cromakalim has been researched along with n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atwal, KS; Bryson, CC; Cohen, RB; Dickinson, KE; Grover, GJ; Lodge, NJ; Normandin, DE; Sleph, PG; Traeger, SC | 1 |
| Altenbach, RJ; Bai, H; Brioni, JD; Brune, ME; Buckner, SA; Carroll, WA; Cassidy, C; Chen, Y; Coghlan, MJ; Daza, AV; Drizin, I; Fey, TA; Fitzgerald, M; Gopalakrishnan, M; Gregg, RJ; Henry, RF; Holladay, MW; King, LL; Kort, ME; Kym, PR; Milicic, I; Sullivan, JP; Tang, R; Turner, SC; Whiteaker, KL; Yi, L; Zhang, H | 1 |
| Altenbach, RJ; Brune, ME; Buckner, SA; Carroll, WA; Coghlan, MJ; Daza, AV; Fabiyi, A; Gopalakrishnan, M; Henry, RF; Khilevich, A; Kort, ME; Milicic, I; Scott, VE; Smith, JC; Whiteaker, KL | 1 |
| Brown, FJ; Empfield, J; Li, JH; McConville, M; Ohnmacht, CJ; Potter-Lee, L; Russell, K; Stetz, SL; Trainor, DA; Trivedi, S | 1 |
| Kau, S; Levin, R; Li, J; Stetz, S; Trivedi, S | 1 |
| Sargent, C; Smith, MA; Weselcouch, EO; Wilde, MW | 1 |
| Quast, U; Villhauer, EB | 1 |
| Hambrock, A; Kickenweiz, E; Krippeit-Drews, P; Metzger, F; Quast, U; Russ, U | 1 |
| Bell, KL; Favaloro, JL; Kubo, M; McPherson, GA; Standen, NB | 1 |
| Bell, K; Favaloro, J; Iskander, MM; Khalil, V; McPherson, GA | 1 |
| Buckner, SA; Carroll, WA; Drizin, I; Gopalakrishnan, M; Gopalakrishnan, S; Holladay, MW; Sullivan, JP; Whiteaker, KL; Yi, L; Zhang, HQ | 1 |
| Brune, ME; Buckner, SA; Coghlan, M; Daza, A; Fey, TA; Gopalakrishnan, M; Milicic, I | 1 |
| Baun, M; Boni, LJ; Hay-Schmidt, A; Jansen-Olesen, I; Olesen, J; Ploug, KB | 1 |
| Gaisano, HY; Kang, Y; Ng, B; Sun, H; Xie, H | 1 |
| Andres, H; Bray, K; Manley, PW; Quast, U | 1 |
| Atwal, KS; Ferrara, FN; Green, DW; Grover, GJ; Monshizadegan, H; Rogers, WL; Sleph, P; Traeger, S; Wang, P | 1 |
| Bhattacharjee, S; Kraft, P; Li, X; Lundeen, SG; Qiu, Y; Sui, Z; Woods, M; Zhang, X | 1 |
| Balsamo, A; Bianucci, AM; Calderone, V; Coi, A; Digiacomo, M; Rapposelli, S; Testai, L | 1 |
18 other study(ies) available for cromakalim and n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine
| Article | Year |
|---|---|
Binding of ATP-sensitive potassium channel (KATP) openers to cardiac membranes: correlation of binding affinities with cardioprotective and smooth muscle relaxing potencies.
Topics: Animals; ATP-Binding Cassette Transporters; Cardiotonic Agents; Dogs; KATP Channels; Muscle Relaxation; Muscle, Smooth; Myocardium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Structure-Activity Relationship | 1998 |
Synthesis and structure-activity relationships of a novel series of 2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide K(ATP) channel openers: discovery of (-)-(9S)-9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-b]quinolin-8(4H)
Topics: Adenosine Triphosphate; Animals; Cyclic S-Oxides; Electric Stimulation; Guinea Pigs; Hemodynamics; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Potassium Channels; Quinolones; Stereoisomerism; Structure-Activity Relationship; Swine; Urinary Bladder; Urodynamics | 2004 |
Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium channel opener.
Topics: Adenosine Triphosphate; Animals; Aza Compounds; Cell Line; Crystallography, X-Ray; Dihydropyridines; Electric Stimulation; Heterocyclic Compounds, 3-Ring; In Vitro Techniques; Ion Channel Gating; Mice; Muscle Contraction; Muscle, Smooth; Naphthalenes; Potassium Channels, Inwardly Rectifying; Stereoisomerism; Structure-Activity Relationship; Swine; Urinary Bladder | 2006 |
K-channel opening activity of ZD6169 and its analogs: effect on 86Rb efflux and 3H-P1075 binding in bladder smooth muscle.
