Page last updated: 2024-08-25

cromakalim and bradykinin

cromakalim has been researched along with bradykinin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's22 (73.33)18.2507
2000's8 (26.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Illiano, S; Nagao, T; Vanhoutte, PM2
Bennett, T; Gardiner, SM1
Adams, DJ; Rusko, J; Tanzi, F; van Breemen, C1
Cohen, RA; Cowan, CL1
Chapnick, BM; Pawloski, JR1
Daut, J; Goedel-Meinen, L; Günther, K; Maier-Rudolph, W; Mehrke, G; von Beckerath, N1
Kadlec, O; Masek, K; Seferna, I; Sevcík, J1
Busse, R; Lückhoff, A1
Ishimura, Y; Katoh, I; Masuda, Y; Oka, M; Yoshizumi, M1
Advenier, C; Martin, CA1
Kam, KL; Pfaffendorf, M; van Zwieten, PA1
Mombouli, JV; Nakashima, M; Taylor, AA; Vanhoutte, PM1
Cohen, GA; Hauth, TA; Hyman, AL; Lippton, HL1
Bennett, T; Fallgren, B; Gardiner, SM; Kemp, PA; March, JE1
Fulton, D; McGiff, JC; Mieyal, P; Quilley, J; Rapacon, M1
Fulton, D; Kaminski, P; McGiff, JC; Quilley, J; Wolin, MS1
Bizub, DM; Gauthier-Rein, KM; Lombard, JH; Rusch, NJ1
Champion, HC; Kadowitz, PJ1
Li, L; Paakkari, I; Vaali, K; Vapaatalo, H1
Alva, M; Carretero, OA; Pomposiello, S; Rhaleb, NE1
Man, RY; Quan, A; Teoh, H2
Cocks, TM; Drummond, GR; Selemidis, S1
Edwards, G; Félétou, M; Gardener, MJ; Glen, CD; Richards, GR; Vanhoutte, PM; Weston, AH1
Fujiki, T; Hirakawa, Y; Kubota, H; Kunihiro, I; Matoba, T; Morikawa, K; Mukai, Y; Shimokawa, H; Takeshita, A1
Busija, DW; Erdös, B; Miller, AW1
Dowell, FJ; Martin, W; McNeish, AJ; Nelli, S; Wilson, WS1
Farias, NC; Feres, T; Paiva, AC; Paiva, TB1
Cocks, T; Selemidis, S1

Other Studies

30 other study(ies) available for cromakalim and bradykinin

ArticleYear
Calmidazolium, a calmodulin inhibitor, inhibits endothelium-dependent relaxations resistant to nitro-L-arginine in the canine coronary artery.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Arginine; Benzopyrans; Bradykinin; Calcimycin; Calmodulin; Coronary Vessels; Cromakalim; Dogs; Endothelium, Vascular; Ethanolamines; Imidazoles; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nebivolol; Nitric Oxide; Nitroarginine; Pyrroles; Vasodilator Agents

1992
Calmodulin antagonists inhibit endothelium-dependent hyperpolarization in the canine coronary artery.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Animals; Benzopyrans; Bradykinin; Calcimycin; Calmodulin; Coronary Vessels; Cromakalim; Dogs; Endothelium, Vascular; Female; Fendiline; Imidazoles; Male; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channels; Pyrroles

1992
Involvement of nitric oxide in the regional haemodynamic effects of perindoprilat and captopril in hypovolaemic Brattleboro rats.
    British journal of pharmacology, 1992, Volume: 107, Issue:4

    Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Benzopyrans; Blood Volume; Bradykinin; Captopril; Cromakalim; Hemodynamics; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrroles; Random Allocation; Rats; Rats, Brattleboro; Vasodilation; Vasodilator Agents

1992
Calcium-activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block.
    The Journal of physiology, 1992, Volume: 455

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta; Benzopyrans; Bradykinin; Calcium; Cromakalim; Egtazic Acid; Endothelium, Vascular; Glyburide; Membrane Potentials; Potassium; Potassium Channels; Pyrroles; Quaternary Ammonium Compounds; Rabbits; Vasodilator Agents

1992
Different mechanisms of relaxation of pig coronary artery to bradykinin and cromakalim are distinguished by potassium channel blockers.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Benzopyrans; Bradykinin; Calcium; Coronary Vessels; Cromakalim; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Potassium Channels; Procaine; Pyrroles; Quinine; Swine; Tetraethylammonium; Tetraethylammonium Compounds

1992
LTD4 and bradykinin evoke endothelium-dependent relaxation of the renal vein: dissimilar mechanisms.
    The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 2

    Topics: Animals; Arginine; Benzopyrans; Bradykinin; Chromones; Cromakalim; Dogs; Endothelium, Vascular; Glyburide; Hemoglobins; Male; Methylene Blue; omega-N-Methylarginine; Pyrroles; Renal Veins; SRS-A; Vasodilation; Vasodilator Agents; Vasomotor System

