cv 3988 has been researched along with thiazoles in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (92.59) | 18.7374 |
| 1990's | 4 (7.41) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adler, KB; Akley, NJ; Glasgow, WC | 1 |
| Fukushi, K; Ishitani, K; Ishitani, M; Mikami, T; Suzuki, M; Suzuki, S | 1 |
| Cox, CP | 1 |
| Fukuzawa, K; Takauchi, K; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, J | 1 |
| Hayashi, M; Kimura, J; Nomura, H; Oh-Ishi, S; Tsushima, S | 1 |
| Imura, Y; Nishikawa, K; Terashita, Z | 2 |
| Hayashi, H; Inoue, K; Kudo, I; Nojima, S; Nomura, H; Onozaki, K; Tsushima, S | 1 |
| Beattie, TR; Biftu, T; Hwang, SB; Lam, MH; Shen, TY | 1 |
| Imura, Y; Nishikawa, K; Sumida, S; Terashita, Z | 2 |
| Tokumura, A; Tsukatani, H | 1 |
| Deacon, RW; Farley, C; Handley, DA; Saunders, RN | 1 |
| Chang, SW; Henson, PM; McMurtry, IF; Pfeffer, KD; Voelkel, NF; Worthen, SG | 1 |
| Hwang, SB; Lam, MH | 1 |
| Benveniste, J; Braquet, P; Chignard, M; Korth, R; Le Couedic, JP; Norel, X; Nunez, D; Spinnewyn, B | 1 |
| Adnot, S; Joseph, D; Vargaftig, BB | 1 |
| Imura, Y; Nishikawa, K; Shino, A; Terashita, Z | 1 |
| Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugidachi, A; Tsurufuji, S; Watanabe, M | 1 |
| Lagente, V; Steel, G; Vargaftig, B; Wallace, JL; Whittle, BJ | 1 |
| Adachi, M; Imai, T; Kamiya, I; Kobayashi, H; Nishikata, H; Okazawa, A; Satoh, H; Takahashi, T; Yamaguchi, H | 1 |
| Grue-Sørensen, G; Nielsen, CK; Nielsen, IM | 1 |
| Cirino, M; Desquand, S; Hadvary, P; Lagente, V; Lefort, J; Lellouch-Tubiana, A; Vargaftig, BB | 1 |
| Bray, MA; Steiger, J; Subramanian, N | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Steel, G; Wallace, JL; Whittle, BJ | 1 |
| Hahn, HL; Hansen, D; Lang, M | 1 |
| Chang, SW; Feddersen, CO; Henson, PM; Voelkel, NF | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Malo, PE; Pfeiffer, DF; Wasserman, MA | 1 |
| Fukuzawa, K; Okasaka, N; Tokumura, A; Tsukatani, H; Yoshida, J | 1 |
| Cox, CP; Wood, KL | 1 |
| Fukuzawa, K; Maruyama, T; Tokumura, A; Tsukatani, H; Yoshida, J | 1 |
| Baggiolini, M; Dewald, B | 1 |
| Genovese, A; Levi, R; Robertson, DA | 1 |
| Robertson, DN; Smith, GM | 1 |
| Wallace, JL; Whittle, BJ | 1 |
| Buxton, DB; Hanahan, DJ; Olson, MS | 1 |
| Alloatti, G; Benedetto, C; Camussi, G; Emanuelli, G; Massobrio, M; Montrucchio, G; Roffinello, C; Tetta, C | 1 |
| Alloatti, G; Camussi, G; Emanuelli, G; Montrucchio, G; Roffinello, C; Tetta, C | 1 |
| Mikulaschek, AW; Toth, PD | 1 |
| Oda, M; Saito, K; Satouchi, K; Yasunaga, K | 1 |
| Hayashi, M; Nomura, H; Oh-ishi, S; Tsushima, S; Yamaki, K | 1 |
| Hanahan, DJ; Homma, H; Tokumura, A | 1 |
| Kogo, H; Matsudaira, T; Satoh, T | 1 |
| Shukla, SD | 1 |
| Issekutz, AC; Szpejda, M | 1 |
| Valone, FH | 1 |
| Handley, DA; Lee, ML; Saunders, RN | 1 |
| Kumahara, Y; Masugi, F; Ogihara, T; Otsuka, A; Saeki, S | 2 |
| Inada, Y; Nishikawa, K; Nomura, H; Terashita, Z; Tsushima, S; Yoshioka, Y | 1 |
| Aglietta, M; Arese, M; Bussolino, F; Camussi, G; Costamagna, C; Garbarino, G; Pescarmona, G; Sanavio, F; Silvagno, F; Soldi, R | 1 |
| Akiyama, M; Ino, M; Miwa, M; Shimura, M; Sugatani, J; Suzuki, M; Suzuki, Y; Yamazaki, R | 1 |
1 review(s) available for cv 3988 and thiazoles
| Article | Year |
|---|---|
[Antagonists of platelet activating factor].
