Page last updated: 2024-09-05

cucurbitacin iia and cucurbitacins

cucurbitacin iia has been researched along with cucurbitacins in 9 studies

Compound Research Comparison

Studies
(cucurbitacin iia)
Trials
(cucurbitacin iia)
Recent Studies (post-2010)
(cucurbitacin iia)
Studies
(cucurbitacins)
Trials
(cucurbitacins)
Recent Studies (post-2010) (cucurbitacins)
110111842114

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Boykin, C; Chen, YH; Fan, XE; Lu, Q; Yang, WM; Zhang, G; Zhang, RW1
He, J; He, XH; Ouyang, DY; Qiao, J; Wang, Y; Xu, LH1
Chen, GY; Chen, XB; Guo, DA; Hu, LH; Lei, M; Liu, JH; Liu, X; Meng, YH1
Cui, T; Guan, X; Huang, W; Jia, B; Wang, S; Yang, Z; Zhong, X1
Guan, SY; Li, X; Nie, HF; Wang, L; Wu, H; Yang, L; Yang, LK; Yang, Q; Zhao, MG; Zhou, SM1
Jing, S; Li, D; Li, T; Liang, Y; Song, Y; Wang, Y; Wei, Z; Yan, M; Zhang, J; Zhang, T; Zou, H; Zuo, P1
Bai, R; Bao, F; Cao, W; Chen, T; Dai, X; Ding, Z; Ji, Z; Jian, M; Kong, J; Li, L; Liu, A; Luo, L; Luo, S; Peng, Y; Wang, F; Wen, S; Xu, X; Yue, P; Zhang, Y; Zhou, G1
Huang, Q; Li, T; Ren, Y; Sun, J; Wang, J; Yao, R; Zeng, Y; Zhang, X1
An, Z; Lian, D; Liu, H; Wang, R; Xiao, H; Zeng, Y; Zhai, F; Zhang, R; Zhang, Y1

Reviews

1 review(s) available for cucurbitacin iia and cucurbitacins

ArticleYear
Cucurbitacin IIa: A review of phytochemistry and pharmacology.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:8

    Topics: Apoptosis; Caspases; Cell Cycle; Cucurbitacins; Cytokines; Cytoskeleton; Humans; Signal Transduction; Triterpenes

2021

Other Studies

8 other study(ies) available for cucurbitacin iia and cucurbitacins

ArticleYear
Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation.
    British journal of cancer, 2011, Mar-01, Volume: 104, Issue:5

    Topics: Actins; Animals; Antineoplastic Agents; Cell Line, Tumor; Cucurbitacins; Humans; Inhibitor of Apoptosis Proteins; Janus Kinase 2; Mice; Microtubule-Associated Proteins; Phosphorylation; Repressor Proteins; Signal Transduction; STAT3 Transcription Factor; Survivin

2011
Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages.
    International immunopharmacology, 2013, Volume: 16, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Autophagy; Caspase 3; Cell Line; Cucurbitacins; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Tumor Necrosis Factor-alpha

2013
Cytotoxic cucurbitane triterpenoids isolated from the rhizomes of Hemsleya amabilis.
    Fitoterapia, 2014, Volume: 94

    Topics: Alkaloids; Cell Survival; Cucurbitaceae; Cucurbitacins; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Plants, Medicinal; Rhizome; Triterpenes

2014
Simultaneous determination of cucurbitacin IIa and cucurbitacin IIb of Hemsleya amabilis by HPLC-MS/MS and their pharmacokinetic study in normal and indomethacin-induced rats.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Cucurbitacins; Indomethacin; Limit of Detection; Rats; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2016
Cucurbitacin IIa exerts antidepressant-like effects on mice exposed to chronic unpredictable mild stress.
    Neuroreport, 2017, Mar-22, Volume: 28, Issue:5

    Topics: Amygdala; Animals; Antidepressive Agents; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chronic Disease; CREB-Binding Protein; Cucurbitacins; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Hindlimb Suspension; Male; Maze Learning; Mice; Mice, Inbred BALB C; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Swimming

2017
Cucurbitacin IIa interferes with EGFR-MAPK signaling pathway leads to proliferation inhibition in A549 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 132

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Binding Sites; Cucurbitacins; ErbB Receptors; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Kinase Inhibitors

2019
Isoforskolin and Cucurbitacin IIa promote the expression of anti-inflammatory regulatory factor SIGIRR in human macrophages stimulated with Borrelia burgdorferi basic membrane protein A.
    International immunopharmacology, 2020, Volume: 88

    Topics: Anti-Inflammatory Agents; Bacterial Proteins; Borrelia burgdorferi; Cell Survival; Colforsin; Cucurbitacins; Humans; Macrophages; Receptors, Interleukin-1; THP-1 Cells; Tumor Necrosis Factor-alpha

2020
Comparative transcriptome analysis and identification of candidate genes involved in cucurbitacin IIa biosynthesis in Hemsleya macrosperma.
    Plant physiology and biochemistry : PPB, 2022, Aug-15, Volume: 185

    Topics: Cucurbitacins; Gene Expression Profiling; Gene Expression Regulation, Plant; Plant Leaves; Transcriptome

2022