curcumin and 2-oxindole

curcumin has been researched along with 2-oxindole* in 2 studies

Other Studies

2 other study(ies) available for curcumin and 2-oxindole

Article	Year
Synthesis of Bis-pyrrolizidine-Fused Dispiro-oxindole Analogues of Curcumin via One-Pot Azomethine Ylide Cycloaddition: Experimental and Computational Approach toward Regio- and Diastereoselection. Organic letters, 2015, Sep-18, Volume: 17, Issue:18 Curcumin has been transformed to racemic curcuminoids via an azomethine ylide cycloaddition reaction using isatin/acenaphthoquinone and proline as the reagents. The products were characterized by extensive 1D/2D NMR analysis and single-crystal X-ray crystallographic studies. The enantiomers of one racemic product were separated by HPLC on a Chiralcel OD-H column and were indeed confirmed by the CD spectra of the separated enantiomers. Topics: Azo Compounds; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Curcumin; Cycloaddition Reaction; Indoles; Isatin; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxindoles; Pyrrolizidine Alkaloids; Stereoisomerism; Thiosemicarbazones	2015
Efficient synthesis of multicyclic spirooxindoles via a cascade Michael/Michael/oxa-Michael reaction of curcumins and isatylidene malononitriles. Organic & biomolecular chemistry, 2012, Feb-28, Volume: 10, Issue:8 A cascade Michael/Michael/oxa-Michael reaction between curcumins and isatylidene malononitriles has been developed. Multicyclic spirooxindoles were prepared in excellent yields and diastereoselectivities. DMAP was found to catalyze this transformation efficiently under mild reaction conditions. Topics: Catalysis; Curcumin; Heterocyclic Compounds; Indoles; Models, Molecular; Molecular Structure; Nitriles; Oxindoles; Spiro Compounds	2012

Article

Year

Synthesis of Bis-pyrrolizidine-Fused Dispiro-oxindole Analogues of Curcumin via One-Pot Azomethine Ylide Cycloaddition: Experimental and Computational Approach toward Regio- and Diastereoselection.

Organic letters, 2015, Sep-18, Volume: 17, Issue:18

Curcumin has been transformed to racemic curcuminoids via an azomethine ylide cycloaddition reaction using isatin/acenaphthoquinone and proline as the reagents. The products were characterized by extensive 1D/2D NMR analysis and single-crystal X-ray crystallographic studies. The enantiomers of one racemic product were separated by HPLC on a Chiralcel OD-H column and were indeed confirmed by the CD spectra of the separated enantiomers.

Topics: Azo Compounds; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Curcumin; Cycloaddition Reaction; Indoles; Isatin; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxindoles; Pyrrolizidine Alkaloids; Stereoisomerism; Thiosemicarbazones

2015

Efficient synthesis of multicyclic spirooxindoles via a cascade Michael/Michael/oxa-Michael reaction of curcumins and isatylidene malononitriles.

Organic & biomolecular chemistry, 2012, Feb-28, Volume: 10, Issue:8

A cascade Michael/Michael/oxa-Michael reaction between curcumins and isatylidene malononitriles has been developed. Multicyclic spirooxindoles were prepared in excellent yields and diastereoselectivities. DMAP was found to catalyze this transformation efficiently under mild reaction conditions.

Topics: Catalysis; Curcumin; Heterocyclic Compounds; Indoles; Models, Molecular; Molecular Structure; Nitriles; Oxindoles; Spiro Compounds

2012