanates; Respiratory Tract Diseases; Time Factors | 1986 |
A survey of Bhopal children affected by methyl isocyanate gas.
Topics: Accidents, Occupational; Chemical Industry; Child; Cyanates; Disasters; Eye Diseases; Female; Gastrointestinal Diseases; Humans; India; Isocyanates; Male; Nervous System Diseases; Respiratory Tract Diseases | 1986 |
Gynaecological and obstetrical survey of Bhopal women following exposure to methyl isocyanate.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Accidents, Occupational; Chemical Industry; Cyanates; Disasters; Female; Genital Diseases, Female; Humans; India; Infant, Newborn; Isocyanates; Pregnancy; Risk | 1986 |
Reproductive toxicity of methyl isocyanate in mice.
Topics: Adrenal Cortex Hormones; Animals; Body Weight; Cyanates; Dose-Response Relationship, Drug; Female; Fetal Death; Gases; Gestational Age; Isocyanates; Male; Mice; Pregnancy; Pregnancy, Animal; Progesterone; Reproduction | 1987 |
Penetration of methyl isocyanate through organic vapor and acid gas respirator cartridges.
Topics: Cyanates; Isocyanates; Kinetics; Permeability; Protective Devices; Quality Control; Respiratory Protective Devices | 1987 |
Methyl isocyanate liquid and vapor permeation through selected respirator diaphragms and chemical protective clothing.
Topics: Cyanates; Isocyanates; Permeability; Protective Clothing; Protective Devices; Quality Control; Respiratory Protective Devices | 1987 |
Application of tryptamine as a derivatizing agent for airborne isocyanates determination. Part 1. Model of derivatisation of methyl isocyanate characterised by fluorescence and amperometric detection in high-performance liquid chromatography.
Topics: Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Cyanates; Electrochemistry; Isocyanates; Spectrometry, Fluorescence; Tryptamines | 1987 |
The toxicity of methyl isocyanate. March 12-13, 1986, Research Triangle Park, NC. Proceedings.
Topics: Animals; Cyanates; Humans; Isocyanates | 1987 |
Effect of methyl isocyanate (MIC) gas on the eyes of Fischer 344 rats.
Topics: Animals; Cornea; Cyanates; Eye; Female; Isocyanates; Male; Rats; Rats, Inbred F344; Tears | 1987 |
Respiratory tract changes in guinea pigs, rats, and mice following a single six-hour exposure to methyl isocyanate vapor.
Topics: Animals; Body Weight; Cyanates; Epithelium; Female; Guinea Pigs; Isocyanates; Lethal Dose 50; Male; Mice; Rats; Rats, Inbred F344; Respiratory System; Species Specificity; Time Factors | 1987 |
Methyl isocyanate eight-day vapor inhalation study with Fischer 344 rats.
Topics: Animals; Behavior, Animal; Blood; Body Weight; Cyanates; Eating; Eye; Female; Isocyanates; Male; Organ Size; Rats; Rats, Inbred F344; Respiratory System; Time Factors | 1987 |
Eighty-five day postexposure follow-up study in Fischer 344 rats after repeated exposures to methyl isocyanate vapor.
Topics: Acrolein; Animals; Body Weight; Cyanates; Female; Isocyanates; Male; Rats; Rats, Inbred F344; Respiratory System; Time Factors | 1987 |
Biological effects of short-term, high-concentration exposure to methyl isocyanate. I. Study objectives and inhalation exposure design.
Topics: Animals; Cholinesterase Inhibitors; Cyanates; Female; Guinea Pigs; Humans; Isocyanates; Lethal Dose 50; Lung; Male; Rats; Rats, Inbred Strains; Time Factors; Volatilization | 1987 |
The toxicity of inhaled methyl isocyanate in F344/N rats and B6C3F1 mice. II. Repeated exposure and recovery studies.
Topics: Animals; Blood; Body Weight; Cyanates; Female; Isocyanates; Male; Mice; Organ Size; Rats; Rats, Inbred F344; Respiratory System; Time Factors | 1987 |
Myelotoxicity induced in female B6C3F1 mice by inhalation of methyl isocyanate.
Topics: Animals; Bone Marrow; Colony-Forming Units Assay; Cyanates; Erythrocytes; Female; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Isocyanates; Macrophages; Mice; Time Factors | 1987 |
Methyl isocyanate: reproductive and developmental toxicology studies in Swiss mice.
Topics: Animals; Cyanates; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Isocyanates; Male; Maternal-Fetal Exchange; Mice; Pregnancy; Reproduction; Time Factors | 1987 |
Epidemiological and experimental studies on the effects of methyl isocyanate on the course of pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Cyanates; Epidemiologic Methods; Female; Fetal Death; Humans; India; Infant Mortality; Isocyanates; Maternal-Fetal Exchange; Mice; Pregnancy; Pregnancy Complications | 1987 |
Sensory and pulmonary irritation of methyl isocyanate in mice and pulmonary irritation and possible cyanidelike effects of methyl isocyanate in guinea pigs.
Topics: Airway Obstruction; Animals; Cough; Cyanates; Cyanides; Guinea Pigs; Isocyanates; Lung; Male; Maximum Allowable Concentration; Mice; Nasal Mucosa; Oxygen Consumption; Respiration; Sensory Receptor Cells; Time Factors | 1987 |
The antibody response to methyl isocyanate: experimental and clinical findings.
Topics: Animals; Antibody Formation; Antibody Specificity; Cyanates; Guinea Pigs; Humans; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; Isocyanates; Male; Radioallergosorbent Test | 1987 |
Evaluation of sister chromatid exchange and cytotoxicity in murine tissues in vivo and lymphocytes in vitro following methyl isocyanate exposure.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cyanates; In Vitro Techniques; Isocyanates; Kinetics; Lymphocytes; Macrophages; Male; Mice; Sister Chromatid Exchange | 1987 |
Biological effects of short-term, high-concentration exposure to methyl isocyanate. VI. In vitro and in vivo complement activation studies.
Topics: Animals; Complement Activation; Complement C3; Complement C5; Complement System Proteins; Cyanates; Female; Guinea Pigs; Humans; In Vitro Techniques; Isocyanates | 1987 |
Biological effects of short-term, high-concentration exposure to methyl isocyanate. II. Blood chemistry and hematologic evaluations.
