cvt 124 has been researched along with furosemide in 5 studies
| Studies (cvt 124) | Trials (cvt 124) | Recent Studies (post-2010) (cvt 124) | Studies (furosemide) | Trials (furosemide) | Recent Studies (post-2010) (furosemide) |
|---|---|---|---|---|---|
| 18 | 2 | 0 | 13,631 | 1,358 | 2,486 |
| Protein | Taxonomy | cvt 124 (IC50) | furosemide (IC50) |
|---|---|---|---|
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Homo sapiens (human) | 3.76 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Mus musculus (house mouse) | 3.76 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, DP; DeWolf, R; Fletcher, T; Gellai, M; Ruffolo, RR; Schreiner, GF | 1 |
| Beckman, E; Bennett, D; Cines, M; Fisher, ML; Freudenberger, R; Gladwell, T; Gottlieb, SS; Liittschwager, EB; Marshall, J; Skettino, SL; Wolff, A | 1 |
| Herzer, WA; Jackson, EK; Kost, CK; Smits, GJ; Tofovic, SP | 1 |
| Abraham, WT; Beckman, E; Bennett, D; Bourge, R; Brater, DC; Dyer, F; Goldman, S; Gomez, M; Gottlieb, SS; Havranek, E; Thomas, I; Ticho, B | 1 |
| Gottlieb, SS | 1 |
1 review(s) available for cvt 124 and furosemide
| Article | Year |
|---|---|
Adenosine A1 antagonists and the cardiorenal syndrome.
Topics: Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Furosemide; Glomerular Filtration Rate; Heart Failure; Humans; Kidney Diseases; Kidney Function Tests; Male; Mice; Prognosis; Randomized Controlled Trials as Topic; Receptor, Adenosine A1; Risk Assessment; Severity of Illness Index; Syndrome; Treatment Outcome; Xanthines | 2008 |
2 trial(s) available for cvt 124 and furosemide
| Article | Year |
|---|---|
Effects of BG9719 (CVT-124), an A1-adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure.
Topics: Adult; Aged; Diuretics; Double-Blind Method; Female; Furosemide; Glomerular Filtration Rate; Heart Failure; Humans; Kidney Function Tests; Male; Middle Aged; Natriuresis; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Water-Electrolyte Balance; Xanthines | 2000 |
BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Cross-Over Studies; Diuresis; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Electrolytes; Female; Furosemide; Glomerular Filtration Rate; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Purinergic P1 Receptor Antagonists; Sodium; Urinalysis; Xanthines | 2002 |
2 other study(ies) available for cvt 124 and furosemide
| Article | Year |
|---|---|
CVT-124, a novel adenosine A1 receptor antagonist with unique diuretic activity.
Topics: Animals; Diuretics; Dose-Response Relationship, Drug; Furosemide; Glomerular Filtration Rate; Hydrochlorothiazide; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renal Circulation; Xanthines | 1998 |
A(1) receptor blockade induces natriuresis with a favorable renal hemodynamic profile in SHHF/Mcc-fa(cp) rats chronically treated with salt and furosemide.
Topics: Animals; Furosemide; Hemodynamics; Hypertension; Kidney Function Tests; Metabolic Clearance Rate; Natriuresis; Purinergic P1 Receptor Antagonists; Rats; Sodium Chloride; Xanthines | 2001 |