Page last updated: 2024-08-24

cremophor el and saquinavir

cremophor el has been researched along with saquinavir in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Burhenne, J; Ding, R; Fricker, R; Haefeli, WE; Martin-Facklam, M; Mikus, G; Walter-Sack, I	1
Kataoka, M; Masaoka, Y; Sakuma, S; Yamashita, S; Yokoyama, T	1
Banba, H; Kumagai, Y; Kusuhara, H; Maeda, K; Sugiyama, Y; Takayama, K; Takeda-Morishita, M; Tomaru, A	1

Trials

2 trial(s) available for cremophor el and saquinavir

Article	Year
Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL. British journal of clinical pharmacology, 2002, Volume: 53, Issue:6 Topics: Administration, Oral; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Glycerol; HIV Protease Inhibitors; Humans; Male; Pharmaceutical Vehicles; Saquinavir	2002
Effects of Cremophor EL on the absorption of orally administered saquinavir and fexofenadine in healthy subjects. Drug metabolism and pharmacokinetics, 2015, Volume: 30, Issue:3 Topics: Absorption, Physiological; Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Excipients; Glycerol; Healthy Volunteers; Humans; Male; Saquinavir; Substrate Specificity; Terfenadine	2015

Article

Year

Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL.

British journal of clinical pharmacology, 2002, Volume: 53, Issue:6

Topics: Administration, Oral; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Glycerol; HIV Protease Inhibitors; Humans; Male; Pharmaceutical Vehicles; Saquinavir

2002

Effects of Cremophor EL on the absorption of orally administered saquinavir and fexofenadine in healthy subjects.

Drug metabolism and pharmacokinetics, 2015, Volume: 30, Issue:3

Topics: Absorption, Physiological; Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Excipients; Glycerol; Healthy Volunteers; Humans; Male; Saquinavir; Substrate Specificity; Terfenadine

2015

Other Studies

1 other study(ies) available for cremophor el and saquinavir

Article	Year
Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Nov-20, Volume: 44, Issue:4 Topics: Algorithms; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Drug Interactions; Erythromycin; Gene Expression; Glycerol; Humans; Intestinal Absorption; Loperamide; Models, Biological; Pharmaceutical Preparations; Propanolamines; Puromycin; Quinidine; Saquinavir; Solubility; Surface-Active Agents; Terfenadine; Verapamil; Vinblastine	2011

Article

Year

Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Nov-20, Volume: 44, Issue:4

Topics: Algorithms; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Drug Interactions; Erythromycin; Gene Expression; Glycerol; Humans; Intestinal Absorption; Loperamide; Models, Biological; Pharmaceutical Preparations; Propanolamines; Puromycin; Quinidine; Saquinavir; Solubility; Surface-Active Agents; Terfenadine; Verapamil; Vinblastine

2011