cromakalim has been researched along with cyclic gmp in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.89) | 18.7374 |
| 1990's | 36 (80.00) | 18.2507 |
| 2000's | 4 (8.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Holzmann, S; Kukovetz, WR; Pöch, G | 1 |
| Adams, D; Arch, JR; Challiss, RA; Patel, N | 1 |
| Hong, KW; Kim, CD; Lee, WS; Rhim, BY | 1 |
| Braida, C; Holzmann, S; Kukovetz, WR; Pöch, G | 1 |
| Shikada, K; Tanaka, S | 1 |
| Huang, LJ; Huang, TF; Kuo, SC; Sun, SS; Teng, CM; Yu, SM | 1 |
| Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM | 1 |
| Bray, KM; Brown, BS; Duty, S; Edwards, G; Kay, PB; Longmore, J; McHarg, AD; Newgreen, DT; Southerton, JS; Weston, AH | 1 |
| Kaneko, K; Miyata, N; Otomo, S; Tanaka, M; Tsuchida, K | 1 |
| Coldwell, MC; Howlett, DR | 1 |
| Baker, JR; Southerton, JS; Taylor, SG; Weston, AH | 1 |
| Gillespie, JS; Sheng, H | 1 |
| Hashimoto, H; Taira, N; Yanagisawa, T | 1 |
| Satake, N; Shibata, S; Zhou, Q | 1 |
| Maggi, CA; Morbidelli, L; Parenti, A; Santicioli, P; Ziche, M | 1 |
| Hou, YS; Lee, SS; Teng, CM; Yu, SM | 1 |
| Abe, S; Kanaide, H; Nakamura, M; Nishimura, J | 1 |
| Donatucci, CF; Hsu, GL; Lue, TF; Martinez-Piñeiro, L; Tanagho, EA; Trigo-Rocha, F | 1 |
| Kamei, K; Kuriyama, H; Nabata, H | 1 |
| Okamoto, K; Sakuta, H; Watanabe, Y | 1 |
| Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC | 1 |
| Andersson, KE; Persson, K; Waldeck, K | 1 |
| Hohn, J; Papp, JG; Pataricza, J; Penke, B; Toth, GK | 1 |
| Karaki, H; Mitsui-Saito, M; Ozaki, H; Trongvanichnam, K | 1 |
| McCulloch, AI; Randall, MD | 1 |
| Brading, AF; Teramoto, N | 1 |
| Norisue, M; Okabe, E; Todoki, K | 1 |
| Armstead, WM | 4 |
| Kinoshita, M; Liu, Q; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M; Takaoka, A | 1 |
| Ishiguro, S; Matsuyama, T; Nishio, A; Sakaguchi, H | 1 |
| Fullerton, DA; McIntyre, RC; Meldrum, DR; Sheridan, BC | 1 |
| Cogolludo, AL; Pérez-Vizcaíno, F; Tamargo, J; Villamor, E | 1 |
| Bryan, RM; Pelligrino, DA; Wang, Q | 1 |
| Balfagón, G; Ferrer, M; Marín, J; Tejera, N | 1 |
| Cogolludo, AL; Fajardo, S; Ibarra, M; Pérez-Vizcaíno, F; Tamargo, J | 1 |
| Chen, SJ; Wu, CC; Yen, MH | 1 |
| Cogolludo, AL; Fajardo, S; Ibarra, M; López-López, JG; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá-Arnáez, F | 1 |
| Chen, IJ; Chiang, LC; Lin, CY; Lin, RJ; Shen, KP; Wu, BN | 1 |
| Brading, AF; Hashitani, H; Suzuki, H | 1 |
| Belmadani, S; Lucchesi, PA; Matrougui, K; Palen, DI | 1 |
| Brand, M; Deussen, A | 1 |
| Al-Karagholi, MA; Ashina, M; Kokoti, L | 1 |
1 review(s) available for cromakalim and cyclic gmp
| Article | Year |
|---|---|
Latest Insights into the Pathophysiology of Migraine: the ATP-Sensitive Potassium Channels.
