Page last updated: 2024-09-03

cucurbitacins and cucurbitaceae

cucurbitacins has been researched along with cucurbitaceae in 32 studies

Compound Research Comparison

Studies (cucurbitacins)	Trials (cucurbitacins)	Recent Studies (post-2010) (cucurbitacins)	Studies (cucurbitaceae)	Trials (cucurbitaceae)	Recent Studies (post-2010) (cucurbitaceae)
184	2	114	1,649	15	1,073

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (25.00)	29.6817
2010's	14 (43.75)	24.3611
2020's	10 (31.25)	2.80

Authors

Authors	Studies
Attard, EG; Scicluna-Spiteri, A	1
Duckett, CN; Gillespie, JJ; Kjer, KM; Tallamy, DW	1
Bonucelli, M; Cerdá-Nicolás, M; Giner, RM; Máñez, S; Orsi, C; Prieto, M; Recio, MC; Ríos, JL	1
Ellmerer, EP; Mair, ME; Seger, C; Stuppner, H; Sturm, S	1
Hou, SX; Hu, P; Liu, HL; Wang, GS; Wang, L; Ye, LM; Zhang, JF	1
Hu, F; Kong, C; Liang, W; Yang, X; Zhang, M	1
Assunção, JC; Braz-Filho, R; Chaves, DC; Lemos, TL; Monte, FJ	1
Fu, HW; Pei, YH; Zheng, CH	1
Caro, MS; da Rosa Guimarães, T; Durán, FJ; Lang, KL; Palermo, JA; Rocha Machado, V; Schenkel, EP; Silva, IT; Simões, CM; Teixeira, MR; Zimmermann, LA	1
Godfrey, LD; Pedersen, AB	1
Cai, JY; He, XH; Ouyang, DY; Ren, S; Saltis, M; Xu, LH; Zha, QB	1
Chen, JJ; Geng, CA; Guo, RH; Huang, XY; Ma, YB; Wang, LJ; Zhang, Q; Zhang, RP; Zhang, XM	1
Campos Bernardes, LS; Deagosto, E; Duran, FJ; Lang, KL; Machado, VR; Palermo, J; Rossini, C; Schenkel, EP; Zimmermann, LA	1
Ho, CH; Ho, HH; Ho, MG; Ho, SP	1
Chen, GY; Chen, XB; Guo, DA; Hu, LH; Lei, M; Liu, JH; Liu, X; Meng, YH	1
Adler, LS; Barber, NA; Gillespie, SD; Hazzard, RV; Theis, N	1
Deng, ZP; Fan, HX; Xu, XT; Yao, QQ; Zhong, H	1
Ciprandi, G; De Lucia, A; Della Volpe, A; Mansi, N; Pastore, V; Varricchio, A; Varricchio, AM	1
Liu, HJ; Liu, Y; Shang, D; Su, Y; Wang, WD; Xiong, XZ; Xu, JJ	1
Aguiñiga-Sánchez, I; Aguirre-Medina, JF; Cadena-Iñiguez, J; Rivera-Martínez, AR; Ruiz-Posadas, LDM; Salazar-Aguilar, S; Santiago-Osorio, E; Soto-Hernández, M	1
Mazokopakis, EE	1
Hu, S; Jiang, HZ; Jiao, RH; Tan, R; Tan, RX	1
Adhikari, A; Ali, A; Aziz, N; Choudhary, MI; El-Seedi, HR; Kandel, RC; Khan, MN; Musharraf, SG; Shah, SMZ; Ul Haq, F; Ur-Rahman, A	1
Ras, R; Shahiduzzaman, M; Widmer, G	1
Arenas-Luna, VM; Hernández-Gutiérrez, S; Marcotullio, MC; Robles-Zepeda, RE; Torres-Moreno, H; Velazquez, C	1
Hernández-Gutiérrez, S; Robles-Zepeda, RE; Torres-Moreno, H; Velazquez, C; Vidal-Gutiérrez, M; Vilegas, W	1
Cadena-Iñiguez, J; Cadena-Zamudio, JD; Cortes-Cruz, M; Iñiguez-Luna, MI; Machida-Hirano, R; Morales-Flores, FJ; Soto-Hernández, RM; Watanabe, KN	1
de Villiers, A; Dziwornu, GA; Kaschula, CH; Mkwanazi, N; Sunassee, SN; Uushona, NE	1
Chen, H; Cheng, X; Huang, S; Li, D; Li, L; Liu, Y; Lucas, WJ; Ma, Y; Osbourn, A; Qin, Y; Shang, Y; Tian, S; Wang, X; Xun, W; Zhang, B; Zhang, Y; Zhao, G; Zhong, Y; Zhou, Y	1
Arenas-Luna, V; Hernández-Gutiérrez, S; Loredo-Mendoza, ML; Robles-Zepeda, RE; Tejeda-Dominguez, F; Torres-Moreno, H; Velazquez, C; Vidal-Gutiérrez, M; Vilegas, W	1
Boissot, N; Corre, MN; Lugan, R; Sadon, P	1
Almeida, A; Bak, S; Cárdenas, PD; Dong, L; Favero, BT; Lütken, H; Saenz-Mata, J	1