Topics: Animals; Blood; Cholinesterase Inhibitors; Creatine Kinase; Cyanates; Erythrocytes; Female; Guinea Pigs; Humans; In Vitro Techniques; Isocyanates; Leukocyte Count; Lung; Male; Neutrophils; Rats; Rats, Inbred Strains | 1987 |
Biological effects of short-term, high-concentration exposure to methyl isocyanate. III. Influence on gas exchange in the guinea pig lung.
Topics: Animals; Cyanates; Female; Guinea Pigs; Hydrogen-Ion Concentration; Hypoxia; Isocyanates; Pressure; Pulmonary Circulation; Pulmonary Gas Exchange; Trachea | 1987 |
Biological effects of short-term, high-concentration exposure to methyl isocyanate. IV. Influence on the oxygen-binding properties of guinea pig blood.
Topics: Acidosis; Animals; Blood; Cyanates; Female; Guinea Pigs; Isocyanates; Oxygen | 1987 |
Biological effects of short-term, high-concentration exposure to methyl isocyanate. V. Morphologic evaluation of rat and guinea pig lungs.
Topics: Airway Obstruction; Animals; Bronchi; Cyanates; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; Hypoxia; Isocyanates; Lung; Necrosis; Rats; Rats, Inbred Strains | 1987 |
Inhalation exposure system used for acute and repeated-dose methyl isocyanate exposures of laboratory animals.
Topics: Animals; Computer Systems; Cyanates; Environment, Controlled; Environmental Monitoring; Isocyanates; Mice; Rats; Volatilization | 1987 |
Biochemistry of protein-isocyanate interactions: a comparison of the effects of aryl vs. alkyl isocyanates.
Topics: Affinity Labels; Cholinesterase Inhibitors; Cyanates; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Isocyanates; Proteins; Structure-Activity Relationship | 1987 |
Toxicity of inhaled methyl isocyanate in F344/N rats and B6C3F1 mice. I. Acute exposure and recovery studies.
Topics: Animals; Antidotes; Blood; Body Weight; Cyanates; Cyanides; Female; Isocyanates; Lung; Male; Mice; Organ Size; Rats; Rats, Inbred F344; Respiratory System; Time Factors | 1987 |
Two-hour methyl isocyanate inhalation and 90-day recovery study in B6C3F1 mice.
Topics: Animals; Cyanates; Epithelium; Female; Isocyanates; Lung Diseases; Male; Mice; Necrosis; Respiratory System; Sex Factors; Thymus Gland; Time Factors | 1987 |
Two-hour methyl isocyanate inhalation exposure and 91-day recovery: a preliminary description of pathologic changes in F344 rats.
Topics: Animals; Cyanates; Digestive System; Female; Isocyanates; Lung; Male; Rats; Rats, Inbred F344; Respiratory System; Thymus Gland; Time Factors | 1987 |
Ultrastructural changes in the nasal mucosa of Fischer 344 rats and B6C3F1 mice following an acute exposure to methyl isocyanate.
Topics: Animals; Cyanates; Epithelium; Isocyanates; Male; Mice; Microscopy, Electron; Nasal Mucosa; Necrosis; Olfactory Mucosa; Rats; Rats, Inbred F344; Regeneration; Time Factors | 1987 |
Functional evidence of persistent airway obstruction in rats following a two-hour inhalation exposure to methyl isocyanate.
Topics: Airway Obstruction; Animals; Cyanates; Isocyanates; Male; Pulmonary Gas Exchange; Rats; Rats, Inbred F344; Time Factors; Total Lung Capacity | 1987 |
Sensory irritation of methylisocyanate vapor.
Topics: Animals; Antisickling Agents; Cyanates; Irritants; Isocyanates; Male; Mice; Mice, Inbred ICR; Respiration | 1987 |
Release of methyl isocyanate from the antitumor agent caracemide (NSC-253272).
Topics: Antineoplastic Agents; Brain; Cyanates; Hydroxyurea; Isocyanates | 1987 |
Medico-legal aspects of the Bhopal tragedy.
Topics: Accidents, Occupational; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates; Jurisprudence; United States | 1986 |
Four-day repeated inhalation and recovery study of methyl isocyanate in F344 rats and B6C3F1 mice.
Topics: Administration, Inhalation; Animals; Body Weight; Cyanates; Female; Isocyanates; Lung; Male; Mice; Nasal Cavity; Rats; Rats, Inbred F344; Respiratory System; Trachea | 1987 |
A mortality evaluation of employees with potential exposure to methyl isocyanate.
Topics: Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; West Virginia | 1986 |
Acute inhalation studies with methyl isocyanate vapor. I. Methodology and LC50 determinations in guinea pigs, rats, and mice.
Topics: Animals; Body Weight; Cyanates; Female; Guinea Pigs; Isocyanates; Lethal Dose 50; Lung; Male; Mice; Rats; Rats, Inbred F344; Species Specificity; Volatilization | 1986 |
Acute inhalation studies with methyl isocyanate vapor. II. Respiratory tract changes in guinea pigs, rats, and mice.
Topics: Animals; Cyanates; Epithelium; Female; Guinea Pigs; Isocyanates; Lung; Male; Mice; Nasal Cavity; Rats; Rats, Inbred F344; Respiratory System; Species Specificity; Trachea; Volatilization | 1986 |
Bright red blood of Bhopal victims: cyanide or MIC?
Topics: Accidents, Occupational; Blood; Chemical Industry; Color; Cyanates; Cyanides; Disasters; Hemoglobins; Humans; India; Isocyanates | 1986 |
Investigation by the Ames test of urine samples from rats exposed to methyl isocyanate.
Topics: Animals; Cyanates; Isocyanates; Mutagenicity Tests; Mutation; Rats; Rats, Inbred Strains; Urine | 1986 |
Mutagenicity of methylisocyanate and its reaction products to cultured mammalian cells.
Topics: Animals; Biotransformation; Cells, Cultured; Cyanates; Isocyanates; Leukemia L5178; Methylurea Compounds; Mice; Microsomes, Liver; Mutagenicity Tests; Rats; Urethane | 1986 |
Cytogenetic effects of methyl isocyanate exposure in Bhopal.
Topics: Accidents, Occupational; Chemical Industry; Chromosome Aberrations; Cyanates; Disasters; Humans; India; Isocyanates; Karyotyping; Lymphocytes; Sister Chromatid Exchange | 1986 |
The Bhopal tragedy--what has Swedish disaster medicine planning learned from it?
