curcumin and methyl-linoleate

curcumin has been researched along with methyl-linoleate* in 1 studies

Other Studies

1 other study(ies) available for curcumin and methyl-linoleate

ArticleYear
Feruloylacetone as the model compound of half-curcumin: synthesis and antioxidant properties.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:4

    In order to clarify the contribution of phenolic and enolic hydroxyl group to the antioxidant capacity of feruloylacetone, a model compound of half-curcumin, 6-(p-hydroxy-m-methoxyphenyl)-5-hexene-2,4-dione (FT), 6-(p-benzyloxy-m-methoxyphenyl)-5-hexene-2,4-dione (BMFT), 6-(m,p-dihydroxyphenyl)-5-hexene-2,4-dione (DDFT), 6-(p-hydroxy-m-methoxyphenyl)hexane-2,4-dione (DHFT), 6-(p-hydroxy-m-methoxyphenyl)-5-hexene-2,4-diol (THFT), and ethyl 2-(p-hydroxy-m-methoxybenzylidene)-3-oxobutanoate (EOFT) were synthesized. The radical-scavenging abilities of these compounds were tested by trapping 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical (ABTS(+ยท)), 2,2'-diphenyl-1-picrylhydrazyl (DPPH), and galvinoxyl radicals. The reductive capacities were screened by quenching singlet oxygen and by inhibiting the oxidation of linoleic acid. They were also employed to inhibit the oxidation of DNA mediated by hydroxyl radical and 2,2'-azobis(2-amidinopropane hydrochloride) (AAPH). In addition, they were applied to protect erythrocytes against AAPH- and hemin-induced hemolysis. The obtained results revealed that the antioxidant capacity of half-curcumin was derived from the phenolic-OH and the conjugated linkage between phenolic and enolic-OH. The enolic-OH itself cannot trap radicals.

    Topics: Acetone; Amidines; beta Carotene; Copper; Curcumin; DNA; Erythrocytes; Free Radical Scavengers; Free Radicals; Glutathione; Hemin; Hemolysis; Humans; Linoleic Acids; Oxidation-Reduction; Structure-Activity Relationship; Styrenes

2011