cromakalim has been researched along with phenylephrine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.71) | 18.7374 |
| 1990's | 14 (40.00) | 18.2507 |
| 2000's | 16 (45.71) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, K; Nishimura, K; Ota, M | 1 |
| MacLeod, KM; Ray, A | 1 |
| Cheung, WM; Falotico, R; Haertlein, B; Keiser, J; Tobia, A | 1 |
| Buckingham, RE | 1 |
| Schwietert, R; van Zwieten, PA; Wilffert, B; Wilhelm, D | 1 |
| Högestätt, ED; Waldeck, K; Zygmunt, PM | 1 |
| Grundemar, L; Högestätt, ED; Zygmunt, PM | 1 |
| Coleman, HA; Parkington, HC; Tare, M; Tonta, MA | 1 |
| Ashford, ML; Khan, RN; Morrison, JJ; Smith, SK | 1 |
| Johns, EJ | 1 |
| Griffin, A | 1 |
| Balderrama, DS; Eichinger, MR; Herrera, GM; Resta, JM; Resta, TC; Richardson, LA; Walker, BR | 1 |
| Huang, Y; Kwok, KH | 1 |
| Beattie, DK; Davies, AH; Gosling, M; Powell, JT | 1 |
| Autore, G; d'Emmanuele di Villa Bianca, R; Lippolis, L; Pinto, A; Sorrentino, L; Sorrentino, R | 1 |
| Bouchard, JF; Dumont, EC; Lamontagne, D | 1 |
| Damron, DS; Doi, S; Horibe, M; Murray, PA; Ogawa, K; Tanaka, S | 1 |
| Cai, J; Imai, S; Luo, D; Nakazawa, M; Yoshida, Y | 1 |
| Beattie, DK; Davies, AH; Gosling, M; McGregor, E; Powell, JT; Ribbons, DM | 1 |
| Berg, G; Butler, J; Dominiczak, AF; Hamilton, CA; McIntosh, L; O'Dowd, G; Pathi, V; Reid, JL; Williams, R | 1 |
| Christ, GJ; Giraldi, A; Melman, A; Spektor, M; Venkateswarlu, K; Wang, HZ; Zhao, W | 1 |
| Dojo, M; Hatano, Y; Iranami, H; Kimoto, Y; Kinoshita, H; Nakahata, K | 2 |
| Dora, KA; Garland, CJ; Spitaler, MM; Takano, H | 1 |
| Dubrovska, G; Essin, K; Gollasch, M; Huang, Y; Luft, FC; Tsang, SY; Verlohren, S | 1 |
| Ghosh, M; Hanna, ST; McNeill, JR; Wang, R | 1 |
| Clapp, LH; Fry, CH; Orie, NN | 1 |
| Bigat, Z; Eksert, B; Gölbasi, I; Ozdem, SS; Usta, C | 1 |
| Khalil, RA; Raffetto, JD; Ross, RL | 1 |
| Ari, N; Aslamaci, S; Irat, AM; Karasu, C | 1 |
| Carter, CB; Dearman, JA; Hester, RL; Hodnett, BL; Xiang, L | 1 |
| Azma, T; Haba, M; Hama-Tomioka, K; Hatakeyama, N; Hatano, Y; Kinoshita, H; Matsuda, N; Yamazaki, M | 1 |
| Brochu, M; Houde, V; Provencher, M; St-Louis, J | 1 |
| Clapp, LH; Muzyamba, M; Nwokocha, CR; Orie, NN; Osim, EE; Owu, DU | 1 |
| Hamaguchi, S; Kanae, H; Kato, K; Kusakabe, T; Namekata, I; Tanaka, H; Wakasugi, Y | 1 |
35 other study(ies) available for cromakalim and phenylephrine
| Article | Year |
|---|---|
Existence of two components in the tonic contraction of rat aorta mediated by alpha 1-adrenoceptor activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Carbamates; Cromakalim; In Vitro Techniques; Isoquinolines; Lanthanum; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Phenylcarbamates; Phenylephrine; Phosphatidylinositols; Piperazines; Protease Inhibitors; Pyrroles; Rats | 1991 |
Adrenergic-cholinergic interactions in left atria: a study using K+ channel agonists, antagonist and pertussis toxin.
Topics: 4-Aminopyridine; Animals; Benzopyrans; Carbachol; Cromakalim; Cyclic AMP; Dogs; Female; Guanidines; Heart; Isoproterenol; Male; Myocardial Contraction; Parasympathetic Nervous System; Pertussis Toxin; Phenylephrine; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Sympathetic Nervous System; Virulence Factors, Bordetella | 1990 |
Increased vasodilator responsiveness to BRL 34915 in spontaneously hypertensive versus normotensive rats: contrast with nifedipine.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilation | 1989 |
Studies on the anti-vasoconstrictor activity of BRL 34915 in spontaneously hypertensive rats; a comparison with nifedipine.