Topics: Animals; Benzofurans; Benzopyrans; Depression, Chemical; Guinea Pigs; Lignans; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Thiazoles | 1985 |
53 other study(ies) available for cv 3988 and thiazoles
| Article | Year |
|---|---|
Platelet-activating factor provokes release of mucin-like glycoproteins from guinea pig respiratory epithelial cells via a lipoxygenase-dependent mechanism.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Epithelium; Glyceryl Ethers; Guinea Pigs; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Mucins; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Trachea | 1992 |
Induction of platelet-activating factor in mice by intravenous administration of a neutral fraction of bakers' yeast mannan.
Topics: Albuterol; Animals; Bile; Blood Pressure; Chromatography, Ion Exchange; Hypotension; Mannans; Mice; Mice, Inbred Strains; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Saccharomyces cerevisiae; Thiazoles | 1991 |
Effects of CV-3988, an antagonist of platelet-activating factor (PAF), on washed rabbit platelets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Epoprostenol; Female; Osmolar Concentration; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thiazoles | 1986 |
A platelet-aggregating and hypotensive phospholipid isolated from bovine brain.
Topics: Animals; Blood Pressure; Brain Chemistry; Cattle; Diazomethane; In Vitro Techniques; Phospholipid Ethers; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1986 |
Characterization of the activity of a platelet activating factor antagonist, CV-3988.
Topics: Alprazolam; Animals; Autacoids; Blood Pressure; Capillary Permeability; Dose-Response Relationship, Drug; Male; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin; Thiazoles | 1987 |
Inhibition by CV-3988 of the binding of [3H]-platelet activating factor (PAF) to the platelet.
Topics: Animals; Blood Platelets; Depression, Chemical; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Species Specificity; Thiazoles; Tritium | 1985 |
Activation of guinea pig peritoneal macrophages by platelet activating factor (PAF) and its agonists.
Topics: Animals; Blood Platelets; Female; Guinea Pigs; In Vitro Techniques; Macrophages; Peritoneal Cavity; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 1985 |
trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.
Topics: Animals; Benzofurans; Benzopyrans; Blood Platelets; Bradykinin; Capillary Permeability; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Furans; Histamine; Humans; Lignans; Magnesium; Mathematics; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sodium; Thiazoles | 1985 |
Beneficial effects of (RS)-2-methoxy-3-(octadecylcarbamoyloxy)propyl 2-(3-thiazolio)ethyl phosphate, a specific PAF antagonist, in endotoxin and anaphylactic shock.
Topics: Anaphylaxis; Animals; Blood Platelets; Hypotension; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Thiazoles | 1985 |
Evidence for distinct systemic extravasation effects of platelet activating factor, leukotrienes B4, C4, D4 and histamine in the guinea pig.
Topics: Animals; Chromones; Diphenhydramine; Dose-Response Relationship, Drug; Guinea Pigs; Hematocrit; Hemorrhage; Histamine; Injections, Intravenous; Leukotriene B4; Male; Phospholipid Ethers; Plasma; Platelet Activating Factor; SRS-A; Thiazoles; Time Factors | 1986 |
PAF antagonists: different effects on platelets, neutrophils, guinea pig ileum and PAF-induced vasodilation in isolated rat lung.
Topics: Alprazolam; Angiotensin II; Animals; Blood Platelets; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Muscle Contraction; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Artery; Pulmonary Circulation; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; SRS-A; Thiazoles; Vasodilation | 1986 |
Species difference in the specific receptors of platelet activating factor.
Topics: Animals; Benzofurans; Blood Platelets; Cell Membrane; Diterpenes; Furans; Ginkgolides; Humans; Lactones; Lignans; Lung; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Species Specificity; Thiazoles; Thiophenes | 1986 |
Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Benzofurans; Benzopyrans; Blood Platelets; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Lignans; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thiazoles | 1986 |
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Lectins, C-Type; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Pyridines; Thiazoles; Thrombin | 1987 |
A lethal role of platelet activating factor in anaphylactic shock in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Dexamethasone; Male; Mice; Mice, Inbred Strains; Naloxone; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; SRS-A; Thiazoles | 1987 |
Platelet-activating factor in the inflammatory exudate in the anaphylactic phase of allergic inflammation in rats.
Topics: Adenosine Diphosphate; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Exudates and Transudates; Inflammation; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.
Topics: Animals; Blood Pressure; Disease Models, Animal; Diterpenes; Escherichia coli Infections; Ethanol; Ginkgolides; Glyceryl Ethers; Intestine, Small; Lactones; Lipopolysaccharides; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach; Thiazoles | 1987 |
[The effect of a specific antagonist of PAF (CV-3988) on airway hyperresponsiveness induced by ozone exposure in beagles].
