cromakalim has been researched along with nifedipine in 95 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (13.68) | 18.7374 |
| 1990's | 69 (72.63) | 18.2507 |
| 2000's | 11 (11.58) | 29.6817 |
| 2010's | 2 (2.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berdeaux, A; Drieu la Rochelle, C; Giudicelli, JF; Richard, V | 1 |
| Huang, LJ; Huang, TF; Kuo, SC; Sun, SS; Teng, CM; Yu, SM | 1 |
| Bourreau, JP; Daniel, EE; Kwan, CY | 2 |
| Duty, S; Weston, AH | 1 |
| Adachi, H; Kodama, K; Ogawa, T; Ohhara, H | 1 |
| Aoki, K; Fukunari, A; Katoh, A; Nakajima, T; Setoguchi, M; Shinagawa, K; Shinohara, T; Tahara, T; Yamanaka, T; Yaoka, O | 1 |
| Dockrell, ME; Haynes, WG; Olverman, HJ; Waugh, CJ; Webb, DJ; Williams, BC | 2 |
| Ito, K; Nishimura, K; Ota, M | 1 |
| Fukushima, H; Izawa, T; Kashiwabara, T; Nakajima, S; Nishikori, K | 1 |
| Arch, JR; Bowring, NE; Buckle, DR; Clarke, GD; Taylor, JF | 1 |
| Asano, M; Masuzawa, K; Matsuda, T | 2 |
| Brown, TJ; Raeburn, D | 1 |
| Bray, KM; Brown, TJ; Duty, S; Edwards, G; Longmore, J; Newgreen, DT; Weston, AH | 1 |
| Fromm-Freeck, S; Hayes, L; Howe, BB; Kau, ST; Kitada, S; Levin, RM; Wein, AJ | 1 |
| McHarg, AD; Southerton, JS; Weston, AH | 1 |
| Satoh, E; Taira, N; Yanagisawa, T | 1 |
| Duty, S; Paciorek, PM; Waterfall, JF; Weston, AH | 1 |
| Abe, Y; Aki, Y; Fukui, K; Iwao, H; Shoji, T; Tamaki, T | 1 |
| Wilson, C | 1 |
| Cooper, SM; Wilson, C | 1 |
| Clapham, JC; Longman, SD | 1 |
| Jones, AW; Post, JM; Smith, JM | 1 |
| Brown, TJ; Raeburn, D; Sweetland, J | 1 |
| Hashimoto, H; Taira, N; Yanagisawa, T | 1 |
| Cheung, WM; Falotico, R; Haertlein, B; Keiser, J; Tobia, A | 1 |
| Clapham, JC; Wilson, C | 1 |
| Coldwell, MC; Howlett, DR | 1 |
| Arch, JR; Buckle, DR; Bumstead, J; Clarke, GD; Taylor, JF; Taylor, SG | 1 |
| Akbarali, HI; Bieger, D; Ohia, SE; Triggle, CR | 1 |
| Buckingham, RE | 1 |
| Izawa, T; Izumi, H; Jinno, Y; Kaneta, S; Ogawa, N; Okada, Y; Tanaka, Y | 1 |
| Asano, M; Fujikura, T; Masuda, N; Matsumoto, Y; Shibasaki, K; Shirai, Y; Taguchi, T; Takenaka, T; Tsuzuki, R; Uchida, W | 1 |
| Aiyar, J; Auperin, DD; Chandy, KG; Grissmer, S; Gutman, GA; Hanson, DC; Karmilowicz, MJ; Mather, RJ; Nguyen, AN | 1 |
| Maggi, CA; Meini, S; Santicioli, P | 1 |
| Brock, GB; Lue, TF; Nunes, L; Riemer, RK; Tanagho, EA; von Heyden, B | 1 |
| Jino, H; Kurahashi, K; Nakata, Y; Shimizu, Y; Shirahase, H; Usui, H | 1 |
| Schwietert, R; van Zwieten, PA; Wilffert, B; Wilhelm, D | 1 |
| Fukushima, H; Jinno, Y; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Ginkawa, M; Kontani, H; Sakai, T | 1 |
| Kam, KL; Pfaffendorf, M; van Zwieten, PA | 2 |
| Gonzalez de la Fuente, P; Marthan, R; Savineau, JP | 1 |
| Masuda, Y; Tanaka, S; Yamashita, T | 1 |
| Izawa, T; Jinno, Y; Miwa, A; Ogawa, N; Yokoyama, T | 1 |
| Fukushima, H; Izawa, T; Kashiwabara, T; Ogawa, N | 1 |
| Criddle, DN; Greenwood, IA; Weston, AH | 1 |