1991
Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels.
    Science (New York, N.Y.), 1990, Mar-16, Volume: 247, Issue:4948

    Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Bradykinin; Coronary Vessels; Cromakalim; Endothelium, Vascular; Glyburide; Guinea Pigs; Hypoxia; In Vitro Techniques; Ischemia; Potassium Channels; Pyrroles; Vasodilation

1990
Non-junctional modulation of neurogenic twitches of the guinea-pig ileum by some peptides and other compounds in the triple bath.
    General physiology and biophysics, 1990, Volume: 9, Issue:5

    Topics: Action Potentials; Animals; Benzopyrans; Bradykinin; Capsaicin; Cromakalim; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neural Conduction; Neurotensin; Peptides; Pyrroles; Vasoactive Intestinal Peptide

1990
Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Benzopyrans; Bradykinin; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Cromakalim; Endothelium, Vascular; Homeostasis; Membrane Potentials; Nitric Oxide; Parasympatholytics; Potassium Channels; Pyrroles; Thimerosal

1990
Effects of the potassium channel openers cromakalim and pinacidil on catecholamine secretion and calcium mobilization in cultured bovine adrenal chromaffin cells.
    Biochemical pharmacology, 1994, May-18, Volume: 47, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Barium; Benzopyrans; Bradykinin; Calcimycin; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Cromakalim; Guanidines; Histamine; Pinacidil; Potassium; Potassium Channels; Pyrroles; Rubidium Radioisotopes

1994
Effects of cromakalim on bradykinin-, histamine- and substance P-induced airway microvascular leakage in the guinea-pig.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Animals; Benzopyrans; Bradykinin; Bronchi; Capillary Permeability; Cromakalim; Electric Stimulation; Evans Blue; Female; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Lung; Male; Muscle Contraction; Muscle, Smooth; Pyrroles; Respiratory System; Substance P; Trachea

1993
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
    Blood pressure, 1994, Volume: 3, Issue:6

    Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glyburide; Histamine; Hypertension; Male; Mesenteric Arteries; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents

1994
Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Benzopyrans; Bradykinin; Calcimycin; Child; Coronary Vessels; Cromakalim; Dinoprost; Endothelium, Vascular; Glyburide; Humans; In Vitro Techniques; Indoles; Indomethacin; Infant; Male; Membrane Potentials; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Pyrroles; Vasodilator Agents

1993
Functional evidence for different endothelin receptors in the lung.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anesthesia; Animals; Benzopyrans; Bradykinin; Cats; Cromakalim; Endothelins; Female; Glyburide; Hemodynamics; Lung; Male; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pulmonary Gas Exchange; Pyrroles; Receptors, Endothelin; Tachyphylaxis; Vascular Resistance; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Viper Venoms

1993
Effects of glibenclamide on the regional haemodynamic actions of alpha-trinositol and its influence on responses to vasodilators in conscious rats.
    British journal of pharmacology, 1996, Volume: 117, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Benzopyrans; Blood Glucose; Bradykinin; Cromakalim; Glyburide; Hemodynamics; Hindlimb; Hypoglycemic Agents; Inositol Phosphates; Male; Nitroprusside; Platelet Aggregation Inhibitors; Potassium Channels; Pyrroles; Rats; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vasodilator Agents

1996
Contribution of calcium-activated potassium channels to the vasodilator effect of bradykinin in the isolated, perfused kidney of the rat.
    British journal of pharmacology, 1996, Volume: 118, Issue:6

    Topics: Adenosine Triphosphate; Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Endothelium, Vascular; In Vitro Techniques; Kidney; Male; Nitric Oxide; Nitroprusside; Potassium Channels; Prostaglandin Antagonists; Pyrroles; Rats; Rats, Wistar; Renal Circulation; Vasodilation; Vasodilator Agents

1996
Evidence against a cytochrome P450-derived reactive oxygen species as the mediator of the nitric oxide-independent vasodilator effect of bradykinin in the perfused heart of the rat.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Arachidonic Acid; Benzimidazoles; Benzopyrans; Bradykinin; Cromakalim; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Heart; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Indomethacin; Kidney Cortex; Luminescent Measurements; Male; Microsomes; Nitric Oxide; Nitroarginine; Parasympatholytics; Perfusion; Pyrazines; Pyrroles; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Vasodilator Agents

1997
Hypoxia-induced hyperpolarization is not associated with vasodilation of bovine coronary resistance arteries.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Acetylcholine; Animals; Benzopyrans; Bradykinin; Calcium; Cattle; Coronary Vessels; Cromakalim; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Membrane Potentials; Microelectrodes; Microscopy, Video; Oxygen; Perfusion; Pyrroles; Vascular Resistance; Vasodilation; Vasodilator Agents