Topics: Accidents, Occupational; Chemical Industry; Cyanates; Disaster Planning; Disasters; Eye Injuries; Humans; India; Isocyanates; Relief Work; Respiratory Distress Syndrome | 1986 |
Sister chromatid exchange analysis in lung and peripheral blood lymphocytes of mice exposed to methyl isocyanate by inhalation.
Topics: Administration, Inhalation; Animals; Cell Cycle; Cells, Cultured; Cyanates; Female; Isocyanates; Lung; Lymphocytes; Male; Mice; Mice, Inbred Strains; Sex Factors; Sister Chromatid Exchange | 1987 |
Methyl isocyanate: an evaluation of in vivo cytogenetic activity.
Topics: Animals; Cell Division; Cell Nucleus; Chromosome Aberrations; Cyanates; DNA Replication; Erythrocytes; Female; Isocyanates; Male; Mice; Sex Factors; Sister Chromatid Exchange | 1987 |
Industrial disasters.
Topics: Accidents; Chemical Industry; Cyanates; Humans; India; Isocyanates | 1985 |
Chronobiologic considerations of the Bhopal methyl isocyanate disaster.
Topics: Accidents, Occupational; Circadian Rhythm; Cyanates; Humans; India; Isocyanates; Occupational Medicine | 1985 |
An eyewitness in Bhopal.
Topics: Cyanates; Disasters; Health Facilities; India; Isocyanates | 1985 |
Sensory and pulmonary irritation with exposure to methyl isocyanate.
Topics: Animals; Atmosphere Exposure Chambers; Cyanates; Dose-Response Relationship, Drug; Gases; Intubation, Intratracheal; Irritants; Isocyanates; Male; Mice; Respiration; Respiratory System; Time Factors | 1986 |
Stepped up inspections, laws mark Bhopal's legacy in the U.S.
Topics: Accidents, Occupational; Air Pollution; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates; Safety; United States | 1986 |
Tragedy can continue in human effects of chemical disaster.
Topics: Adolescent; Adult; Aged; Chemical Industry; Child; Child, Preschool; Cyanates; Disasters; Humans; India; Isocyanates; Middle Aged; Stress Disorders, Post-Traumatic | 1986 |
Bhopal and after.
Topics: Accidents, Occupational; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates | 1986 |
[Methylisocyanate].
Topics: Animals; Antibody Formation; Bronchial Spasm; Bronchopneumonia; Conjunctivitis; Cyanates; Dimethylnitrosamine; Humans; Isocyanates; Lethal Dose 50; Methylamines; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Rabbits; Rats | 1985 |
Bhopal tragedy's repercussions may reach American physicians.
Topics: Accidents, Occupational; Air Pollutants; Chemical Industry; Cyanates; Disasters; Humans; India; Isocyanates; United States | 1985 |
After coping with crisis, medicine ponders sequelae.
Topics: Accidents, Occupational; Air Pollutants; Cyanates; Disasters; Emergency Medical Services; Humans; India; Isocyanates; Lung Diseases | 1985 |
Does acute toxicity testing tell us anything useful? Methyl isocyanate as a test case.
Topics: Accidents, Occupational; Animals; Chemical Industry; Cyanates; Humans; Isocyanates; Lethal Dose 50; Toxicology; United Kingdom | 1985 |
American personal-injury lawyers at Bhopal. Ethics and public policy in mass disaster.
Topics: Air Pollutants, Occupational; Chemical Industry; Cyanates; Disasters; Ethics, Professional; Humans; India; Isocyanates; Jurisprudence; Public Policy; United States | 1985 |
[Notes on the disaster in Bhopal].
Topics: Aerosols; Biological Transport; Cyanates; Dexamethasone Isonicotinate; Disaster Planning; Disasters; Germany, West; Humans; Hypoxia; India; Isocyanates; Oxygen | 1985 |
The Bhopal tragedy.
Topics: Cyanates; Humans; India; Isocyanates; Safety | 1985 |
Ocular lesions following methyl isocyanate contamination: the Bhopal experience.
Topics: Air Pollutants; Burns, Chemical; Child; Cyanates; Disasters; Equipment Failure; Eye Burns; Humans; India; Isocyanates | 1985 |
Acute toxicity of methyl isocyanate: a preliminary study of the dose response for eye and other effects.
Topics: Animals; Behavior, Animal; Cornea; Cyanates; Dose-Response Relationship, Drug; Eye; Isocyanates; Male; Rats; Rats, Inbred Strains; Respiration; Thiocyanates | 1985 |
Effects of methyl isocyanate on the respiratory tract of rats.
Topics: Animals; Cyanates; Dose-Response Relationship, Drug; Epithelium; Isocyanates; Male; Microscopy, Electron; Pulmonary Edema; Rats; Respiration; Respiratory System | 1985 |
A detector tube for the analysis of methyl isocyanate in air or nitrogen purge gas;.
Topics: Air Pollution; Aniline Compounds; Azo Compounds; Chemical Phenomena; Chemistry; Color; Cyanates; Gels; Hot Temperature; Indicators and Reagents; Isocyanates; Nitrogen; Occupational Medicine; Silicon Dioxide | 1974 |
Calamity at Bhopal.
Topics: Accidents, Occupational; Cyanates; Herbicides; Humans; India; Isocyanates | 1984 |
Bhopal eye.
Topics: Accidents, Occupational; Cyanates; Disasters; Eye Diseases; Humans; India; Isocyanates | 1984 |
Autoradiographic analyses of guinea pig airway tissues following inhalation exposure to 14C-labeled methyl isocyanate.
Topics: Administration, Inhalation; Animals; Autoradiography; Cyanates; Eosine Yellowish-(YS); Epithelium; Guinea Pigs; Hematoxylin; Isocyanates; Lung; Nasal Cavity; Respiratory System; Respiratory Tract Diseases; Trachea | 1993 |
Chronic lung inflammation in victims of toxic gas leak at Bhopal.
Topics: Accidents, Occupational; Adult; Bronchoalveolar Lavage Fluid; Chronic Disease; Disasters; Environmental Exposure; Female; Fibronectins; Hazardous Substances; Humans; India; Isocyanates; Macrophages; Male; Middle Aged; Neutrophils; Pulmonary Fibrosis | 1995 |
Comparative toxicity of methyl isocyanate and its hydrolytic derivatives in rats. I. Pulmonary histopathology in the acute phase.