Topics: Animals; Bronchodilator Agents; Cromakalim; Cyclic AMP; Cyclic GMP; Drug Delivery Systems; Humans; KATP Channels; Migraine Disorders; Potassium Channel Blockers | 2020 |
44 other study(ies) available for cromakalim and cyclic gmp
| Article | Year |
|---|---|
Molecular mechanism of action of nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Niacinamide; Nicorandil; Nitroglycerin; Nitroprusside; Pyrroles; Vasodilation; Vasodilator Agents | 1992 |
Inhibitory action of the potassium channel opener BRL 38227 on agonist-stimulated phosphoinositide metabolism in bovine tracheal smooth muscle.
Topics: Animals; Benzopyrans; Cattle; Cromakalim; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Inositol Phosphates; Muscle, Smooth; Phosphatidylinositols; Phosphodiesterase Inhibitors; Potassium Channels; Pyrroles; Trachea | 1992 |
Similarities between effects of superoxide-mediated endothelium-derived relaxing factor and cromakalim.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Cyclic GMP; Female; Hypoxanthine; Hypoxanthines; Male; Mesenteric Arteries; Nitric Oxide; Pyrroles; Rabbits; Rubidium; Superoxides; Vasodilation; Vasodilator Agents; Xanthine Oxidase | 1992 |
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide; Guanidines; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Niacinamide; Nicorandil; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Sensitivity and Specificity; Vasodilator Agents | 1992 |
Potassium channel openers, NIP-121 and cromakalim, enhance the relaxation induced by sodium nitroprusside in the guinea-pig isolated trachea.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Drug Interactions; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles; SRS-A; Trachea; Vasodilator Agents | 1992 |
Vasorelaxation of rat thoracic aorta caused by two Ca(2+)-channel blockers, HA-22 and HA-23.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Caffeine; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Nifedipine; Pyrans; Pyrazoles; Pyrroles; Rats; Rats, Inbred Strains; Vasodilation; Verapamil | 1992 |
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Aorta, Thoracic; Benzofurans; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Quinolines; Rats; Rats, Inbred Strains; Verapamil | 1992 |
The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Diazoxide; Glyburide; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Minoxidil; Muscle, Smooth, Vascular; Portal Vein; Potassium Channels; Potassium Radioisotopes; Pyrroles; Rabbits; Rats; Rats, Inbred Strains; Rubidium Radioisotopes | 1990 |
Mechanisms of inhibitory effects of CD-349 and K(+)-channel activators on noradrenaline-induced contraction and changes in levels of cyclic GMP in rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Calcium Channel Agonists; Calcium Channel Blockers; Cromakalim; Cyclic GMP; Dihydropyridines; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains | 1990 |
Specificity of action of the novel antihypertensive agent, BRL 34915, as a potassium channel activator. Comparison with nicorandil.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Antihypertensive Agents; Apamin; Benzopyrans; Binding Sites; Cromakalim; Cyclic AMP; Cyclic GMP; Inositol Phosphates; Ion Channels; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrendipine; Potassium; Pyrroles; Rats; Rats, Inbred Strains; Rubidium; Tetraethylammonium Compounds | 1987 |
Endothelium-dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Cyclic GMP; Endothelium, Vascular; Ferricyanides; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Microscopy, Electron; Nitroprusside; Norepinephrine; Potassium Chloride; Pyrroles; Rats; Rats, Inbred Strains; Rubidium Radioisotopes | 1988 |
The lack of involvement of cyclic nucleotides in the smooth muscle relaxant action of BRL 34915.
Topics: Animals; Antihypertensive Agents; Apamin; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Guinea Pigs; Hemoglobins; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Pyrroles; Rabbits | 1988 |
The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
The inhibitory mechanisms of nicorandil in isolated rat urinary bladder and femoral artery.
Topics: Acetylcholine; Animals; Benzopyrans; Cromakalim; Cyclic GMP; Electric Stimulation; Femoral Artery; Guanylate Cyclase; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Urinary Bladder; Vasodilator Agents | 1995 |
Calcitonin gene-related peptide selectively increases cAMP levels in the guinea-pig ureter.
Topics: Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Drug Interactions; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Potassium Channels; Pyrroles; Ureter | 1995 |
Mechanisms of vasorelaxation induced by N-allylsecoboldine in rat thoracic aorta.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Aorta, Thoracic; Aporphines; Benzopyrans; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphatidylinositols; Potassium; Pyrroles; Rats; Rats, Wistar; Vasodilator Agents; Verapamil | 1994 |
Effects of nicorandil on cytosolic calcium concentrations and on tension development in the rabbit femoral artery.