1997
Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Albuterol; Alprostadil; Analysis of Variance; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Bradykinin; Cats; Cromakalim; Endothelium, Vascular; Female; Glyburide; Heart Rate; Hindlimb; Hydrazines; Isradipine; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Nitroprusside; Norepinephrine; Penicillamine; Prostaglandin Endoperoxides, Synthetic; Pyrroles; S-Nitroso-N-Acetylpenicillamine; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Thromboxane A2; Vasoactive Intestinal Peptide; Vasodilation; Vasodilator Agents

1997
Bradykinin, lemakalim and sodium nitroprusside relax the mouse trachea in vitro by different mechanisms.
    Life sciences, 1997, Volume: 61, Issue:7

    Topics: Animals; Benzopyrans; Bradykinin; Cromakalim; Female; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; Nitroprusside; Potassium Channels; Pyrroles; Trachea

1997
Reactive oxygen species: role in the relaxation induced by bradykinin or arachidonic acid via EDHF in isolated porcine coronary arteries.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:4

    Topics: Animals; Arachidonic Acid; Biological Factors; Bradykinin; Catalase; Coronary Vessels; Cromakalim; Drug Interactions; Endothelium; In Vitro Techniques; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroglycerin; Reactive Oxygen Species; Superoxide Dismutase; Swine; Vasodilator Agents

1999
Acute exposure to a low level of testosterone impairs relaxation in porcine coronary arteries.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:10

    Topics: Animals; Bradykinin; Calcimycin; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Estradiol; In Vitro Techniques; Ionophores; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Swine; Testosterone; Vasodilator Agents

1999
Apamin-sensitive, non-nitric oxide (NO) endothelium-dependent relaxations to bradykinin in the bovine isolated coronary artery: no role for cytochrome P450 and K+.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Animals; Apamin; Arachidonic Acid; Arachidonic Acids; Biological Factors; Bradykinin; Cattle; Coronary Vessels; Cromakalim; Cyclohexanones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Ouabain; Oxazines; Potassium; Potassium Chloride; Protease Inhibitors

2000
Acute impairment of relaxation by low levels of testosterone in porcine coronary arteries.
    Cardiovascular research, 2000, Volume: 45, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Androgen Receptor Antagonists; Animals; Bradykinin; Calcimycin; Coronary Vessels; Cromakalim; Cycloheximide; Cyproterone; Dactinomycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flutamide; Ionophores; Male; Nitroprusside; Swine; Testosterone; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2000
Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Animals; Bicarbonates; Biological Factors; Bradykinin; Buffers; Coronary Vessels; Cromakalim; Endothelium, Vascular; Epoprostenol; Glyburide; HEPES; In Vitro Techniques; Indomethacin; Isotonic Solutions; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroarginine; Peptides; Sodium Chloride; Substance P; Swine; Time Factors; Vasodilator Agents

2001
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries.
    Biochemical and biophysical research communications, 2002, Jan-25, Volume: 290, Issue:3

    Topics: Aged; Bradykinin; Catalase; Cromakalim; Culture Techniques; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Gap Junctions; Glycyrrhetinic Acid; Humans; Hydrogen Peroxide; Male; Membrane Potentials; Mesenteric Arteries; Middle Aged; Sulfaphenazole; Vasodilation

2002
Alterations in KATP and KCa channel function in cerebral arteries of insulin-resistant rats.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cerebral Arteries; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Hyperinsulinism; Hyperlipidemias; Hypertriglyceridemia; In Vitro Techniques; Insulin Resistance; Lipoproteins, HDL; Male; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2002
Differential effects of ascorbate on endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation in the bovine ciliary vascular bed and coronary artery.
    British journal of pharmacology, 2003, Volume: 138, Issue:6

    Topics: Acetylcholine; Animals; Aqueous Humor; Ascorbate Oxidase; Biological Factors; Bradykinin; Cattle; Ciliary Arteries; Ciliary Body; Collateral Circulation; Coronary Circulation; Cromakalim; Dose-Response Relationship, Drug; Nitric Oxide Synthase; Potassium Channels, Calcium-Activated; Vasodilation

2003
Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Bradykinin; Brimonidine Tartrate; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Kallidin; Lipopolysaccharides; Male; Membrane Potentials; Peptides; Potassium Channels, Calcium-Activated; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Wistar; Vasodilator Agents

2004
Smooth muscle mediates circumferential conduction of hyperpolarization and relaxation to focal endothelial cell activation in large coronary arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Apamin; Biological Factors; Bradykinin; Charybdotoxin; Coronary Vessels; Cromakalim; Electrophysiology; Endothelial Cells; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Potassium Channels, Calcium-Activated; Sulfaphenazole; Swine; Thrombin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2007