| Chen, XJ; Liu, TF | 1 |
| Jinkawa, M; Kontani, H; Sakai, T | 1 |
| McGrath, JC; Smith, GC | 1 |
| Freed, AN; Lindeman, KS | 1 |
| Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC | 1 |
| Creed, KE; Malmgren, A | 1 |
| Shen, YT; Vatner, SF | 1 |
| Barth, HL; Hempelmann, RG; Mehdorn, HM; Pradel, RH; Ziegler, A | 1 |
| Criddle, DN; de Moura, RS; Jazbik, W | 1 |
| Hollingsworth, M; Hughes, SJ | 1 |
| Asano, M; Ito, K; Kuwako, M; Nomura, Y; Shibuya, M; Sugita, K; Suzuki, Y | 1 |
| Izawa, T; Izumi, H; Kawahara, J; Okada, Y | 1 |
| Angus, JA; Fujiwara, T | 1 |
| Elliott, KR; Hollingsworth, M; Hughes, SJ | 1 |
| Endo, M; Izawa, T; Izumi, H; Jinno, Y; Kawahara, J; Takeuchi, A | 1 |
| Cameron, AD; Cameron, IT; Greer, IA; Martin, W; McGrath, JC; Norman, JE; Ward, LM | 1 |
| Canzoniero, LM; Choi, DW; Dugan, LL; Farhangrazi, ZS; Gwag, BJ; Sensi, SL; Tian, M; Yeh, CH; Ying, HS; Yu, SP | 1 |
| Bianchi, L; Boselli, C; Grana, E | 1 |
| Aisaka, K; Hirata, Y; Mabuchi, Y; Miyai, H | 1 |
| Brading, AF; Teramoto, N | 1 |
| Barbieri, A; Bianchi, L; Boselli, C; Grana, E | 1 |
| Harada, K; Kawahara, J; Kusaka, M; Okada, Y; Tokiwa, T; Uzumaki, H | 1 |
| Huang, S; Iino, S; Nakayama, S; Tomita, T | 1 |
| Izawa, T; Kashiwabara, T; Kawahara, J; Ogawa, N; Okada, Y | 1 |
| Kang, SY; Kim, MJ; Kim, ND; Park, JH; Schini-Kerth, VB | 1 |
| Aisaka, K; Hirata, Y; Kanada, A; Mabuchi, Y; Miyai, H | 1 |
| De Los Angeles, J; Jagadeesh, JM; Jing, L; Miller, DD; Patil, PN | 1 |
| Kankaanranta, H; Li, L; Vaali, K; Vapaatalo, H | 1 |
| Boselli, C; Grana, E | 1 |
| Criddle, DN; Leal-Cardoso, JH; Santos, GC; Scarparo, HC | 1 |
| Bourreau, JP; Huang, Y; Shen, S | 1 |
| Chen, Q; Wang, XL | 1 |
| Chan, HY; Chen, ZY; Huang, Y; Ming, WC; Tsang, SY; Yao, X | 1 |
| Muraki, K | 1 |
| Brading, AF; Hashitani, H; Suzuki, H | 1 |
| Pan, YP; Wang, XL; Xu, XH | 1 |
| Al-Mehdi, AB; Chatterjee, S; Fisher, AB; Manevich, Y; Wei, Z | 1 |
| Danisman, N; Polat, B; Tufan, H | 1 |
| Hirota, S; Janssen, LJ | 1 |
| Baker, PN; Fyfe, GK; Greenwood, SL; Sibley, CP; Williams, JL | 1 |
| Anderson, L; Higgins, C; Martin, W; Nelson, SM; Norman, JE | 1 |
| Brochu, M; Houde, V; Provencher, M; St-Louis, J | 1 |
| Holstein-Rathlou, NH; Jensen, LJ; Ngo, AT; Riemann, M; Torp-Pedersen, C | 1 |
| Arch, JR; Buckle, DR; Fenwick, AE; Houge-Frydrych, CS; Pinto, IL; Smith, DG; Taylor, SG; Tedder, JM | 1 |
| Ashwood, VA; Buckingham, RE; Cassidy, F; Evans, JM; Faruk, EA; Hamilton, TC; Nash, DJ; Stemp, G; Willcocks, K | 1 |
| Brandriff, B; Cahalan, M; Chandy, G; Chandy, KG; Copeland, NG; Dukes, ID; Gutman, GA; Hustad, CM; Jenkins, NA; Kalman, K; Mohrenweiser, H; Nguyen, A; Tseng-Crank, J | 1 |
1 review(s) available for cromakalim and nifedipine
| Article | Year |
|---|---|
[Analyses of Ca-related ion channel currents and their involvement in Ca mobilization in smooth muscle and endothelial cells].