Reviews

1 review(s) available for cucurbitacins and cucurbitaceae

Article	Year
Bioprospecting of Sechium spp. varieties for the selection of characters with pharmacological activity. Scientific reports, 2021, 03-17, Volume: 11, Issue:1 Topics: Animals; Bioprospecting; Cell Line; Cucurbitaceae; Cucurbitacins; Fruit; Genotype; Humans; Mice; Plant Extracts; Polymorphism, Genetic	2021

Trials

1 trial(s) available for cucurbitacins and cucurbitaceae

Article	Year
Sinuclean Nebules treatment in children suffering from otitis media with effusion. International journal of pediatric otorhinolaryngology, 2017, Volume: 94 Topics: Administration, Intranasal; Audiometry; Child; Child, Preschool; Cucurbitaceae; Cucurbitacins; Double-Blind Method; Female; Hearing Tests; Humans; Male; Nebulizers and Vaporizers; Otitis Media with Effusion; Plant Extracts; Therapeutic Irrigation	2017

Article

Year

Sinuclean Nebules treatment in children suffering from otitis media with effusion.

International journal of pediatric otorhinolaryngology, 2017, Volume: 94

Topics: Administration, Intranasal; Audiometry; Child; Child, Preschool; Cucurbitaceae; Cucurbitacins; Double-Blind Method; Female; Hearing Tests; Humans; Male; Nebulizers and Vaporizers; Otitis Media with Effusion; Plant Extracts; Therapeutic Irrigation

