cromakalim has been researched along with piperidines in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (78.26) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shikada, K; Tanaka, S | 3 |
| Shikada, K; Tanaka, S; Yamamoto, A | 3 |
| Arakawa, C; Masuda, Y; Shigenobu, K; Tanaka, S; Yokoyama, T | 1 |
| Kageyama, C; Shigenobu, K; Watanabe, M | 1 |
| Arakawa, C; Kasuya, Y; Masuda, Y; Miyajima, M; Shigenobu, K; Tanaka, S; Yamashita, T | 1 |
| Dzwonczyk, S; Grover, GJ; Sargent, CA; Sleph, PG; Smith, MA | 1 |
| Fujikura, N; Kawamura, N; Masuda, Y; Tanaka, S; Yamashita, T | 1 |
| Masuda, Y; Tanaka, S; Yamashita, T | 1 |
| Kato, Y; Matsuda, T; Okazaki, K; Shigenobu, K; Tanaka, H | 1 |
| Hiley, CR; White, R | 2 |
| Kato, Y; Matsuda, T; Noguchi, K; Okazaki, K; Saito, W; Shigenobu, K; Tanaka, H | 1 |
| Aida, M; Saito, W; Saito, Y; Sasaki, M; Shigenobu, K; Tanaka, H; Tanaka, Y | 1 |
| Imaizumi, Y; Muraki, K; Tokuno, T; Watanabe, M | 1 |
| Bourreau, JP; Huang, Y; Shen, S | 1 |
| Chen, IJ; Chiang, LC; Lin, CY; Lin, RJ; Shen, KP; Wu, BN | 1 |
| Imai, T; Koike, K; Okamoto, T; Shigenobu, K; Tanaka, H; Tanaka, Y; Yamamoto, Y | 1 |
| Pan, YP; Wang, XL; Xu, XH | 1 |
| Dinc, M; Oz, M; Shippenberg, TS; Yang, KH | 1 |
23 other study(ies) available for cromakalim and piperidines
| Article | Year |
|---|---|
Potassium channel openers, NIP-121 and cromakalim, enhance the relaxation induced by sodium nitroprusside in the guinea-pig isolated trachea.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Drug Interactions; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles; SRS-A; Trachea; Vasodilator Agents | 1992 |
Modulation of guinea-pig tracheal smooth muscle responsiveness by the potassium channel openers NIP-121 and cromakalim.
Topics: Animals; Benzopyrans; Cromakalim; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles; Trachea; Vasodilator Agents | 1992 |
Effects of anti-asthma drugs and potassium channel openers on neurally-mediated contraction of isolated guinea pig trachea.
Topics: Acetylcholine; Aminophylline; Animals; Benzopyrans; Cromakalim; Electric Stimulation; Guinea Pigs; Hydrocortisone; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles; Trachea | 1992 |
The antihypertensive property of NIP-121, a novel potassium channel opener in rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Species Specificity | 1991 |
Action potential shortening and negative inotropic effects of a novel potassium channel opener, NIP-121, as compared with cromakalim in guinea pig ventricular myocardium.
Topics: Action Potentials; Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Depression, Chemical; Guinea Pigs; Heart Rate; Heart Ventricles; Male; Myocardial Contraction; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles | 1991 |
NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea-pig isolated trachea.
Topics: Animals; Arachidonic Acid; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Piperidines; Potassium Channels; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pyrroles; Sulfonamides; Trachea | 1991 |
Potassium channel opening properties of a novel compound, NIP-121, cromakalim and nicorandil in rat aorta and portal vein.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Oxadiazoles; Phentolamine; Piperidines; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Inbred Strains; Rubidium Radioisotopes | 1991 |
Effect of potassium channel blockade on the anti-ischemic actions of mechanistically diverse agents.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Glyburide; Lidocaine; Male; Piperidines; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Inbred Strains | 1991 |
K+ channel openers produce epithelium-dependent relaxation of the guinea-pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Benzopyrans; Cromakalim; Epithelium; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Thromboxane A2; Trachea; Vasoactive Intestinal Peptide | 1995 |
Comparative study of vasodilator effects of the potassium channel openers NIP-121 and levcromakalim in dogs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthesia; Animals; Benzopyrans; Coronary Circulation; Cromakalim; Dogs; Female; Hemodynamics; Male; Oxadiazoles; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Potassium channel openers relax A23187-induced nifedipine-resistant contraction of rat aorta.
