curcumin has been researched along with 4-cresol-sulfate* in 1 studies
1 trial(s) available for curcumin and 4-cresol-sulfate
| Article | Year |
|---|---|
Can curcumin supplementation reduce plasma levels of gut-derived uremic toxins in hemodialysis patients? A pilot randomized, double-blind, controlled study.
Gut dysbiosis is common in patients with chronic kidney disease (CKD) and is closely related to inflammatory processes. Some nutritional strategies, such as bioactive compounds present in curcumin, have been proposed as an option to modulate the gut microbiota and decrease the production of uremic toxins such as indoxyl sulfate (IS), p-cresyl sulfate (pCS) and indole-3 acetic acid (IAA).. To evaluate the effects of curcumin supplementation on uremic toxins plasma levels produced by gut microbiota in patients with CKD on hemodialysis (HD).. The oral supplementation of curcumin for three months seems to reduce p-CS plasma levels in HD patients, suggesting a gut microbiota modulation. Topics: Adult; Aged; Cresols; Curcumin; Dietary Supplements; Double-Blind Method; Female; Gastrointestinal Microbiome; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Pilot Projects; Renal Dialysis; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2021 |