curcumin has been researched along with indirubin* in 2 studies
1 review(s) available for curcumin and indirubin
| Article | Year |
|---|---|
Nutritional support for chronic myelogenous and other leukemias: a review of the scientific literature.
Chronic myelogenous leukemia (CML) is a slowly progressive disease characterized by the overproduction of granulocytes (neutrophils, eosinophils, and basophils). A blood smear shows moderate elevations in white blood cell counts that may persist for years and be benign. Platelets are increased in number, although their function is impaired, resulting in symptoms of easy bleeding (purpura, swollen gums). Conventional medical treatment is a marrow transplant and alkylating agents, which are usually prescribed only during crisis. Several nutrients and botanicals have been studied for use in CML, including vitamin A and all-trans retinoic acid (Retin-A), vitamin D3, vitamin E, vitamin B12, indirubin (found in herbs including Indigofera tinctoria and Isatis tinctoria), and Curcuma longa. This article briefly reviews the scientific literature on the therapeutic use of these nutrients for CML. Topics: Antineoplastic Agents; Curcumin; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nutritional Support; Tretinoin; Vitamins | 2002 |
1 other study(ies) available for curcumin and indirubin
| Article | Year |
|---|---|
[Study on active constituents of traditional Chinese medicine reversing multidrug resistance of tumor cells in vitro].
To screen drugs reversing multidrug resistance of tumor cells from active constituents of traditional Chinese medicine and to study the reversal action.. The kill effects of the drugs on tumor cell lines in vitro were determined with MTT method. The Jin's formula was used to analyse the effect of drug combination.. 5 micrograms/ml rhynchophylline, 2 micrograms/ml jatrorrhizine and 1.25 micrograms/ml indirulin could reverse multidrug resistance for vincristine on KBv200 cell line by 16.8, 5.1 and 4 fold respectively. 1.56-12.5 micrograms/ml curcumine combining with vincristine could sensitize antitumor effect both on KB and KBv200 cell lines.. All rhynchophylline, jatrorrhizine and indirulin could reverse multidrug resistance for vincristine on KBv200 cell line. Curcumine combinating vincristine could sensitize antitumor effect both on kB and kBv200 cell lines. Topics: Antineoplastic Agents, Phytogenic; Berberine; Curcumin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Indoles; Tumor Cells, Cultured; Vincristine | 2001 |