cv 159 has been researched along with nicardipine in 3 studies
*Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [MeSH]
*Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [MeSH]
Studies (cv 159) | Trials (cv 159) | Recent Studies (post-2010) (cv 159) | Studies (nicardipine) | Trials (nicardipine) | Recent Studies (post-2010) (nicardipine) |
---|---|---|---|---|---|
8 | 0 | 0 | 2,646 | 444 | 312 |
Protein | Taxonomy | cv 159 (IC50) | nicardipine (IC50) |
---|---|---|---|
Bile salt export pump | Homo sapiens (human) | 8.314 | |
ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 8 | |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 4.2992 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 0.42 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 1.69 | |
ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 2.5 | |
Cytochrome P450 2J2 | Homo sapiens (human) | 1.69 | |
Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 4.925 | |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 4.8 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hidaka, H; Nunoki, K; Taira, N; Tanaka, T; Umekawa, H; Yamakawa, K | 1 |
Imai, H; Imai, S; Matsui, K; Nakagawa, Y; Nakazawa, M; Ochi, S | 1 |
Fujii, Y; Kamibayashi, M; Miyazaki, H; Nagashima, K; Nomura, Y; Okuma, Y; Shimizu, K; Tanaka, S; Uehara, T | 1 |
3 other study(ies) available for cv 159 and nicardipine
Article | Year |
---|---|
Inhibition of calmodulin function by CV-159, a novel dihydropyridine compound.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Calcium; Calmodulin; Cattle; Dansyl Compounds; Dihydropyridines; Myosin-Light-Chain Kinase; Nicardipine | 1988 |
Effects of the new dihydropyridine derivative 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester on the cardiohemodynamics and the energy metabolism of ischemic myocardium.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Coronary Circulation; Coronary Disease; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Energy Metabolism; Esters; Female; Heart; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Nicardipine; Rats | 1987 |
Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury.
Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cerebral Infarction; Dihydropyridines; Hemodynamics; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Neuroprotective Agents; Nicardipine; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Water | 1999 |