Compounds > cp094

Page last updated: 2024-08-25

cp094 and deferoxamine

cp094 has been researched along with deferoxamine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	14 (93.33)	18.2507
2000's	1 (6.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G	1
Crichton, RR; Florence, A; Peters, TJ; Ward, RJ	1
Hider, RC; Hoyes, KP; Porter, JB	1
Bergeron, RJ; Creary, EA; Luchetta, G; Peter, HH; Streiff, RR; Wiegand, J	1
Dobbin, P; Hershko, C; Hider, RC; Link, G; Peter, HH; Pinson, A	1
Olivieri, NF; Parkes, JG; Randell, EW; Templeton, DM	1
Boelaert, J; Papavassiliou, P; Soteriadou, K; Voyiatzaki, C	1
Abeysinghe, RD; Epemolu, O; Hider, RC; Hoyes, KP; Porter, JB; Singh, S	1
Hershko, C; Link, G; Pinson, A	1
Boelaert, JR; Crichton, RR; de Locht, M; Schneider, YJ; Van Cutsem, J	1
Hoyes, KP; Porter, JB	1
Cammack, R; Cooper, CE; Hider, RC; Hoyes, KP; Lynagh, GR; Porter, JB	1
Cable, H; Lloyd, JB	1
Berthon, G; Biron, F; Desroches, S	1
Curnow, A; Pye, A	1

Reviews

1 review(s) available for cp094 and deferoxamine

Article	Year
Lessons from preclinical and clinical studies with 1,2-diethyl-3-hydroxypyridin-4-one, CP94 and related compounds. Advances in experimental medicine and biology, 1994, Volume: 356 Topics: Animals; beta-Thalassemia; Cell Line; Deferoxamine; Guinea Pigs; Humans; Iron; Iron Chelating Agents; Mice; Pyridones; Rats; Structure-Activity Relationship; Tumor Cells, Cultured	1994

Other Studies

14 other study(ies) available for cp094 and deferoxamine

Article	Year
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. Journal of medicinal chemistry, 1993, Aug-20, Volume: 36, Issue:17 Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship	1993
Studies of in vivo iron mobilization by chelators in the ferrocene-loaded rat. Biochemical pharmacology, 1992, Sep-25, Volume: 44, Issue:6 Topics: Animals; Brain; Deferiprone; Deferoxamine; Disease Models, Animal; Ferrous Compounds; Heart; Hemochromatosis; Iron; Iron Chelating Agents; Liver; Male; Metallocenes; Organometallic Compounds; Pyridones; Rats; Rats, Wistar; Spleen; Subcellular Fractions	1992
Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines. Cancer research, 1992, Sep-01, Volume: 52, Issue:17 Topics: Cell Cycle; Cell Survival; Deferoxamine; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Iron Chelating Agents; Neoplasm Proteins; Pyridones; Ribonucleotide Reductases; RNA, Neoplasm; Tumor Cells, Cultured	1992
A comparison of the iron-clearing properties of 1,2-dimethyl-3-hydroxypyrid-4-one, 1,2-diethyl-3-hydroxypyrid-4-one, and deferoxamine. Blood, 1992, Apr-01, Volume: 79, Issue:7 Topics: Animals; Bile; Cebus; Deferiprone; Deferoxamine; Feces; Iron; Iron Chelating Agents; Kinetics; Male; Pyridones; Rats; Rats, Inbred Strains	1992
Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: studies in rat heart cells in culture. Blood, 1991, May-01, Volume: 77, Issue:9 Topics: Animals; Cell Membrane; Cells, Cultured; Deferoxamine; Iron; Iron Chelating Agents; Kinetics; Lipid Peroxidation; Malondialdehyde; Myocardium; Pyridones; Rats	1991
Modulation by iron loading and chelation of the uptake of non-transferrin-bound iron by human liver cells. Biochimica et biophysica acta, 1995, Apr-13, Volume: 1243, Issue:3 Topics: Biological Transport; Carcinoma, Hepatocellular; Cell Death; Deferiprone; Deferoxamine; Diffusion; Ferric Compounds; Humans; Iron; Iron Chelating Agents; Iron Radioisotopes; Kinetics; Liver; Liver Neoplasms; Nitrilotriacetic Acid; Pyridones; Quaternary Ammonium Compounds; Transferrin; Tumor Cells, Cultured	1995
Effect of iron chelation on the in-vitro growth of Leishmania promastigotes. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:1 Topics: Animals; Deferiprone; Deferoxamine; DNA; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Iodine Radioisotopes; Iron Chelating Agents; Leishmania infantum; Leishmania major; Pyridones; Transferrin	1995
Ability of the orally effective iron chelators dimethyl- and diethyl-hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells. Blood, 1994, May-01, Volume: 83, Issue:9 Topics: 5'-Nucleotidase; Administration, Oral; Animals; beta-N-Acetylhexosaminidases; Cells, Cultured; Deferiprone; Deferoxamine; Heart; Iron; Iron Chelating Agents; Lysosomes; Myocardium; Pyridones; Rats; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds	1994
Deferoxamine augments growth and pathogenicity of Rhizopus, while hydroxypyridinone chelators have no effect. Kidney international, 1994, Volume: 45, Issue:3 Topics: Animals; Deferiprone; Deferoxamine; Guinea Pigs; Iron; Iron Chelating Agents; Male; Mucormycosis; Pyridones; Rhizopus; Transferrin	1994
Subcellular distribution of desferrioxamine and hydroxypyridin-4-one chelators in K562 cells affects chelation of intracellular iron pools. British journal of haematology, 1993, Volume: 85, Issue:2 Topics: Cytosol; Deferoxamine; Humans; Iron; Iron Chelating Agents; Leukemia, Experimental; Molecular Weight; Pyridones; Subcellular Fractions; Tumor Cells, Cultured	1993
The relationship of intracellular iron chelation to the inhibition and regeneration of human ribonucleotide reductase. The Journal of biological chemistry, 1996, Aug-23, Volume: 271, Issue:34 Topics: Deferoxamine; Electron Spin Resonance Spectroscopy; Humans; Iron; Iron Chelating Agents; Pyridones; Ribonucleotide Reductases; Solubility; Tumor Cells, Cultured; Tyrosine	1996
Cellular uptake and release of two contrasting iron chelators. The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:2 Topics: Animals; Carbon Radioisotopes; Deferoxamine; In Vitro Techniques; Iodine Radioisotopes; Iron Chelating Agents; Povidone; Pyridones; Rats; Time Factors; Yolk Sac	1999
Aluminum speciation studies in biological fluids. Part 5. A quantitative investigation of A1(III) complex equilibria with desferrioxamine, 2,3-dihydroxybenzoic acid, Tiron, CP20 (L1), and CP94 under physiological conditions, and computer-aided assessment Journal of inorganic biochemistry, 1999, May-30, Volume: 75, Issue:1 Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aluminum; Animals; Body Fluids; Chelating Agents; Computer Simulation; Deferiprone; Deferoxamine; Humans; Hydroxybenzoates; Indicators and Reagents; Inflammation; Iron Chelating Agents; Ligands; Pyridones; Rabbits; Rats; Reproducibility of Results	1999
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2007, Volume: 26, Issue:2 Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Esters; Fibroblasts; Fluorescence; Humans; Iron Chelating Agents; Lung; Microscopy, Fluorescence; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Pyridones	2007