cucurbit(8)uril has been researched along with indole* in 1 studies
1 other study(ies) available for cucurbit(8)uril and indole
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Cucurbit[8]uril supramolecular assembly for positively charged ultrathin films as nanocontainers.
The design of positively charged ultrathin films for surface modification is of crucial importance for biomedical applications. Herein, we report the layer-by-layer assembly of pure positively charged ultrathin films based on the host-guest interaction of cucurbit[8]uril (CB[8]). Two positively charged poly(ethylenimine)s (PEI) functionalized with guest moieties methyl viologen (MV) and indole (ID) were alternately assembled with the formation of CB[8] ternary complex under basic conditions. The growth of the (PEI-MV@CB[8]/PEI-ID) films was monitored by spectroscopic ellipsometry and quartz crystal microbalance. The morphology and structure of the films were characterized by scanning electron microscopy and UV-vis spectroscopy, respectively. These positively charged (PEI-MV@CB[8]/PEI-ID) films were very stable in the pH range from 4 to 9 but disassembled immediately when subjected to a competitive guest adamantylamine. Finally, the films were successfully employed as nanocontainers for DNA loading and subsequent directing the transfection of the adhered cells. Topics: Bridged-Ring Compounds; DNA; Drug Carriers; Imidazoles; Indoles; Nanostructures; Paraquat; Polyethyleneimine; Surface Properties; Transfection | 2013 |