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Cyclic GMP; Femoral Artery; Glyburide; In Vitro Techniques; Male; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Potassium Channels; Pyrroles; Rabbits; Vasodilation; Vasodilator Agents | 1994 |
Intracellular mechanism of penile erection in monkeys.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Ethylmaleimide; Macaca nemestrina; Male; Methylene Blue; Nitroprusside; Penile Erection; Penis; Phosphodiesterase Inhibitors; Purinones; Pyrroles; Ultrasonography | 1994 |
Effects of KC 399, a novel ATP-sensitive K+ channel opener, on electrical and mechanical responses in dog tracheal smooth muscle.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbachol; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Potassium Channels; Pyrroles; Trachea | 1994 |
Modification by cGMP of glibenclamide-sensitive K+ currents in Xenopus oocytes.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Female; Glyburide; In Vitro Techniques; Membrane Potentials; Methylene Blue; Niacinamide; Nicorandil; Nitroprusside; Oocytes; Potassium Channels; Pyridines; Pyrroles; Xenopus laevis | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents | 1993 |
Effects of KRN2391, a novel vasodilator acting as a nitrate and a K+ channel opener, on the rabbit lower urinary tract.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Electrophysiology; Female; Hypoglycemic Agents; Molsidomine; Muscle Relaxation; Muscle, Smooth; Pyridines; Pyrroles; Rabbits; Urethra; Vasodilator Agents | 1995 |
Effect of selective inhibition of potassium channels on vasorelaxing response to cromakalim, nitroglycerin and nitric oxide of canine coronary arteries.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; In Vitro Techniques; Male; Nitric Oxide; Nitroglycerin; Peptides; Potassium Channel Blockers; Potassium Chloride; Pyrroles; Vasodilation; Vasodilator Agents | 1995 |
Effects of chronic oral administration of levcromakalim on in vitro contractile responses of arterial smooth muscle.
Topics: Animals; Aorta; Benzopyrans; Calcium Channel Blockers; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Pyrroles; Rats; Rats, Inbred SHR; Rats, Wistar; Vasodilator Agents; Verapamil | 1996 |
Modulation of vasorelaxant responses to potassium channel openers by basal nitric oxide in the rat isolated superior mesenteric arterial bed.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Guanidines; In Vitro Techniques; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Papaverine; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Stereoisomerism; Theophylline; Vasodilation; Vasodilator Agents | 1996 |
Nicorandil activates glibenclamide-sensitive K+ channels in smooth muscle cells of pig proximal urethra.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Cyclic GMP; Female; Glyburide; Membrane Potentials; Muscle, Smooth; Niacinamide; Nicorandil; Potassium Channels; Pyrroles; Swine; Urethra | 1997 |
Inhibition by hydroxyl radicals of calcitonin gene-related peptide-mediated neurogenic vasorelaxation in isolated canine lingual artery.
Topics: Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Cromakalim; Cyclic GMP; Dogs; Female; Humans; Hydroxyl Radical; In Vitro Techniques; Male; Potassium Channels; Pyrroles; Vasodilation | 1997 |
Role of activation of calcium-sensitive K+ channels in NO- and hypoxia-induced pial artery vasodilation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Arterioles; Benzimidazoles; Benzopyrans; Cerebral Arteries; Cromakalim; Cyclic GMP; Female; Hypoxia; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Penicillamine; Pia Mater; Potassium Channels; Pyrroles; S-Nitroso-N-Acetylpenicillamine; Swine; Vasodilation; Vasodilator Agents | 1997 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Pyrroles; Vasodilator Agents | 1997 |
Ex vivo study of the increased sensitivity to NO of endothelium-denuded thoracic aortas isolated from dietary magnesium-deficient rats.
Topics: Animals; Aorta, Thoracic; Cromakalim; Cyclic GMP; Diet; Endothelium, Vascular; In Vitro Techniques; Magnesium Deficiency; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Isoproterenol; KATP Channels; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Tolbutamide; Vasodilation | 1997 |
Role of K+ channel opening and stimulation of cyclic GMP in the vasorelaxant effects of nicorandil in isolated piglet pulmonary and mesenteric arteries: relative efficacy and interactions between both pathways.
