cv 159 has been researched along with dihydropyridines in 8 studies
| Studies (cv 159) | Trials (cv 159) | Recent Studies (post-2010) (cv 159) | Studies (dihydropyridines) | Trials (dihydropyridines) | Recent Studies (post-2010) (dihydropyridines) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 5,022 | 529 | 969 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hidaka, H; Nunoki, K; Taira, N; Tanaka, T; Umekawa, H; Yamakawa, K | 1 |
| Imai, H; Imai, S; Matsui, K; Nakagawa, Y; Nakazawa, M; Ochi, S | 1 |
| Fujii, Y; Kamibayashi, M; Miyazaki, H; Nagashima, K; Nomura, Y; Okuma, Y; Shimizu, K; Tanaka, S; Uehara, T | 1 |
| Asakura, T; Asano, T; Ishiuchi, A; Jinnouchi, Y; Kamibayashi, M; Kobayashi, HP; Koizumi, S; Kubota, S; Nakano, H; Oowada, S; Otsubo, T; Shimamura, T; Watanabe, T | 1 |
| Hirayama, A; Kamibayashi, M; Kobayashi, HP; Nagase, S; Oowada, S; Otsubo, T; Watanabe, T | 1 |
| Hataji, K; Ishiuchi, A; Kamibayashi, M; Kawakami, H; Kobayashi, S; Kumai, T; Murakami, E; Nagaya, M; Nakano, H; Oowada, S; Otsubo, T; Watanabe, T | 1 |
| Hara, Y; Kamibayashi, M; Okada, M; Usui, T; Yamawaki, H | 2 |
8 other study(ies) available for cv 159 and dihydropyridines
| Article | Year |
|---|---|
Inhibition of calmodulin function by CV-159, a novel dihydropyridine compound.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Calcium; Calmodulin; Cattle; Dansyl Compounds; Dihydropyridines; Myosin-Light-Chain Kinase; Nicardipine | 1988 |
Effects of the new dihydropyridine derivative 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester on the cardiohemodynamics and the energy metabolism of ischemic myocardium.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Coronary Circulation; Coronary Disease; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Energy Metabolism; Esters; Female; Heart; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Nicardipine; Rats | 1987 |
Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury.
Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cerebral Infarction; Dihydropyridines; Hemodynamics; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Neuroprotective Agents; Nicardipine; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Water | 1999 |
The role of the new Ca2+ antagonist, CV159, in hepatic I/R injury-the evaluation of hepatic organ reducing activity using in vivo and ex vivo EPR.
Topics: Alanine Transaminase; Animals; Calcium; Calmodulin; Dihydropyridines; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Liver; Male; Mitochondria; Myosin-Light-Chain Kinase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Survival Rate | 2008 |
Effect of CV159-Ca(2+)/calmodulin blockade on redox status hepatic ischemia-reperfusion injury in mice evaluated by a newly developed in vivo EPR imaging technique.
Topics: Alanine Transaminase; Animals; Calcium; Calmodulin; Dihydropyridines; Electron Spin Resonance Spectroscopy; Immunohistochemistry; Liver; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Oxidation-Reduction; Reperfusion Injury; Superoxide Dismutase; Superoxide Dismutase-1 | 2008 |
Effects of a calcium-channel blocker (CV159) on hepatic ischemia/reperfusion injury in rats: evaluation with selective NO/pO2 electrodes and an electron paramagnetic resonance spin-trapping method.
Topics: Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Electrodes; Electron Spin Resonance Spectroscopy; Endothelium; Free Radical Scavengers; HMGB1 Protein; Hydroxyl Radical; Liver; Male; Mitochondria; Necrosis; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
CV-159, a unique dihydropyridine derivative, prevents TNF-induced inflammatory responses in human umbilical vein endothelial cells.
Topics: Atherosclerosis; Calcium Channel Blockers; Cells, Cultured; Depression, Chemical; Dihydropyridines; E-Selectin; Endothelial Cells; Female; Humans; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Umbilical Veins | 2010 |
Mechanisms underlying the anti-inflammatory effects of the Ca2+/calmodulin antagonist CV-159 in cultured vascular smooth muscle cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cardiovascular Diseases; Cells, Cultured; Dihydropyridines; Down-Regulation; Male; Muscle, Smooth, Vascular; NF-kappa B; Osmolar Concentration; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2010 |