Topics: Amides; Animals; Benzophenones; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Kinetics; Muscle, Smooth; Potassium Channels; Pyridines; Pyrroles; Rubidium; Urinary Bladder; Vasodilator Agents | 1995 |
Effect of cromakalim and pinacidil on 86Rb efflux from guinea pig urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Male; Membrane Potentials; Muscle, Smooth; Pinacidil; Potassium Channels; Pyridines; Pyrroles; Rubidium Radioisotopes; Stereoisomerism; Urinary Bladder; Vasodilator Agents | 1994 |
ATP-sensitive potassium channels and skeletal muscle function in vitro.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; Energy Metabolism; Gallamine Triethiodide; Glyburide; Guanidines; In Vitro Techniques; Ischemia; Male; Muscle Contraction; Muscles; Pinacidil; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley | 1993 |
The individual enantiomers of cis-cromakalim possess K+ channel opening activity.
Topics: Anesthesia; Animals; Aorta, Thoracic; Benzopyrans; Binding, Competitive; Blood Pressure; Cromakalim; Endothelium, Vascular; Guanidines; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Wistar; Rubidium Radioisotopes; Stereoisomerism; Vasodilation; Vasodilator Agents | 1993 |
Binding and effects of KATP channel openers in the vascular smooth muscle cell line, A10.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Cell Line; Cromakalim; Glyburide; Guanidines; Membrane Potentials; Minoxidil; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Pinacidil; Potassium Channel Blockers; Potassium Channels; Pyridines; Radioligand Assay; Rats; Vasodilator Agents | 1997 |
Functional and electrophysiological effects of a novel imidazoline-based K(ATP) channel blocker, IMID-4F.
Topics: Aniline Compounds; Animals; Arteries; Cattle; Cromakalim; Guanidines; Imidazoles; Membrane Potentials; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Pyridines; Rats; Rats, Inbred WKY; Swine; Vasodilation; Vasodilator Agents | 1999 |
The identification of a potent imidazoline-based vascular K(ATP) channel antagonist.
Topics: Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Cattle; Clonidine; Coronary Vessels; Cromakalim; Glyburide; Guanidines; Heart Atria; Heart Rate; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; KATP Channels; Muscle, Smooth, Vascular; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Radioligand Assay; Rats; Swine; Vasodilator Agents | 2000 |
Structure-Activity studies for a novel series of tricyclic dihydropyrimidines as K(ATP) channel openers (KCOs).
Topics: Animals; Cell Culture Techniques; Cromakalim; Fluorescence; Guanidines; Guinea Pigs; Heterocyclic Compounds, 3-Ring; Membrane Potentials; Potassium Channels; Pyridines; Pyrimidines; Structure-Activity Relationship; Urinary Bladder | 2002 |
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Carbachol; Cholinergic Agonists; Cromakalim; Cyclic S-Oxides; Diazoxide; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanidines; Histamine; Hypertrophy; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Chloride; Pyridines; Quinolones; Serotonin; Serotonin Agents; Swine; Urinary Bladder; Urinary Bladder Neck Obstruction; Vasodilator Agents | 2006 |
K(ATP) channel expression and pharmacological in vivo and in vitro studies of the K(ATP) channel blocker PNU-37883A in rat middle meningeal arteries.
Topics: Adamantane; Animals; ATP-Binding Cassette Transporters; Blotting, Western; Cromakalim; Data Interpretation, Statistical; Diuretics; Guanidines; In Vitro Techniques; KATP Channels; Male; Meningeal Arteries; Microscopy, Video; Morpholines; Multidrug Resistance-Associated Proteins; Pinacidil; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonylurea Receptors; Vasodilator Agents | 2008 |
Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel.
Topics: Animals; Cell Line; Cells, Cultured; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Guanidines; Humans; KATP Channels; Kidney; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyridines; Syntaxin 1; Vasodilator Agents | 2008 |
Synthesis of and radioligand binding studies with a tritiated pinacidil analogue: receptor interactions of structurally different classes of potassium channel openers and blockers.
Topics: Animals; Binding Sites; Drug Interactions; Guanidines; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Pyridines; Rats; Structure-Activity Relationship; Vasodilator Agents | 1993 |
Small molecule mitochondrial F1F0 ATPase hydrolase inhibitors as cardioprotective agents. Identification of 4-(N-arylimidazole)-substituted benzopyran derivatives as selective hydrolase inhibitors.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cardiotonic Agents; Cattle; Citrate (si)-Synthase; Electron Transport Complex IV; Hydrolysis; Imidazoles; In Vitro Techniques; Mitochondrial Proton-Translocating ATPases; Myocardial Contraction; Rats; Stereoisomerism; Structure-Activity Relationship | 2004 |
Discovery and structure-activity relationships of a novel series of benzopyran-based K(ATP) openers for urge urinary incontinence.
Topics: Animals; Benzopyrans; Disease Models, Animal; Potassium Channels, Inwardly Rectifying; Rats; Structure-Activity Relationship; Urinary Bladder; Urinary Incontinence, Urge | 2009 |
Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers.
Topics: Algorithms; Benzopyrans; Cardiotonic Agents; KATP Channels; Models, Chemical; Molecular Structure; Quantitative Structure-Activity Relationship; Spiro Compounds | 2009 |