Topics: Administration, Inhalation; Animals; Antisickling Agents; Bronchitis; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrolysis; Hyperemia; Injections, Subcutaneous; Isocyanates; Lung; Lung Diseases, Interstitial; Male; Methylamines; Methylurea Compounds; Microscopy, Fluorescence; Necrosis; Pulmonary Edema; Rats; Rats, Wistar | 1994 |
Comparative toxicity of methyl isocyanate and its hydrolytic derivatives in rats. II. Pulmonary histopathology in the subacute and chronic phases.
Topics: Administration, Inhalation; Animals; Antisickling Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrolysis; Injections, Subcutaneous; Isocyanates; Lung; Lung Diseases, Interstitial; Lung Injury; Male; Methylamines; Methylurea Compounds; Pulmonary Edema; Pulmonary Fibrosis; Rats; Rats, Wistar; Time Factors | 1994 |
Persistently toxic. The Union Carbide accident in Bhopal continues to harm.
Topics: Accidents, Occupational; Antisickling Agents; Disasters; Female; Humans; India; Isocyanates; Male; Pregnancy | 1995 |
Histobiochemical changes in lung of protein deficient rats following repeated exposures of MIC vapour.
Topics: Acid Phosphatase; Administration, Inhalation; Aerosols; Alkaline Phosphatase; Animals; Antisickling Agents; Disease Models, Animal; Glutathione; Isocyanates; Lung; Male; Occupational Exposure; Protein Deficiency; Random Allocation; Rats | 1994 |
The ultimate poison center call--Bhopal.
Topics: Accidents, Occupational; Antisickling Agents; Disaster Planning; Humans; India; Isocyanates; Poison Control Centers | 1995 |
Acute histopathological changes induced by methyl isocyanate in lungs, liver, kidneys & spleen of rats.
Topics: Animals; Isocyanates; Kidney; Liver; Lung; Male; Rats; Rats, Wistar; Spleen | 1994 |
Inhibition of mouse embryonic, yolk sac, and limb-bud functions by the methyl isocyanate metabolite S-(N-methylcarbamoyl)glutathione.
Topics: Aminooxyacetic Acid; Animals; Antimetabolites; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Embryonic and Fetal Development; Endocytosis; Extremities; Female; Glutathione; Isocyanates; Isoxazoles; Leucine; Male; Mice; Pinocytosis; Pregnancy; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Yolk Sac | 1994 |
Isolation of an unknown compound, from both blood of Bhopal aerosol disaster victims and residue of tank E-610 of Union Carbide India Limited--chemical characterization of the structure.
Topics: Accidents, Occupational; Chemical Industry; Disasters; Humans; India; Isocyanates; Spiro Compounds | 1994 |
In vitro and in vivo effects of methyl isocyanate on rat brain mitochondrial respiration.
Topics: Animals; Antisickling Agents; Brain; Injections, Subcutaneous; Isocyanates; Male; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Wistar | 1994 |
Do the hydrolysis products, methylamine and N,N'-dimethylurea, play any role in the methyl isocyanate-induced haematological and biochemical changes in rabbits?
Topics: Animals; Antisickling Agents; Cyanates; Erythrocyte Count; Female; Hemoglobins; Hemorrhage; Hydrolysis; Isocyanates; Lactates; Lactic Acid; Lethal Dose 50; Leukocyte Count; Methylamines; Methylurea Compounds; Pyruvates; Pyruvic Acid; Rabbits; Serum Albumin; Urea | 1993 |
Modulation of biochemical and cytological profile of bronchoalveolar lavage constituents in rats following split-dose multiple inhalation exposure to methyl isocyanate.
Topics: Administration, Inhalation; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Cyanates; Dose-Response Relationship, Drug; Drug Administration Schedule; Irritants; Isocyanates; Lactates; Lactic Acid; Lung; Male; Proteins; Rats; Rats, Wistar; Sialic Acids | 1993 |
Selective and irreversible inhibition of glutathione reductase in vitro by carbamate thioester conjugates of methyl isocyanate.
Topics: Amino Acid Sequence; Binding Sites; Carbamates; Cysteine; Glutathione; Glutathione Reductase; Humans; Isocyanates; Molecular Sequence Data; NADP; Saccharomyces cerevisiae | 1994 |
Methyl isocyanate induced morphological changes in the seminiferous epithelium of rats maintained on normal or protein deficient diets.
Topics: Animals; Antisickling Agents; Body Weight; Isocyanates; Male; Protein Deficiency; Rats; Seminiferous Epithelium; Spermatogenesis; Testis | 1994 |
Bile duct hyperplasia and transient liver parenchymal cell alteration by methylisocyanate.
Topics: Animals; Bile Ducts; Blood Glucose; Cyanates; Hyperplasia; Isocyanates; Liver; Male; Mice | 1993 |
Role of lipid peroxidation in impairment of mitochondrial function at complex I by methyl isocyanate treatment of rats in vivo.
Topics: Animals; Cell Hypoxia; Iron; Isocyanates; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria, Liver; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Wistar | 1993 |
Methylisocyanate and actin polymerization: the in vitro effects of carbamylation.
Topics: Actins; Animals; Biuret; Buffers; Cyanates; Isocyanates; Lysine; Microscopy, Electron; Muscles; Polymers; Rabbits; Spectrometry, Fluorescence; Viscosity | 1993 |
Effect of methyl isocyanate on rabbit cardiac Na+, K(+)-ATPase.
Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphate; Aniline Compounds; Animals; Antisickling Agents; Ca(2+) Mg(2+)-ATPase; Circular Dichroism; Female; Isocyanates; Microsomes; Myocardium; Organophosphorus Compounds; Rabbits; Sodium-Potassium-Exchanging ATPase | 1995 |
Effects of prolonged low exposure to methyl isocyanate.
Topics: Air Pollutants, Occupational; Airway Obstruction; Analysis of Variance; Chemical Industry; Forced Expiratory Volume; Humans; Isocyanates; Longitudinal Studies; Lung; Occupational Exposure; Smoking; Time Factors; Vital Capacity | 1996 |
Late consequences of accidental exposure to inhaled irritants: RADS and the Bhopal disaster.