Topics: Animals; Calcium; Calcium Channels; Chloride Channels; Cromakalim; Endothelium; Humans; Lysophospholipids; Membrane Potentials; Muscle, Smooth; Nifedipine; Palmitoylcarnitine; Potassium Channels; Sphingosine | 2003 |
94 other study(ies) available for cromakalim and nifedipine
| Article | Year |
|---|---|
Differential effects of nitrovasodilators, K(+)-channel openers, and nicorandil on large and small coronary arteries in conscious dogs.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Injections, Intravenous; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilation; Vasodilator Agents | 1992 |
Vasorelaxation of rat thoracic aorta caused by two Ca(2+)-channel blockers, HA-22 and HA-23.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Caffeine; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Nifedipine; Pyrans; Pyrazoles; Pyrroles; Rats; Rats, Inbred Strains; Vasodilation; Verapamil | 1992 |
Excitation-contraction coupling in canine tracheal smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Benzopyrans; Calcium; Calcium Channels; Cromakalim; Dogs; Egtazic Acid; In Vitro Techniques; Models, Biological; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympatholytics; Pyrroles; Sarcoplasmic Reticulum; Tetraethylammonium; Tetraethylammonium Compounds; Trachea | 1992 |
Characteristics of the contractile response of rabbit aorta produced by cromakalim in calcium-free solution.
Topics: Animals; Aorta; Benzopyrans; Calcium; Colforsin; Cromakalim; Guanidines; Male; Microelectrodes; Minoxidil; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Pinacidil; Potassium; Potassium Channels; Pyridines; Pyrroles; Rabbits; Vasoconstriction | 1992 |
Inhibitory effect of a novel antianginal agent, E4080, on ST segment elevation induced by vasopressin in anesthetized guinea pigs.
Topics: Anesthesia; Animals; Benzopyrans; Cardiovascular Agents; Catechols; Clonidine; Coronary Vessels; Cromakalim; Electrocardiography; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Isosorbide Dinitrate; Male; Nifedipine; Pyrroles; Vasodilator Agents; Vasopressins | 1992 |
Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Cromakalim; Dogs; Female; Heart Rate; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Prodrugs; Pyrroles; Rats; Rats, Inbred SHR; Tachycardia | 1992 |
The potassium channel opener BRL 38227 inhibits binding of [125I]-labelled endothelin-1 to rat cardiac membranes.
Topics: Animals; Benzopyrans; Binding, Competitive; Cromakalim; Endothelins; In Vitro Techniques; Ion Channel Gating; Myocardium; Nifedipine; Potassium Channels; Pyrroles; Rats; Sarcolemma | 1992 |
Existence of two components in the tonic contraction of rat aorta mediated by alpha 1-adrenoceptor activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Carbamates; Cromakalim; In Vitro Techniques; Isoquinolines; Lanthanum; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Phenylcarbamates; Phenylephrine; Phosphatidylinositols; Piperazines; Protease Inhibitors; Pyrroles; Rats | 1991 |
Characteristics of KRN2391, a novel vasodilator, compared with those of cromakalim, pinacidil and nifedipine in rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Guanylate Cyclase; Male; Muscle Relaxation; Nifedipine; Nitrogen Dioxide; Pinacidil; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Vasodilator Agents | 1991 |
Evaluation of the potassium channel activator BRL 38227 as an inhaled bronchodilator in the guinea-pig: contrast with nifedipine and salbutamol.
Topics: Administration, Inhalation; Airway Resistance; Albuterol; Aminophylline; Animals; Benzopyrans; Bronchoconstriction; Bronchodilator Agents; Cromakalim; Drug Evaluation, Preclinical; Guinea Pigs; Histamine; Lung; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Pyrroles | 1991 |
The diverse effects of cromakalim on tension and 86Rb efflux in canine arterial smooth muscle.
Topics: Animals; Arteries; Benzopyrans; Cromakalim; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Pyrroles; Rubidium Radioisotopes | 1991 |
RP 49356 and cromakalim relax airway smooth muscle in vitro by opening a sulphonylurea-sensitive K+ channel: a comparison with nifedipine.
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Glipizide; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Picolines; Potassium Channels; Pyrans; Pyrroles; Trachea | 1991 |
Differences between the effects of cromakalim and nifedipine on agonist-induced responses in rabbit aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Calcium; Cromakalim; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Norepinephrine; Potassium; Pyrroles; Rabbits; Vasodilation | 1991 |
Experimental hyperreflexia: effect of intravesical administration of various agents.
Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Diltiazem; Electric Stimulation; Electromyography; Hexamethonium Compounds; Male; Muscle Contraction; Nifedipine; Pyrroles; Rabbits; Reflex; Urinary Bladder Diseases; Vasodilator Agents; Verapamil | 1991 |
Evidence that pinacidil may promote the opening of ATP-sensitive K+ channels yet inhibit the opening of Ca2(+)-activated K+ channels in K(+)-contracted canine mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Dogs; Female; Glyburide; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Potassium; Potassium Channels; Pyrroles; Rubidium Radioisotopes | 1990 |
A comparison of the actions of cromakalim and nifedipine on rabbit isolated mesenteric artery.
Topics: Animals; Benzopyrans; Blood Pressure; Cell Membrane; Cromakalim; Electric Stimulation; Glyburide; Humans; In Vitro Techniques; Infant, Newborn; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Perfusion; Potassium Channels; Pyrroles; Rabbits | 1990 |
Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dogs; Female; Glyburide; Guanidines; Heart Atria; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1990 |
A comparison of the haemodynamic profiles of Ro 31-6930, cromakalim and nifedipine in anaesthetised normotensive rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Cromakalim; Heart Rate; Hemodynamics; Iliac Artery; Male; Nifedipine; Pyridines; Pyrroles; Rats; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vascular Resistance | 1990 |
Effects of cromakalim, a potassium channel opener, on regional blood flow in conscious spontaneously hypertensive rats.
Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Heart Rate; Hemodynamics; Humans; Hypertension; Infant, Newborn; Microspheres; Nifedipine; Pyrroles; Rats; Rats, Inbred SHR; Regional Blood Flow; Vascular Resistance | 1990 |
Inhibition by sulphonylureas of vasorelaxation induced by K+ channel activators in vitro.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Drug Interactions; Glipizide; Glyburide; Guanidines; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Pinacidil; Potassium Channels; Potassium Chloride; Pyrroles; Rabbits; Sulfonylurea Compounds; Tolbutamide; Vasodilator Agents | 1989 |
Effect of cromakalim on contractions in rabbit isolated renal artery in the presence and absence of extracellular Ca2+.
Topics: Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Cromakalim; Guanidines; Guanylate Cyclase; Histamine; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Norepinephrine; Pinacidil; Pyrroles; Rabbits; Renal Artery; Vasodilator Agents | 1989 |
Haemodynamic differences between cromakalim and pinacidil: comparison with nifedipine.
Topics: Animals; Benzopyrans; Blood Pressure; Cats; Cromakalim; Guanidines; Heart Rate; Hemodynamics; Male; Nifedipine; Pinacidil; Pyrroles; Renal Circulation; Renin | 1989 |
BRL 34915 (Cromakalim) stimulation of 42K efflux from rabbit arteries is modulated by calcium.
Topics: Animals; Antihypertensive Agents; Arteries; Benzopyrans; Calcium; Cromakalim; Dose-Response Relationship, Drug; Male; Nifedipine; Nisoldipine; Norepinephrine; Potassium; Potassium Channels; Pyrroles; Rabbits; Tetraethylammonium Compounds; Vasoconstriction | 1989 |
Comparison of the effects of RP 49356, cromakalim and nifedipine on guinea-pig trachea in vitro.
Topics: Animals; Benzopyrans; Cromakalim; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Nifedipine; Picolines; Potassium Channels; Pyrans; Pyrroles; Trachea | 1989 |
The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
Increased vasodilator responsiveness to BRL 34915 in spontaneously hypertensive versus normotensive rats: contrast with nifedipine.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilation | 1989 |
Anti-spasmogenic and spasmolytic effects of BRL 34915: a comparison with nifedipine and nicorandil.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Norepinephrine; Parasympatholytics; Potassium Chloride; Pyrroles; Rabbits | 1987 |
Potassium efflux enhancement by cromakalim (BRL 34915) in rabbit mesenteric artery: an indirect effect independent of calcium?
Topics: Animals; Benzopyrans; Buffers; Calcium; Cromakalim; In Vitro Techniques; Lanthanum; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Pyrroles; Rabbits; Rubidium | 1988 |
Evaluation of the potassium channel activator cromakalim (BRL 34915) as a bronchodilator in the guinea-pig: comparison with nifedipine.
Topics: Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Guinea Pigs; Histamine; In Vitro Techniques; Male; Nifedipine; Ovalbumin; Potassium Channels; Pyrroles; Serotonin Antagonists; Trachea | 1988 |
Similarity of relaxations evoked by BRL 34915, pinacidil and field-stimulation in rat oesophageal tunica muscularis mucosae.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Electric Stimulation; Esophagus; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Rats; Rubidium Radioisotopes; Tetrodotoxin | 1988 |
Studies on the anti-vasoconstrictor activity of BRL 34915 in spontaneously hypertensive rats; a comparison with nifedipine.