Topics: Animals; Aorta; Benzopyrans; Calcimycin; Cromakalim; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Oxadiazoles; Piperidines; Pyrroles; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1994 |
K+ channel-opening properties of a novel compound, NIP-121, in guinea pig myocardium as compared with those of cromakalim.
Topics: Action Potentials; Adenosine Triphosphate; Analysis of Variance; Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Guinea Pigs; Hypoglycemic Agents; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Oxadiazoles; Papillary Muscles; Patch-Clamp Techniques; Piperidines; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Effect of the K+ channel openers NIP-121 and cromakalim on melittin-induced relaxation of guinea-pig isolated trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Cromakalim; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Epithelium; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Melitten; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Phospholipases A; Phospholipases A2; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Thromboxane A2; Trachea | 1996 |
Endothelium and cannabinoid receptor involvement in levcromakalim vasorelaxation.
Topics: Animals; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanidines; Male; Mesenteric Arteries; Pinacidil; Piperidines; Potassium Channels; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vasodilation; Vasodilator Agents | 1997 |
Temperature-sensitive effects of potassium channel openers on isolated guinea pig myocardium and aorta.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Aorta, Thoracic; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; Glyburide; Guanidines; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardium; Norepinephrine; Oxadiazoles; Patch-Clamp Techniques; Pinacidil; Piperidines; Potassium Channels; Temperature; Vasodilator Agents | 1998 |
Differential sensitivity to ATP-sensitive potassium channel openers of norepinephrine-induced contraction of guinea pig and rat aorta.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Cromakalim; Diltiazem; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxadiazoles; Piperidines; Potassium Channels; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation | 1998 |
The actions of the cannabinoid receptor antagonist, SR 141716A, in the rat isolated mesenteric artery.
Topics: Animals; Benzimidazoles; Calcium; Cannabinoids; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Penicillamine; Piperidines; Potassium Channels; Pyrazoles; Rats; Rats, Wistar; Rimonabant | 1998 |
Effects of K+ channel modulators on the relationship between action potential duration and Ca2+ transients in single ventricular myocytes of the guinea pig.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cromakalim; Glyburide; Guinea Pigs; Heart Ventricles; Hypoglycemic Agents; Male; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Pyridines; Time Factors; Vasodilator Agents; Ventricular Function | 1999 |
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle.
Topics: Acetylcholine; Animals; Calcium; Cattle; Cromakalim; Diamines; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical; Tetraethylammonium; Trachea | 2000 |
A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Cromakalim; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Heart Rate; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphoric Diester Hydrolases; Piperidines; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Solubility; Vasodilation; Vasodilator Agents; Xanthine; Xanthines | 2001 |
Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Apamin; Barium; Benzimidazoles; Calcium Channel Blockers; Cation Transport Proteins; Cromakalim; Diltiazem; Ether-A-Go-Go Potassium Channels; Female; Glyburide; Guinea Pigs; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Contraction; Muscle, Smooth; Nisoldipine; Parasympatholytics; Peptides; Periodicity; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Pyridines; Small-Conductance Calcium-Activated Potassium Channels; Urinary Bladder | 2001 |
[High throughput screening method of potassium channel regulators].
Topics: 4-Aminopyridine; Animals; Barbiturates; Calcium Channel Blockers; Cromakalim; Isoxazoles; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Quinidine; Rats | 2004 |
The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes.
Topics: Animals; Arachidonic Acids; Calcium; Camphanes; Cromakalim; Egtazic Acid; Endocannabinoids; Female; Glyburide; KATP Channels; Oocytes; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rimonabant; Xenopus laevis | 2007 |