curcumin has been researched along with dazomet* in 1 studies
1 other study(ies) available for curcumin and dazomet
| Article | Year |
|---|---|
Design and synthesis of novel iminothiazinylbutadienols and divinylpyrimidinethiones as ARE inducers.
Novel iminothiazinylbutadienols and divinylpyrimidinethiones were designed and synthesized as analogues of curcumin with its diketone moiety masked as a heterocyclic adduct with thiourea. The chemical stability of these novel heterocyclic compounds was improved as compared to curcumin. They exhibit longer half-lives and do not react with nucleophilic thiols under physiological conditions. In an ARE-luciferase reporter assay, some of these new curcumin analogues are more effective ARE activators than curcumin and isothiocyanates. Topics: Antioxidant Response Elements; Curcumin; Drug Design; Isothiocyanates; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Sulfoxides; Thiadiazines; Thiones; Thiourea | 2014 |