Topics: Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Female; Hypertension; Infusions, Intravenous; Nifedipine; Norepinephrine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vasoconstriction; Vasopressins | 1988 |
Effects of KRN4884, a novel K channel opener, on the cardiovascular system in anesthetized dogs: a comparison with levcromakalim, nilvadipine, and nifedipine.
Topics: Anesthesia; Animals; Antihypertensive Agents; Aorta; Benzopyrans; Calcium Channel Blockers; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Nifedipine; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 1995 |
Modulators of calcium and potassium channels: their effects on endothelin-1 binding to cardiac membranes.
Topics: Animals; Benzopyrans; Calcium Channels; Cromakalim; Dihydropyridines; Endothelins; Heart; In Vitro Techniques; Male; Membranes; Myocardium; Nifedipine; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley | 1993 |
Pharmacologic profiles of YM934, a novel potassium channel opener.
Topics: Anesthesia; Animals; Aorta; Benzopyrans; Benzoxazines; Cromakalim; Cyclic N-Oxides; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Oxazines; Portal Vein; Potassium Channels; Pyrroles; Rabbits; Rats; Rats, Wistar; Vascular Resistance; Vasodilation | 1994 |
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
Topics: 3T3 Cells; Animals; Base Sequence; Benzopyrans; Capsaicin; Cell Line; Cells, Cultured; Charybdotoxin; Cloning, Molecular; Cromakalim; Diltiazem; Diterpenes; Elapid Venoms; Flecainide; Ion Channel Gating; Mice; Molecular Sequence Data; Nifedipine; Oligodeoxyribonucleotides; Peptides; Potassium Channels; Pyrroles; Scorpion Venoms; Sotalol | 1994 |
Propagation of impulses in the guinea-pig ureter and its blockade by calcitonin gene-related peptide (CGRP).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Cromakalim; Electric Stimulation; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyrroles; Tetrodotoxin; Ureter | 1995 |
Response of guinea pig smooth and striated urethral sphincter to cromakalim, prazosin, nifedipine, nitroprusside, and electrical stimulation.
Topics: Amino Acid Oxidoreductases; Animals; Antihypertensive Agents; Benzopyrans; Calcium; Calmodulin-Binding Proteins; Cromakalim; Decamethonium Compounds; Electric Stimulation; Guinea Pigs; Hexamethonium; Histocytochemistry; Male; Muscle Contraction; Muscle Relaxation; Muscle, Skeletal; Muscle, Smooth; Nifedipine; Nitric Oxide Synthase; Nitroprusside; Prazosin; Pyrroles; Urethra | 1995 |
Pharmacological natures of caffeine-induced endothelium-dependent and -independent contraction in canine mesenteric artery.
Topics: Adenylyl Cyclases; Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Colforsin; Cromakalim; Dogs; Edetic Acid; Egtazic Acid; Endothelium, Vascular; Female; In Vitro Techniques; Magnesium; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Functional study on the effects of nifedipine, cromakalim, and the absence of extracellular Ca2+ on alpha 1-adrenoceptor-mediated excitation-contraction coupling in isolated rat portal vein: comparison with depolarization-mediated excitation-contraction c
Topics: Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Parasympatholytics; Phenylephrine; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1993 |
Distinct pathways to refill ACh-sensitive internal Ca2+ stores in canine airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Benzopyrans; Calcium; Cromakalim; Dogs; Female; Indoles; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyrroles; Trachea | 1993 |
Effect of KRN2391 on venous return: comparison with other vasodilators.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyridines; Pyrroles; Vasodilator Agents; Veins | 1993 |
A simple method for measurement of ureteric peristaltic function in vivo and the effects of drugs acting on ion channels applied from the ureter lumen in anesthetized rats.
Topics: 4-Aminopyridine; Anesthesia; Animals; Benzopyrans; Cromakalim; Glyburide; Ion Channels; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyrroles; Rats; Rats, Sprague-Dawley; Ureter; Vasodilator Agents | 1993 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glyburide; Histamine; Hypertension; Male; Mesenteric Arteries; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents | 1994 |
Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries.
Topics: Aged; Animals; Benzopyrans; Calcium; Calcium Channels; Cromakalim; Glyburide; Humans; Hypoxia; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Male; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Vasoconstriction; Verapamil | 1995 |
Potassium channel openers relax A23187-induced nifedipine-resistant contraction of rat aorta.
Topics: Animals; Aorta; Benzopyrans; Calcimycin; Cromakalim; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Oxadiazoles; Piperidines; Pyrroles; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1994 |
Pharmacological analysis of the effect of KRN2391 on coronary vasculature in perfused rat heart.