2017

Other Studies

30 other study(ies) available for cucurbitacins and cucurbitaceae

Article	Year
Ecballium elaterium: an in vitro source of cucurbitacins. Fitoterapia, 2001, Volume: 72, Issue:1 Topics: Cells, Cultured; Cucurbitaceae; Cucurbitacins; Humans; Plant Extracts; Plants, Medicinal; Triterpenes	2001
Convergent evolution of cucurbitacin feeding in spatially isolated rootworm taxa (Coleoptera: Chrysomelidae; Galerucinae, Luperini). Molecular phylogenetics and evolution, 2003, Volume: 29, Issue:1 Topics: Animals; Base Sequence; Coleoptera; Cucurbitaceae; Cucurbitacins; DNA, Mitochondrial; DNA, Ribosomal; Electron Transport Complex IV; Feeding Behavior; Models, Genetic; Phylogeny; RNA, Ribosomal, 28S; Triterpenes	2003
Anti-inflammatory activity of two cucurbitacins isolated from Cayaponia tayuya roots. Planta medica, 2004, Volume: 70, Issue:5 Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cucurbitaceae; Cucurbitacins; Dose-Response Relationship, Drug; Edema; Female; Leukocytes; Leukotriene B4; Mice; Pain; Phospholipases A; Phospholipases A2; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Triterpenes	2004
1H and 13C NMR signal assignment of cucurbitacin derivatives from Citrullus colocynthis (L.) Schrader and Ecballium elaterium L. (Cucurbitaceae). Magnetic resonance in chemistry : MRC, 2005, Volume: 43, Issue:6 Topics: Carbon Isotopes; Citrullus; Cucurbitaceae; Cucurbitacins; Magnetic Resonance Spectroscopy; Molecular Conformation; Protons; Reference Standards; Triterpenes	2005
[The preparation of the polylacticacid nanoparticles of cucurbitacin and their drug loading]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Chemical Precipitation; Cucurbitaceae; Cucurbitacins; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Lactic Acid; Microspheres; Nanotechnology; Particle Size; Plants, Medicinal; Polyesters; Polymers; Triterpenes	2005
[Relationships of Aulacophora beetles feeding behavior with cucurbitacin types in host crops]. Ying yong sheng tai xue bao = The journal of applied ecology, 2005, Volume: 16, Issue:7 Topics: Animals; Coleoptera; Cucurbitaceae; Cucurbitacins; Feeding Behavior; Host-Parasite Interactions; Triterpenes	2005
Cucurbitacins from Cayaponia racemosa: isolation and total assignment of 1H and 13C NMR spectra. Magnetic resonance in chemistry : MRC, 2007, Volume: 45, Issue:5 Topics: Carbon Isotopes; Cucurbitaceae; Cucurbitacins; Fruit; Magnetic Resonance Spectroscopy; Molecular Structure; Protons; Triterpenes	2007
A new cucurbitacin from Bolbostemma paniculatum Franguent. Journal of Asian natural products research, 2007, Volume: 9, Issue:2 Topics: Cucurbitaceae; Cucurbitacins; Molecular Structure; Triterpenes	2007
New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. Planta medica, 2011, Volume: 77, Issue:14 Topics: Brazil; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cucurbitaceae; Cucurbitacins; Humans; Medicine, Traditional; Molecular Structure; Plant Extracts; Plant Roots; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization	2011
Evaluation of cucurbitacin-based gustatory stimulant to facilitate cucumber beetle (Coleoptera: Chrysomelidae) management with foliar insecticides in melons. Journal of economic entomology, 2011, Volume: 104, Issue:4 Topics: Animals; Carbaryl; Coleoptera; Cucurbitaceae; Cucurbitacins; Drug Combinations; Insect Control; Insecticides; Macrolides; Pesticide Synergists	2011
Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation. Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:3 Topics: Actin Depolymerizing Factors; Actins; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cucurbitaceae; Cucurbitacins; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cytokinesis; Down-Regulation; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Male; Prostatic Neoplasms; Up-Regulation	2012
Synthesis of hemslecin A derivatives: a new class of hepatitis B virus inhibitors. Bioorganic & medicinal chemistry letters, 2013, Mar-01, Volume: 23, Issue:5 Topics: Antiviral Agents; Cucurbitaceae; Cucurbitacins; DNA, Viral; Hep G2 Cells; Hepatitis B virus; Humans; Structure-Activity Relationship	2013
Chemical modification produces species-specific changes in cucurbitacin antifeedant effect. Journal of agricultural and food chemistry, 2013, Jun-12, Volume: 61, Issue:23 Topics: Animals; Coleoptera; Cucurbitaceae; Cucurbitacins; Feeding Behavior; Lepidoptera; Molecular Structure; Plant Extracts; Species Specificity	2013
Bitter bottle gourd (Lagenaria siceraria) toxicity. The Journal of emergency medicine, 2014, Volume: 46, Issue:6 Topics: Aged; Cucurbitaceae; Cucurbitacins; Diarrhea; Fluid Therapy; Foodborne Diseases; Humans; Male; Middle Aged; Nausea; Proton Pump Inhibitors; United States; Vomiting	2014
Cytotoxic cucurbitane triterpenoids isolated from the rhizomes of Hemsleya amabilis. Fitoterapia, 2014, Volume: 94 Topics: Alkaloids; Cell Survival; Cucurbitaceae; Cucurbitacins; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Plants, Medicinal; Rhizome; Triterpenes	2014