Topics: Accidents, Occupational; Asthma; Bronchial Hyperreactivity; Chemical Industry; Disasters; Environmental Exposure; Follow-Up Studies; Humans; India; Irritants; Isocyanates; Lung Diseases, Obstructive; Time Factors | 1996 |
Relationship between lung inflammation, changes in lung function and severity of exposure in victims of the Bhopal tragedy.
Topics: Accidents, Occupational; Adolescent; Adult; Bronchoalveolar Lavage; Cell Count; Chemical Industry; Disasters; Environmental Exposure; Female; Follow-Up Studies; Forced Expiratory Volume; Gas Poisoning; Humans; India; Isocyanates; Leukocyte Count; Lung; Lymphocyte Count; Lymphocytes; Macrophages; Male; Middle Aged; Neutrophils; Pneumonia; Radiography; Retrospective Studies; Smoking; Vital Capacity | 1996 |
Respiratory morbidity 10 years after the Union Carbide gas leak at Bhopal: a cross sectional survey. The International Medical Commission on Bhopal.
Topics: Accidents, Occupational; Adolescent; Adult; Air Pollutants; Chemical Industry; Cough; Cross-Sectional Studies; Disasters; Dyspnea; Environmental Exposure; Female; Forced Expiratory Volume; Humans; India; Isocyanates; Lung Diseases, Obstructive; Male; Middle Aged; Respiratory Sounds; Vital Capacity | 1997 |
Commentary: industry can damage your health.
Topics: Accidents, Occupational; Adolescent; Adult; Air Pollutants; Chemical Industry; Disasters; Environmental Exposure; Female; Humans; India; Isocyanates; Lung Diseases, Obstructive; Male; Middle Aged; Risk Assessment | 1997 |
Commentary: assessing the effects of environmental pollution when people know that they have been exposed.
Topics: Accidents, Occupational; Adolescent; Adult; Air Pollutants; Chemical Industry; Cross-Sectional Studies; Disasters; Environmental Exposure; Female; Humans; India; Isocyanates; Lung Diseases, Obstructive; Male; Middle Aged; Risk Assessment | 1997 |
The lessons of Bhopal [toxic] MIC gas disaster scope for expanding global biomonitoring and environmental specimen banking.
Topics: Accidents, Occupational; Biological Specimen Banks; Disasters; Environmental Monitoring; Forensic Medicine; Humans; India; International Cooperation; Isocyanates; Toxicology | 1997 |
Methyl isocyanate exposure.
Topics: Accidents, Occupational; Disasters; Humans; India; Isocyanates; Lung Diseases, Obstructive; Occupational Diseases; Survival Rate | 1998 |
Coming soon: the pocket DNA sequencer.
Topics: Chemistry; Chemistry, Pharmaceutical; Costs and Cost Analysis; Drug Evaluation, Preclinical; Isocyanates; Miniaturization; Sequence Analysis, DNA | 1998 |
Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas.
Topics: Antineoplastic Agents, Alkylating; Bacteriophage T7; Carmustine; Cross-Linking Reagents; DNA; DNA Damage; DNA, Viral; Isocyanates; Lomustine; Semustine | 2000 |
Cancer patterns of lung, oropharynx and oral cavity cancer in relation to gas exposure at Bhopal.
Topics: Adult; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Environmental Exposure; Female; Humans; Incidence; India; Isocyanates; Lung Neoplasms; Male; Middle Aged; Mouth Neoplasms; Oropharyngeal Neoplasms; Registries; Risk Factors | 1999 |
Determination of airborne methyl isocyanate as dibutylamine or 1-(2-methoxyphenyl)piperazine derivatives by liquid and gas chromatography.
Topics: Air Pollutants, Occupational; Antisickling Agents; Chemical Industry; Chromatography, Gas; Chromatography, Liquid; Isocyanates | 2000 |
N-methylcarbamoylated valine of hemoglobin in humans after exposure to N,N-dimethylformamide: evidence for the formation of methyl isocyanate?
Topics: Antisickling Agents; Carbamates; Dimethylformamide; Hemoglobins; Humans; Hydantoins; Isocyanates; Magnetic Resonance Spectroscopy; Models, Molecular; Occupational Exposure; Organophosphorus Compounds; Valine | 2001 |
Two rotors potential scans and vibrational assignments for dihalomethylsulfonyl isocyanates.
Topics: Isocyanates; Models, Chemical; Oxygen; Quantum Theory; Spectrophotometry, Infrared; Sulfones; Sulfur; Temperature | 2002 |
Personal exposure and long-term health effects in survivors of the union carbide disaster at bhopal.
Topics: Adult; Antisickling Agents; Cross-Sectional Studies; Environmental Exposure; Female; Follow-Up Studies; Forecasting; Geography; Health Status; Humans; India; Isocyanates; Lung Diseases; Male; Respiratory Function Tests; Risk Assessment | 2002 |
Bhopal's health disaster continues to unfold.
Topics: Cause of Death; Chemical Industry; Developing Countries; Disasters; Explosions; Humans; India; Isocyanates; Liability, Legal; Pesticides; Poisoning | 2002 |
Development of a diffusive sampling method for determination of methyl isocyanate in air.
Topics: Air Pollution, Indoor; Antisickling Agents; Diffusion; Environmental Monitoring; Humans; Isocyanates; Occupational Exposure; Reference Values; Specimen Handling | 2002 |
Diffusive sampling of methyl isocyanate using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ) as derivatizing agent.
Topics: Absorption; Antisickling Agents; Chromatography, High Pressure Liquid; Diffusion; Environmental Monitoring; Humidity; Isocyanates; Mass Spectrometry; Oxazoles; Piperazines | 2003 |
[ON THE TOXICITY OF METHYLISOCYANATE AND ITS QUANTITATIVE DEERMINATION IN THE AIR].
Topics: Air Pollution; Animals; Cyanates; Guinea Pigs; Isocyanates; Lagomorpha; Mice; Necrosis; Pulmonary Edema; Rabbits; Rats; Research; Skin; Toxicology | 1964 |
Methyl isocyanate exposure and growth patterns of adolescents in Bhopal.