Topics: Animals; Benzopyrans; Coronary Circulation; Cromakalim; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Male; Nifedipine; Perfusion; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Wistar; Vasodilator Agents | 1994 |
Differential vasodilator properties of KRN2391, cromakalim, nitroglycerin and nifedipine in rabbit isolated femoral artery and vein.
Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Femoral Artery; Femoral Vein; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Pyridines; Pyrroles; Rabbits; Vasodilation; Vasodilator Agents | 1994 |
Levcromakalim-induced modulation of membrane potassium currents, intracellular calcium and mechanical activity in rat mesenteric artery.
Topics: Animals; Arterioles; Benzopyrans; Calcium; Cell Membrane; Cromakalim; Electrophysiology; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1994 |
Characteristics of early afterdepolarization in mouse atrial fibers.
Topics: Aconitine; Action Potentials; Animals; Atrial Function; Benzopyrans; Cromakalim; Electrophysiology; Female; Heart; Male; Mice; Nifedipine; Pyrroles; Quinidine; Ryanodine; Tetrodotoxin | 1994 |
Effects of levcromakalim on ureteral peristaltic function and cystometrogram in rats.
Topics: Administration, Topical; Animals; Benzopyrans; Cromakalim; Glyburide; Injections, Intraperitoneal; Injections, Intravenous; Male; Nifedipine; Parasympatholytics; Pyrroles; Rats; Rats, Sprague-Dawley; Ureter; Urinary Bladder | 1993 |
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents | 1993 |
Lemakalim attenuates hypocapnia- and dry air-induced bronchoconstriction in canine peripheral airways.
Topics: Acetylcholine; Adenosine Triphosphate; Aerosols; Airway Resistance; Albuterol; Animals; Benzopyrans; Blood Pressure; Bronchoconstriction; Bronchodilator Agents; Cromakalim; Dogs; Glyburide; Heart Rate; Humidity; Hypocapnia; Injections, Intravenous; Lung; Male; Nifedipine; Potassium Channels; Pyrroles | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents | 1993 |
The effect of cromakalim on the electrical properties of and [86Rb+] efflux from normal and hypertrophied rat bladder.
Topics: Action Potentials; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Female; Hypertrophy; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympatholytics; Pyrroles; Rats; Rats, Sprague-Dawley; Rubidium; Rubidium Radioisotopes; Urinary Bladder | 1993 |
Effects of a K+ATP channel opener, lemakalim, on systemic, coronary and regional vascular dynamics in conscious dogs: comparison with nifedipine, adenosine, nitroglycerin and acetylcholine.
Topics: Acetylcholine; Adenosine; Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Hemodynamics; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Regional Blood Flow; Vascular Resistance; Vasodilator Agents | 1993 |
Effects of potassium channel openers in isolated human cerebral arteries.
Topics: Benzopyrans; Calcium Channel Blockers; Carbachol; Cerebral Arteries; Cromakalim; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanidines; Humans; Iloprost; Nifedipine; Nimodipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Differential vasorelaxant effects of levcromakalim and P1060 in the isolated KCl- and RbCl-precontracted human saphenous vein: possible involvement of intracellular Ca2+ stores.
Topics: Benzopyrans; Caffeine; Calcium; Chlorides; Cromakalim; Guanidines; Humans; In Vitro Techniques; Nifedipine; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Rubidium; Saphenous Vein; Vasodilator Agents | 1995 |
Cellular localization of the inhibitory action of relaxin against uterine spasm.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Benzopyrans; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Membrane; Cromakalim; Female; Nifedipine; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Relaxin; Spasm; Uterine Diseases | 1995 |
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Methacholine Chloride; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroprusside; Norepinephrine; Obesity; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Zucker; Serotonin; Tunica Media; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Possible mechanism of the potent vasoconstrictor responses to ryanodine in dog cerebral arteries.