Topics: Animals; Bronchi; Dogs; Female; Methacholine Chloride; Methacholine Compounds; Ozone; Phospholipid Ethers; Platelet Activating Factor; Thiazoles; Thromboxane B2 | 1987 |
Derivatives of 2-methylenepropane-1,3-diol as new antagonists of platelet activating factor.
Topics: Animals; Blood Pressure; Bronchi; Female; Guinea Pigs; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles | 1988 |
Interference of the Paf antagonist Ro 19-3704 with Paf and antigen-induced bronchoconstriction in the guinea-pig.
Topics: Aerosols; Animals; Blood Cell Count; Bronchodilator Agents; Female; Glyceryl Ethers; Guinea Pigs; In Vitro Techniques; Macrophage Activation; Macrophages; Male; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Alveoli; Thiazoles | 1988 |
Platelet activating factor (PAF) is a potent stimulator of porcine tracheal fluid secretion in vitro.
Topics: Animals; Body Fluids; In Vitro Techniques; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Swine; Thiazoles; Trachea | 1987 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Gastrointestinal plasma leakage in endotoxic shock. Inhibition by prostaglandin E2 and by a platelet-activating factor antagonist.
Topics: Animals; Blood Pressure; Blood Proteins; Digestive System; Dinoprostone; Male; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Shock, Septic; Thiazoles | 1987 |
Effects of the PAF-antagonist CV-3988 on PAF-induced changes in mucus secretion and in respiratory and circulatory variables in ferrets.
Topics: Animals; Asthma; Blood Cells; Ferrets; Mucus; Phospholipid Ethers; Platelet Activating Factor; Thiazoles | 1987 |
Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats.
Topics: Animals; Blood Pressure; Endotoxins; Hemodynamics; Lung; Male; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Circulation; Quinolinium Compounds; Rats; Rats, Inbred Strains; Salmonella enteritidis; Thiazoles; Time Factors; Vasoconstriction; Vinblastine | 1987 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Enhancement of leukotriene D4-induced contraction of guinea-pig isolated trachea by platelet activating factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Guinea Pigs; In Vitro Techniques; Male; Meclofenamic Acid; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; SRS-A; Thiazoles; Trachea | 1987 |
Platelet aggregation induced by ether-linked phospholipids. 2. Mechanism of desensitization of rabbit platelets by platelet activating factor and reversibility of inhibitory actions of its antagonists.
Topics: Animals; In Vitro Techniques; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin, Bovine; Structure-Activity Relationship; Thiazoles | 1987 |
Selective antagonism of platelet-activating factor (PAF)-induced aggregation and secretion in washed rabbit platelets by CV-3988, L-652731, triazolam and alprazolam.
Topics: Alprazolam; Animals; Blood Platelets; Furans; In Vitro Techniques; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thiazoles; Triazolam | 1987 |
Platelet aggregation induced by ether-linked phospholipids. 1. Inhibitory actions of bovine serum albumin and structural analogues of platelet activating factor.
Topics: Animals; Cats; Cattle; Ethers; Humans; Lysophospholipids; Phosphatidic Acids; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin, Bovine; Structure-Activity Relationship; Thiazoles | 1987 |
Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay.
Topics: Benzofurans; Diterpenes; Exocytosis; Fluorescence; Ginkgolides; Humans; Lactones; Lignans; Methods; Neutrophils; Pancreatic Elastase; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Pyridines; Thiazoles | 1987 |
Negative inotropic effect of platelet-activating factor on human myocardium: a pharmacological study.
Topics: Calcium; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Indomethacin; Myocardial Contraction; Phospholipid Ethers; Platelet Activating Factor; Quinolinium Compounds; SRS-A; Thiazoles | 1987 |
CV3988 inhibits in vivo platelet aggregation induced by PAF-acether and collagen.
Topics: Animals; Blood Pressure; Collagen; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Rabbits; Rats; Species Specificity; Thiazoles; Thromboxane B2; Time Factors | 1986 |
Prevention of endotoxin-induced gastrointestinal damage by CV-3988, an antagonist of platelet-activating factor.
Topics: Animals; Blood Pressure; Endotoxins; Lipopolysaccharides; Male; Peptic Ulcer; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella typhi; Thiazoles | 1986 |
Possible role of platelet activating factor (PAF) in disseminated intravascular coagulation (DIC), evidenced by use of a PAF antagonist, CV-3988.
Topics: Animals; Disseminated Intravascular Coagulation; Endotoxins; Phospholipid Ethers; Platelet Activating Factor; Rats; Thiazoles | 1986 |
Specific antagonists of platelet activating factor-mediated vasoconstriction and glycogenolysis in the perfused rat liver.
