Page last updated: 2024-08-25

cp094 and aminolevulinic acid

cp094 has been researched along with aminolevulinic acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bown, SG; Chang, SC; MacRobert, AJ; Porter, JB1
Bech, O; MacRobert, AJ; Moan, J; Phillips, D1
Bown, SG; Curnow, A; MacRobert, AJ1
Curnow, A; Pye, A1
Campbell, S; Curnow, A; Pye, A1
Alyahya, R; Campbell, SM; Curnow, A; Horton, S; Morton, CA; Pye, A1
Curnow, A; Dodd, NJF; Dogra, Y; Ferguson, DCJ; Smerdon, GR; Winyard, PG1
Curnow, A; Perry, A; Wood, M1

Trials

2 trial(s) available for cp094 and aminolevulinic acid

ArticleYear
Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:8

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Cell Line, Tumor; Humans; In Vitro Techniques; Iron Chelating Agents; Middle Aged; Photochemotherapy; Photosensitizing Agents; Pilot Projects; Protoporphyrins; Pyridones; Skin Neoplasms

2008
Clinical investigation of the novel iron-chelating agent, CP94, to enhance topical photodynamic therapy of nodular basal cell carcinoma.
    The British journal of dermatology, 2008, Volume: 159, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Dose-Response Relationship, Drug; Female; Humans; Iron Chelating Agents; Male; Middle Aged; Pain; Photochemotherapy; Photosensitizing Agents; Pilot Projects; Pyridones; Skin Neoplasms; Treatment Outcome

2008

Other Studies

6 other study(ies) available for cp094 and aminolevulinic acid

ArticleYear
The efficacy of an iron chelator (CP94) in increasing cellular protoporphyrin IX following intravesical 5-aminolaevulinic acid administration: an in vivo study.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 38, Issue:2-3

    Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Female; Iron Chelating Agents; Kinetics; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Pyridones; Rats; Rats, Wistar; Spectrometry, Fluorescence; Urinary Bladder

1997
A hydroxypyridinone (CP94) enhances protoporphyrin IX formation in 5-aminolaevulinic acid treated cells.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 41, Issue:1-2

    Topics: Aminolevulinic Acid; Cell Line; Darkness; Humans; Iron Chelating Agents; Microscopy, Fluorescence; Molecular Structure; Prodrugs; Protoporphyrins; Pyridones; Spectrometry, Fluorescence

1997
Comparing and combining light dose fractionation and iron chelation to enhance experimental photodynamic therapy with aminolevulinic acid.
    Lasers in surgery and medicine, 2006, Volume: 38, Issue:4

    Topics: Aminolevulinic Acid; Animals; Colon; Colonic Neoplasms; Dose Fractionation, Radiation; Female; Fibrosarcoma; Iron Chelating Agents; Photochemotherapy; Photosensitizing Agents; Pyridones; Rats; Rats, Wistar

2006
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2007, Volume: 26, Issue:2

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Esters; Fibroblasts; Fluorescence; Humans; Iron Chelating Agents; Lung; Microscopy, Fluorescence; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Pyridones

2007
The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species.
    Redox biology, 2016, Volume: 9

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Survival; Histidine; Humans; Iron Chelating Agents; Metalloporphyrins; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Pyridones; Reactive Oxygen Species

2016
Improving in vitro photodynamic therapy through the development of a novel iron chelating aminolaevulinic acid prodrug.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 25

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Survival; Humans; Iron Chelating Agents; Photochemotherapy; Photosensitizing Agents; Prodrugs; Protoporphyrins; Pyridones; Skin Neoplasms

2019