curvularin has been researched along with zearalenone in 29 studies
| Studies (curvularin) | Trials (curvularin) | Recent Studies (post-2010) (curvularin) | Studies (zearalenone) | Trials (zearalenone) | Recent Studies (post-2010) (zearalenone) |
|---|---|---|---|---|---|
| 32 | 0 | 15 | 2,356 | 41 | 1,352 |
| Protein | Taxonomy | curvularin (IC50) | zearalenone (IC50) |
|---|---|---|---|
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | 2.402 | |
| PTK2B protein tyrosine kinase 2 beta | Homo sapiens (human) | 6.922 | |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | 2.402 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.34) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 12 (41.38) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Betina, V; Horáková, K | 1 |
| Ciegler, A; Fennell, D; Tjarks, LW; Vesonder, RF | 1 |
| Itoh, TJ; Kobayashi, A; Sato, H | 1 |
| Kajiyama, S; Kobayashi, A | 1 |
| Anke, T; Erkel, G; Förstermann, U; Hausding, M; Kleinert, H; Yao, Y | 1 |
| Castanet, AS; Fürstner, A; Lehmann, CW; Radkowski, K | 1 |
| Fujioka, S; Kawano, T; Kimura, Y; Kusano, M; Nakagami, K; Shimada, A | 1 |
| Gunatilaka, AA; Pierson, EE; Pierson, LS; Seliga, CJ; Vanetten, HD; Wijeratne, EM; Zhan, J; Zhang, J | 1 |
| Gunatilaka, AA; Zhan, J | 1 |
| Kuwahara, S; Miyagi, T | 1 |
| Liang, Q; Pan, X; She, X; Sun, Y; Yu, B | 1 |
| Anke, T; Elzner, S; Erkel, G; Förstermann, U; Kleinert, H; Kunz, H; Schmidt, D; Schollmeyer, D | 1 |
| Andersen, B; Hollensted, M | 1 |
| Chen, MJ; Dai, SK; Li, X; Ouyang, YC; Sun, HM; Wang, GH; Xie, LW; Zou, K | 1 |
| Art, J; Erkel, G; Goldring, MB; Jung, M; Kleinert, H; Pautz, A; Rauschkolb, P; Schmidt, N | 1 |
| Stoltz, BM; Tadross, PM; Virgil, SC | 1 |
| Art, J; Erkel, G; Forsch, I; Horke, S; Jung, M; Kleinert, H; Pautz, A; Schmidt, N; Werner, A | 1 |
| Erkel, G; Rudolph, K; Serwe, A | 1 |
| Huang, CG; Li, CS; Li, XM; Lv, CT; Meng, LH; Wang, BG; Xu, GM | 1 |
| Cai, L; Chen, X; Ding, Z; Dong, J; Fang, H; Zhao, L | 1 |
| Anjum, K; Huang, H; Lian, XY; Song, T; Wang, W; Ye, X; Yu, S; Zhang, Z | 1 |
| Deng, A; Deng, Z; Gong, D; Guo, Z; Luo, D; Peng, Y; Zou, K | 1 |
| Andersen, RJ; Berlinck, RG; Costa, BZ; de Castro, MV; de Jesus, K; Ferreira, AG; Ferreira, ÉL; Gonçalves, NS; Ióca, LP; Mizuno, CM; Patrick, BO; Pereira Filho, ER; Santos, MF; Santos, RA; Seleghim, MH; Sette, LD; Williams, DE | 1 |
| Ha, TM; Kim, YC; Ko, W; Lee, SJ; Oh, H; Sohn, JH; Son, JY; Yim, JH | 1 |
| Cox, R; Schor, R | 1 |
| Allu, SR; Banne, S; Guo, J; He, Y; Jiang, J; Qi, N | 1 |
| Bi, Y; Deng, ZS; Guo, J; Li, X; Liu, YX; Pan, LR; Tan, Y; Yu, XJ; Zhao, Q; Zhong, J | 1 |
| Cheng, KW; Chou, TF; Li, S; Zhang, G | 1 |
| Deng, Z; Guo, Z; Yu, X; Zhou, F; Zhou, Y | 1 |
4 review(s) available for curvularin and zearalenone
| Article | Year |
|---|---|
[Molecular basis of probes for cytoskeletal proteins].