Topics: Animals; Dose-Response Relationship, Drug; Glucose; Liver; Liver Glycogen; Male; Perfusion; Phenylephrine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Thiazoles; Vasoconstriction; Venous Pressure | 1986 |
Platelet-activating factor contracts human myometrium in vitro.
Topics: Adult; Chromones; Female; Humans; In Vitro Techniques; Myometrium; Oxytocin; Phospholipid Ethers; Platelet Activating Factor; Pregnancy; Thiazoles; Uterine Contraction | 1986 |
In vitro contractile effect of platelet-activating factor on guinea-pig myometrium.
Topics: Animals; Chromones; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Myometrium; Oxytocin; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins; Thiazoles; Uterine Contraction | 1986 |
Effects of a platelet-activating factor antagonist, CV-3988, on different shock models in the rat.
Topics: Animals; Blood Pressure; Decerebrate State; Male; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Shock, Hemorrhagic; Shock, Septic; Thiazoles | 1986 |
Polymorphonuclear leukocyte-platelet interactions: acetylglyceryl ether phosphocholine-induced platelet activation under stimulation with chemotactic peptide.
Topics: Animals; Blood Platelets; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thiazoles | 1986 |
Suppression of phorbol myristate acetate-induced pleurisy by CV-3988, an antagonist of platelet-activating factor.
Topics: Animals; Male; Phospholipid Ethers; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thiazoles | 1986 |
Structural analogs of alkylacetylglycerophosphocholine inhibitory behavior on platelet activation.
Topics: Animals; Blood Platelets; Kinetics; Phosphatidic Acids; Phosphatidylinositols; Phospholipid Ethers; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thiazoles | 1985 |
A possible role of antihypertensive polar renomedullary lipid (APRL) and prostaglandin E2 in the kidney in the antihypertensive action of pindolol.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dinoprostone; Electrolytes; Indomethacin; Kidney; Male; Phospholipid Ethers; Pindolol; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred SHR; Thiazoles | 1985 |
Platelet activating factor-stimulated formation of inositol triphosphate in platelets and its regulation by various agents including Ca2+, indomethacin, CV-3988, and forskolin.
Topics: Animals; Blood Platelets; Calcium; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Indomethacin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Sugar Phosphates; Thiazoles; Time Factors | 1985 |
Evidence that platelet activating factor may mediate some acute inflammatory responses. Studies with the platelet-activating factor antagonist, CV3988.
Topics: Acute Disease; Animals; Blood Platelets; Capillary Permeability; Cell Movement; Inflammation; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Regional Blood Flow; Serum Albumin; Skin; Thiazoles; Thrombocytopenia | 1986 |
Inhibition of binding of the platelet-activating factor AGEPC to platelets by the AGEPC analog rac-3-(N-n-octadecylcarbamoyloxy)-2-methoxypropyl 2-thiazolioethyl phosphate (CV-3988).
Topics: Blood Platelets; Dose-Response Relationship, Drug; Humans; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Thiazoles | 1985 |
Is platelet activating factor (PAF) a mediator of endotoxin shock?
Topics: Animals; Blood Pressure; Endotoxins; Male; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Thiazoles | 1985 |
Evidence for a direct effect on vascular permeability of platelet-activating factor induced hemoconcentration in the guinea pig.
Topics: Animals; Calcium Channel Blockers; Capillary Permeability; Guinea Pigs; Hematocrit; Histamine; Male; Phospholipid Ethers; Platelet Activating Factor; Thiazoles; Thromboxane-A Synthase | 1985 |
The role of antihypertensive polar renomedullary lipid in the pathogenesis of hypertension.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dinoprostone; Dogs; Epoprostenol; Female; Histamine; Hypertension, Renal; Kidney; Kidney Medulla; Male; Norepinephrine; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; Thiazoles | 1984 |
CV-3988 - a specific antagonist of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcimycin; Collagen; Dose-Response Relationship, Drug; Male; Micelles; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1983 |
Effect of 1-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine inhibitor on the reduction of one-kidney, one clip hypertension after unclipping in the rat.
Topics: Animals; Blood Pressure; Hypertension, Renovascular; Male; Phospholipid Ethers; Platelet Activating Factor; Rats; Renal Artery; Thiazoles | 1984 |
Human endothelial cells are targets for platelet-activating factor (PAF). Activation of alpha and beta protein kinase C isozymes in endothelial cells stimulated by PAF.
Topics: Actins; Amino Acid Sequence; Antibodies; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Cytoskeletal Proteins; Cytosol; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Ginkgolides; Humans; Isoenzymes; Kinetics; Lactones; Molecular Sequence Data; Naphthalenes; Peptides; Phospholipid Ethers; Platelet Activating Factor; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thiazoles; Vinculin | 1994 |
Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.
Topics: Animals; Azepines; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Neutrophils; P-Selectin; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Triazoles | 1998 |