curcumin and methacryloyl-chloride

curcumin has been researched along with methacryloyl-chloride* in 1 studies

Other Studies

1 other study(ies) available for curcumin and methacryloyl-chloride

Article	Year
Synthesis, characterization and fluorescent properties of water-soluble glycopolymer bearing curcumin pendant residues. Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:8 Curcumin is a potential natural anticancer drug with low oral bioavailability because of poor water solubility. The aqueous solubility of curcumin is enhanced by means of modification with the carbohydrate units. Polymerization of the curcumin-containing monomer with carbohydrate-containing monomer gives the water-soluble glycopolymer bearing curcumin pendant residues. The obtained copolymers (P1 and P2) having desirable water solubility were well-characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), UV-Vis absorption spectroscopy, and photoluminescence spectroscopy. The copolymer P2 with a molar ratio of 1:6 (curcumin/carbohydrate) calculated from the proton NMR results exhibits a similar anticancer activity compared to original curcumin, which may serve as a potential chemotherapeutic agent in the field of anticancer medicine. Topics: Antineoplastic Agents; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Enzymes, Immobilized; Fungal Proteins; HeLa Cells; Humans; Lipase; Methacrylates; Methylamines; Methylglucosides; Polymerization; Solubility; Solutions; Water	2016

Article

Year

Synthesis, characterization and fluorescent properties of water-soluble glycopolymer bearing curcumin pendant residues.

Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:8

Curcumin is a potential natural anticancer drug with low oral bioavailability because of poor water solubility. The aqueous solubility of curcumin is enhanced by means of modification with the carbohydrate units. Polymerization of the curcumin-containing monomer with carbohydrate-containing monomer gives the water-soluble glycopolymer bearing curcumin pendant residues. The obtained copolymers (P1 and P2) having desirable water solubility were well-characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), UV-Vis absorption spectroscopy, and photoluminescence spectroscopy. The copolymer P2 with a molar ratio of 1:6 (curcumin/carbohydrate) calculated from the proton NMR results exhibits a similar anticancer activity compared to original curcumin, which may serve as a potential chemotherapeutic agent in the field of anticancer medicine.

Topics: Antineoplastic Agents; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Enzymes, Immobilized; Fungal Proteins; HeLa Cells; Humans; Lipase; Methacrylates; Methylamines; Methylglucosides; Polymerization; Solubility; Solutions; Water

2016