Topics: Accidents, Occupational; Adolescent; Anthropometry; Chemical Industry; Environmental Exposure; Epidemiologic Research Design; Female; Growth; Humans; India; Isocyanates; Male | 2003 |
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): II. Role of O6-alkylguanine-DNA alkyltransferase in cytotoxicity.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Neoplasm; Drug Synergism; Humans; Hydrazines; Isocyanates; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Transfection | 2004 |
Studies on the methyl isocyanate adducts with globin.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Dimethylformamide; Environmental Monitoring; Erythrocytes; Formamides; Globins; Humans; Hydrolysis; Isocyanates; Lysine; Pronase; Rats; Spectrometry, Mass, Electrospray Ionization; Valine | 2004 |
Revisiting the Bhopal tragedy.
Topics: Academies and Institutes; Accidents, Occupational; Antidotes; Biomedical Research; Chemical Industry; Cohort Studies; Disasters; Female; Gas Poisoning; Hospitals; Humans; India; Isocyanates; Male; Mutation; Neoplasms; Publishing; Pulmonary Surfactants; Thiosulfates | 2004 |
Long-delayed report on Bhopal disaster offers little new information.
Topics: Disasters; History, 20th Century; Humans; India; Isocyanates; Research; Time Factors | 2005 |
The Bhopal disaster and its aftermath: a review.
Topics: Accidents, Occupational; Chemical Industry; Deception; Developing Countries; Disasters; Environmental Exposure; Explosions; Gas Poisoning; Humans; India; Industry; Isocyanates; Liability, Legal; Urban Population | 2005 |
Excessive methaemoglobinaemia and multi-organ failure following 4-DMAP antidote therapy.
Topics: Adult; Antidotes; Blood Chemical Analysis; Chemical Industry; Combined Modality Therapy; Critical Illness; Follow-Up Studies; Humans; Isocyanates; Male; Methemoglobinemia; Multiple Organ Failure; Occupational Exposure; Pulmonary Gas Exchange; Risk Assessment; Treatment Outcome | 2005 |
Validation of a solvent-free sampler for the determination of low molecular weight aliphatic isocyanates under thermal degradation conditions.
Topics: Air Pollutants, Occupational; Automobiles; Chromatography, High Pressure Liquid; Cyanates; Environmental Monitoring; Hot Temperature; Humans; Isocyanates; Molecular Weight; Occupational Exposure; Paint; Piperazines; Risk Assessment; Solvents | 2005 |
The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activation.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biotransformation; Cell Line; Cells, Cultured; CHO Cells; Cricetinae; Drug Synergism; Guanine; HL-60 Cells; Humans; Hydrazines; Isocyanates; O(6)-Methylguanine-DNA Methyltransferase; Prodrugs; Sulfonamides; Transfection | 2005 |
Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry.
Topics: Air; Chromatography, Liquid; Cyanates; Diffusion; Fluorescence; Isocyanates; Molecular Weight; Oxazoles; Piperazines; Reproducibility of Results; Tandem Mass Spectrometry | 2006 |
Overseas experience in global health: travels to Bhopal, India, 20 years after the Union Carbide disaster.
Topics: Chemical Industry; Curriculum; Disasters; Education, Medical, Undergraduate; History, 20th Century; Humans; India; International Educational Exchange; Isocyanates; Students, Medical; United States | 2008 |
Aftermath of the Bhopal accident.
Topics: Accidents, Occupational; Chemical Industry; Humans; India; Isocyanates; Pesticides; Rehabilitation; Time Factors | 2008 |
Inflammatory response to isocyanates and onset of genomic instability in cultured human lung fibroblasts.
Topics: Apoptosis; Cell Line, Tumor; DNA Damage; Fibroblasts; Fluorescent Antibody Technique; Genomic Instability; Humans; Inflammation Mediators; Isocyanates; Lung; Time Factors | 2009 |
Respiratory symptoms and lung function in foundry workers exposed to low molecular weight isocyanates.
Topics: Adult; Air Pollutants, Occupational; Case-Control Studies; Cyanates; Eye Diseases; Female; Formaldehyde; Humans; Isocyanates; Male; Metallurgy; Middle Aged; Molecular Weight; Occupational Diseases; Occupational Exposure; Prevalence; Respiratory Function Tests; Respiratory Tract Diseases; Smoking; Sweden; Young Adult | 2009 |
In utero exposure to methyl isocyanate in the Bhopal gas disaster: evidence of persisting hyperactivation of immune system two decades later.
Topics: Antibodies, Antinuclear; Bhopal Accidental Release; Blood Cell Count; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Immune System; Immune System Diseases; Immunoglobulin Isotypes; India; Isocyanates; Lymphocytes; Maternal Exposure; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First | 2009 |
Induction of genomic instability in cultured human colon epithelial cells following exposure to isocyanates.
Topics: Antigens; Apoptosis; Cell Line; Colon; Cytokines; DNA Damage; Epithelial Cells; G2 Phase; Genomic Instability; Humans; Isocyanates; Karyotyping; Metaphase; Signal Transduction | 2009 |
Rats repeatedly exposed to toluene diisocyanate exhibit immune reactivity against methyl isocyanate-protein conjugates.
Topics: Administration, Inhalation; Animals; Asthma; Epitopes; Female; Humans; Immunoglobulin G; Isocyanates; Male; Multiprotein Complexes; Neutrophil Infiltration; Occupational Exposure; Rats; Rats, Inbred F344; Rats, Wistar; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Weight Gain | 2009 |
Bhopal Gas Tragedy: review of clinical and experimental findings after 25 years.
Topics: Abnormalities, Drug-Induced; Air Pollutants; Animals; Bhopal Accidental Release; Chronic Disease; DNA Damage; Eye Diseases; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Immune System Diseases; Inhalation Exposure; Isocyanates; Male; Maternal Exposure; Nervous System Diseases; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Tract Diseases | 2009 |
Effects of exposure of parents to toxic gases in Bhopal on the offspring.
Topics: Analysis of Variance; Anthropometry; Antisickling Agents; Body Height; Body Size; Body Weight; Chemical Hazard Release; Child, Preschool; Female; Growth Disorders; Health Status; Health Surveys; Humans; India; Infant; Infant Mortality; Infant, Newborn; Isocyanates; Male; Maternal Exposure; Paternal Exposure; Peak Expiratory Flow Rate; Pesticides; Pregnancy; Prenatal Exposure Delayed Effects; Puberty; Sex Factors; Stress, Physiological | 2010 |
Status of inflammatory biomarkers in the population that survived the Bhopal gas tragedy: a study after two decades.
