curcumin has been researched along with boron-nitride* in 2 studies
2 other study(ies) available for curcumin and boron-nitride
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In vitro investigation of the effects of boron nitride nanotubes and curcumin on DNA damage.
Stem cells provide an opportunity to analyse the effects of xenobiotic on cell viability, differentiation and cell functions. Evaluation of the possible cytotoxic and DNA damaging effects on bone marrow CD34. In this study, it was aimed to evaluate the cytotoxic and DNA damaging effects of boron nitride nanotubes which are commonly used in pyroelectric, piezoelectric and optical applications, but there is not enough information about its biocompatibility. Also, it was intended to research the effects of curcumin being used frequently in treatment processes for antioxidant properties.. The possible cytotoxic and DNA damaging effects of boron nitride nanotubes and curcumin on CD34. Boron nitride nanotubes and curcumin had cytotoxic effects and cause DNA damage on CD34 Topics: Animals; Antigens, CD34; Boron Compounds; Cell Line; Cell Survival; Cricetulus; Curcumin; DNA Damage; HeLa Cells; Humans; Mesenchymal Stem Cells; Nanotubes; Reactive Oxygen Species | 2019 |
Boron nitride nanotubes as vehicles for intracellular delivery of fluorescent drugs and probes.
To evaluate the response of cells to boron nitride nanotubes (BNNTs) carrying fluorescent probes or drugs in their inner channel by assessment of the cellular localization of the fluorescent cargo, evaluation of the in vitro release and biological activity of a drug (curcumin) loaded in BNNTs.. Cells treated with curcumin-loaded BNNTs and stimulated with lipopolysaccharide were assessed for nitric oxide release and stimulation of IL-6 and TNF-α. The cellular trafficking of two cell-permeant dyes and a non-cell-permeant dye loaded within BNNTs was imaged.. BNNTs loaded with up to 13 wt% fluorophores were internalized by cells and controlled release of curcumin triggered cellular pathways associated with the known anti-inflammatory effects of the drug.. The overall findings indicate that BNNTs can function as nanocarriers of biologically relevant probes/drugs allowing one to examine/control their local intracellular localization and biochemical effects, leading the way to applications as intracellular nanosensors. Topics: Boron Compounds; Curcumin; Drug Carriers; Drug Delivery Systems; Fluorescence; Humans; Inflammation; Interleukin-6; Nanotubes; Nitric Oxide; Tumor Necrosis Factor-alpha | 2016 |