cromakalim has been researched along with zeneca zd 6169 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altenbach, RJ; Bai, H; Brioni, JD; Brune, ME; Buckner, SA; Carroll, WA; Cassidy, C; Chen, Y; Coghlan, MJ; Daza, AV; Drizin, I; Fey, TA; Fitzgerald, M; Gopalakrishnan, M; Gregg, RJ; Henry, RF; Holladay, MW; King, LL; Kort, ME; Kym, PR; Milicic, I; Sullivan, JP; Tang, R; Turner, SC; Whiteaker, KL; Yi, L; Zhang, H | 1 |
| Altenbach, RJ; Brune, ME; Buckner, SA; Carroll, WA; Coghlan, MJ; Daza, AV; Fabiyi, A; Gopalakrishnan, M; Henry, RF; Khilevich, A; Kort, ME; Milicic, I; Scott, VE; Smith, JC; Whiteaker, KL | 1 |
| Brown, FJ; Empfield, J; Li, JH; McConville, M; Ohnmacht, CJ; Potter-Lee, L; Russell, K; Stetz, SL; Trainor, DA; Trivedi, S | 1 |
| Do, ML; Empfield, JR; Halterman, TJ; Howe, BB; Ohnmacht, CJ; Pettinger, SJ; Russell, K; Stow, RB; Trainor, DA; Yochim, CL | 1 |
| Bertelsen, DL; Chun, A; Kau, S; Levin, RM; Murphy, J | 1 |
| Bonev, A; Heppner, TJ; Kau, ST; Li, JH; Nelson, MT | 1 |
| Jow, B; Numann, R | 1 |
| Bonev, AD; Heppner, TJ; Herrera, GM; Nelson, MT; Petkov, GV | 1 |
| Brading, AF; Ito, Y; Masaki, I; Sueishi, K; Takano, M; Teramoto, N; Yonemitsu, Y; Yunoki, T | 1 |
| Brioni, JD; Brune, ME; Coghlan, MJ; Fabiyi, AC; Gopalakrishnan, M; Lynch, JJ | 1 |
| Brune, ME; Buckner, SA; Coghlan, M; Daza, A; Fey, TA; Gopalakrishnan, M; Milicic, I | 1 |
| Brown, FJ; Ceccarelli, C; Chun, AL; Empfield, JR; Forst, JM; Frank, CA; Gibson, KH; Grant, TL; Harris, RJ; Howe, BB; Hulsizer, JM; Kau, ST; Lewis, JJ; Lin, MM; Masek, BB; Mayhugh, DR; McLaren, FM; Neilson, KL; Ohnmacht, CJ; Russell, K; Shapiro, HS; Silverman, SM; Smith, RW; Trainor, DA; Warwick, PJ | 1 |
| Brune, ME; Buckner, SA; Carroll, WA; Castle, NA; Coghlan, MJ; Daza, AV; Fabiyi, A; Gopalakrishnan, M; Milicic, I; Scott, VE; Sullivan, JP; Turner, SC; White, TK | 1 |
13 other study(ies) available for cromakalim and zeneca zd 6169
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of a novel series of 2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide K(ATP) channel openers: discovery of (-)-(9S)-9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-b]quinolin-8(4H)
Topics: Adenosine Triphosphate; Animals; Cyclic S-Oxides; Electric Stimulation; Guinea Pigs; Hemodynamics; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Potassium Channels; Quinolones; Stereoisomerism; Structure-Activity Relationship; Swine; Urinary Bladder; Urodynamics | 2004 |
Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium channel opener.
Topics: Adenosine Triphosphate; Animals; Aza Compounds; Cell Line; Crystallography, X-Ray; Dihydropyridines; Electric Stimulation; Heterocyclic Compounds, 3-Ring; In Vitro Techniques; Ion Channel Gating; Mice; Muscle Contraction; Muscle, Smooth; Naphthalenes; Potassium Channels, Inwardly Rectifying; Stereoisomerism; Structure-Activity Relationship; Swine; Urinary Bladder | 2006 |
K-channel opening activity of ZD6169 and its analogs: effect on 86Rb efflux and 3H-P1075 binding in bladder smooth muscle.