Topics: Adult; Air Pollutants; Bhopal Accidental Release; Biomarkers; C-Reactive Protein; Environmental Exposure; Female; Humans; Inflammation Mediators; Interleukins; Isocyanates; Male; Middle Aged; Tumor Necrosis Factor-alpha | 2010 |
Bhopal. India launches new probe of cyanide disaster.
Topics: Academies and Institutes; Bhopal Accidental Release; Biotechnology; Disasters; Environmental Restoration and Remediation; Hospitals; Humans; India; Isocyanates | 2010 |
Molecular mechanisms of isocyanate induced oncogenic transformation in ovarian epithelial cells.
Topics: Animals; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Cellular Senescence; Chromosome Aberrations; Cytogenetic Analysis; DNA Damage; DNA Repair; Environmental Pollutants; Epithelial Cells; Female; In Situ Hybridization, Fluorescence; Isocyanates; Mice; Microsatellite Instability; Ovary; Ploidies; Telomeric Repeat Binding Protein 2 | 2010 |
Investigating genetic outcomes following 1984 Toxic Union Carbide disaster in India: epidemiological challenges.
Topics: Accidents, Occupational; Antisickling Agents; Disasters; Environmental Exposure; Epidemiologic Studies; History, 20th Century; Humans; India; Inhalation Exposure; Isocyanates; Mutation | 2010 |
Molecular surveillance of hepatitis and tuberculosis infections in a cohort exposed to methyl isocyanate.
Topics: Adult; Aged; Aged, 80 and over; Air Pollutants; Bhopal Accidental Release; Cohort Studies; DNA, Bacterial; DNA, Viral; Female; Hepacivirus; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis C; Hepatitis C Antibodies; Humans; India; Isocyanates; Male; Middle Aged; Molecular Epidemiology; Mycobacterium tuberculosis; RNA, Viral; Tuberculosis | 2011 |
Cell cycle deregulation by methyl isocyanate: Implications in liver carcinogenesis.
Topics: Animals; Carcinogenesis; Cell Cycle; Cell Cycle Proteins; Cell Line; Chromosome Aberrations; DNA Damage; Epithelial Cells; Isocyanates; Liver; Mice | 2014 |
Retrospective analysis of lung function abnormalities of Bhopal gas tragedy affected population.
Topics: Accidents, Occupational; Adolescent; Adult; Age Factors; Child; Disasters; Female; Gases; Humans; Isocyanates; Lung; Male; Middle Aged; Retrospective Studies; Spirometry | 2012 |
Cancer morbidity among methyl isocyanate exposed long- term survivors and their offspring: a hospital-based five year descriptive study (2006 - 2011) and future directions to predict cancer risk in the affected population.
Topics: Adolescent; Adult; Aged; Antisickling Agents; Child; Child, Preschool; Family; Female; Follow-Up Studies; Humans; Incidence; Infant; Infant, Newborn; Isocyanates; Male; Middle Aged; Morbidity; Neoplasms; Prognosis; Survival Rate; Survivors; Young Adult | 2011 |
Bhopal atmospheric dispersion revisited.
Topics: Aerosols; Air Pollutants; Bhopal Accidental Release; Gravitation; India; Isocyanates; Models, Theoretical; Wind | 2012 |
[Determination of methyl isocyanate (MIC) in air of workplaces by HPLC].
Topics: Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Environmental Monitoring; Isocyanates; Workplace | 2012 |
Bhopal methyl isocyanate affected population and cancer susceptibility: where do we stand now?
Topics: Antisickling Agents; Bhopal Accidental Release; Disease Susceptibility; Humans; India; Isocyanates; Neoplasms; Prognosis; Risk Factors | 2012 |
Methyl isocyanate exposure and atypical lymphocytes.
Topics: Bhopal Accidental Release; Chemical Industry; Disasters; Environmental Exposure; History, 20th Century; Humans; India; Isocyanates; Lymphocytes; Occupational Exposure | 2013 |
Imbalance of mitochondrial-nuclear cross talk in isocyanate mediated pulmonary endothelial cell dysfunction.
Topics: Apoptosis; Cell Line; Cell Nucleus; DNA Damage; Endothelial Cells; Gene Expression Regulation; Humans; Isocyanates; Mitochondria; Pulmonary Artery; Reactive Oxygen Species | 2013 |
In silico interaction of methyl isocyanate with immune protein responsible for Mycobacterium tuberculosis infection using molecular docking.
Topics: CD40 Ligand; Glutathione Synthase; Humans; Immune System; Integrin alpha5beta1; Isocyanates; Lung Neoplasms; Molecular Docking Simulation; p38 Mitogen-Activated Protein Kinases; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein D; Tuberculosis; Urokinase-Type Plasminogen Activator | 2016 |
Bhopal study represents "missed opportunity".
Topics: Bhopal Accidental Release; Biomedical Research; Disasters; Humans; India; Isocyanates; Lost to Follow-Up; Morbidity | 2013 |
Gas-phase reaction of methyl isothiocyanate and methyl isocyanate with hydroxyl radicals under static relative rate conditions.
Topics: Fungicides, Industrial; Hydroxyl Radical; Isocyanates; Isothiocyanates; Kinetics; Phase Transition; Soil Pollutants | 2014 |
Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
Topics: Animals; Antineoplastic Agents; Biocatalysis; Carbamates; Cattle; Cell Death; Cells, Cultured; Endothelial Cells; Humans; Hydrazines; Immunoblotting; Isocyanates; MAP Kinase Kinase Kinase 5; Mitogen-Activated Protein Kinase 8; Neovascularization, Physiologic; Signal Transduction; Sulfonamides; Thioredoxin Reductase 1; Thioredoxins | 2014 |
Determination of methyl isocyanate in outdoor residential air near metam-sodium soil fumigations.
Topics: Acrylic Resins; Agrochemicals; Air Pollutants; California; Environmental Monitoring; Fumigation; Humans; Inhalation Exposure; Isocyanates; Maximum Allowable Concentration; Pesticides; Polystyrenes; Seasons; Soil; Thiocarbamates; Washington | 2014 |
Bhopal's legacy: three decades on and residents are still being poisoned.
Topics: Bhopal Accidental Release; Compensation and Redress; Disasters; Drug Industry; Gas Poisoning; Humans; India; Isocyanates; Pesticides; Survivors | 2014 |
Increased micronucleus frequency in peripheral blood lymphocytes contributes to cancer risk in the methyl isocyanate-affected population of Bhopal.