Attracting mutualists and antagonists: plant trait variation explains the distribution of specialist floral herbivores and pollinators on crops and wild gourds. American journal of botany, 2014, Volume: 101, Issue:8 Topics: Animals; Coleoptera; Crops, Agricultural; Cucurbita; Cucurbitaceae; Cucurbitacins; Ecology; Flowers; Herbivory; Phenotype; Plant Diseases; Pollination; Sesquiterpenes; Symbiosis; Terpenes; Volatile Organic Compounds	2014
[Study on in vivo pharmacokinetics of cucurbitacin injection in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:11 Topics: Administration, Oral; Animals; Cucurbitaceae; Cucurbitacins; Drugs, Chinese Herbal; Male; Rats; Rats, Wistar	2014
ANTITUMOR AND APOPTOTIC EFFECTS OF CUCURBITACIN A IN A-549 LUNG CARCINOMA CELLS IS MEDIATED VIA G2/M CELL CYCLE ARREST AND M-TOR/PI3K/AKT SIGNALLING PATHWAY. African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017, Volume: 14, Issue:2 Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Cell Cycle Checkpoints; Cucurbitaceae; Cucurbitacins; Humans; Lung; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Phosphotransferases; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases	2017
Sechium edule (Jacq.) Swartz, a New Cultivar with Antiproliferative Potential in a Human Cervical Cancer HeLa Cell Line. Nutrients, 2017, Jul-25, Volume: 9, Issue:8 Topics: Antineoplastic Agents, Phytogenic; Apigenin; Cell Proliferation; Cucurbitaceae; Cucurbitacins; Female; Flavanones; Flavonoids; Fruit; HeLa Cells; Humans; Inhibitory Concentration 50; Phloretin; Phytochemicals; Plant Extracts; Quercetin; Rutin; Uterine Cervical Neoplasms	2017
Ecballium Elaterium for Gastrointestinal Cancer Asian Pacific journal of cancer prevention : APJCP, 2018, 03-27, Volume: 19, Issue:3 Topics: Cell Line; Cucurbitaceae; Cucurbitacins; Fruit; Gastrointestinal Neoplasms; Humans	2018
Neocucurbitacin D, a novel lactone-type norcucurbitacin as xanthine oxidase inhibitor from Natural product research, 2020, Volume: 34, Issue:12 Topics: Cucurbitaceae; Cucurbitacins; Enzyme Inhibitors; Glycosides; Humans; Inhibitory Concentration 50; Lactones; Molecular Conformation; Seeds; Triterpenes; Xanthine Oxidase	2020
Metabolite Profiling and Quantitation of Cucurbitacins in Cucurbitaceae Plants by Liquid Chromatography coupled to Tandem Mass Spectrometry. Scientific reports, 2019, 11-05, Volume: 9, Issue:1 Topics: Chromatography, High Pressure Liquid; Cucurbitaceae; Cucurbitacins; Molecular Structure; Plant Extracts; Tandem Mass Spectrometry	2019
Effect of Ginsenoside-Rh2 and Curcurbitacin-B on Cryptosporidium parvum in vitro. Experimental parasitology, 2020, Volume: 212 Topics: Animals; Cell Line; Coccidiostats; Cryptosporidium parvum; Cucurbitaceae; Cucurbitacins; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ginsenosides; Inhibitory Concentration 50; Mice; Panax; Paromomycin; Plant Extracts; Real-Time Polymerase Chain Reaction; Solvents; Triterpenes	2020
Cucurbitacin IIb from Ibervillea sonorae Induces Apoptosis and Cell Cycle Arrest via STAT3 Inhibition. Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cucurbitaceae; Cucurbitacins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Structure; STAT3 Transcription Factor; Structure-Activity Relationship; Tumor Cells, Cultured	2020
Antiproliferative activity of standardized phytopreparations from Ibervillea sonorae (S. Watson) Greene. Steroids, 2021, Volume: 169 Topics: Antineoplastic Agents, Phytogenic; Cucurbitaceae; Cucurbitacins; HeLa Cells; Humans	2021
New dihydroxycucurbitacin D's from the Namib desert endemic plant Acanthosicyos horridus (!nara). Fitoterapia, 2021, Volume: 155 Topics: Cell Line, Tumor; Cucurbitaceae; Cucurbitacins; Desert Climate; Fruit; Humans; Molecular Structure; Namibia; Phytochemicals; Plant Extracts	2021
Root-secreted bitter triterpene modulates the rhizosphere microbiota to improve plant fitness. Nature plants, 2022, Volume: 8, Issue:8 Topics: Cucurbitaceae; Cucurbitacins; Microbiota; Plant Diseases; Plant Roots; Rhizosphere; Soil; Soil Microbiology	2022
Standardized phytopreparations and cucurbitacin IIb from Ibervillea sonorae (S. Watson) greene induce apoptosis in cervical cancer cells by Nrf2 inhibition. Journal of ethnopharmacology, 2022, Nov-15, Volume: 298 Topics: Apoptosis; Cucurbitaceae; Cucurbitacins; Female; HeLa Cells; Humans; NF-E2-Related Factor 2; Plant Extracts; Uterine Cervical Neoplasms	2022
Aphid adaptation to cucurbits: sugars, cucurbitacin and phloem structure in resistant and susceptible melons. BMC plant biology, 2023, May-05, Volume: 23, Issue:1 Topics: Animals; Aphids; Cucurbitaceae; Cucurbitacins; Phloem; Sugars	2023
Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species. Plant physiology and biochemistry : PPB, 2023, Volume: 201 Topics: Cucurbitaceae; Cucurbitacins; Metabolic Engineering; Metabolome; Plant Roots; Rhizobium; Transcription Factors; Transcriptome	2023