Compounds > cucurbitaceae
Page last updated: 2024-09-04

cucurbitaceae and indomethacin

cucurbitaceae has been researched along with indomethacin in 4 studies

Compound Research Comparison

Studies
(cucurbitaceae)		Trials
(cucurbitaceae)		Recent Studies (post-2010)
(cucurbitaceae)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
1,649151,07329,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomycucurbitaceae (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Stasi, LC; Gonzalez, FG1
Cao, Y; Fang, QM; Wang, C; Zhang, H1
Coelho, RG; Di Stasi, LC; Gonzalez, FG; Sannomiya, M; Vilegas, W1
Gomathy, G; Palani, S; Venkatesan, D1

Other Studies

4 other study(ies) available for cucurbitaceae and indomethacin

ArticleYear
Anti-ulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Brazil; Cimetidine; Cucurbitaceae; Ethanol; Female; Flavonoids; Gastric Mucosa; Indomethacin; Male; Mice; Morphine; Motor Activity; Omeprazole; Phytotherapy; Plant Extracts; Rats; Stomach Ulcer; Tail; Toxicity Tests, Acute

2002
Anti-inflammatory and free radical scavenging activities of ethanol extracts of three seeds used as "Bolengguazi".
    Journal of ethnopharmacology, 2007, Oct-08, Volume: 114, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cucurbitaceae; Dose-Response Relationship, Drug; Edema; Female; Free Radical Scavengers; Free Radicals; Granuloma; Indomethacin; Male; Medicine, Tibetan Traditional; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Seeds

2007
Gastric anti-ulcer activity of leaf fractions obtained of polar extract from Wilbrandia ebracteata in mice.
    Natural product research, 2009, Volume: 23, Issue:1

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Biphenyl Compounds; Brazil; Cucurbitaceae; Flavonoids; Indomethacin; Mice; Picrates; Plant Extracts; Plant Leaves; Plants, Medicinal; Stomach Ulcer

2009
Gastroprotective potentials of the ethanolic extract of Mukia maderaspatana against indomethacin-induced gastric ulcer in rats.
    Natural product research, 2015, Volume: 29, Issue:22

    Topics: Animals; Anti-Ulcer Agents; Catalase; Cucurbitaceae; Dinoprostone; Gastric Juice; Gastric Mucosa; Indomethacin; Male; Malondialdehyde; Mucins; Nitric Oxide; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Stomach Ulcer; Tumor Necrosis Factor-alpha

2015