Topics: Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Female; Hypertension; Infusions, Intravenous; Nifedipine; Norepinephrine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vasoconstriction; Vasopressins | 1988 |
Functional study on the effects of nifedipine, cromakalim, and the absence of extracellular Ca2+ on alpha 1-adrenoceptor-mediated excitation-contraction coupling in isolated rat portal vein: comparison with depolarization-mediated excitation-contraction c
Topics: Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Parasympatholytics; Phenylephrine; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1993 |
The endothelium mediates a nitric oxide-independent hyperpolarization and relaxation in the rat hepatic artery.
Topics: Acetylcholine; Animals; Arginine; Benzopyrans; Cell Polarity; Cromakalim; Endothelium, Vascular; Female; Hepatic Artery; Indomethacin; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nimodipine; Nitric Oxide; Nitroarginine; Phenylephrine; Prazosin; Pyrroles; Rats; Rats, Sprague-Dawley | 1994 |
Light-dependent effects of zinc protoporphyrin IX on endothelium-dependent relaxation resistant to N omega-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Benzopyrans; Biliverdine; Carbon Monoxide; Cromakalim; Darkness; Endothelium, Vascular; Female; Heme Oxygenase (Decyclizing); Hepatic Artery; In Vitro Techniques; Indomethacin; Light; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Phenylephrine; Potassium; Potassium Channels; Protoporphyrins; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1994 |
Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium.
Topics: Acetylcholine; Action Potentials; Animals; Arteries; Autonomic Nervous System; Benzopyrans; Cromakalim; Endothelium, Vascular; Female; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Pilocarpine; Pyrroles; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tail | 1994 |
The effects of potassium channel openers on isolated pregnant human myometrium before and after the onset of labor: potential for tocolysis.
Topics: Benzopyrans; Cromakalim; Female; Guanidines; Humans; In Vitro Techniques; Labor Onset; Myometrium; Oxytocin; Phenylephrine; Pinacidil; Potassium Channels; Potassium Chloride; Pregnancy; Pyrroles; Sulfonylurea Compounds; Tocolytic Agents; Uterine Contraction | 1993 |
Effect of BRL 38227 on the adrenergic regulation of the kidney vasculature of the rat.
Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Electric Stimulation; Kidney; Male; Methoxamine; Norepinephrine; Phenylephrine; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Renal Circulation; Sympathetic Nervous System; Vasoconstriction; Vasodilator Agents | 1993 |
The effect of K+ channel openers on submucosal gland function and epithelial transport of the ferret trachea, in vitro.
Topics: Albumins; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Dose-Response Relationship, Drug; Epithelium; Female; Ferrets; In Vitro Techniques; Male; Methacholine Chloride; Muramidase; Muscle, Smooth; Phenylephrine; Potassium Channels; Pyridines; Pyrroles; Trachea | 1995 |
Glibenclamide does not reverse attenuated vasoreactivity to acute or chronic hypoxia.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Benzopyrans; Blood Gas Analysis; Blood Pressure; Chronic Disease; Cromakalim; Glyburide; Heart Rate; Hemodynamics; Hypoglycemic Agents; Hypoxia; Male; Phenylephrine; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstrictor Agents | 1995 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotoxin; Colforsin; Cromakalim; Cyclic AMP; Dose-Response Relationship, Drug; Fenoterol; Glyburide; Isoproterenol; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Pyrroles; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
The effects of potassium channel openers on saphenous vein exposed to arterial flow.
Topics: Arteries; Blood Flow Velocity; Chromans; Cromakalim; Diazoxide; Guanidines; Humans; In Vitro Techniques; Phenylephrine; Pinacidil; Potassium Channels; Pyrrolidines; Saphenous Vein; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1998 |
Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Cromakalim; Enzyme Inhibitors; Glyburide; Heart Rate; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Vasodilator Agents | 1999 |
Modification of vasodilator response in streptozotocin-induced diabetic rat.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Heart; Iloprost; Male; Mesenteric Arteries; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
K(+) channel inhibition, calcium signaling, and vasomotor tone in canine pulmonary artery smooth muscle.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Calcium Signaling; Cells, Cultured; Cromakalim; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Pulmonary Artery; Thapsigargin; Vasoconstriction; Vasodilator Agents; Vasomotor System | 2000 |
Effects of three different Ca(2+) pump ATPase inhibitors on evoked contractions in rabbit aorta and activities of Ca(2+) pump ATPases in porcine aorta.
Topics: Animals; Aorta; Caffeine; Calcium; Calcium-Transporting ATPases; Cromakalim; Drug Interactions; Enzyme Inhibitors; Hydroquinones; In Vitro Techniques; Indoles; Microsomes; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rabbits; Swine; Thapsigargin; Vanadates; Vasoconstriction; Vasodilator Agents | 2000 |
Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways.
Topics: Adenosine; Amides; Cromakalim; Cycloheximide; Enzyme Inhibitors; Gadolinium; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Pulsatile Flow; Pyridines; rho-Associated Kinases; Saphenous Vein; Serotonin; Signal Transduction; Stents; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Vasorelaxant properties of isolated human radial arteries: comparison with internal mammary arteries.