Topics: Animals; Bibenzyls; Colchicine; Cytoskeletal Proteins; Fertilization; Microtubules; Mitosis; Paclitaxel; Sea Urchins; Stilbenes; Zearalenone | 1993 |
Classic fungal natural products in the genomic age: the molecular legacy of Harold Raistrick.
Topics: Benzofurans; Biological Products; Citrinin; Emodin; Fungi; Griseofulvin; History, 20th Century; Humans; Lactones; Mycophenolic Acid; Zearalenone | 2018 |
AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors.
Topics: ATPases Associated with Diverse Cellular Activities; Binding Sites; Carbazoles; Humans; Molecular Dynamics Simulation; Neoplasms; Pyrazoles; Pyrimidines; Quinazolines; Small Molecule Libraries; Zearalenone | 2021 |
Review of 10,11-Dehydrocurvularin: Synthesis, Structural Diversity, Bioactivities and Mechanisms.
Topics: Fungi; Lactones; Macrolides; Zearalenone | 2022 |
25 other study(ies) available for curvularin and zearalenone
| Article | Year |
|---|---|
Cytotoxic activity of macrocyclic metabolites from fungi.
Topics: Cell Division; Cell Survival; Cyclopentanes; Cytochalasins; HeLa Cells; Mycotoxins; Structure-Activity Relationship; Zearalenone | 1977 |
Curvularin from penicillium baradicum Baghdadi NRRL 3754, and biological effects.
Topics: Animals; Embryo, Mammalian; Estrogens, Non-Steroidal; Female; Penicillium; Resorcinols; Swine; Zearalenone | 1976 |
[Functional and distributional changes of MTOC's in centrosomes induced by antimitotic agents].
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Deuterium; Fluorescent Antibody Technique; Male; Microscopy, Electron; Spermatozoa; Spindle Apparatus; Zearalenone | 1989 |
Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungi.
Topics: Cell Division; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; Epoxy Compounds; Gene Expression Regulation; Humans; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Penicillium; Promoter Regions, Genetic; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Zearalenone | 2003 |
Total synthesis of (s)-(+)-citreofuran by ring closing alkyne metathesis.
Topics: Alkynes; Alternaria; Ascomycota; Catalysis; Crystallography, X-Ray; Cyclization; DNA Damage; Furans; Indicators and Reagents; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Penicillium; Stereoisomerism; Zearalenone | 2003 |
Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp.
Topics: Animals; Antinematodal Agents; Aspergillus; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Molecular Structure; Plant Diseases; Plant Roots; Seedlings; Spectrum Analysis; Tylenchoidea; Zearalenone | 2003 |
A new anthraquinone and cytotoxic curvularins of a Penicillium sp. from the rhizosphere of Fallugia paradoxa of the Sonoran desert.
Topics: Anthraquinones; Antibiotics, Antineoplastic; Cell Line, Tumor; Desert Climate; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Penicillium; Plant Roots; Rosaceae; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Zearalenone | 2004 |
Microbial transformation of curvularin.
Topics: Biotransformation; Drug Screening Assays, Antitumor; Fungi; Glucosides; Glycosyltransferases; Methyltransferases; Mixed Function Oxygenases; Molecular Structure; Tumor Cells, Cultured; Zearalenone | 2005 |
A concise synthetic approach to beta,gamma-dehydrocurvularin: synthesis of (+/-)-di-O-methyl-beta,gamma-dehydrocurvularin.
Topics: Antinematodal Agents; Carboxylic Acids; Cyclization; Esterification; Macrolides; Microwaves; Zearalenone | 2007 |
First total syntheses and spectral data corrections of 11-alpha-methoxycurvularin and 11-beta-methoxycurvularin.
Topics: Molecular Structure; Stereoisomerism; Zearalenone | 2007 |
Inhibitors of inducible NO synthase expression: total synthesis of (S)-curvularin and its ring homologues.