Topics: Animals; Cromakalim; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Niacinamide; Nicorandil; Nitroprusside; Potassium Channels; Pulmonary Artery; Swine; Vasodilator Agents; Verapamil | 1998 |
Calcium-dependent and ATP-sensitive potassium channels and the 'permissive' function of cyclic GMP in hypercapnia-induced pial arteriolar relaxation.
Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Blood Pressure; Calcium; Carbon Dioxide; Cerebral Arteries; Cromakalim; Cyclic GMP; Glyburide; Hydrogen-Ion Concentration; Hypercapnia; Indazoles; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Penicillamine; Peptides; Pia Mater; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Substrate Specificity; Vasodilation | 1998 |
Relationship among NO, the KATP channel, and opioids in hypoxic pial artery dilation.
Topics: Adenosine Triphosphate; Animals; Arteries; Blood Pressure; Calcitonin Gene-Related Peptide; Cromakalim; Cyclic GMP; Female; Glyburide; Hypoxia; Male; Nitric Oxide; Opioid Peptides; Pia Mater; Potassium Channels; Swine; Vasodilation; Vasodilator Agents | 1998 |
Effect of age on the vasorelaxation elicited by cromakalim. Role of K+ channels and cyclic GMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Aorta, Thoracic; Cromakalim; Cyclic GMP; Endothelium, Vascular; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Muscle Contraction; Potassium Channels; Rabbits; Vasodilation; Vasodilator Agents | 1998 |
Superoxide generation links protein kinase C activation to impaired ATP-sensitive K+ channel function after brain injury.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Arterioles; Brain; Brain Chemistry; Brain Injuries; Calcitonin Gene-Related Peptide; Carrier Proteins; Cerebral Arteries; Cromakalim; Cyclic GMP; Enzyme Activation; Female; Male; Membrane Proteins; Nitroprusside; Oxygen; Pia Mater; Potassium Channels; Protein Kinase C; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins; Superoxides; Swine; Vasodilation; Vasodilator Agents; Vesicular Transport Proteins; Xanthine Oxidase | 1999 |
Effects of nicorandil as compared to mixtures of sodium nitroprusside and levcromakalim in isolated rat aorta.
Topics: Animals; Aorta; Cromakalim; Cyclic GMP; Glyburide; In Vitro Techniques; Male; Nicorandil; Nitroprusside; Norepinephrine; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1999 |
Age-dependent impairment of K(ATP) channel function following brain injury.
Topics: Aging; Animals; Animals, Newborn; Arterioles; Brain; Brain Injuries; Calcitonin Gene-Related Peptide; Cerebrovascular Circulation; Cromakalim; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Female; Male; Nitric Oxide Donors; Penicillamine; Peptides, Cyclic; Pia Mater; Potassium Channels; S-Nitroso-N-Acetylpenicillamine; Swine; Vasodilation | 1999 |
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Apamin; Calcium; Charybdotoxin; Cromakalim; Cyclic GMP; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred WKY | 1999 |
Vasodilator effects of sodium nitroprusside, levcromakalim and their combination in isolated rat aorta.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Cromakalim; Cyclic GMP; Drug Combinations; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Potassium Channels; Rats; Rats, Wistar; Vasodilator Agents | 1999 |
A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Cromakalim; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Heart Rate; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphoric Diester Hydrolases; Piperidines; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Solubility; Vasodilation; Vasodilator Agents; Xanthine; Xanthines | 2001 |
Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; Charybdotoxin; Colforsin; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Fura-2; Guinea Pigs; Isotonic Contraction; Male; Mechanotransduction, Cellular; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Transducers; Urinary Bladder | 2004 |
Role of SHP-1, Kv.1.2, and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Cromakalim; Cyclic GMP; Enzyme Inhibitors; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Kv1.2 Potassium Channel; Male; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Okadaic Acid; Penicillamine; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2005 |
Vardenafil increases coronary flow response to hypercapnic acidosis in isolated guinea pig heart.
Topics: Acidosis; Animals; Coronary Circulation; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Hypercapnia; Imidazoles; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Piperazines; Signal Transduction; Sulfones; Triazines; Vardenafil Dihydrochloride; Vasodilation | 2007 |