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Artery Bypass; Cromakalim; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Nicorandil; Nitroprusside; Phenylephrine; Potassium Chloride; Radial Artery; Vasoconstriction; Vasodilation; Vasodilator Agents | 2002 |
Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers.
Topics: Adenosine Triphosphate; Cromakalim; Culture Techniques; Dose-Response Relationship, Drug; Erectile Dysfunction; Glyburide; Humans; Male; Muscle, Smooth, Vascular; Penile Erection; Penis; Phenylephrine; Pinacidil; Potassium Channels; Vasodilation; Vasodilator Agents | 2002 |
Ketamine stereoselectively affects vasorelaxation mediated by ATP-sensitive K(+) channels in the rat aorta.
Topics: Animals; Aorta, Thoracic; ATP-Binding Cassette Transporters; Cromakalim; Endothelium, Vascular; In Vitro Techniques; KATP Channels; Ketamine; Male; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Stereoisomerism; Vasoconstrictor Agents; Vasodilation | 2002 |
Mexiletine differentially modulates vasorelaxation mediated by adenosine triphosphate-sensitive K+ channels in aortas from normotensive and hypertensive rats.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; ATP-Binding Cassette Transporters; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Hypertension; Hypoglycemic Agents; KATP Channels; Male; Mexiletine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Phenylephrine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2003 |
Spreading dilatation in rat mesenteric arteries associated with calcium-independent endothelial cell hyperpolarization.
Topics: Acetylcholine; Aniline Compounds; Animals; Barium; Calcium; Cromakalim; Endothelial Cells; Fluorescent Dyes; Glyburide; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Fluorescence; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Organic Chemicals; Patch-Clamp Techniques; Phenylephrine; Propidium; Rats; Rats, Wistar; Vasodilation; Xanthenes | 2004 |
Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Adipose Tissue; Amifampridine; Animals; Apamin; Barium; Cromakalim; Delayed Rectifier Potassium Channels; Endothelin-1; Glyburide; Male; Mesenteric Artery, Superior; Peptides; Phenylephrine; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Serotonin; Tetraethylammonium; Vascular Resistance; Vasodilation; Viscera | 2004 |
Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Canada; Cromakalim; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Electrophysiology; Endothelium, Vascular; Glyburide; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nephrectomy; Phenylephrine; Potassium Channels; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 2004 |
Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Apamin; Barium Compounds; Charybdotoxin; Chlorides; Cromakalim; Cyclic AMP; DDT; Dose-Response Relationship, Drug; Epoprostenol; Fluoxetine; Glyburide; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurotoxins; Phenylephrine; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Vasodilator Agents | 2006 |
The role of potassium channels in the vasodilatory effect of levosimendan in human internal thoracic arteries.
Topics: Aged; Cardiotonic Agents; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Humans; Hydrazones; Mammary Arteries; Middle Aged; Phenylephrine; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Pyridazines; Simendan; Tissue Culture Techniques; Vasodilation; Vasodilator Agents | 2006 |
Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation.
Topics: Animals; Cromakalim; Cyclooxygenase Inhibitors; Dilatation, Pathologic; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; In Vitro Techniques; Indomethacin; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Chloride; Rats; Varicose Veins; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vena Cava, Inferior | 2007 |
Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones.
Topics: Aged; Cromakalim; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Mammary Arteries; Middle Aged; Nitroprusside; Phenylephrine; Pioglitazone; Potassium Channel Blockers; Potassium Chloride; Rosiglitazone; Thiazolidinediones; Vasoconstriction | 2006 |
K(ATP)-mediated vasodilation is impaired in obese Zucker rats.
Topics: Animals; Arterioles; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Hypoglycemic Agents; Iloprost; Male; Muscle, Skeletal; Obesity; Phenylephrine; Potassium Channels; Rats; Rats, Zucker; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2008 |
Beneficial effect of propofol on arterial adenosine triphosphate-sensitive K+ channel function impaired by thromboxane.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Blotting, Western; Cromakalim; Dose-Response Relationship, Drug; Electrophysiology; In Vitro Techniques; KATP Channels; Male; NADPH Oxidases; Oxidative Stress; Phenylephrine; Propofol; Rats; Rats, Wistar; Superoxides; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
Topics: Aldosterone; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Canrenoic Acid; Cromakalim; Female; KATP Channels; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Channels, Calcium-Activated; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilator Agents | 2012 |
Attenuated vascular responsiveness to K+ channel openers in diabetes mellitus: the differential role of reactive oxygen species.
Topics: Acetophenones; Acetylcholine; Animals; Blood Glucose; Blood Vessels; Body Weight; Cromakalim; Diabetes Mellitus; Flavanones; Free Radical Scavengers; Ion Channel Gating; Male; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vasoconstriction; Vasodilation | 2013 |
Pathological prolongation of action potential duration as a cause of the reduced alpha-adrenoceptor-mediated negative inotropy in streptozotocin-induced diabetic mice myocardium.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cromakalim; Depression, Chemical; Diabetes Mellitus, Experimental; Male; Mice, Inbred Strains; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, alpha; Streptozocin | 2017 |