Topics: Amides; Animals; Benzophenones; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Kinetics; Muscle, Smooth; Potassium Channels; Pyridines; Pyrroles; Rubidium; Urinary Bladder; Vasodilator Agents | 1995 |
ZENECA ZD6169: a novel KATP channel opener with in vivo selectivity for urinary bladder.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Heart Rate; Male; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Urinary Bladder | 1995 |
Comparative effects of intravesical versus extravesical administration of ZD6169 and cromakalim on the response of the in vitro rat whole bladder to field stimulation.
Topics: Amides; Animals; Benzophenones; Benzopyrans; Cromakalim; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Urinary Bladder | 1996 |
Zeneca ZD6169 activates ATP-sensitive K+ channels in the urinary bladder of the guinea pig.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Enzyme Activation; Glyburide; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Muscle, Smooth; Potassium Channels; Protein Kinase C; Pyrroles; Urinary Bladder | 1996 |
The effects of ZD6169 on the ATP-dependent K(+) current (I(K)(ATP)) in isolated cat ventricular myocytes.
Topics: Action Potentials; Amides; Animals; Antihypertensive Agents; ATP-Binding Cassette Transporters; Benzophenones; Cats; Cell Separation; Cromakalim; Glyburide; Heart Ventricles; Hypoglycemic Agents; In Vitro Techniques; KATP Channels; Myocardium; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying | 1999 |
Low levels of K(ATP) channel activation decrease excitability and contractility of urinary bladder.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Amides; Animals; Benzophenones; Cromakalim; Glyburide; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Channels; Urinary Bladder | 2001 |
Dual action of ZD6169, a novel K(+) channel opener, on ATP-sensitive K(+) channels in pig urethral myocytes.
Topics: Adenosine Triphosphate; Amides; Animals; Anti-Arrhythmia Agents; Benzophenones; Cells, Cultured; COS Cells; Cromakalim; Electric Conductivity; Female; Glyburide; Hypoglycemic Agents; Imidazoles; Ion Channel Gating; Membrane Potentials; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Swine; Time Factors; Urethra; Vasodilator Agents | 2001 |
In vivo evaluation of the potency and bladder-vascular selectivity of the ATP-sensitive potassium channel openers (-)-cromakalim, ZD6169 and WAY-133537 in rats.
Topics: Amides; Animals; Benzophenones; Calcium Channels; Cromakalim; Cyclobutanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Male; Muscarinic Antagonists; Muscle Contraction; Nitriles; Rats; Rats, Sprague-Dawley; Reflex, Abnormal; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder, Neurogenic; Vasodilator Agents | 2003 |
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Carbachol; Cholinergic Agonists; Cromakalim; Cyclic S-Oxides; Diazoxide; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanidines; Histamine; Hypertrophy; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Chloride; Pyridines; Quinolones; Serotonin; Serotonin Agents; Swine; Urinary Bladder; Urinary Bladder Neck Obstruction; Vasodilator Agents | 2006 |
N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP potassium channel openers. Modifications on the western region.
Topics: Amides; Animals; Cricetinae; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Channels; Rats; Structure-Activity Relationship; Urinary Bladder; Urinary Incontinence | 1996 |
Structure-activity relationship of a novel class of naphthyl amide KATP channel openers.
Topics: Amides; Animals; ATP-Binding Cassette Transporters; Blood Pressure; Cell Line; Fluorescent Dyes; Humans; Hypertrophy; Male; Membrane Potentials; Muscle Contraction; Naphthalenes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Drug; Structure-Activity Relationship; Sulfonylurea Receptors; Swine; Transfection; Urinary Bladder | 2003 |