cromakalim has been researched along with morphine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Funada, M; Kamei, J; Kawashima, N; Misawa, M; Nagase, H; Narita, M; Suzuki, T; Takamori, K | 1 |
| Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Narita, M; Suzuki, T | 1 |
| Baeyens, JM; Barrios, M; Robles, LI | 1 |
| Arletti, R; Benelli, A; Bertolini, A; Cavazzuti, E; Poggioli, R | 1 |
| Baeyens, JM; Barrios, M; Ocaña, M | 1 |
| Lohmann, AB; Welch, SP | 2 |
| Asano, T; Dohi, S; Iida, H | 1 |
| Chen, JY; Dafny, N; Kang, YM; Ouyang, W; Qiao, JT | 1 |
| Sharma, A; Singh, M; Sood, V | 1 |
| Asadi, S; Dehpour, AR; Ebrahimi, F; Ghasemi, M; Hajrasouliha, AR; Sadeghipour, H; Shafaroodi, H; Tavakoli, S | 1 |
| Garg, GR; Halder, S; Khanna, N; Malhotra, RS; Mehta, AK; Sharma, KK | 2 |
| Cao, Z; Chen, L; Chiang, LY; Dai, W; Hu, L; Liu, W; Yang, X; Zhang, R | 1 |
| Amiri, S; Dehdashtian, A; Dehpour, AR; Ghasemi, M; Ostadhadi, S; Sheikhi, M; Shirzadian, A | 1 |
15 other study(ies) available for cromakalim and morphine
| Article | Year |
|---|---|
Activation of central ATP-sensitive potassium channels produces the antinociception and spinal noradrenaline turnover-enhancing effect in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine Triphosphate; Analgesics; Animals; Benzopyrans; Cromakalim; Glyburide; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Morphine; Norepinephrine; Parasympatholytics; Potassium Channels; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Spinal Cord; Stimulation, Chemical | 1993 |
Reduction in ATP-sensitive potassium channel-mediated antinociception in diabetic mice.
Topics: Adenosine Triphosphate; Analgesics; Animals; Benzopyrans; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glyburide; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Potassium Channels; Pyrroles; Receptors, Opioid, mu; Tetraethylammonium Compounds | 1994 |
ATP-sensitive K+ channel openers inhibit morphine withdrawal.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Benzopyrans; Body Weight; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Morphine; Naloxone; Potassium Channels; Pyrroles; Substance Withdrawal Syndrome | 1994 |
K+ channel openers delay intestinal transit and have antidiarrheal activity.
Topics: Animals; Benzopyrans; Cromakalim; Diarrhea; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guanidines; Male; Mice; Mice, Inbred Strains; Morphine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Cromakalim differentially enhances antinociception induced by agonists of alpha(2)adrenoceptors, gamma-aminobutyric acid(B), mu and kappa opioid receptors.
Topics: Animals; Baclofen; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Morphine; Nociceptors; Pain; Pyrroles; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vasodilator Agents | 1996 |
ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine Triphosphate; Analgesics; Animals; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Glyburide; Injections, Intraventricular; Ion Channel Gating; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Potassium Channels; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin | 1999 |
Antisenses to opioid receptors attenuate ATP-gated K(+) channel opener-induced antinociception.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine Triphosphate; Analgesia; Analgesics; Animals; Cromakalim; Diazoxide; Enkephalin, D-Penicillamine (2,5)-; Male; Mice; Mice, Inbred ICR; Morphine; Nociceptors; Oligodeoxyribonucleotides, Antisense; Pain; Potassium Channels; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1999 |
Antinociceptive action of epidural K+(ATP) channel openers via interaction with morphine and an alpha(2)- adrenergic agonist in rats.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Analgesia; Analgesics, Opioid; Anesthetics, Combined; Animals; Cromakalim; Dexmedetomidine; Drug Interactions; Drug Synergism; Glyburide; Injections, Epidural; Ion Channel Gating; Male; Morphine; Naloxone; Narcotic Antagonists; Nicorandil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 2000 |
Norepinephrine modulates single hypothalamic arcuate neurons via alpha(1)and beta adrenergic receptors.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Cromakalim; Female; Glyburide; In Vitro Techniques; Locus Coeruleus; Magnesium; Male; Morphine; Naloxone; Neural Inhibition; Neural Pathways; Neurons; Norepinephrine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Yohimbine | 2000 |
Role of KATP channels in reduced antinociceptive effect of morphine in streptozotocin-induced diabetic mice.
Topics: Adenosine Triphosphate; Analgesics; Animals; Cromakalim; Diabetes Mellitus, Experimental; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Potassium Channels; Spleen | 2000 |
Role of ATP-sensitive potassium channels in the biphasic effects of morphine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Blood Glucose; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Glyburide; Hypoglycemic Agents; Male; Mice; Morphine; Narcotics; Pentylenetetrazole; Potassium Channels; Seizures; Severity of Illness Index | 2007 |
Interaction of morphine and potassium channel openers on experimental models of pain in mice.
Topics: Animals; Calcium Channel Agonists; Cromakalim; Diazoxide; Drug Interactions; Drug Therapy, Combination; Female; Glyburide; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Minoxidil; Morphine; Naloxone; Pain; Pain Measurement; Potassium Channels | 2011 |
Potassium channel openers exhibit cross-tolerance with morphine in two experimental models of pain.
Topics: Analgesics, Opioid; Animals; Cromakalim; Diazoxide; Drug Tolerance; Ion Channel Gating; Mice; Minoxidil; Models, Animal; Morphine; Pain; Potassium Channels | 2010 |
Opening of the Adenosine Triphosphate-sensitive Potassium Channel Attenuates Morphine Tolerance by Inhibiting JNK and Astrocyte Activation in the Spinal Cord.
Topics: Analgesics, Opioid; Animals; Astrocytes; Cromakalim; Dose-Response Relationship, Drug; Drug Tolerance; GABA Modulators; Interleukin-1beta; KATP Channels; Male; MAP Kinase Kinase 4; Membrane Transport Modulators; Mice; Morphine; Nociception; Pain Threshold; Pentobarbital; Spinal Cord | 2016 |
Involvement of ATP-sensitive potassium channels and the opioid system in the anticonvulsive effect of zolpidem in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Cromakalim; Dose-Response Relationship, Drug; Drug Therapy, Combination; gamma-Aminobutyric Acid; KATP Channels; Male; Mice; Morphine; Pentylenetetrazole; Pyridines; Seizures; Zolpidem | 2016 |