Topics: Adolescent; Adult; Alcohol Drinking; Bhopal Accidental Release; Case-Control Studies; Cell Nucleus Division; Child; Environmental Exposure; Female; Humans; India; Isocyanates; Life Style; Lymphocytes; Male; Maternal Exposure; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Neoplasms; Paternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Sex Factors; Smoking; Survivors; Tobacco, Smokeless; Young Adult | 2015 |
Insights from the Molecular Docking of Hydrolytic Products of Methyl Isocyanate (MIC) to Inhibition of Human Immune Proteins.
Topics: Amino Acids; Catalytic Domain; Humans; Hydrolysis; Immune System; Isocyanates; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Proteins | 2015 |
In silico docking of methyl isocyanate (MIC) and its hydrolytic product (1, 3-dimethylurea) shows significant interaction with DNA Methyltransferase 1 suggests cancer risk in Bhopal-Gas- Tragedy survivors.
Topics: Binding Sites; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Environmental Exposure; Humans; India; Isocyanates; Methylurea Compounds; Molecular Docking Simulation; Neoplasms; Protein Binding; Protein Structure, Tertiary | 2015 |
On the long-term effects of methyl isocyanate on cell-mediated immunity in Bhopal gas-exposed long-term survivors and their offspring.
Topics: Adolescent; Adult; Bhopal Accidental Release; Biomarkers; Child; Female; Gas Poisoning; Humans; Immunity, Cellular; Immunosuppressive Agents; India; Inhalation Exposure; Isocyanates; Lymphocytosis; Male; Maternal Exposure; Middle Aged; Neoplasms; Paternal Exposure; Pesticides; Pulmonary Disease, Chronic Obstructive; Risk; Sex Factors; Survivors; Young Adult | 2017 |
Spectrum of health condition in methyl isocyanate (MIC)-exposed survivors measured after 30 years of disaster.
Topics: Bhopal Accidental Release; Disasters; Environmental Exposure; Female; Health Status Indicators; Humans; Incidence; India; Isocyanates; Life Style; Male; Middle Aged; Morbidity; Neoplasms; Prevalence; Reproduction; Survivors | 2018 |
Automated 3D segmentation of methyl isocyanate-exposed rat trachea using an ultra-thin, fully fiber optic optical coherence endoscopic probe.
Topics: Algorithms; Animals; Endoscopy; Imaging, Three-Dimensional; Isocyanates; Male; Rats; Rats, Sprague-Dawley; Tomography, Optical Coherence; Trachea | 2018 |
Determination of methyl isopropyl hydantoin from rat erythrocytes by gas-chromatography mass-spectrometry to determine methyl isocyanate dose following inhalation exposure.
Topics: Animals; Erythrocytes; Gas Chromatography-Mass Spectrometry; Hydantoins; Inhalation Exposure; Isocyanates; Limit of Detection; Liquid-Liquid Extraction; Rats; Reproducibility of Results; Toxicity Tests | 2018 |
Enzymatic one-step ring contraction for quinolone biosynthesis.
Topics: Alkaloids; Aspergillus nidulans; Binding Sites; Biosynthetic Pathways; Carbon Dioxide; Cloning, Molecular; Crystallography, X-Ray; Cyclization; Escherichia coli; Fungal Proteins; Gene Expression; Genetic Vectors; Hemocyanins; Hydroxyquinolines; Isocyanates; Kinetics; Methylamines; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Quinolones; Recombinant Proteins; Substrate Specificity; Zinc | 2018 |
Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats.
Topics: Animals; Blood Coagulation; Dose-Response Relationship, Drug; Hypoxia; Inhalation Exposure; Isocyanates; Male; Oxygen; Rats; Rats, Sprague-Dawley; Thromboplastin | 2019 |
Exposure index of methyl isocyanate (MIC) gas disaster and a comprehensive spectrum of cytogenetic analysis after 30 years.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chromosome Aberrations; Cytogenetic Analysis; Disasters; Environmental Exposure; Female; Follow-Up Studies; Humans; India; Isocyanates; Lymphocytes; Male; Middle Aged; Mutagens; Sex Factors | 2019 |
Alleviation of methyl isocyanate-induced airway obstruction and mortality by tissue plasminogen activator.
Topics: Airway Obstruction; Animals; Disease Models, Animal; Isocyanates; Male; Rats; Rats, Sprague-Dawley; Tissue Plasminogen Activator | 2020 |
Quantitative Risk Assessment: Developing a Bayesian Approach to Dichotomous Dose-Response Uncertainty.
Topics: Bayes Theorem; Dose-Response Relationship, Drug; Isocyanates; Nitrosamines; Risk Assessment; Uncertainty | 2020 |
Susceptibility of the Bhopal-methyl isocyanate (MIC)-gas-tragedy survivors and their offspring to COVID-19: What we know, what we don't and what we should?
Topics: Betacoronavirus; Communicable Disease Control; Coronavirus Infections; COVID-19; Disasters; Disease Susceptibility; Environmental Exposure; Humans; Immunocompromised Host; India; Isocyanates; Pandemics; Pneumonia, Viral; SARS-CoV-2; Self Care; Survivors; Vulnerable Populations | 2020 |
Characterization of US population levels of urinary methylcarbamoyl mercapturic acid, a metabolite of N,N-dimethylformamide and methyl isocyanate, in the National Health and Nutrition Examination Survey (NHANES) 2005-2006 and 2011-2016.
Topics: Acetylcysteine; Biomarkers; Child; Cotinine; Dimethylformamide; Humans; Isocyanates; Nutrition Surveys; Tobacco Smoke Pollution | 2021 |
Spectrum of stable and unstable rearrangements in lymphocytic chromosomes investigated in Bhopal population 30 years post MIC disaster amid co-exposure to lifestyle, living, and occupational hazards.
Topics: Chromosome Aberrations; Chromosomes; Disasters; Humans; Isocyanates; Life Style | 2023 |
Identification and determination of phenyl methyl carbamate released from adducted hemoglobin for methyl isocyanate exposure verification.
Topics: Animals; Biomarkers; Carbamates; Hemoglobins; Isocyanates; Pesticides; Phenols; Pronase; Rats; Tyrosine | 2022 |