curcumin and bisacurone

curcumin has been researched along with bisacurone* in 8 studies

Reviews

1 review(s) available for curcumin and bisacurone

ArticleYear
Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:9

    Turmeric, a dried powder derived from the rhizome of Curcuma longa, has been used for centuries in certain parts of the world and has been linked to numerous biological activities including antioxidant, anti-inflammatory, anticancer, antigrowth, anti-arthritic, anti-atherosclerotic, antidepressant, anti-aging, antidiabetic, antimicrobial, wound healing, and memory-enhancing activities. One component of turmeric is curcumin, which has been extensively studied, as indicated by more than 5600 citations, most of which have appeared within the past decade. Recent research has identified numerous chemical entities from turmeric other than curcumin. It is unclear whether all of the activities ascribed to turmeric are due to curcumin or whether other compounds in turmeric can manifest these activities uniquely, additively, or synergistically with curcumin. However, studies have indicated that turmeric oil, present in turmeric, can enhance the bioavailability of curcumin. Studies over the past decade have indicated that curcumin-free turmeric (CFT) components possess numerous biological activities including anti-inflammatory, anticancer, and antidiabetic activities. Elemene derived from turmeric is approved in China for the treatment of cancer. The current review focuses on the anticancer and anti-inflammatory activities exhibited by CFT and by some individual components of turmeric, including turmerin, turmerone, elemene, furanodiene, curdione, bisacurone, cyclocurcumin, calebin A, and germacrone.

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Clinical Trials as Topic; Curcuma; Curcumin; Cyclohexanols; Disease Models, Animal; Furans; Heterocyclic Compounds, 2-Ring; Humans; Hypoglycemic Agents; Inflammation; Neoplasms; Sesquiterpenes; Sesquiterpenes, Germacrane

2013

Other Studies

7 other study(ies) available for curcumin and bisacurone

ArticleYear
Hypolipidemic and Anti-Inflammatory Effects of
    International journal of molecular sciences, 2023, May-27, Volume: 24, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Curcuma; Cytokines; Diet, High-Fat; Interleukin-6; Ligands; Lipopolysaccharides; Mice; NF-kappa B; Tumor Necrosis Factor-alpha

2023
Quantification of Bisacurone and Curcuminoids in Turmeric Products by Liquid Chromatography Coupled with Tandem Mass Spectrometry.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:2

    Turmeric products have many useful physiological functions and are widely used as health food and food ingredient. Here, we report the use of HPLC-ESI-MS/MS to simultaneously quantify bisacurone and three curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin) in turmeric products (high viscosity liquid, granular powder, tablet, and solution). The results showed that the standard values and measured values of curcumin in each product were almost same. Demethoxycurcumin and bisdemethoxycurcumin were contained in each products. Meanwhile, the content of bisacurone differed greatly among the products. In particular, the highest amount of bisacurone was found in the turmeric product A (high viscosity liquid, 9.48 g/100 g product). It would become important to consider the bisacurone content in turmeric products.

    Topics: Chromatography, Liquid; Curcuma; Curcumin; Cyclohexanols; Diarylheptanoids; Sesquiterpenes; Tandem Mass Spectrometry

2022
[Quantitative Analysis of Bisacurone in Turmeric by HPLC Using Relative Molar Sensitivity].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2022, Volume: 63, Issue:6

    A novel method was developed for quantification of bisacuron (BC) and dehydrozingerone (DZ), the functional component of turmeric (Curcuma longa.L)-containing foods, using a relative molar sensitivity (RMS) method based on the combination of HPLC-UV and

    Topics: Chromatography, High Pressure Liquid; Curcuma; Cyclohexanols; Sesquiterpenes

2022
Two pairs of bisabolane sesquiterpenoid stereoisomers, bisacurone D-G, from the rhizome of Curcuma longa L.
    Fitoterapia, 2020, Volume: 146

    Phytochemical investigation of an extract of the rhizome of Curcuma longa L., resulted in the identification of four undescribed bisabolane sesquiterpenoids, namely as bisacurone D-G (1-4). With the aid of comprehensive spectroscopic techniques (NMR, IR, UV, MS), the structures of all isolated compounds were elucidated and subsequently screened for both anti-inflammatory and cytotoxic biological activities, Compounds 1 and 2 showed moderate inhibitory activity toward LPS-induced NO production on RAW 264.7 macrophages.

    Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; China; Curcuma; Cyclohexanols; Humans; Mice; Molecular Structure; Monocyclic Sesquiterpenes; Nitric Oxide; Phytochemicals; Plant Extracts; RAW 264.7 Cells; Rhizome; Sesquiterpenes

2020
Choleretic Activity of Turmeric and its Active Ingredients.
    Journal of food science, 2016, Volume: 81, Issue:7

    Turmeric, a rhizome of Curcumin longa L. is widely used as both a spice and an herbal medicine. The traditional use of turmeric in gastroenterology is mainly based on its choleretic activity. The aim of this study is to determine the effects of turmeric on bile flow (BF) and total bile acids (TBAs) excretion in a bile fistula rat model after acute duodenal administration. A significant dose-dependent enhancement in both BF and TBAs was detected after treatment with the turmeric decoctions which suggested the choleretic activity was bile acid-dependent secretion. In order to direct the active group of compounds, aqueous (AE), ethyl acetate (EtOAc), and petroleum ether (PE) extracts were investigated. The EtOAc and PE extracts showing high effects were purified to locate the active ingredients. Three curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin) and 2 sesquiterpenes (bisacurone B and ar-turmerone) were isolated. It was found Bisacurone B was the most potent choleretic ingredient followed by ar-turmerone, bisdemethoxycurcumin demethoxycurcumin, and then curcumin. The amounts of the active ingredients were quantitatively analyzed by high-performance liquid chromatography. The EtOAc and PE extracts had high sesquiterpenes and curcuminoids content, while the AE extract had poor content of sesquiterpenes and curcuminoids which affected neither BF nor TBAs. Based on the results of multiple linear regression analysis, the content of BIS and TUR were dominant factors (P < 0.01) of controlling BL and TBAs in EtOAC and PE extracts.

    Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Chromatography, High Pressure Liquid; Curcuma; Curcumin; Cyclohexanols; Diarylheptanoids; Ketones; Plant Extracts; Rats; Rhizome; Sesquiterpenes

2016
Three novel terpenoids from the rhizomes of Curcuma longa.
    Journal of Asian natural products research, 2009, Volume: 11, Issue:6

    Investigation of the EtOH extract of the rhizomes of Curcuma longa led to the isolation of two new sesquiterpenes, 2-methoxy-5-hydroxybisabola-3,10-diene-9-one (1) and 2,8-epoxy-5-hydroxybisabola-3,10-diene-9-one (2), one new monoterpene, 2-(2,5-dihydroxy-4-methylcyclohex-3-enyl)propanoic acid (3), together with five known sesquiterpenes (4-8). Among the known compounds, bisacurone A (5) and 4-methylene-5-hydroxybisabola-2,10-diene-9-one (6) were isolated from C. longa and genus Curcuma for the first time, respectively. Their structures were established on the basis of various spectroscopic analyses including HR-ESI-MS, 1D and 2D NMR, IR spectra, and by comparison of their spectral data with those of related compounds.

    Topics: Curcuma; Cyclohexanols; Drugs, Chinese Herbal; Molecular Structure; Monoterpenes; Nuclear Magnetic Resonance, Biomolecular; Rhizome; Sesquiterpenes

2009
Alkaloid and sesquiterpenes from the root tuber of Curcuma longa.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:7

    One new quinoline alkaloid and seven known bisabolane sesquiterpenes: 2-(2'-methyl-1'-propenyl)-4, 6-dimethyl-7-hydroxyquinoline (1), 2, 5-dihydroxybisabola-3, 10-diene (2), 4, 5-dihydroxybisabola-2,10-diene (3), turmeronol A (4), bisacurone (5), bisacurone A (6), bisacurone B (7) , bisacurone C (8), as well as dehydrozingerone (9) and zingerone (10) were isolated from the root tuber of Curcuma longa. Their structures were identified by spectral evidence. Compound 1 is a new compound, compounds 6 -8 were isolated from this plant for the first time and compounds 9 - 10 from Curcuma for the first time.

    Topics: Alkaloids; Curcuma; Cyclohexanols; Guaiacol; Molecular Structure; Plant Tubers; Plants, Medicinal; Sesquiterpenes; Styrenes

2008