Topics: Cell Line; Crystallography, X-Ray; Cyclization; Drug Evaluation, Preclinical; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Lactones; Models, Molecular; Molecular Structure; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Stereoisomerism; Zearalenone | 2008 |
Metabolite production by different Ulocladium species.
Topics: Alternaria; Chromatography, High Pressure Liquid; Food Microbiology; Multivariate Analysis; Mycological Typing Techniques; Mycotoxins; Perylene; Phylogeny; Species Specificity; Zearalenone | 2008 |
Isolation and difference in anti-Staphylococcus aureus bioactivity of curvularin derivates from fungus Eupenicillium sp.
Topics: Anti-Bacterial Agents; Apoptosis; Eupenicillium; Species Specificity; Staphylococcus aureus; Zearalenone | 2009 |
Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes.
Topics: Anti-Inflammatory Agents; Cartilage, Articular; Cell Line, Transformed; Chondrocytes; Cytokines; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Interferon-Stimulated Gene Factor 3; Janus Kinase 2; NF-kappa B p50 Subunit; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Receptors, Glucocorticoid; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; Trans-Activators; Zearalenone | 2010 |
Aryne acyl-alkylation in the general and convergent synthesis of benzannulated macrolactone natural products: an enantioselective synthesis of (-)-curvularin.
Topics: Alkylation; Biological Factors; Macromolecular Substances; Molecular Structure; Stereoisomerism; Zearalenone | 2010 |
The anti-inflammatory fungal compound (S)-curvularin reduces proinflammatory gene expression in an in vivo model of rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Line, Transformed; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Mice; Mice, Inbred DBA; Mice, Transgenic; Zearalenone | 2012 |
Inhibition of TGF-β signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Genes, Reporter; Hep G2 Cells; Humans; Lactones; Macrocyclic Compounds; Neovascularization, Physiologic; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Zearalenone | 2013 |
Sulfur-containing cytotoxic curvularin macrolides from Penicillium sumatrense MA-92, a fungus obtained from the rhizosphere of the mangrove Lumnitzera racemosa.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Combretaceae; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Macrolides; Molecular Conformation; Molecular Structure; Penicillium; Structure-Activity Relationship; Sulfur; Zearalenone | 2013 |
Antioxidant activities and phenolics of fermented Bletilla formosana with eight plant pathogen fungi.
Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Fermentation; Helminthosporium; Orchidaceae; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Plant Tubers; Sulfonic Acids; Zearalenone | 2014 |
A new curvularin glycoside and its cytotoxic and antibacterial analogues from marine actinomycete Pseudonocardia sp. HS7.
Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Cell Line, Tumor; Glycosides; Holothuria; Humans; Inhibitory Concentration 50; Macrolides; Molecular Structure; Stereoisomerism; Zearalenone | 2016 |
Biotransformation of (-)-(10E,15S)-10,11-Dehydrocurvularin.
Topics: Biotransformation; Diterpene Alkaloids; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Polyporales; Zearalenone | 2015 |
Condensation of Macrocyclic Polyketides Produced by Penicillium sp. DRF2 with Mercaptopyruvate Represents a New Fungal Detoxification Pathway.
Topics: Crystallography, X-Ray; Cysteine; Drug Screening Assays, Antitumor; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Penicillium; Polyketides; Stereoisomerism; Zearalenone | 2016 |
Anti-Inflammatory Effects of Curvularin-Type Metabolites from a Marine-Derived Fungal Strain Penicillium sp. SF-5859 in Lipopolysaccharide-Induced RAW264.7 Macrophages.
Topics: Animals; Anti-Inflammatory Agents; Aquatic Organisms; Dinoprostone; Inhibitory Concentration 50; Macrophages; Mice; Nitric Oxide Synthase Type II; Penicillium; RAW 264.7 Cells; Zearalenone | 2017 |
A Unified Synthetic Approach to Optically Pure Curvularin-Type Metabolites.
Topics: Molecular Structure; Optical Phenomena; Zearalenone | 2019 |
10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred BALB C; Mice, Nude; STAT3 Transcription Factor; Xenograft Model Antitumor Assays; Zearalenone | 2021 |