Topics: Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Cerebral Arteries; Cromakalim; Dogs; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Potassium; Pyrroles; Ryanodine; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Effects of the potassium channel openers KRN4884 and levcromakalim on the contraction of rat aorta induced by A23187, compared with nifedipine.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Calcimycin; Calcium; Calcium Channel Blockers; Cromakalim; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Wistar; Vasodilator Agents | 1996 |
Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
The role of a cAMP-dependent pathway in the uterine relaxant action of relaxin in rats.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Cyclic AMP-Dependent Protein Kinases; Female; In Vitro Techniques; Isoquinolines; Myometrium; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Relaxin; Signal Transduction; Uterine Contraction; Uterus | 1997 |
KRN4884, a novel K channel opener: antihypertensive effects in conscious renal hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Calcium Channel Blockers; Cromakalim; Dogs; Female; Hypertension, Renal; Male; Nifedipine; Potassium Channels; Pyridines; Pyrroles | 1997 |
Effects of cGMP and the nitric oxide donors glyceryl trinitrate and sodium nitroprusside on contractions in vitro of isolated myometrial tissue from pregnant women.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Benzopyrans; Calcium Channel Agonists; Calcium Channel Blockers; Cromakalim; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Myometrium; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Pregnancy; Pyrroles; Uterine Contraction; Vasodilator Agents; Verapamil | 1997 |
Mediation of neuronal apoptosis by enhancement of outward potassium current.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzopyrans; Calcium; Cerebral Cortex; Cromakalim; Cycloheximide; Cysteine Proteinase Inhibitors; Gadolinium; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Channels; Pyrroles; Staurosporine; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine | 1997 |
Effect of cromakalim on the purinergic and cholinergic transmission in the rat detrusor muscle.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cromakalim; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth; Nifedipine; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Purinergic; Urinary Bladder | 1997 |
Effect of JTV-506, a novel vasodilator, on experimental angina model in rats.
Topics: Administration, Oral; Angina Pectoris; Animals; Arginine Vasopressin; Blood Pressure; Chromans; Cromakalim; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Injections, Intravenous; Male; Methacholine Chloride; Molecular Structure; Niacinamide; Nicorandil; Nifedipine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
The effects of nifedipine and other calcium antagonists on the glibenclamide-sensitive K+ currents in smooth muscle cells from pig urethra.
Topics: Animals; Barium; Calcium Channel Blockers; Cromakalim; Female; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Muscle, Smooth; Nifedipine; Patch-Clamp Techniques; Potassium Channels; Swine; Urethra | 1998 |
Effect of calcium antagonists on the response to noradrenaline in the whole and bisected rat vas deferens.
Topics: Animals; Calcium Channel Blockers; Cromakalim; Diltiazem; Flunarizine; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Organ Culture Techniques; Papaverine; Rats; Rats, Wistar; Vas Deferens | 1998 |
Effects of KRN4884 (a novel K+ channel opener), levcromakalim, nilvadipine and propranolol on endothelin-1-induced heart disorders in anesthetized rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Bronchoconstrictor Agents; Cromakalim; Electrocardiography; Endothelin-1; Heart Diseases; Heart Rate; Injections, Intra-Arterial; Male; Methacholine Chloride; Nifedipine; Potassium Channels; Propranolol; Pyridines; Rats; Rats, Wistar | 1998 |
Voltage sensitivity of slow wave frequency in isolated circular muscle strips from guinea pig gastric antrum.
Topics: Animals; Calcium Channel Blockers; Cations; Cromakalim; Electrophysiology; Extracellular Space; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Muscle, Smooth; Nickel; Nifedipine; Potassium; Pyloric Antrum; Tetrodotoxin | 1999 |
Antihypertensive properties of KRN4884, a novel long-lasting potassium channel opener.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Cromakalim; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; Nifedipine; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Time Factors; Vasodilation | 1999 |
The ginsenoside Rg3 evokes endothelium-independent relaxation in rat aortic rings: role of K+ channels.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; Ginsenosides; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Nifedipine; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Saponins; Tetraethylammonium; Vasodilator Agents | 1999 |
Effects of the new potassium channel opener JTV-506 on coronary vessels in vitro and in vivo.
Topics: Anesthesia; Animals; Chromans; Coronary Circulation; Coronary Vessels; Cromakalim; Dogs; Female; In Vitro Techniques; Male; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Swine; Vasodilator Agents | 1999 |
Depolarization of membrane potential and the smooth muscle contraction by isothiocyanatobenzyl imidazoline in guinea-pig stomach circular muscle.
Topics: Animals; Atropine; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Oxymetazoline; Stomach; Tolazoline; Vasodilator Agents | 1999 |
Effects of K(+) channel inhibitors on relaxation induced by flufenamic and tolfenamic acids in guinea-pig trachea.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium Channels, L-Type; Cromakalim; Dinoprost; Female; Flufenamic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Nifedipine; ortho-Aminobenzoates; Potassium Channel Blockers; Potassium Channels; Trachea | 1999 |
Differential blockade of alpha,beta-methylene-ATP, noradrenaline and electrically evoked contractions of the rat vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Clonidine; Cromakalim; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Papaverine; Rats; Rats, Wistar; Vas Deferens; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 1999 |
Selective inhibitory effects of niflumic acid on 5-HT-induced contraction of the rat isolated stomach fundus.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chloride Channels; Cromakalim; Diphenylamine; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Niflumic Acid; Potassium Chloride; Rats; Rats, Wistar; Serotonin; Vasodilator Agents | 2000 |
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle.
