cucurbitacins has been researched along with estrone in 2 studies
| Studies (cucurbitacins) | Trials (cucurbitacins) | Recent Studies (post-2010) (cucurbitacins) | Studies (estrone) | Trials (estrone) | Recent Studies (post-2010) (estrone) |
|---|---|---|---|---|---|
| 184 | 2 | 114 | 10,266 | 432 | 1,372 |
| Protein | Taxonomy | cucurbitacins (IC50) | estrone (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.1261 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 6.589 | |
| 17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | 0.4134 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.301 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.3743 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, MS; El-Senduny, F; Halaweish, FT; Taylor, J | 1 |
| Abd El Hameid, MK; Abou-Salim, MA; Elshaier, YAMM; Halaweish, F; Shaaban, MA | 1 |
2 other study(ies) available for cucurbitacins and estrone
| Article | Year |
|---|---|
Biological screening of cucurbitacin inspired estrone analogs targeting mitogen-activated protein kinase (MAPK) pathway.
Topics: Binding Sites; Cell Line, Tumor; Cell Survival; Cucurbitacins; Enzyme-Linked Immunosorbent Assay; Estrone; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Docking Simulation; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins B-raf | 2017 |
Design, synthesis and biological study of hybrid drug candidates of nitric oxide releasing cucurbitacin-inspired estrone analogs for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cucurbitacins; Drug Design; Drug Screening Assays, Antitumor; Estrone; G1 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Molecular Docking Simulation; Molecular Structure; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Nitric Oxide; Nitric Oxide Donors; Structure-Activity Relationship | 2019 |