Compounds > cubebin

Page last updated: 2024-09-03

cubebin and hinokinin

cubebin has been researched along with hinokinin in 11 studies

Compound Research Comparison

Studies (cubebin)	Trials (cubebin)	Recent Studies (post-2010) (cubebin)	Studies (hinokinin)	Trials (hinokinin)	Recent Studies (post-2010) (hinokinin)
34	0	17	44	0	22

Protein Interaction Comparison

Protein	Taxonomy	cubebin (IC50)	hinokinin (IC50)
Sodium-dependent noradrenaline transporter	Homo sapiens (human)		8.76
Sodium-dependent dopamine transporter	Homo sapiens (human)		8.35

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (27.27)	29.6817
2010's	7 (63.64)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Kadota, S; Tezuka, Y; Usia, T; Watabe, T	1
Dominguez, OP; Higuchi, Y; Horie, S; Ishikawa, T; Kumamoto, T; Matsumoto, K; Mochizuki, M; Nakanishi, W; Shimokawa, S; Tashima, K; Watanabe, T; Zhang, G	1
Andrade e Silva, ML; Cunha, WR; Fontana, AC; Magalhães, LG; Mortensen, OV; Pereira, AC; Souza Rezende, KC; Timple, JM	1
Almeida, VA; Bastos, JK; Carvalho, TC; Coímbra, HS; Costa, ES; Cunha, WR; Filho, AA; Furtado, NA; Lima, TC; Martins, CH; Pereira, AC; Royo, VA; Silva, ML; Silva, R; Vinhólis, AH	1
Bastos, JK; Costa, ES; da Silva Ferreira, D; de Albuquerque, S; Esperandim, VR; Pereira, AC; Saraiva, J; Silva, ML	1
Andrade E Silva, ML; Bastos, JK; Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; Esperandim, VR; Saraiva, J; Sousa Rezende, KC	1
Bastos, JK; Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; e Silva, ML; Esperandim, VR; Rezende, KC; Saraiva, J	1
Andrade e Silva, ML; Barbosa, LC; Bastos, JK; Bertanha, HC; Costa, ES; Furtado, RA; Tavares, DC; Tomazella, IM	1
Adfa, M; Koketsu, M; Ninomiya, M; Rahmad, R; Tanaka, K; Yudha S, S	1
Andriani, KF; Bastos, JK; Borges, A; Borges, CHG; Caramori, GF; Conforti, VA; Cunha, WR; da Silva Laurentiz, R; de Andrade, CQJ; E Silva, MLA; Januário, AH; Lima, TC; Lucarini, R; Parreira, RLT; Pauletti, PM; Símaro, GV; Souza, AMP; Volpe, AC	1
Ambrósio, SR; Braun, GH; de Souza, JM; Dias, GM; Januário, AH; Pauletti, PM; Pedroso, RCN; Pietro, RCLR; Pimenta, LP; Ramos, HP; Santos, MFC; Silva, MLA; Siqueira, KA; Soares, MA; Veneziani, RCS	1

Other Studies

11 other study(ies) available for cubebin and hinokinin

Article	Year
Potent CYP3A4 inhibitory constituents of Piper cubeba. Journal of natural products, 2005, Volume: 68, Issue:1 Topics: Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Fruit; Humans; Indonesia; Inhibitory Concentration 50; Ketoconazole; Lignans; Microsomes, Liver; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Piper; Plants, Medicinal; Stereoisomerism	2005
Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid. Journal of natural products, 2008, Volume: 71, Issue:7 Topics: 4-Butyrolactone; Animals; Aristolochia; Benzodioxoles; Dioxoles; Diterpenes; Ecuador; Guinea Pigs; Ileum; Lignans; Medicine, Traditional; Parasympatholytics; Plants, Medicinal; Stereoisomerism	2008
The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities. Journal of natural products, 2013, Oct-25, Volume: 76, Issue:10 Topics: 4-Butyrolactone; Attention Deficit Disorder with Hyperactivity; Benzodioxoles; Dioxoles; Dopamine; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Humans; Lignans; Molecular Structure; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism	2013
Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens. Phytotherapy research : PTR, 2007, Volume: 21, Issue:5 Topics: 4-Butyrolactone; Anti-Infective Agents; Benzodioxoles; Candida albicans; Dioxoles; Enterococcus faecalis; Lignans; Microbial Sensitivity Tests; Piper; Plant Extracts; Streptococcus	2007
Reduction of parasitism tissue by treatment of mice chronically infected with Trypanosoma cruzi with lignano lactones. Parasitology research, 2010, Volume: 107, Issue:3 Topics: 4-Butyrolactone; Animals; Benzodioxoles; beta-Galactosidase; Chagas Disease; Chronic Disease; Dioxoles; Heart; Karyometry; Lactones; Lignans; Liver; Mice; Mice, Inbred BALB C; Spleen; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi	2010
In vivo infection by Trypanosoma cruzi: a morphometric study of tissue changes in mice. Parasitology research, 2013, Volume: 112, Issue:1 Topics: 4-Butyrolactone; Animals; Antiprotozoal Agents; Benzodioxoles; Biometry; Cell Line; Chagas Disease; Dioxoles; Disease Models, Animal; Fibroblasts; Karyotyping; Lignans; Liver; Macaca mulatta; Male; Mice; Mice, Inbred BALB C; Spleen; Trypanosoma cruzi	2013
Evaluation of the in vivo therapeutic properties of (-)-cubebin and (-)-hinokinin against Trypanosoma cruzi. Experimental parasitology, 2013, Volume: 133, Issue:4 Topics: 4-Butyrolactone; Animals; Benzodioxoles; Chagas Disease; Dioxoles; Lignans; Male; Mice; Mice, Inbred BALB C; Nitroimidazoles; Piper; Trypanocidal Agents; Trypanosoma cruzi	2013
Chemopreventive effects of (-)-hinokinin against 1,2-dimethylhydrazine-induced genotoxicity and preneoplastic lesions in rat colon. Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10 Topics: 1,2-Dimethylhydrazine; 4-Butyrolactone; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinogens; Colon; Comet Assay; Dimethylhydrazines; Dioxoles; DNA Damage; Lignans; Male; Molecular Structure; Piper; Rats; Rats, Wistar; Stereoisomerism	2014
Antileukemic activity of lignans and phenylpropanoids of Cinnamomum parthenoxylon. Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Proliferation; Cinnamomum; HL-60 Cells; Humans; Lignans; Plant Extracts; U937 Cells	2016
In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (-)-cubebin derivatives (-)-hinokinin and (-)-O-benzylcubebin. Bioorganic & medicinal chemistry letters, 2017, 01-15, Volume: 27, Issue:2 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzodioxoles; Catalytic Domain; Computer Simulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyproheptadine; Dextrans; Dinoprostone; Dioxoles; Edema; Furans; Indomethacin; Ligands; Lignans; Male; Mice; Molecular Docking Simulation; Polysorbates; Rats, Wistar; Rutaceae	2017
Optimization of (-)-cubebin biotransformation to (-)-hinokinin by the marine fungus Absidia coerulea 3A9. Archives of microbiology, 2021, Volume: 203, Issue:7 Topics: 4-Butyrolactone; Absidia; Aquatic Organisms; Benzodioxoles; Biotransformation; Lignans; Seawater	2021