Topics: Acetylcholine; Animals; Calcium; Cattle; Cromakalim; Diamines; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical; Tetraethylammonium; Trachea | 2000 |
[Effects of nifedipine and cromakalim on isolated rat bladder tissue and aorta strip].
Topics: Animals; Aorta; Calcium Channel Blockers; Cromakalim; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Wistar; Urinary Bladder | 1997 |
Effect of 17beta-estradiol exposure on vasorelaxation induced by K(+) channel openers and Ca(2+) channel blockers.
Topics: Animals; Calcium Channel Blockers; Cromakalim; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; In Vitro Techniques; Male; Mesenteric Arteries; Nifedipine; Pinacidil; Potassium Channels; Progesterone; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents; Verapamil | 2002 |
Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; Charybdotoxin; Colforsin; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Fura-2; Guinea Pigs; Isotonic Contraction; Male; Mechanotransduction, Cellular; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Transducers; Urinary Bladder | 2004 |
[High throughput screening method of potassium channel regulators].
Topics: 4-Aminopyridine; Animals; Barbiturates; Calcium Channel Blockers; Cromakalim; Isoxazoles; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Quinidine; Rats | 2004 |
Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells.
Topics: Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Capillaries; Cromakalim; Endothelial Cells; Endothelium, Vascular; Ion Channel Gating; Ion Transport; Lung; Membrane Potentials; Mibefradil; Nifedipine; Potassium Channel Blockers; Potassium Channels; Rats; Reverse Transcriptase Polymerase Chain Reaction; Rheology; RNA, Messenger | 2004 |
Vasorelaxant effect of levcromakalim on isolated umbilical arteries of preeclamptic women.
Topics: Adult; Case-Control Studies; Cromakalim; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Magnesium Sulfate; Muscle, Smooth, Vascular; Nifedipine; Pre-Eclampsia; Pregnancy; Umbilical Arteries; Vasodilation; Vasodilator Agents | 2007 |
Store-refilling involves both L-type calcium channels and reverse-mode sodium-calcium exchange in airway smooth muscle.
Topics: Acetylcholine; Analysis of Variance; Animals; Blotting, Western; Calcium Channels, L-Type; Calcium Signaling; Cattle; Cromakalim; Muscle Contraction; Muscle, Smooth; Nifedipine; Sodium-Calcium Exchanger; Thiourea; Trachea | 2007 |
K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.
Topics: 4-Aminopyridine; Arachidonic Acids; Barium Compounds; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Chlorides; Chorionic Gonadotropin; Cromakalim; Endocannabinoids; Female; Giant Cells; Humans; L-Lactate Dehydrogenase; Nifedipine; Pinacidil; Placenta; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Channels; Pregnancy; Tetraethylammonium; Trophoblasts | 2008 |
The effect of progesterone on myometrial contractility, potassium channels, and tocolytic efficacy.
Topics: Adult; Analysis of Variance; Cesarean Section; Cromakalim; Dose-Response Relationship, Drug; Female; Humans; Myometrium; Nifedipine; Oxytocin; Potassium Channel Blockers; Potassium Channels; Progesterone; Progestins; Ritodrine; Tocolytic Agents; Uterine Contraction | 2009 |
Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
Topics: Aldosterone; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Canrenoic Acid; Cromakalim; Female; KATP Channels; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Channels, Calcium-Activated; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilator Agents | 2012 |
Significance of K(ATP) channels, L-type Ca²⁺ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles in vivo.
Topics: Animals; Arterioles; Calcium Channels, L-Type; Cromakalim; Cytochrome P-450 Enzyme System; Glyburide; Hydroxyeicosatetraenoic Acids; KATP Channels; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide Synthase; Oxygen; Retinoic Acid 4-Hydroxylase; Vasoconstriction; Vasodilation | 2013 |
Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis.
Topics: Amides; Animals; Benzopyrans; Bronchodilator Agents; Chemical Phenomena; Chemistry; Cromakalim; Guinea Pigs; Molecular Structure; Muscle Relaxation; Potassium Channels; Pyrroles; Structure-Activity Relationship; Trachea | 1990 |
Synthesis and antihypertensive activity of 4-(cyclic amido)-2H-1-benzopyrans.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1986 |
Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Chromosomes; Cloning, Molecular; Electrophysiology; Humans; In Situ Hybridization; Ion Channel Gating; Islets of Langerhans; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neurotoxins; Phylogeny; Potassium Channels; Sequence Analysis, DNA; Shaker Superfamily of Potassium Channels | 1998 |