curcumin and bis(2-ethylhexyl)-2-3-4-5-tetrabromophthalate

Bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) has been used as a replacement in some commercial flame-retardant mixtures. It is widely used in industrial products, so the probability of human exposure to TBPH is high. Yet, little is known about how it is metabolized or its toxicity. To this end, we investigated what effect oral exposure of Balb/c mice to TBPH at concentrations of 200 mg kg

Topics: Animals; Chemical and Drug Induced Liver Injury; Curcumin; Dose-Response Relationship, Drug; Environmental Exposure; Flame Retardants; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Phthalic Acids; Random Allocation