cucurbit(8)uril has been researched along with thiazole-orange* in 1 studies
1 other study(ies) available for cucurbit(8)uril and thiazole-orange
Article | Year |
---|---|
Recognition-mediated light-up of thiazole orange with cucurbit[8]uril: exchange and release by chemical stimuli.
This article reports a convenient supramolecular strategy to construct fluorescent photoswitchable molecular assemblies between a macrocyclic host, cucurbit[8]uril (CB8), and a fluorogenic dye, thiazole orange (TO). The interaction mechanism and the stable stoichiometric host-guest arrangements have been claimed on the basis of the optical absorption, steady-state and time-resolved fluorescence lifetime and anisotropy measurements, and also the geometry optimization studies. The CB8 recognized TO in its 2:2 stoichiometry exhibited spectacular fluorescence enhancement of the order of 1700 fold, which is the largest directly determined value so far reported for a dye in an organic macrocyclic system. This prospective 2CB8:2TO assembly responded to selected chemical stimuli such as metal ions, adamantylamine, and tryptophan, providing different dissociation mechanisms and demonstrating a controlled exchange and release action desired with such noncovalently linked assemblies. Positively, considering the aqueous solubility and biocompatibility of the host-guest constituents, this methodology can evolve into a general approach to deliver and operate intracellularly functional molecular components under chemical/thermal/optical trigger control, especially for therapeutic applications. Topics: Amantadine; Benzothiazoles; Bridged-Ring Compounds; Imidazoles; Metals; Quinolines; Spectrometry, Fluorescence; Tryptophan | 2012 |